LuxO controls luxR expression in Vibrio harveyi: evidence for a common regulatory mechanism in Vibrio.

abstract：:The process of septation requires precise temporal and spatial organization of penicillin binding proteins (PBPs) and associated proteins for the deposition of new cell wall material. In most bacteria, the filamentous protein FtsZ organises PBPs into assemblies at the midcell which then constrict inwards as peptidogly...

journal_title：Molecular microbiology

authors： Cadby IT,Lovering AL

更新日期：2014-10-01 00:00:00

abstract：:The mechanistic details of the pathogenesis of Chlamydia, an obligate intracellular pathogen of global importance, have eluded scientists due to the scarcity of traditional molecular genetic tools to investigate this organism. Here we report a chemical biology strategy that has uncovered the first essential protease f...

journal_title：Molecular microbiology

authors： Gloeckl S,Ong VA,Patel P,Tyndall JD,Timms P,Beagley KW,Allan JA,Armitage CW,Turnbull L,Whitchurch CB,Merdanovic M,Ehrmann M,Powers JC,Oleksyszyn J,Verdoes M,Bogyo M,Huston WM

更新日期：2013-08-01 00:00:00

abstract：:DNA double-strand break repair can be accomplished by homologous recombination when a sister chromatid or a homologous chromosome is available. However, the study of sister chromatid double-strand break repair in prokaryotes is complicated by the difficulty in targeting a break to only one copy of two essentially iden...

journal_title：Molecular microbiology

authors： Cromie GA,Leach DR

更新日期：2001-08-01 00:00:00

abstract：:A novel growth phase-associated two-component-type regulator, Fas (fibronectin/fibrinogen binding/haemolytic activity/streptokinase regulator), of Streptococcus pyogenes was identified in the M1 genome sequence, based on homologies to the histidine protein kinase (HPK) and response regulator (RR) part of the Staphyloc...

journal_title：Molecular microbiology

authors： Kreikemeyer B,Boyle MD,Buttaro BA,Heinemann M,Podbielski A

更新日期：2001-01-01 00:00:00

abstract：:Agrobacterium tumefaciens is a plant pathogen that persists as surface-associated populations on plants or soil particles. A genetic screen for A. tumefaciens mutants deficient for surface interactions identified a mutant that forms thin, sparsely populated biofilms, but is proficient for initial attachment. The mutan...

journal_title：Molecular microbiology

authors： Ramey BE,Matthysse AG,Fuqua C

更新日期：2004-06-01 00:00:00

abstract：:Helicobacter pylori colonizes the human stomach and is a potential cause of peptic ulceration or gastric adenocarcinoma. H. pylori secretes a pore-forming toxin known as vacuolating cytotoxin A (VacA). The 88 kDa secreted VacA protein, composed of an N-terminal p33 domain and a C-terminal p55 domain, assembles into wa...

journal_title：Molecular microbiology

authors： Pyburn TM,Foegeding NJ,González-Rivera C,McDonald NA,Gould KL,Cover TL,Ohi MD

更新日期：2016-10-01 00:00:00

abstract：:Candida albicans is the single, most frequently isolated human fungal pathogen. As with most fungal pathogens, the factors which contribute to pathogenesis in C. albicans are not known, despite more than a decade of molecular genetic analysis. Candida albicans was thought to be asexual until the discovery of the MTL l...

journal_title：Molecular microbiology

authors： Magee BB,Legrand M,Alarco AM,Raymond M,Magee PT

更新日期：2002-12-01 00:00:00

abstract：:Stable RNA maturation is a key process in the generation of functional RNAs, and failure to correctly process these RNAs can lead to their elimination through quality control mechanisms. Studies of the maturation pathways of ribosomal RNA and transfer RNA in Bacillus subtilis showed they were radically different from ...

journal_title：Molecular microbiology

authors： Gilet L,DiChiara JM,Figaro S,Bechhofer DH,Condon C

更新日期：2015-01-01 00:00:00

abstract：:Pseudomonas aeruginosa can express two distinct forms of lipopolysaccharide (LPS), called A-band and B-band. As an attempt to understand the molecular biology of the synthesis and regulation of these LPS antigens, a recombinant plasmid, pFV3, containing genes for A-band expression was isolated previously. In the prese...

journal_title：Molecular microbiology

authors： Lightfoot J,Lam JS

更新日期：1993-05-01 00:00:00

abstract：:Proteus mirabilis is a common cause of urinary tract infection (UTI) in individuals with structural abnormalities or long-term catheterization. The expression of mannose-resistant/Proteus-like (MR/P) fimbria is phase variable because of the inversion of a 251 bp DNA fragment that carries the promoter for the mrp opero...

