Antenatal factors associated with significant birth weight discordancy in twin gestations.

Abstract:

OBJECTIVE:The purpose of this study was to evaluate factors that are associated with significant birth weight discordancy. STUDY DESIGN:As a part of an ongoing collaborative study of twins, maternal and fetal data were obtained from the medical records of twin gestations at eight medical centers. The study population was divided into groups by difference in birth weight discordancy (>or=20%, >or=25%, and >or=30%) RESULTS:Severe birth weight discordancy was associated with fetal growth deceleration by 20 to 28 weeks (adjusted odds ratio, 4.90; 95% CI, 3.15-7.64) and between 28 weeks to birth (adjusted odds ratio, 3.48; 95% CI, 1.72-7.06). Antenatal bleeding (adjusted odds ratio, 1.86; 95% CI, 1.08-3.21), preeclampsia (adjusted odds ratio, 1.70, 95% CI, 1.21-2.41), and monochorionicity (adjusted odds ratio, 2.35, 95% CI, 11.71-3.23) were also associated with birth weight discordancy. CONCLUSION:These data demonstrate the importance of the early diagnosis of placental chorionicity, because monochorionicity is associated with a 2-fold increase in birth weight discordancy in twin gestations.

journal_name

Am J Obstet Gynecol

authors

González-Quintero VH,Luke B,O'sullivan MJ,Misiunas R,Anderson E,Nugent C,Witter F,Mauldin J,Newman R,D'alton M,Grainger D,Saade G,Hankins G,Macones G

doi

10.1067/s0002-9378(03)00658-6

subject

Has Abstract

pub_date

2003-09-01 00:00:00

pages

813-7

issue

3

eissn

0002-9378

issn

1097-6868

pii

S0002937803006586

journal_volume

189

pub_type

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