Abstract：
:Proton MR spectroscopy was used to observe long-term post-irradiation metabolic changes in epileptogenic tissue and in the contralateral parts of the brain which are not available with conventional imaging methods. We studied these changes in the temporal lobe in six patients, following radiosurgery on the amygdala and hippocampus. (1)H MR spectroscopy at 1.5 T with short and long echo times (TE=10 and 135 ms) were used together with standard MR imaging sequences (T1-, T2-weighted). The treatment was performed by Leksell Gamma Knife with a dose of 50 Gy to the center and a 50% isodose to the margin of the target, represented by the mean volume of approximately 7.5 ml. Magnetic resonance imaging and MR spectroscopy examinations were performed at least once per year for 3 years. The most significant changes in spectra were observed approximately 1 year after the irradiation when edema in irradiated area was observed and strong signal of lipids was identified. Later, edema and lipid signals disappeared and follow-up was characterized by a decrease of NAA, Cr, and Cho concentrations in the ipsilateral region of the brain to the irradiation (LCModel calculation from voxel of interest 3.8-4.5 ml positioned into the centrum of target volume). The concentration of NAA, Cr, and Cho after radiosurgery was significantly different from control values ( p<0.05) and also from concentrations in the contralateral part of the brain ( p<0.05). In the contralateral part, the concentration of NAA was significantly increased ( p<0.05) (NAA: before treatment 8.81, after treatment 11.33 mM). No radiotoxic changes were observed in the contralateral part of the brain or behind the area of target volume. The MR spectroscopy findings precluded MRI observation and MRS results completed data about the development of radiotoxic changes in the target volume.
journal_name
Eur Radioljournal_title
European radiologyauthors
Hájek M,Dezortová M,Liscák R,Vymazal J,Vladyka Vdoi
10.1007/s00330-002-1723-5subject
Has Abstractpub_date
2003-05-01 00:00:00pages
994-1000issue
5eissn
0938-7994issn
1432-1084journal_volume
13pub_type
杂志文章abstract：:Our objective was to follow-up patients in whom scheduled MR-guided vacuum biopsies for suspicious lesions were aborted due to absent enhancement of contrast medium. Thirty-seven of 291 scheduled MR-guided vacuum biopsies were aborted. Six cases were lost to follow-up. Two could be unequivocally identified and were ne...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-002-1713-7
更新日期：2003-02-01 00:00:00
abstract：OBJECTIVE:This retrospective study aims to assess the accuracy of two-phase computed tomography (CT) and transoesophageal echocardiography (TEE) for the detection of left atrial (LA) thrombus in patients with mitral stenosis (MS) and atrial fibrillation (AF), by using intraoperative findings as the reference standard. ...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-013-2944-5
更新日期：2013-11-01 00:00:00
abstract：BACKGROUND:Hypersensitivity pneumonitis (HP) has a variable clinical course. Modelling of quantitative CALIPER-derived CT data can identify distinct disease phenotypes. Mortality prediction using CALIPER analysis was compared to the interstitial lung disease gender, age, physiology (ILD-GAP) outcome model. METHODS:CAL...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-016-4697-4
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVES:To determine whether dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) can differentiate benign from malignant cartilage tumours compared to standard MRI. To investigate whether a cutoff value could be determined to differentiate enchondroma from low-grade chondrosarcoma (CS) more accurately. ...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-013-2913-z
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVE:To assess the role of colour Doppler flow imaging (CDFI) in the diagnosis and management of lacrimal fossa lesions. METHODS:Institutional ethical committee approval was obtained. Fifty-one patients with 62 lacrimal fossa lesions were retrospectively included from 2003-2015. All patients underwent conventiona...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-016-4438-8
更新日期：2017-02-01 00:00:00
abstract：:Several excellent imaging modalities are available for studying the great vessels of the chest noninvasively. Besides computed tomography (CT), magnetic resonance imaging (MRI) and echocardiography (in particular the transesophageal approach) can accurately depict abnormalities of the thoracic vasculature, and are a v...
journal_title：European radiology
pub_type： 杂志文章,评审
doi：10.1007/s003300050516
更新日期：1998-01-01 00:00:00
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journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-015-4192-3
更新日期：2016-10-01 00:00:00
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journal_title：European radiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00330-018-5887-z
更新日期：2019-06-01 00:00:00
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journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/BF00180601
更新日期：1996-01-01 00:00:00
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journal_title：European radiology
pub_type： 杂志文章
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更新日期：2017-07-01 00:00:00
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pub_type： 杂志文章
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更新日期：2021-02-01 00:00:00
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journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-014-3277-8
更新日期：2014-10-01 00:00:00
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journal_title：European radiology
pub_type： 杂志文章,评审
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更新日期：2020-01-01 00:00:00
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journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-005-2849-z
更新日期：2006-02-01 00:00:00
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journal_title：European radiology
pub_type： 杂志文章
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更新日期：2005-05-01 00:00:00
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journal_title：European radiology
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00330-018-5713-7
更新日期：2019-03-01 00:00:00
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journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-020-07020-3
更新日期：2020-12-01 00:00:00
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journal_title：European radiology
pub_type： 杂志文章,评审
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更新日期：2019-03-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/s00330-005-2731-z
更新日期：2005-08-01 00:00:00
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journal_title：European radiology
pub_type： 杂志文章
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更新日期：2013-01-01 00:00:00
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journal_title：European radiology
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journal_title：European radiology
pub_type： 杂志文章,meta分析
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更新日期：2020-01-01 00:00:00
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journal_title：European radiology
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更新日期：2013-03-01 00:00:00
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journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-019-06335-0
更新日期：2020-01-01 00:00:00
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journal_title：European radiology
pub_type： 杂志文章,meta分析,评审
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更新日期：2018-06-01 00:00:00
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journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s00330-010-1903-7
更新日期：2011-01-01 00:00:00
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journal_title：European radiology
pub_type： 杂志文章
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更新日期：2020-09-28 00:00:00
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journal_title：European radiology
pub_type： 杂志文章,多中心研究
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更新日期：2003-07-01 00:00:00
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journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s003300050477
更新日期：1998-01-01 00:00:00
abstract：:We report the CT and pathological findings of an intra-abdominal desmoplastic small round-cell tumor in a young man. Computed tomography showed an extensive peritoneal and mesenteric disease with gross bulky masses, direct liver invasion, and lymph node involvement. This entity should be considered in the differential...
journal_title：European radiology
pub_type： 杂志文章
doi：10.1007/s003300051011
更新日期：2000-01-01 00:00:00
