Structural characteristics of heparan sulfates with varying sulfate contents.

Abstract:

:Structural properties of heparan sulfate preparations from hog mucosa and beef lung sources were obtained by application of Smith degradation and nitrous acid reactions. Products formed by these reactions indicated that most of the iduronic acid present in these mucopolysaccharides is ester sulfated, whereas N-sulfated glucosamine residues are ester sulfated much less frequently. Repeating units with sulfated iduronic acid found to occur almost entirely in single sequences. Futhermore, the iduronic acid moieties may be bound to either N-acetylated or N-sulfated glucosamine units, with these occuring at either end of the uronic acid unit.

journal_name

Biochemistry

journal_title

Biochemistry

authors

Cifonelli JA,King JA

doi

10.1021/bi00629a014

subject

Has Abstract

pub_date

1977-05-17 00:00:00

pages

2137-41

issue

10

eissn

0006-2960

issn

1520-4995

journal_volume

16

pub_type

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