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Two high molecular mass proteases from sea urchin sperm.

Abstract：

:Two-types of high molecular mass proteases have been purified from sea urchin sperm using DEAE-Sephacel, hydroxylapatite and Superdex 200 column chromatography. Both proteases showed similar hydrolyzing activities toward synthetic peptides, but they differed in the molecular mass and peptide composition. One was probably identical to a proteasome (multicatalytic proteinase), judging from its molecular mass (650 kDa) and polypeptide composition. The other one was composed of several polypeptides with molecular masses ranging from 24 kDa to 125 kDa and its molecular mass was estimated as 950 kDa by gel filtration. These two proteases, however, were closely related to each other. Immunological studies revealed that the 950-kDa protease comprised at least five subunits of the 650-kDa protease.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Inaba K,Akazome Y,Morisawa M

doi

10.1016/0006-291x(92)91784-n

subject

Has Abstract

pub_date

1992-01-31 00:00:00

pages

667-74

issue

2

eissn

0006-291X

issn

1090-2104

pii

0006-291X(92)91784-N

journal_volume

182

pub_type

杂志文章

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