Can disorganisation of semantic memory account for the abnormalities of thought in schizophrenia-a controlled experimental study.

Abstract:

BACKGROUND:Disorganisation of semantic memory could provide a cognitive explanation for the disturbances of thinking and reasoning in schizophrenia. In this study, we directly test this explanation by identifying patients with disorganised semantic categories and then examine how they use their knowledge about these same categories in an inductive reasoning task. METHOD:Experiment 1 utilised a semantic category-sorting task to identify patients with disorganisation of semantic memory. In Experiment 2, the patients with disorganised categories carried out a category-based inductive reasoning task. Accurate performance on this task requires access to well-organised semantic knowledge about the objects and categories used in Experiment 1. RESULTS:Patients with disorganised semantic categories in Experiment 1 did not demonstrate any difficulties or unusual responses when reasoning about the same categories in Experiment 2. CONCLUSION:Disorganisation of semantic memory may not be the primary cause of disturbed reasoning or thought in schizophrenia. Patients with schizophrenia tend to generate ad hoc categories, which are unsuited to the current context. Impaired performance on semantic memory tasks can arise from a misunderstanding of social context.

journal_name

Schizophr Res

journal_title

Schizophrenia research

authors

Green NE,Done DJ,Anthony SH,McKenna PJ,Ochocki M

doi

10.1016/j.schres.2003.12.003

subject

Has Abstract

pub_date

2004-10-01 00:00:00

pages

233-40

issue

2-3

eissn

0920-9964

issn

1573-2509

pii

S0920996404000039

journal_volume

70

pub_type

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