Search for a retrovirus in multiple sclerosis by enzymatic amplification of DNA from brain capillaries, brain tissue and mononuclear cells from peripheral blood.

abstract：:Three patients are presented who developed conduction aphasia after a small infarction almost exclusively confined to the arcuate fasciculus. All of them were diagnosed as conduction aphasia within a week after the stroke and showed a rapid amelioration. On the basis of the 3 patients and conduction aphasics in the li...

journal_title：Acta neurologica Scandinavica

authors： Tanabe H,Sawada T,Inoue N,Ogawa M,Kuriyama Y,Shiraishi J

更新日期：1987-12-01 00:00:00

abstract：OBJECTIVES:The differential diagnosis of patients with idiopathic parkinsonism is difficult, especially early in the course of the disease. External anal sphincter electromyography (EAS-EMG) has been reported to be of value in the differential diagnosis between Parkinson's disease (PD) and multiple system atrophy (MSA)...

journal_title：Acta neurologica Scandinavica

authors： Linder J,Libelius R,Nordh E,Holmberg B,Stenlund H,Forsgren L

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy of buccally absorbed prochlorperazine (BAP) to intravenous prochlorperazine (IVP) for the abortive treatment of migraine headaches. METHODS:Randomized double-blind trial. Eighty subjects aged 18-65 presenting with migraines to the ED of a safety-net, urban hospital. Subjects were rand...

journal_title：Acta neurologica Scandinavica

authors： Fernando T,Lumanauw DD,Youn S,Shimada M,Yadav K,Chappell B,Horeczko T,Tanen DA

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVES:To study the changes in the burden of informal caregivers of patients with disorders of consciousness (DOC) over time. MATERIALS AND METHODS:Short Form-12, Family Strain Questionnaire, Beck Depression Inventory and Coping Orientations to Problem Experiences were administered. RESULTS:Data collected on 216 ...

journal_title：Acta neurologica Scandinavica

authors： Covelli V,Sattin D,Giovannetti AM,Scaratti C,Willems M,Leonardi M

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:We aimed to study knee proprioception and somatosensory evoked potentials (SEPs) to stimulation of the common peroneal nerve (CPN) in 7 patients with lesion of the anterior cruciate ligament (ACL) before and after ACL reconstruction. MATERIALS AND METHODS:We recorded the spinal N14 and scalp P27 potentials ...

journal_title：Acta neurologica Scandinavica

authors： Valeriani M,Restuccia D,Di Lazzaro V,Franceschi F,Fabbriciani C,Tonali P

更新日期：1999-05-01 00:00:00

abstract：:By a rapid PCR-based method to assess the 8344 mtDNA mutation associated with MERRF disease, we have studied DNA from blood samples of 10 individuals belonging to a family spanning four generations in which one patient showed the complete MERRF phenotype, three other members were less severely affected, while the rema...

journal_title：Acta neurologica Scandinavica

authors： Piccolo G,Focher F,Verri A,Spadari S,Banfi P,Gerosa E,Mazzarello P

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:There has been a long-standing interest in the possible role of the hippocampus in autism and both postmortem brain and neuroimaging studies have documented varying abnormalities in this limbic system structure. AIMS:This study investigates the density of subsets of hippocampal interneurons, immunostained w...

journal_title：Acta neurologica Scandinavica

authors： Lawrence YA,Kemper TL,Bauman ML,Blatt GJ

更新日期：2010-02-01 00:00:00

abstract：:The clinical indications for temporal artery biopsy were explored using clinical decision analysis. The analysis indicated that biopsy is most useful in patients with a high likelihood of steroid side effects. It is nearly always useful when the pre-biopsy likelihood of temporal arteritis is low, but loses its value w...

journal_title：Acta neurologica Scandinavica

authors： Nadeau SE

更新日期：1988-08-01 00:00:00

abstract：:IgG subgroups (IgG1, IgG2, IgG3, IgG4) were determined by radioimmunoassay (RIA) in cerebrospinal fluid (CSF) of controls, multiple sclerosis (MS), infectious diseases (ID) and other neurological diseases (OND). The proportion of IgG1 in the total IgG subgroup concentration was significantly higher in the MS group com...

journal_title：Acta neurologica Scandinavica

authors： Eickhoff K,Kaschka W,Skvaril F,Theilkaes L,Heipertz R

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine whether reactivation of Epstein-Barr (EBV) or activation of the anti-EBV immune response correlates with MS disease activity on MR imaging. METHODS:Subjects with early, active relapsing-remitting MS were studied for 16 weeks with blood and saliva samples collected...

