Synoviorthesis in young patients with hemophilia and inhibitory antibodies.

Abstract:

:In five patients under the age of 15 with hemophilia and inhibitors, due to frequent joint bleedings, 13 joints were treated with synoviorthesis (intra-articular injection of radioactive gold). The patients received high doses of factor VIII/IX for 2-4 days or were treated simultaneously with tolerance induction according to the Malmö protocol. Of the 13 joints treated, a bleeding-free interval of more than 6 months was obtained in nine of which six remained free from bleedings for more than a year. Ease of performance, the limited requirements of pre- and postoperative care, and a definite decrease in the joint bleeding frequency render synoviorthesis well suited for use in hemophiliacs with inhibitors who are otherwise difficult to treat.

journal_name

Pediatr Hematol Oncol

authors

Löfqvist T,Petersson C

doi

10.3109/08880019209018332

subject

Has Abstract

pub_date

1992-04-01 00:00:00

pages

167-70

issue

2

eissn

0888-0018

issn

1521-0669

journal_volume

9

pub_type

杂志文章
  • Nesiritide in a pediatric oncology patient with renal insufficiency and myocardial dysfunction following septic shock.

    abstract::Nesiritide is a recombinant formulation of B-type natriuretic peptide used most commonly in the treatment of adults with decompensated congestive heart failure. The physiologic effects of BNP include natriuresis, diuresis, and smooth muscle relaxation. These physiologic effects result in its beneficial therapeutic eff...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880010590935248

    authors: Wheeler AD,Tobias JD

    更新日期:2005-06-01 00:00:00

  • Spontaneous remission of acute lymphoblastic leukemia with mediastinal mass.

    abstract::Spontaneous remission/regression of cancer is defined as partial or complete disappearance of malignant disease temporarily or permanently in the absence of medical treatment. This event is named as spontaneous regression for solid tumors and spontaneous remission for leukemia. The authors report the case of a girl ag...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880010801938132

    authors: Yoruk A,Erguven M,Celiker E,Aki H,Timur C,Yuksel E,Ozkan H

    更新日期:2008-04-01 00:00:00

  • Low vitamin D levels are associated with both iron deficiency and anemia in children and adolescents.

    abstract:BACKGROUND:We aimed to examine the association between vitamin D deficiency and anemia in a nationally representative sample of Korean children and adolescents. METHODS:Cross-sectional data on 2526 children and adolescents aged 10-20 years from the Korea National Health and Nutrition Examination Survey-V (2010-2012) w...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章,多中心研究

    doi:10.3109/08880018.2014.983623

    authors: Lee JA,Hwang JS,Hwang IT,Kim DH,Seo JH,Lim JS

    更新日期:2015-03-01 00:00:00

  • Euthyroid sick syndrome in children with Hodgkin disease.

    abstract::Euthyroid sick syndrome is related to profound changes in thyroid metabolism induced by nonthyroidal diseases. To determine whether children with newly diagnosed Hodgkin disease might present thyroid abnormalities and to establish their predictive value, the authors performed regular thyroid function testing. Seven ch...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880010151114886

    authors: Mohn A,Di Marzio A,Cerruto M,Angrilli F,Fioritoni C,Chiarelli F

    更新日期:2001-04-01 00:00:00

  • Isolated relapse of acute lymphoblastic leukemia in the breast of a young female.

    abstract::A 20-year-old female developed a relapse of B-precursor acute lymphoblastic leukemia (ALL) as a mass in her left breast after 6 years of maintained continuous complete remission. No leukemic lesions were identified in other sites such as the bone marrow or cerebrospinal fluid. The relapsed leukemic cells in the breast...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880010802258399

    authors: Todo K,Morimoto A,Osone S,Nukina S,Ohtsuka T,Ishida H,Yoshihara T,Todo S

    更新日期:2008-09-01 00:00:00

  • Two CD34+ stem cells from umbilical cord blood enrichment methods.

    abstract::The authors describe the relation between clamping time and blood volume collected, and two enrichment systems of CD34+ stem cells from umbilical cord blood, to determine an excellent recovery with high proliferate ability and bone marrow reconstitution. After an obstetrician-based cord blood collection, the purificat...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880010252899406

    authors: Pafumi C,Bosco P,Cavallaro A,Farina M,Leonardi I,Pernicone G,Bandiera S,Russo A,Giardina P,Chiarenza M,Calogero AE

    更新日期:2002-06-01 00:00:00

  • Angioimmunoblastic lymphadenopathy with dysproteinemia: report of a case in infancy with review of literature.

