Abstract：
BACKGROUND:Injecting a neurotoxin virus into ovary of adult rats has provided morphologic evidence of a multisynaptic neural pathway between ovary and central nervous system (CNS). Vagus nerve is one of the pathways used by CNS to send and receive information to and from the ovary. METHODS:The present study analyzed whether or not vagal innervation of ovaries in prepubertal rats modulated, in a stimulatory fashion, functions of the ovary and whether the modulating function of these nerves was asymmetric. RESULTS:Animals vagotomized at 24 and 28 days of age showed delay in age of onset of puberty. Unilateral or bilateral vagotomy performed at 24 days of age did not modify ovulation rates or number of ova shed. In turn, bilateral vagotomy performed at 28 days of age resulted in a significant increase in number of ova shed by ovulating animals. Unilateral and bilateral vagotomy performed on day 24 or 28 resulted in a decrease in estradiol serum levels. Unilateral vagotomy performed on 24-day-old rats did not modify progesterone levels, while bilateral vagotomy on the same age group resulted in a significant increase of progesterone levels. In turn, unilateral and bilateral vagotomy performed on rats aged 28 days resulted in lower progesterone levels. CONCLUSIONS:Present results confirmed results of previous studies, indicating that interrupting ovarian innervation had an effect on regulation of ovarian functions by CNS and that these effects varied according to age at which denervation was performed.
journal_name
Arch Med Resjournal_title
Archives of medical researchauthors
Morales-Ledesma L,Betanzos-García R,Domínguez-Casalá Rdoi
10.1016/j.arcmed.2004.03.007subject
Has Abstractpub_date
2004-07-01 00:00:00pages
279-83issue
4eissn
0188-4409issn
1873-5487pii
S0188-4409(04)00058-Xjournal_volume
35pub_type
杂志文章abstract：BACKGROUND AND AIMS:The cardiac regulator of G-protein signaling 2 (RGS2) negatively regulates G-protein-coupled receptor signaling. The C1114G polymorphism reduces RGS2 gene expression. This molecular disorder may be one of the important factors influencing progress of neurally mediated syncope. The aim of the study w...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2009.02.005
更新日期：2009-04-01 00:00:00
abstract：:This study evaluated the attachment, chemoattractive, proliferative and mineralization inductive potential of a bovine cementum extract (CPE) on newborn murine dental follicle cells (MDFC) in vitro. Cementum extract was partially purified by DEAE-cellulose chromatography. A band representing an M(r) of 55,000 was exci...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：
更新日期：1997-10-01 00:00:00
abstract：BACKGROUND AND AIMS:Hypophosphatasia is a genetic disorder characterized by defective bone and tooth mineralization and a deficiency of serum and bone alkaline phosphatase activity. To date, few studies have identified gene mutations in Chinese patients with hypophosphatasia. We sought to characterize the clinical mani...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2012.01.004
更新日期：2012-01-01 00:00:00
abstract：:The expression of neurodegenerative diseases can be categorized into three main symptomatic domains: neurological, cognitive and, neuropsychiatric. This review focuses on the cognitive profile and neuropsychological assessment of Alzheimer's disease (AD). The topography and progression of brain neuropathology determin...
journal_title：Archives of medical research
pub_type： 杂志文章,评审
doi：10.1016/j.arcmed.2012.08.015
更新日期：2012-11-01 00:00:00
abstract：BACKGROUND:Thymectomy is considered the most effective treatment for achieving sustained improvement as well as remission in patients with myasthenia gravis (MG), and most neurologists favor the use of this procedure. The main focus of many current studies is to determine response-predicting factors. METHODS:Clinical ...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/s0188-4409(02)00405-8
更新日期：2002-11-01 00:00:00
abstract：BACKGROUND AND AIMS:High mobility group box 1 (HMGB1) plays an important role as a pro-inflammatory cytokine that regulates inflammation in various diseases. We hypothesized that hemin might reduce HMGB1 release through the induction of HO-1 in UVB-induced HaCaTs. METHODS:The effects of hemin on the release of HMGB1 i...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2017.10.007
更新日期：2017-07-01 00:00:00
abstract：BACKGROUND:The diuretic response has been shown to be a robust independent marker of cardiovascular outcomes in acute heart failure (ADHF) patients. The objectives of this clinical research, will aim are to: a) include diuresis in the formula for diuretic response (R-to-D); b) add to R-to-D the value of a pre-discharge...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2018.08.007
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND AND AIMS:We undertook this study to investigate the association between CT perfusion characteristics and differentiation grade in lung cancer, as well as the pathological basis of this association. METHODS:Seventy three patients received CT perfusion scan and pathological biopsy, and 30 of them were availab...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2010.11.005
更新日期：2010-11-01 00:00:00
abstract：BACKGROUND:Previous studies have reported vitamin D receptor (VDR) polymorphisms in multiple sclerosis (MS); however, the results remain contradictory. This study aimed to investigate the association between VDR polymorphisms and the risk of MS. METHODS:PubMed and Embase databases were searched to obtain eligible stud...