journal_title：Molecular microbiology

authors： Li X,Lockatell CV,Johnson DE,Mobley HL

更新日期：2002-08-01 00:00:00

abstract：:The de novo purine biosynthetic enzymes 5-amino-4-imidazolecarboxamide-ribonucleotide (AICAR) transformylase (EC 2.1.2.3), IMP cyclohydrolase (EC 3.5.4.10) and glycineamide-ribonucleotide (GAR) synthetase (EC 2.1.2.2) are encoded by the purHD locus of Escherichia coli. The DNA sequence of this locus revealed two open ...

journal_title：Molecular microbiology

authors： Flannigan KA,Hennigan SH,Vogelbacker HH,Gots JS,Smith JM

更新日期：1990-03-01 00:00:00

abstract：:We have followed the time-dependent transfection of Paramecium cells with a vector containing the gene of green fluorescent protein (GFP) attached to the C-terminus of the PtSERCA1 gene. The outlines of alveolar sacs (ASs) are labelled, as is the endoplasmic reticulum (ER) throughout the cell. When GFP fluorescence is...

journal_title：Molecular microbiology

authors： Hauser K,Pavlovic N,Klauke N,Geissinger D,Plattner H

更新日期：2000-08-01 00:00:00

abstract：:Cytochrome b558 in the cytoplasmic membrane of Bacillus subtilis constitutes the anchor and electron acceptor to the flavoprotein (Fp) and iron-sulphur protein (Ip) in succinate:quinone oxidoreductase, and seemingly contains two haem groups. EPR and MCD spectroscopic data indicate bis-imidazole ligation of the haem. A...

journal_title：Molecular microbiology

authors： Fridén H,Hederstedt L

更新日期：1990-06-01 00:00:00

abstract：:When they infect Escherichia coli cells, the filamentous phages IF1 and fd first interact with a pilus and then target TolA as their common receptor. They use the domains N2 and N1 of their gene-3-proteins (G3P) for these interactions but differ in the mechanism of infection. In G3P of phage IF1, N1 and N2 are indepen...

journal_title：Molecular microbiology

authors： Lorenz SH,Schmid FX

更新日期：2011-05-01 00:00:00

abstract：:A detailed transcriptional analysis of the conjugative transposon Tn916 was carried out, which revealed that transcription of the transfer functions requires excision of the element and dramatically increases in the presence of tetracycline. The key components of this regulatory system are two contiguous transposon-bo...

journal_title：Molecular microbiology

authors： Celli J,Trieu-Cuot P

更新日期：1998-04-01 00:00:00

abstract：:Candida albicans hypha formation which has been stimulated via the Ras1-cAMP-Efg1 signalling cascade is inhibited by farnesol, a C. albicans autoregulatory factor, and small molecules such as dodecanol. In cultures containing farnesol or dodecanol, hypha formation was restored upon addition of dibutyryl-cAMP. The CAI4...

journal_title：Molecular microbiology

authors： Davis-Hanna A,Piispanen AE,Stateva LI,Hogan DA

更新日期：2008-01-01 00:00:00

abstract：:The flagellar genes of Caulobacter crescentus are expressed under cell-cycle control. Expression is regulated by both flagellar assembly cues and cell-cycle events. In this paper we define the sequences required for the expression of the flgF operon, a new class of sigma 54 flagellar promoter. This promoter type is ex...

journal_title：Molecular microbiology

authors： Marques MV,Gober JW

更新日期：1995-04-01 00:00:00

abstract：:Regulation of DNA replication in Bacillus subtilis involves a post-initiation mechanism which is subject to control by the Stringent System, an essential regulatory network, mediated by the alarmone, ppGpp. In detailed studies using DNA-DNA hybridization procedures, we have now shown that, following the induction of t...

journal_title：Molecular microbiology

authors： Levine A,Autret S,Séror SJ

更新日期：1995-01-01 00:00:00

abstract：:Acetyl-coenzyme A synthetase (Acs) activates acetate into acetyl-coenzyme A (Ac-CoA) in most cells. In Salmonella enterica, acs expression and Acs activity are controlled. It is unclear why the sirtuin-dependent protein acylation/deacylation system (SDPADS) controls the activity of Acs. Here we show that, during growt...

journal_title：Molecular microbiology

authors： Chan CH,Garrity J,Crosby HA,Escalante-Semerena JC

更新日期：2011-04-01 00:00:00

abstract：:Genes acrAB encode a multidrug efflux pump in Escherichia coli. We have previously reported that transcription of acrAB is increased under general stress conditions (i.e. 4% ethanol, 0.5 M NaCl, and the stationary phase in Luria-Bertani medium). In this study, lacZ transcriptional fusions and an in vitro gel mobility ...