    abstract::A case of angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) in infancy is reported. The disease had a mild onset with generalized lymphadenopathy, hepatosplenomegaly, thrombocytopenia, polyclonal hypergammaglobulinemia, and T-cell deficiency. The AILD course lasted more than 100 months, alternating clinica...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章,评审

    doi:10.3109/08880018909014579

    authors: de Terlizzi M,Toma MG,Santostasi T,Colella R,Ceci A,De Benedictis G

    更新日期:1989-01-01 00:00:00

  • Ondansetron and tropisetron in the control of nausea and vomiting in children receiving combined cancer chemotherapy.

    abstract::Ondansetron (Zofron, Glaxo) and tropisetron (Navoban, Sandoz) are selective serotonin (5HT3) antagonists that have proven very effective in the prevention of vomiting and nausea in adults and children receiving cancer chemotherapy. This study compared the efficacy of the two agents in the prevention of vomiting and na...

    journal_title:Pediatric hematology and oncology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/088800199277425

    authors: Stiakaki E,Savvas S,Lydaki E,Bolonaki I,Kouvidi E,Dimitriou H,Kambourakis A,Kalmanti M

    更新日期:1999-03-01 00:00:00

  • Spontaneous acute cerebral hematoma in a child with factor XIII deficiency.

    abstract::Factor XIII deficiency is a very rare bleeding disorder. We report here on the clinical outcome of a young child with intracranial bleeding due to factor XIII deficiency. Clinicians should bear in mind that severe factor XIII deficiency is associated with a significant risk of unexpected intracranial hemorrhage (ICH)....

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.3109/08880018.2013.798059

    authors: Bay A,Sirikci A,Dogan A,Leblebisatan G,Yilmaz F

    更新日期:2013-11-01 00:00:00

  • Complications of β-thalassemia intermedia in Iran during 1996-2010 (single-center study).

    abstract::Patients with thalassemia intermedia (TI) experience many complications, of which the incidence varies greatly among cases. Considering the high prevalence of thalassemia in Iran, the study was carried out to determine the frequency of TI complications in Iranian patients and to find possible risk factors for each of ...

    journal_title:Pediatric hematology and oncology

    pub_type: 临床试验,杂志文章

    doi:10.3109/08880018.2011.572144

    authors: Rafsanjani KA,Mafi N,Tafreshi RI

    更新日期:2011-09-01 00:00:00

  • Endocrinopathies in Turkish children with Beta thalassemia major: results from a single center study.

    abstract::The endocrinological complications in β-thalassemia major patients do affect the life quality to a large extend. In this study, the endocrinological complications of 47 β-thalassemia patients, who have been followed-up at our hospital's pediatric hematology department, were evaluated. Out of β-thalassemia major cases ...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.3109/08880018.2014.898724

    authors: Isik P,Yarali N,Tavil B,Demirel F,Karacam GB,Sac RU,Fettah A,Ozkasap S,Kara A,Tunc B

    更新日期:2014-10-01 00:00:00

  • Hyponatremia and renal sodium wasting in patients receiving cisplatinum.

    abstract::Three children with malignant solid tumors developed hyponatremia with renal sodium wasting associated with other signs of tubular dysfunction, such as hypokalemia or hypomagnesemia, a few days after cis-diammine dichloroplatinum (CDDP) administration. The normalization of serum electrolyte disturbances was obtained w...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.3109/08880018709141287

    authors: Vassal G,Rubie H,Kalifa C,Hartmann O,Lemerle J

    更新日期:1987-01-01 00:00:00

  • Relapse of primitive mediastinal lymphoma as a myeloid mass following beam autologous transplant and subsequent refractoriness to matched unrelated umbilical cord blood allograft.

    abstract::Outlining the treatment for an unclassifiable lymphoid malignancy is often difficult. A highly undifferentiated lymphomatous mass that relapsed in spite of intense chemotherapy and autologous transplant is reported. At relapse, there was differentiation into myeloid lineage. Though remission was achieved with AML-type...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880010902754883

    authors: Anoop P,Lancaster DL,Ethell ME,Potter MN,Wotherspoon A

    更新日期:2009-03-01 00:00:00

  • Neutrophil apoptosis in patients with beta-thalassemia major.

    abstract::Increased susceptibility to infection is reported in patients with beta-thalassemia major due to toxic effect of iron on neutrophil functions and reticuloendothelial system dysfunction. This study investigated the association between the neutrophil apoptosis and frequency of infection episodes, desferrioxamine treatme...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/713842280

    authors: Oren H,Sahin B,Irken G,Ateş H,Duman M,Yilmaz S,Türker M,Atabay B,Yaprak I

    更新日期:2003-04-01 00:00:00

  • Red blood cell distribution width is not a reliable biomarker for low iron stores in children with cystic fibrosis.

    abstract::Low iron stores in children, absolute iron deficiency (AID), can lead to impaired neurodevelopment and requires iron therapy. In the presence of infection/inflammation, like in cystic fibrosis (CF), serum ferritin (SF) is not a reliable biomarker for AID. Red blood cell distribution width (RDW) is a promising alternat...