journal_title：Archives of medical research
pub_type： 杂志文章,meta分析
doi：10.1016/j.arcmed.2019.10.007
更新日期：2019-08-01 00:00:00
abstract：:A matrix metalloproteinase with selective affinity for collagen was identified and partially purified from normal rat kidney. A two-step purification procedure consisting of gel filtration and affinity chromatography on Sepharose 4B-collagen resulted in an increase in specific activity of more than 3,000 times. The pa...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：
更新日期：1995-10-01 00:00:00
abstract：BACKGROUND AND AIMS:Small cell lung cancer (SCLC) is frequently associated with syndrome of inappropriate antidiuretic hormone (SIADH) secretion. In this study we investigated the prognostic value of SIADH in Chinese patients with SCLC. METHODS:We prospectively studied a total of 385 patients with SCLC diagnosed in ou...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2015.12.006
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:Acute myocardial infarction (AMI) is a leading cause of death in Mexico. Atherogenic lipid profile is a key component in AMI. Thus, it is imperative to find drug therapies able to reduce atherogenic lipids in AMI patients and prevent subsequent myocardial infarctions. AIM OF THE STUDY:To investigate the eff...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2019.08.002
更新日期：2019-05-01 00:00:00
abstract：:Two hundred fifty women with hirsutism were studied, with a mean age of 25.5 years (ranging from 13 to 38 years). The evolution of hirsutism varied from 3 months to 13 years, being minimal in 82 patients (33%), mild to 101 (40%), moderate in 56 (23%) and severe in the remaining 11 women (4%). Polycystic ovary syndrome...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：
更新日期：1994-10-01 00:00:00
abstract：BACKGROUND:Selenoproteins S (SELS or VIMP) may regulate cytokine production, and thus play a key role in the control of the inflammatory response. METHODS:This study consisted of 136 Iranian patients with cardiovascular disease (65 MetS-affected and 71 MetS un-affected individuals) in the selengene study. Expression o...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2020.05.005
更新日期：2020-08-01 00:00:00
abstract：AIMS:To explore the effect of salvianolic acid B (Sal B) on regulation of SIRT3/FOXO1 signaling pathway in rats with non-alcoholic steatohepatitis (NASH). METHODS:Sixty Sprague Dawley (SD) rats were randomly divided into control, model and treatment groups. After 12 weeks of successful model establishment with high fa...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2017.11.016
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:It remains unclear whether the activation of kappa-opioid receptors has strong hypotensive effects under hypertensive condition, and the underlying mechanisms have not yet been investigated. Therefore, the present study is designed to use spontaneously hypertensive rats (SHR) to investigate the effects of a ...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2007.04.009
更新日期：2007-10-01 00:00:00
abstract：:A definitive single hypothesis about HIV pathogenesis is still lacking in specialized literature. Rather, a picture of the extreme complexity in AIDS causality ensues from the extensive information available. This article contains an outline of the most relevant data on the subject of AIDS pathogenesis, organized into...
journal_title：Archives of medical research
pub_type： 杂志文章,评审
doi：
更新日期：1996-07-01 00:00:00
abstract：:Implantation is a complex spatio-temporal interaction between the genotypically different embryo and the mother. Success of this event requires the synchronization of development and effective biochemical communications from both sides. Chorionic gonadotropin (CG), which is a major embryonic signal in the primate, is ...
journal_title：Archives of medical research
pub_type： 杂志文章,评审
doi：10.1016/s0188-4409(01)00330-7
更新日期：2001-11-01 00:00:00
abstract：:Familial isolated glucocorticoid deficiency is a form of potentially lethal hereditary unresponsiveness to ACTH that manifests as primary adrenal insufficiency, usually without mineralocorticoid deficiency. Affected children commonly present with hyperpigmentation, recurrent hypoglycemia, chronic asthenia and failure ...
