Abstract:
:The purpose of the study is to observe the relation between anthropometric measurements, focusing on sagittal abdominal diameter (SAD), and insulin sensitivity indices in Chinese hypertensive patients and their siblings. In total, 907 participants, 537 hypertensive and 370 nonhypertensive, from 311 Taiwanese families were drawn from the Stanford Asia and Pacific Program for Hypertension and Insulin Resistance for the study. The participants received anthropometric measurements and 75-g oral glucose tolerance tests after an overnight fast. Fasting insulin, homeostasis model assessment for insulin resistance (HOMA-IR), and the insulin sensitivity index ISI(0,120) were chosen as surrogate measures of insulin sensitivity. In addition to Pearson and partial correlations, we used generalized estimating equations (GEEs) to examine the association between anthropometric measurements and insulin sensitivity indices. A small deviance in the GEEs indicates the goodness of model fit, irrespective of the independence among variables. The hypertensive patients were older in age, wider in waist circumference (WC), larger in body mass index (BMI) and SAD, and more insulin resistant than the nonhypertensive counterparts. The logarithmic transformation of fasting insulin, HOMA-IR, and ISI(0,120) significantly correlated with SAD, WC, and BMI before and after adjustments for age and sex. The deviances of SAD in the GEEs were similar to those of WC in all subjects, while BMI had smaller deviances than SAD and WC in the hypertensive patients. Our results suggest that the performance of SAD in predicting insulin sensitivity is comparable with WC in Chinese hypertensive patients and their siblings. BMI, however, seems to have better association with insulin sensitivity than SAD and WC in the patients with hypertension.
journal_name
J Hum Hypertensjournal_title
Journal of human hypertensionauthors
Hwu CM,Hsiao CF,Sheu WH,Pei D,Tai TY,Quertermous T,Rodriguez B,Pratt R,Chen YD,Ho LTdoi
10.1038/sj.jhh.1001532subject
Has Abstractpub_date
2003-03-01 00:00:00pages
193-8issue
3eissn
0950-9240issn
1476-5527pii
1001532journal_volume
17pub_type
杂志文章,多中心研究abstract::The 2017 American Academy of Pediatrics (AAP) guideline for assessing "elevated blood pressure (BP) (90th BP percentile)" and "high BP (95th BP percentile)" includes a large number of BP cut-offs based on sex, age and height, which makes it cumbersome to use in clinical practice. We developed and evaluated the perform...
journal_title:Journal of human hypertension
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abstract::Coronary heart disease (CHD) is still relatively uncommon in the black population of South Africa. We embarked on a study to determine the prevalence of risk factors leading to CHD in the black population of Durban. The study sample was selected from patients attending a dental clinic at a hospital. A total of 458 Zul...
journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
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journal_title:Journal of human hypertension
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journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,随机对照试验
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abstract::There are complications in diagnosing hypertension in children and adolescents due to variation of blood pressure (BP) values to age, gender and height. This study was aimed at assessing whether the performance of BP-to-height ratio (BPHR) can be an effective tool for screening prehypertension and hypertension in Elli...
journal_title:Journal of human hypertension
pub_type: 杂志文章
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journal_title:Journal of human hypertension
pub_type: 杂志文章,随机对照试验
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journal_title:Journal of human hypertension
pub_type: 杂志文章
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journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2015.27
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journal_title:Journal of human hypertension
pub_type: 杂志文章
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journal_title:Journal of human hypertension
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journal_title:Journal of human hypertension
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Journal of human hypertension
pub_type: 杂志文章,meta分析
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journal_title:Journal of human hypertension
pub_type: 杂志文章,meta分析,多中心研究
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更新日期:2016-12-01 00:00:00
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journal_title:Journal of human hypertension
pub_type: 杂志文章
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journal_title:Journal of human hypertension
pub_type: 杂志文章,多中心研究,随机对照试验
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pub_type: 杂志文章
doi:10.1038/s41371-020-0320-x
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journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:10.1038/jhh.2013.102
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journal_title:Journal of human hypertension
pub_type: 杂志文章
doi:
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journal_title:Journal of human hypertension
pub_type: 杂志文章,随机对照试验
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journal_title:Journal of human hypertension
pub_type: 杂志文章
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journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章,随机对照试验
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pub_type: 杂志文章,评审
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journal_title:Journal of human hypertension
pub_type: 杂志文章
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journal_title:Journal of human hypertension
pub_type: 临床试验,杂志文章
doi:
更新日期:1995-04-01 00:00:00
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journal_title:Journal of human hypertension
pub_type: 杂志文章
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journal_title:Journal of human hypertension
pub_type: 杂志文章,随机对照试验
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更新日期:2011-04-01 00:00:00
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journal_title:Journal of human hypertension
pub_type: 杂志文章
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journal_title:Journal of human hypertension
pub_type: 杂志文章
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journal_title:Journal of human hypertension
pub_type: 杂志文章
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journal_title:Journal of human hypertension
pub_type: 杂志文章,多中心研究
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