    journal_title:Pediatric hematology and oncology

    pub_type: 临床试验,杂志文章

    doi:10.1080/08880018.2016.1268226

    authors: Akkermans MD,Uijterschout L,Nuijsink M,Hendriks DM,van Goudoever JB,Brus F

    更新日期:2017-02-01 00:00:00

  • Nutritional vitamin B12 deficiency in infancy: three case reports and a review of the literature.

    abstract::Three cases of vitamin B12 deficiency that occurred during infancy are presented. These cases appeared to be the result of pre-existing maternal deficiency. All three infants demonstrated evidence of neurodevelopmental delay at presentation, and one had sustained loss of milestones and developed involuntary motor move...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章,评审

    doi:10.3109/08880018909034282

    authors: Doyle JJ,Langevin AM,Zipursky A

    更新日期:1989-01-01 00:00:00

  • Pregnancy in patients treated for beta thalassemia major in two centers (Ali Asghar Children's Hospital and Thalassemia Clinic): outcome for mothers and newborn infants.

    abstract::Beta-thalassemia major is a severe, transfusion-dependent anemia that also causes infertility due to iron deposition to endocrine organs after overtransfusion. Very few pregnancies have been reported among such patients after modern therapies. In this study, 32 women with thalassemia who were admitted to Ali Asghar Ch...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章,多中心研究

    doi:10.1080/08880010500313306

    authors: Ansari S,Azarkeivan A,Tabaroki A

    更新日期:2006-01-01 00:00:00

  • Clinical value of RAG1 expression and IKZF1 deletions in Philadelphia negative pediatric B cell precursor acute lymphoblastic leukemia.

    abstract::This study aimed to address the clinical impact of recombination-activating gene (RAG1) expression and tumor suppressor IKZF1 gene deletions in Philadelphia negative B-cell precursor acute lymphoblastic leukemia (B-ALL) patients. Fifty newly diagnosed pediatric Philadelphia negative B-ALL patients were included in thi...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880018.2020.1767739

    authors: Aref S,Khaled N,Menshawy NE,Sabry M,Agder MA

    更新日期:2020-08-01 00:00:00

  • Spinal cord compression: a review of 70 pediatric patients.

    abstract::The authors report their experience with 70 pediatric patients with spinal cord compression (SCC) due to malignancies identified among 898 patients with solid tumors. An extradural tumor was the most frequent cause of SCC (71%); 54% of these were soft tissue sarcomas and neuroblastoma. Most intradural tumors (70%) wer...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章,评审

    doi:

    authors: Pollono D,Tomarchia S,Drut R,Ibañez O,Ferreyra M,Cédola J

    更新日期:2003-09-01 00:00:00

  • Olfactory neuroblastoma in children: results of multimodality treatment in 2 patients.

    abstract::Olfactory neuroblastoma, a rare malignancy of the olfactory epithelium, is an uncommon tumor in children. It occurs mostly in older individuals and the treatment strategies are based on the experience with adults. In this report, clinical characteristics and treatment results of 2 patients with olfactory neuroblastoma...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.3109/08880018.2010.514656

    authors: Küpeli S,Yalçin B,Büyükpamukçu M

    更新日期:2011-02-01 00:00:00

  • MRI changes in the "normal" pineal gland following chemotherapy for suprasellar germ cell tumors.

    abstract::Primary CNS germ cell tumors (GCT) arise in the suprasellar and pineal regions. Suprasellar GCT may remain radiographically occult during the early symptomatic period. Although theoretically possible, it is more difficult to identify presymptomatic disease in the pineal region. Given the sensitivity of GCT to cytotoxi...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880010701665777

    authors: MacDonald SM,Desai N,Heller G,Rolnitzky L,Allen JC

    更新日期:2008-01-01 00:00:00

  • Changing pattern of treatment policies invalidates the use of C-reactive protein level and hyponatremia as indicators of sepsis in children with malignancies.

    abstract::We evaluated serum C-reactive protein (CRP) level and serum sodium concentration as early indicators of bacteremia in neutropenic children in two different series in 1983-1984 (49 bacteremias) and 1989-1990 (29 bacteremias). During the earlier period, the goal was to avoid unnecessary antimicrobial therapy. Currently ...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.3109/08880019209016609

    authors: Riikonen P,Saarinen UM,Perkkiö M,Hovi L,Siimes MA

    更新日期:1992-10-01 00:00:00

  • Immune thrombocytopenic purpura in childhood in Norway: a prospective, population-based registration.