journal_title：Archives of medical research
pub_type： 杂志文章,评审
doi：10.1016/s0188-0128(99)00057-3
更新日期：1999-11-01 00:00:00
abstract：:Several studies on biotin intestinal transport in the hamster have shown a biotin-specific carrier, but there are conflicting reports on whether it is transported actively, or by facilitated diffusion and on its Na+ dependence. We have studied it for the first time using brush-border membrane vesicles (BBMV), with con...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：
更新日期：1993-07-01 00:00:00
abstract：:In this report we show the chromosomal changes seen in a group of 303 Mexican patients with de novo Acute Myeloblastic Leukemia (AML). Two hundred forty-two patients were diagnosed and treated at two hospitals affiliated with the Instituto Mexicano del Seguro Social (IMSS). These are the Centro Medico Nacional Siglo X...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：
更新日期：1997-07-01 00:00:00
abstract：BACKGROUND AND AIMS:This study was designed to identify susceptibility to insulin resistance and the association of serum resistin and adiponectin with insulin resistance in patients with Behçet's disease (BD). Also, we identify risk determinants for insulin resistance in BD patients. METHODS:The study population cons...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2010.05.008
更新日期：2010-05-01 00:00:00
abstract：BACKGROUND:Pyruvate kinase isozymes in human breast tumor tissue were compared in this study with normal human breast tissue. Two forms of pyruvate kinase present in normal and tumor human breast were purified by ammonium sulfate precipitation, dialysis, gel filtration, ion exchange, and affinity chromatography. Molecu...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/S0188-4409(03)00054-7
更新日期：2003-07-01 00:00:00
abstract：:Scorpion venom contains different types of peptides toxic to a variety of organisms whose molecular targets have been described as mainly ion-channels of excitable cells where they cause impairment of function. Based on mouse, cricket, and crustacean bioassays, specific toxins for each group of animals have been found...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/s0188-4409(02)00370-3
更新日期：2002-07-01 00:00:00
abstract：BACKGROUND AND AIMS:Streptococcus pneumoniae constitutes one of the main causes of sepsis, bacteremia and meningitis (pneumococcal invasive disease - PID), and pneumonia in infants and small children. Antipneumococcal vaccination in Mexico is expected to be a useful strategy to reduce morbimortality due to this cause. ...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2012.12.005
更新日期：2013-02-01 00:00:00
abstract：:Policosanol, a defined mixture of high molecular weight aliphatic alcohol isolated and purified from sugar cane (Saccharum officinarum, L) wax is a new cholesterol-lowering agent effective in experimental models, healthy volunteers, and patients with type II hypercholesterolemia. Also, policosanol prevents the onset o...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：
更新日期：1997-10-01 00:00:00
abstract：BACKGROUND AND AIMS:Although sporadic cases of cancer in patients with fragile X syndrome (FXS) have been reported, extensive studies carried out in Denmark and Finland concluded that cancer incidence in these patients is lower than in the general population. On the other hand, the FMR1 protein, which is involved in th...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2010.03.001
更新日期：2010-02-01 00:00:00
abstract：BACKGROUND AND AIMS:Previously, TP53 codon 72 polymorphisms have been implicated as risk factors for various cancers. Several studies have been conducted on the association of TP53 codon 72 polymorphisms with susceptibility to nasopharyngeal carcinoma (NPC) and have yielded inconclusive results. The aim of the present ...
journal_title：Archives of medical research
pub_type： 杂志文章,meta分析
doi：10.1016/j.arcmed.2009.03.006
更新日期：2009-05-01 00:00:00
abstract：BACKGROUND:PCI is an expensive procedure in our population and it implies a huge cost for the institutions and National Health Service. AIM OF THE STUDY:The main objective was to evaluate the technical and biological success of two stents designed in Mexico. METHODS:Ten York pigs, 4-6 months of age, underwent implant...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：10.1016/j.arcmed.2020.03.016
更新日期：2020-07-01 00:00:00
abstract：:It is currently accepted that the red blood cell indices (MCV, MCH and MCHC) are the same in general care hospital populations throughout the world. The aim of the study was to explore whether the internationally accepted values for red cell indices are the same in a hospital located in Mexico City at 2240 meters abov...
journal_title：Archives of medical research
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