journal_title：Acta neurologica Scandinavica

authors： Latham LB,Lee MJ,Lincoln JA,Ji N,Forsthuber TG,Lindsey JW

更新日期：2016-01-01 00:00:00

abstract：:Previous reports concerning the treatment of symptoms deriving from prolapsed lumbar disc with systemic administration of the potent steroid dexamethasone, have shown favourable results. The present clinical study includes 39 patients with symptoms of prolapsed lumbar disc, treated in a controlled double-blind investi...

journal_title：Acta neurologica Scandinavica

authors： Hedeboe J,Buhl M,Ramsing P

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVE:White matter (WM) integrity of Spinocerebellar ataxia 2 (SCA2) is poorly understood, more so in the early stages of SCA2. In this study, we evaluated the microstructural integrity of the WM tracts with an emphasis on the nature of in vivo pathological involvement in early SCA2. MATERIALS AND METHODS:We evalu...

journal_title：Acta neurologica Scandinavica

authors： Stezin A,Bhardwaj S,Khokhar S,Hegde S,Jain S,Bharath RD,Saini J,Pal PK

更新日期：2020-10-08 00:00:00

abstract：OBJECTIVES:To assess the effectiveness and safety/tolerability of eslicarbazepine acetate (ESL) in patients included in the Euro-Esli study who had focal seizures associated with post-stroke epilepsy (PSE). MATERIALS AND METHODS:Euro-Esli was a pooled analysis of 14 European clinical practice studies. Effectiveness as...

journal_title：Acta neurologica Scandinavica

authors： Sales F,Chaves J,McMurray R,Loureiro R,Fernandes H,Villanueva V

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Hereditary haemorrhagic telangiectasia (HHT) is a dominantly inherited disease characterized by a wide variety of clinical manifestations, including pulmonary arteriovenous malformations (PAVMs), which due to paradoxical embolization may cause cerebral abscess. OBJECTIVE:To estimate the risk of cerebral abs...

journal_title：Acta neurologica Scandinavica

authors： Kjeldsen AD,Tørring PM,Nissen H,Andersen PE

更新日期：2014-03-01 00:00:00

abstract：:The cerebrovascular response to arterial hypoxia was studied during blockade of the vascular dopamine receptors and during alpha-adrenergic receptor stimulation and blockade in anaesthetized dogs. Dopamine receptor blockade with pimozide or haloperidol invariably decreased the degree of hypoxic vasodilatation in the ...

journal_title：Acta neurologica Scandinavica

authors： Ekström-Jodal B,Elfverson J,von Essen C

更新日期：1978-02-01 00:00:00

abstract：:A model is described in which transient ischemia is induced in rats anaesthetized with N2O:O2 (70:30) by bilateral carotid artery clamping combined with a lowering of mean arterial blood pressure to 50 mm Hg, the latter being achieved by bleeding, or by bleeding supplemented with administration of trimetaphan or phent...

journal_title：Acta neurologica Scandinavica

authors： Smith ML,Bendek G,Dahlgren N,Rosén I,Wieloch T,Siesjö BK

更新日期：1984-06-01 00:00:00

abstract：OBJECTIVES:To measure clinical and immunological parameters in a patient with myasthenia gravis (MG) treated with antibodies against CD25 (basiliximab, Simulect). Patient and methods - Injections of basiliximab were given repeatedly together with cyclosporin A and corticosteroids for 9 months to a patient with severe M...

journal_title：Acta neurologica Scandinavica

authors： Kakoulidou M,Pirskanen-Matell R,Lefvert AK

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:LMNB1-related autosomal dominant leukodystrophy is caused by an overexpression of the protein lamin B1, usually due to a duplication of the LMNB1 gene. Symptoms start in 5th to 6th decade. This slowly progressive disease terminates with death. We studied brain glucose metabolism in this disease using 18 F-flu...

journal_title：Acta neurologica Scandinavica

authors： Finnsson J,Lubberink M,Savitcheva I,Fällmar D,Melberg A,Kumlien E,Raininko R

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:To investigate the prevalence of G88C, G209A and any other mutation(s) in exons 3 and 4 of the alpha-synuclein gene in Indian patients with Parkinson's disease (PD). METHODS:A total of 169 PD patients comprising 18 familial, 3 juvenile, 48 early onset and 100 sporadic cases were included in this study. Genom...

journal_title：Acta neurologica Scandinavica

authors： Nagar S,Juyal RC,Chaudhary S,Behari M,Gupta M,Rao SN,Thelma BK

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVES:To investigate the frequency of ECG abnormalities suggestive of myocardial ischaemia in patients with severe drug resistant epilepsy and without any indication of previous cardiac disease, assuming that these changes may be of significance for the group of epileptic patients with sudden unexpected death. MA...