journal_title：Molecular microbiology

authors： Ma D,Alberti M,Lynch C,Nikaido H,Hearst JE

更新日期：1996-01-01 00:00:00

abstract：:The two-component regulatory system PhoPQ has been shown to regulate the expression of virulence factors in a number of bacterial species. For one such virulence factor, lipopolysaccharide (LPS), the PhoPQ system has been shown to regulate structural modifications in Salmonella enterica var Typhimurium. In Yersinia pe...

journal_title：Molecular microbiology

authors： Hitchen PG,Prior JL,Oyston PC,Panico M,Wren BW,Titball RW,Morris HR,Dell A

更新日期：2002-06-01 00:00:00

abstract：:Small GTP-binding proteins of the highly conserved Rho family act as molecular switches regulating cell signalling, cytoskeletal organization and vesicle trafficking in eukaryotic cells. Here we show that in the dimorphic plant pathogenic fungus Ustilago maydis deletion of either cdc42 or rac1 results in loss of virul...

journal_title：Molecular microbiology

authors： Mahlert M,Leveleki L,Hlubek A,Sandrock B,Bölker M

更新日期：2006-01-01 00:00:00

abstract：:We have identified and characterized three genes, SUT1, SUT2 and SUT3, that encode glucose transporters of the yeast Pichia stipitis. When expressed in a Saccharomyces cerevisiae hxt null mutant strain that is unable to take up monosaccharides, all three proteins restored growth on glucose. Sequencing of the genes rev...

journal_title：Molecular microbiology

authors： Weierstall T,Hollenberg CP,Boles E

更新日期：1999-02-01 00:00:00

abstract：:Streptococcus mutans, a commensal of the human oral cavity, can survive in the bloodstream and cause infective endocarditis (IE). However, the virulence factors associated with this manifestation of disease are not known. Here, we demonstrate that AtlA, an autolysin of S. mutans is a newly identified fibronectin (Fn) ...

journal_title：Molecular microbiology

authors： Jung CJ,Zheng QH,Shieh YH,Lin CS,Chia JS

更新日期：2009-11-01 00:00:00

abstract：:SigD and SigE (Salmonella invasion gene) are proteins needed for optimal invasion of Salmonella typhimurium into eukaryotic cells in vitro. SigD is a secreted protein and SigE is a putative chaperone required for SigD stability and/or secretion. SigD is secreted by a type III secretion apparatus encoded within a patho...

journal_title：Molecular microbiology

authors： Darwin KH,Miller VL

更新日期：2000-02-01 00:00:00

abstract：:Several bacterial genera express proteins that contain collagen-like regions, which are associated with variable (V) non-collagenous regions. The streptococcal collagen-like proteins, Scl1 and Scl2, of group A Streptococcus (GAS) are members of this 'prokaryotic collagen' family, and they too contain an amino-terminal...

journal_title：Molecular microbiology

authors： Han R,Caswell CC,Lukomska E,Keene DR,Pawlowski M,Bujnicki JM,Kim JK,Lukomski S

更新日期：2006-07-01 00:00:00

abstract：:We report the construction and the expression in Escherichia coli of three different fusion genes encoding the extended human IgG3 hinge region (Hi) fused in-phase to the C-terminal end of bacterial TEM1 beta-lactamase (Bla). In the first fusion gene blahi, TEM1 beta-lactamase (Bla). In the first fusion gene blahi, th...

journal_title：Molecular microbiology

authors： De Sutter K,Remaut E,Fiers W

更新日期：1992-08-01 00:00:00

abstract：:Candida albicans is an opportunistic fungal pathogen. In immunocompromised individuals, it can cause bloodstream infections with high mortality rates. The ability to switch between yeast and hyphal morphologies is a critical virulence factor of C. albicans. In response to diverse environmental cues, several signaling ...

journal_title：Molecular microbiology

authors： Chen C,Zeng G,Wang Y

更新日期：2018-10-01 00:00:00

abstract：:GS-1 (ncu04189) is a protein required for the synthesis of beta-1,3-glucan in Neurospora crassa. As chitin, beta-1,3-glucan is a morphogenetically relevant component of the fungal cell wall. Previously, we showed that chitin synthases are delivered to the growing hyphal tip of N. crassa by secretory microvesicles that...

journal_title：Molecular microbiology

authors： Verdín J,Bartnicki-Garcia S,Riquelme M

更新日期：2009-12-01 00:00:00

abstract：:Mycobacterium tuberculosis infects one-third of the world's population and causes two million deaths annually. The unusually low permeability of its cell wall contributes to the ability of M. tuberculosis to grow within host macrophages, a property required for pathogenesis of infection. Mycobacterium marinum is an es...

journal_title：Molecular microbiology

authors： Gao LY,Laval F,Lawson EH,Groger RK,Woodruff A,Morisaki JH,Cox JS,Daffe M,Brown EJ

更新日期：2003-09-01 00:00:00