Visuospatial working memory deficits in adolescent onset schizophrenia.

Abstract:

:This study determines that visuospatial working memory (VSWM) deficits are evident in adolescent-onset schizophrenia, while the spatial strategy and spatial span components of VSWM are spared. These findings imply that frontal-striatal-parietal neural networks are dysfunctional in adolescent-onset schizophrenia, while mid-dorsolateral and ventrolateral PFC functions remain intact: the current conceptualisation of schizophrenia as a progressive neurodevelopmental disorder is consistent with these results.

journal_name

Schizophr Res

journal_title

Schizophrenia research

authors

Vance A,Hall N,Bellgrove MA,Casey M,Karsz F,Maruff P

doi

10.1016/j.schres.2006.04.025

subject

Has Abstract

pub_date

2006-10-01 00:00:00

pages

223-7

issue

1-3

eissn

0920-9964

issn

1573-2509

pii

S0920-9964(06)00174-5

journal_volume

87

pub_type

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