journal_title：Acta neurologica Scandinavica

authors： Tigaran S,Rasmussen V,Dam M,Pedersen S,Høgenhaven H,Friberg B

更新日期：1997-08-01 00:00:00

abstract：:We describe eight patients from three families presenting with myoclonus, ataxia, infrequent seizures and minimal intellectual impairment. All were Arabs from different parts of the Arabian peninsula. The new consensus on terminology, genetic and clinical definition of Baltic myoclonus, Ramsay Hunt syndrome and Unverr...

journal_title：Acta neurologica Scandinavica

authors： Shakir RA,Khan RA,al-Zuhair AG

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVE:To clarify how chronic solvent abuse affects cognitive function using magnetic resonance imaging as an index of brain damage. MATERIAL AND METHODS:A total of 25 chronic solvent abusers underwent magnetic resonance imaging with quantitative neurometry and Wechsler Adult Intelligence Scales revised. RESULTS:T...

journal_title：Acta neurologica Scandinavica

authors： Yamanouchi N,Okada S,Kodama K,Sakamoto T,Sekine H,Hirai S,Murakami A,Komatsu N,Sato T

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVES:Studies demonstrating reduced quality of life and psychological well-being in multiple sclerosis (MS) have typically investigated patients within more advanced stages of disease. The aim of the present paper was to evaluate the emotional burden and quality of life of recently diagnosed MS patients and their ...

journal_title：Acta neurologica Scandinavica

authors： Janssens AC,van Doorn PA,de Boer JB,van der Meché FG,Passchier J,Hintzen RQ

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVES:Subjective feelings of memory decline are fairly common among the elderly. The causes of this are heterogeneous, and may be related to both affective and cognitive disorders. We attempted to explore the associations between subjective and cognitive measures. MATERIALS AND METHODS:Healthy subjects were studi...

journal_title：Acta neurologica Scandinavica

authors： Balash Y,Mordechovich M,Shabtai H,Merims D,Giladi N

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVES:Fatigue and apathy are two of the most common and most disabling non-motor symptoms of Parkinson's disease (PD). They have a high coincidence and can often be confused; moreover, their relationship is not fully understood. The aim of our study was to describe the coincidence of apathy with different fatigue ...

journal_title：Acta neurologica Scandinavica

authors： Skorvanek M,Gdovinova Z,Rosenberger J,Saeedian RG,Nagyova I,Groothoff JW,van Dijk JP

更新日期：2015-02-01 00:00:00

abstract：:Brain perfusion was studied interictally with 99mTc-HM-PAO SPECT in 47 adult patients with partial epilepsy and normal brain CT. Epilepsy was classified as secondarily generalized in 24 patients, as complex partial in 17 patients and as simple partial in 6 patients. In 24 patients good seizure control was not achieved...

journal_title：Acta neurologica Scandinavica

authors： Launes J,Iivanainen M,Salmi T,Nikkinen P,Lindroth L,Liewendahl K

更新日期：1992-12-01 00:00:00

abstract：:Adenylate kinase (AK) was determined in a lumbo-cisternal cerebrospinal fluid (CSF) gradient and in CSF from patients with mental deterioration. AK activity was unchanged in the gradient and different from albumin and albumin ratio (alb CSF/albumin serum), a blood-brain barrier marker in the same gradient. No differen...

journal_title：Acta neurologica Scandinavica

authors： Ahlberg J,Blomstrand C,Ronquist G,Wikkelsö C

更新日期：1985-11-01 00:00:00

abstract：OBJECTIVES:Little is known about the frequency of abnormal visually evoked potentials (VEPs) in patients with respiratory chain disorders (RCDs). We thus wanted to investigate the frequency of abnormal VEPs in RCDs, how often VEPs are abnormal despite normal visual acuity, and which of the VEP variables are most often ...

journal_title：Acta neurologica Scandinavica

authors： Finsterer J

更新日期：2001-07-01 00:00:00

abstract：UNLABELLED:Soluble APO-1 (sAPO-1) may prevent apoptosis of lymphocytes induced by activation of the APO-1/Fas receptor. OBJECTIVES:To determine sAPO-1 levels in the serum of multiple sclerosis (MS) patients and controls in order to investigate if abnormal lymphocyte apoptosis occurs in this disease. METHODS:Serum sam...

journal_title：Acta neurologica Scandinavica

authors： Bansil S,Holtz CR,Cook SD,Rohowsky-Kochan C

更新日期：1997-04-01 00:00:00

abstract：:Serum lipids and the cholesterol concentration in the high density lipoprotein (HDL) fraction were measured in epileptic patients taking either carbamazepine or phenytoin as single drug treatment. There was a significant increase in HDL-cholesterol levels in patients taking both phenytoin and carbamazepine. Serum tota...

journal_title：Acta neurologica Scandinavica

authors： O'Neill B,Callaghan N,Stapleton M,Molloy W

更新日期：1982-02-01 00:00:00