Recording of ENGs from the nerves innervating the pancreas of a dog during the intravenous glucose tolerance test.


:Electroneurograms (ENGs) from the vagus nerve (VN), the splanchnic nerve (SN) and the pancreatic nerve (PN) innervating the pancreas of a dog, were recorded with chronically implanted 33-electrode spiral cuffs (cuff) before and after the pancreas were stimulated with intravenously (i.v.) administered glucose. In the cuffs platinum electrodes were arranged in three parallel spiral groups containing 11 electrodes on the inner surface. The cuffs had an inner diameter of 2 mm and a length of 18 mm. In a two-year study, the cuffs were implanted into two Beagle dogs and were also used for pancreatic stimulation, although this is not described in this paper. In the VN, the cuff was installed on the nerve at the neck, whilst in the SN, the cuff was installed on the nerve before the celiac ganglion, and in the PN, the cuff was installed on the nerve just before it enters the pancreas. Six months after implantation, when the model of interpretation of the results was developed, three recordings of ENG in each animal were conducted. The first one was conducted in the unstimulated pancreas while the second and the third were conducted 1 and 8 min after a known amount of glucose was i.v. administered. Since the results obtained in both animals were actually quite similar, we present the results obtained in one animal. To evaluate the changes in superficial activity of the nerves, elicited by the administration of glucose, the power spectra corresponding to ENGs, recorded from the nerves before and after the administration of glucose, were integrated within the band of frequencies ranging from 1 to 5 kHz. Accordingly, the magnitude of the integrated power spectrum (MIPS), corresponding to the ENG recorded from the SN before administration of glucose, was 2.863 au. One minute after glucose was administered the value fell to 2.795 au while 8 min after the administration the value returned to 2.8 au. The MIPS corresponding to the ENG recorded from the PN before the administration of glucose was 3.236 au. One minute after the administration the value fell to 2.901 au while 8 min after the administration the value rose to 3.009 au. The MIPS, corresponding to the ENG recorded from the VN before the administration of glucose, was 3.656 au. One minute after the administration the value fell to 3.565 au. Eight minutes after the administration the value rose to 3.689 au. The results show that 1 min after glucose was administered superficial activity in all three nerves was reduced while 8 min after administration the activity in the nerves returned to the same level of activity before the glucose was administered. This information could be effectively used in a further study of pancreatic innervation and its function. Moreover, the results suggest that cuffs could also be useful in recording the ENGs from other nerves of the autonomic nervous system that innervate various glands and internal organs.


Physiol Meas


Rozman J,Zorko B,Bunc M,Mikac U,Tegou E




Has Abstract


2002-11-01 00:00:00












  • Correlation between maximal radial muscle displacement and stiffness in gastrocnemius muscle.

    abstract:OBJECTIVE:Tensiomyography (TMG) and myotonometry (MMT) are two novel technologies that measure neuromuscular properties. These two devices measure the stiffness of the soft tissue as well as other variables. The aim of this study is to analyze if there is any correlation between maximal radial displacement (Dm) and Sti...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Labata-Lezaun N,López-de-Celis C,Llurda-Almuzara L,González-Rueda V,Cadellans-Arróniz A,Pérez-Bellmunt A

    更新日期:2020-12-31 00:00:00

  • Feasibility of long-term cerebral and peripheral regional tissue oxygen saturation measurements.

    abstract::The aim of this study was to analyse the feasibility of long-term measurements of cerebral (crSO2) and peripheral (prSO2) regional tissue oxygen saturation on the first day of life by determining the amount of artefacts and their influence on rSO2. Near infrared spectroscopy (NIRS) measurements were performed fronto-p...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Schmitz J,Pichler G,Schwaberger B,Urlesberger B,Baik N,Binder C

    更新日期:2014-07-01 00:00:00

  • Dynamic time warping and machine learning for signal quality assessment of pulsatile signals.

    abstract::In this work, we describe a beat-by-beat method for assessing the clinical utility of pulsatile waveforms, primarily recorded from cardiovascular blood volume or pressure changes, concentrating on the photoplethysmogram (PPG). Physiological blood flow is nonstationary, with pulses changing in height, width and morphol...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Li Q,Clifford GD

    更新日期:2012-09-01 00:00:00

  • Microfluidics for flow cytometric analysis of cells and particles.

    abstract::This review describes recent developments in microfabricated flow cytometers and related microfluidic devices that can detect, analyze, and sort cells or particles. The high-speed analytical capabilities of flow cytometry depend on the cooperative use of microfluidics, optics and electronics. Along with the improvemen...

    journal_title:Physiological measurement

    pub_type: 杂志文章,评审


    authors: Huh D,Gu W,Kamotani Y,Grotberg JB,Takayama S

    更新日期:2005-06-01 00:00:00

  • Electrical impedance myography at frequencies up to 2 MHz.

    abstract::Extension of the frequency range of electrical impedance myography (EIM) to 2 MHz discloses a major rise in the reactance of muscle above 3-500 kHz, together with a slow decrease in the resistance consonant with the Kramers-Kronig relations. This 'upturn' phenomenon is found when the distant current electrode configur...

    journal_title:Physiological measurement

    pub_type: 临床试验,杂志文章


    authors: Shiffman CA,Kashuri H,Aaron R

    更新日期:2008-06-01 00:00:00

  • Is dynamic cerebral autoregulation measurement using transcranial Doppler ultrasound reproducible in the presence of high concentration oxygen and carbon dioxide?

    abstract::Reliability of cerebral blood flow velocity (CBFV) and dynamic cerebral autoregulation estimates (expressed as autoregulation index: ARI) using spontaneous fluctuations in blood pressure (BP) has been demonstrated. However, reliability during co-administration of O2 and CO2 is unknown. Bilateral CBFV (using transcrani...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Minhas JS,Syed NF,Haunton VJ,Panerai RB,Robinson TG,Mistri AK