    abstract::A prospective, population-based registration of children with immune thrombocytopenic purpura (ITP) was performed in Norway in 1996 and 1997. Ninety-two cases were identified, indicating an incidence of 5.3 per 100,000 children under 15 years. The sex ratio (female/male) was 1.2/1. Fifty-six percent presented with cut...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880010050122816

    authors: Zeller B,Helgestad J,Hellebostad M,Kolmannskog S,Nystad T,Stensvold K,Wesenberg F

    更新日期:2000-10-01 00:00:00

  • Growth hormone deficiency following radiotherapy for orbital and parameningeal sarcomas.

    abstract::Growth hormone deficiency (GHD) is a recognized late effect of successful treatment of tumors requiring cranial irradiation. Growth after treatment was assessed in 16 patients with sarcomas of the orbital and parameningeal regions. Median age at diagnosis was 6.35 years and median follow-up was 7.2 years. Treatment co...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/088800199277560

    authors: Goddard AG,Harris SJ,Plowman PN,Savage MO,Kingston JE

    更新日期:1999-01-01 00:00:00

  • Acute megakaryoblastic leukemia (excluding Down syndrome) remains an acute myeloid subgroup with inferior outcome in the French ELAM02 trial.

    abstract::We report the outcome of 27 children with de novo acute megakaryoblastic leukemia (AMKL) (excluding Down syndrome) enrolled in the French multicenter prospective study ELAM02 (2005-2011). There was no difference in gender, initial leukocyte count, CNS involvement, and complete remission rate (88.9%), as compared to ot...

    journal_title:Pediatric hematology and oncology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1080/08880018.2017.1414905

    authors: Teyssier AC,Lapillonne H,Pasquet M,Ballerini P,Baruchel A,Ducassou S,Fenneteau O,Petit A,Cuccuini W,Ragu C,Preudhomme C,Mercher T,Sirvent N,Leverger G

    更新日期:2017-11-01 00:00:00

  • Characterization of the coagulation profile in children with liver disease and extrahepatic portal vein obstruction or shunt.

    abstract:INTRODUCTION:Chronic liver disease causes a disruption of procoagulant and anticoagulant factors, resulting in a fragile state, prone to increased rates of both bleeding and thrombosis. Currently, there is limited literature describing the changes observed in pediatric liver disease and extrahepatic portal vein obstruc...

    journal_title:Pediatric hematology and oncology

    pub_type: 临床试验,杂志文章

    doi:10.1080/08880018.2017.1313919

    authors: Beattie W,Magnusson M,Hardikar W,Monagle P,Ignjatovic V

    更新日期:2017-03-01 00:00:00

  • Pediatric Burkitt's lymphoma and diffuse B-cell lymphoma: are surveillance scans required?

    abstract::Outcomes in pediatric B-Non-Hodgkin Lymphoma (B NHL) have improved with intensive chemotherapy protocols, with long-term survival now over 80%. However, long-term adverse effects of therapy and poor outcomes for patients who relapse remain challenges. In this study, we aimed to evaluate the potential risks and benefit...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.3109/08880018.2013.834400

    authors: Eissa HM,Allen CE,Kamdar K,Simko S,Goradia P,Dreyer Z,Steuber P,McClain KL,Guillerman RP,Bollard CM

    更新日期:2014-04-01 00:00:00

  • Clear cell sarcoma: a dilemma on pathological staging and clinical management.

    abstract::Clear cell sarcoma of the kidney (CCSK) has been classified as high risk tumour in the previous UK and international Wilms tumor studies. The current Society of Paediatric Oncology (SIOP) trial, UK version, advocates chemotherapy including doxorubicin prior to nephrectomy. Pathological staging and histology of the res...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880010590921685

    authors: Ng A,Jenkinson H,Morland B,Grundy R

    更新日期:2005-04-01 00:00:00

  • α-Thalassemia frequency and mutations in children with hypochromic microcytic anemias and relation with β-thalassemia, iron deficiency anemia.

    abstract::The majority of the anemias during childhood are hypochromic and microcytic. The aim of the present study was to determine the status of α-thalassemia mutations and its association with other etiologies, such as iron deficiency anemia (IDA) and β-thalassemia trait, that are frequently seen hypochromic microcytic anemi...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.3109/08880018.2012.661831

    authors: Gulen H,Hanimeli O,Karaca O,Taneli F

    更新日期:2012-04-01 00:00:00

  • Practice guidelines in pediatric hematooncology: implementation and survey. A possible way for medical quality assurance.

    abstract::The Hungarian Pediatric Oncology Working Group intended to change the practice of prescribing diagnostic tests as well as to examine the possibility of introducing indicators about the time factors of medical care. A nationwide accepted protocol was established for these tests. The examined time factors were the lengt...

    journal_title:Pediatric hematology and oncology

    pub_type: 杂志文章

    doi:10.1080/08880010050211394

    authors: Pásztélyi Z,Schuler D,Czvenits E

    更新日期:2000-12-01 00:00:00