Abstract:
:The aim of this study was to evaluate the efficiency of the fetal iliac wing angle measurements in the detection of trisomy 21 during the second trimester and the impact of the fetal position on this measurement. During a 43-month period, the iliac wing angle was prospectively measured in 695 fetuses at genetic ultrasonography performed before amniocentesis. The iliac wing angle measurements were performed in a true axial section of the fetal pelvis and the relative position of the fetal spine was recorded (decubitus, lateral). Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and likelihood ratio (LR) were computed for multiple cutoff angles. The prevalence of trisomy 21 was 1.4%; 447 fetuses were in lateral position, 240 fetuses were in decubitus position, including, respectively, 2 and 8 fetuses with trisomy 21 (8 fetuses with other chromosomal anomalies were excluded). In euploid fetuses, the mean iliac wing angle was 83.7 degrees in decubitus and 68.7 degrees in lateral position; in fetuses with trisomy 21 the respective mean angles were 104.9 degrees and 102.5 degrees. A receiver operating characteristics (ROC) curve provided an absolute cutoff angle of 90 degrees, predicting trisomy 21 with a sensitivity of 100%, a specificity of 72.4%, an NPV of 100%, a PPV value of 11.1%, and an LR of 3.6. The measurement of iliac wing angles in an axial section of the fetal pelvis is dependent on spine orientation and provides an efficient cutoff angle for the exclusion of trisomy 21 in patients at risk.
journal_name
Eur Radioljournal_title
European radiologyauthors
Massez A,Rypens F,Metens T,Donner C,Avni FEdoi
10.1007/s00330-003-1896-6subject
Has Abstractpub_date
2003-09-01 00:00:00pages
2075-81issue
9eissn
0938-7994issn
1432-1084journal_volume
13pub_type
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journal_title:European radiology
pub_type: 杂志文章
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abstract::This is a report of clinical, CT and MRI findings in a patient with toxic spongiform leucoencephalopathy after heroin ingestion. The disease is observed in drug addicts who inhale pre-heated heroin. The clinical onset, which usually occurs some days or even longer after the last heroin consumption, is characterized by...
journal_title:European radiology
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journal_title:European radiology
pub_type: 杂志文章,随机对照试验
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更新日期:2014-07-01 00:00:00
abstract:OBJECTIVES:To determine the sensitivity and positive predictive value (PPV) of gadobenate-enhanced MR imaging for the detection of liver metastases. METHODS:This systematic review and meta-analysis was conducted according to PRISMA guidelines. A comprehensive search (EMBASE, PubMed) was performed to identify relevant ...
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pub_type: 杂志文章,meta分析
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更新日期:2006-12-01 00:00:00
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更新日期:2002-11-01 00:00:00
abstract::Sclerosing stromal tumor is a rare ovarian neoplasm. We describe the radiologic findings of sclerosing stromal tumor in two patients. In both patients, MR and CT images showed a large mass in the left adnexal region. On dynamic contrast-enhanced images, the tumors showed early peripheral enhancement with centripetal p...
journal_title:European radiology
pub_type: 杂志文章
doi:10.1007/s003300050844
更新日期:1999-01-01 00:00:00
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更新日期:1999-01-01 00:00:00
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