Effects of using dexamethasone and placebo in the treatment of prolapsed lumbar disc.

Abstract:

:Previous reports concerning the treatment of symptoms deriving from prolapsed lumbar disc with systemic administration of the potent steroid dexamethasone, have shown favourable results. The present clinical study includes 39 patients with symptoms of prolapsed lumbar disc, treated in a controlled double-blind investigation with dexamethasone or placebo. Twenty patients had provable effect of the treatment, 19 had no effect. Nineteen patients received dexamethasone (13 + effect), 20 received placebo (7 + effect). The groups were fully comparable, and the difference is not statistically significant. During a period of 3 months 50% of the patients who improved by the treatment of either group had recurrences leading to operation. It is concluded that the effect of dexamethasone given intramuscularly does not seem to exceed that of placebo in the treatment of prolapsed lumbar disc.

journal_name

Acta Neurol Scand

authors

Hedeboe J,Buhl M,Ramsing P

doi

10.1111/j.1600-0404.1982.tb03055.x

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

6-10

issue

1

eissn

0001-6314

issn

1600-0404

journal_volume

65

pub_type

临床试验,杂志文章
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  • Isolated seizures in rats do not cause neuronal injury.

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    pub_type: 杂志文章

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    pub_type: 杂志文章

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    pub_type: 杂志文章,评审

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    pub_type: 杂志文章

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1987.tb07928.x

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1995.tb01696.x

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    更新日期:1995-09-01 00:00:00

  • A comprehensive electrophysiological evaluation of phrenic nerve injury related to open-heart surgery.

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1995.tb07000.x

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  • EEG in presenile dementia related to cerebral blood flow and autopsy findings.

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    doi:10.1111/j.1600-0404.1977.tb01414.x

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1982.tb06869.x

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  • Epidemiology of multiple sclerosis in western Poland--a comparison between prevalence rates in 1965 and 1981.

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1985.tb00866.x

    authors: Wender M,Pruchnik-Grabowska D,Hertmanowska H,Kowal P,Zielińska M,Namysł I,Marcinkowski J

    更新日期:1985-08-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:2016-11-01 00:00:00

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    pub_type: 杂志文章

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1999.tb07359.x

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    pub_type: 杂志文章

    doi:10.1111/j.1600-0404.1979.tb02973.x

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    更新日期:1979-10-01 00:00:00

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    pub_type: 临床试验,杂志文章

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    doi:10.1111/j.1600-0404.1981.tb00754.x

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