    更新日期:2016-05-01 00:00:00

  • Gastric activity studies using a magnetic tracer.

    abstract::A magnetic pulse generator has been set up in order to study gastric activity. Two coils 1.05 m in diameter, arranged in a Helmholtz configuration, were used. The system generated magnetic field pulses higher than 15 mT, of duration 17.3+/-1.2 ms. Measurements were performed in 11 male volunteers, with average age 29....

    journal_title:Physiological measurement

    pub_type: 临床试验,杂志文章


    authors: Cordova-Fraga T,Bernal-Alvarado JJ,Gutierrez-Juarez G,Sosa M,Vargas-Luna M

    更新日期:2004-10-01 00:00:00

  • Measuring gait with an accelerometer-based wearable: influence of device location, testing protocol and age.

    abstract::Wearables such as accelerometers are emerging as powerful tools for quantifying gait in various environments. Flexibility in wearable location may improve ease of use and data acquisition during instrumented testing. However, change of location may impact algorithm functionality when evaluating associated gait charact...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Del Din S,Hickey A,Hurwitz N,Mathers JC,Rochester L,Godfrey A

    更新日期:2016-10-01 00:00:00

  • Generalizability of extracellular-to-intracellular fluid ratio using bio-impedance spectroscopy.

    abstract::Generalizability theory was used to investigate the score consistency of observed extracellular fluid/intracellular fluid (ECF/ICF) ratio measurements for both the global and leg-segmental bio-impedance spectroscopy methods. The test instrument used was a Xitron Hydra ECF/ICF Bio-Impedance Analyzer System, model 4200 ...

    journal_title:Physiological measurement

    pub_type: 杂志文章,随机对照试验


    authors: Turner AA,Lozano-Nieto A,Bouffard M

    更新日期:2006-04-01 00:00:00

  • Validation of a finite-element solution for electrical impedance tomography in an anisotropic medium.

    abstract::Electrical impedance tomography is an imaging method, with which volumetric images of conductivity are produced by injecting electrical current and measuring boundary voltages. It has the potential to become a portable non-invasive medical imaging technique. Until now, implementations have neglected anisotropy even th...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Abascal JF,Arridge SR,Lionheart WR,Bayford RH,Holder DS

    更新日期:2007-07-01 00:00:00

  • Effect of organic and inorganic nitrates on cerebrovascular pulsatile power transmission in patients with heart failure and preserved ejection fraction.

    abstract:OBJECTIVE:Increased penetration of pulsatile power to the brain has been implicated in the pathogenesis of age-related cognitive dysfunction and dementia, a common comorbidity in patients with heart failure and preserved ejection fraction (HFpEF). However, there is a lack of knowledge on the effects of organic and inor...

    journal_title:Physiological measurement

    pub_type: 杂志文章,随机对照试验


    authors: Londono-Hoyos F,Zamani P,Beraun M,Vasim I,Segers P,Chirinos JA

    更新日期:2018-04-20 00:00:00

  • Assessment of hepatic fatty infiltration using dual-energy computed tomography: a phantom study.

    abstract::The purpose of this study was to examine the performance of dual-energy computed tomography (DECT) for the quantification of liver fat content (LFC). We prepared two phantoms: homogenized mixtures of porcine liver and fat and homogeneous mixtures of liver- and fat-equivalent solutions. Tubes containing mixtures with k...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Li JH,Tsai CY,Huang HM

    更新日期:2014-04-01 00:00:00

  • Measurement of pupil reactivity using fast pupillometry.

    abstract::Analysis of human eye pupil reactivity is a very valuable diagnostic method used mainly for evaluation of the condition of the autonomic nervous system and the visual system. The paper presents an experimental pupillometer built in the Institute of Physics of the Wroclaw University of Technology. The apparatus makes i...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Hachol A,Szczepanowska-Nowak W,Kasprzak H,Zawojska I,Dudzinski A,Kinasz R,Wygledowska-Promienska D

    更新日期:2007-01-01 00:00:00

  • PET(CO2) measurement and feature extraction of capnogram signals for extubation outcomes from mechanical ventilation.

    abstract::Capnography is a continuous and noninvasive method for carbon dioxide (CO2) measurement, and it has become the standard of care for basic respiratory monitoring for intubated patients in the intensive care unit. In addition, it has been used to adjust ventilatory parameters during mechanical ventilation (MV). However,...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Rasera CC,Gewehr PM,Domingues AM

    更新日期:2015-02-01 00:00:00

  • Time variation of ammonia, acetone, isoprene and ethanol in breath: a quantitative SIFT-MS study over 30 days.

    abstract::A study of the concentrations of the common breath metabolites ammonia, acetone, isoprene, ethanol and acetaldehyde in the breath of five subjects over a period of 30 days has been carried out. Breath samples were taken and analysed in the early morning on arrival at the laboratory. The real time analyses of three con...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Diskin AM,Spanel P,Smith D

    更新日期:2003-02-01 00:00:00

  • Cooperative dry-electrode sensors for multi-lead biopotential and bioimpedance monitoring.

    abstract::Cooperative sensors is a novel measurement architecture that allows the acquiring of biopotential signals on patients in a comfortable and easy-to-integrate manner. The novel sensors are defined as cooperative in the sense that at least two of them work in concert to measure a target physiological signal, such as a mu...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Rapin M,Proença M,Braun F,Meier C,Solà J,Ferrario D,Grossenbacher O,Porchet JA,Chételat O

    更新日期:2015-04-01 00:00:00

  • An electrical impedance tomography system for gynecological application GIT with a tiny electrode array.

    abstract::The paper describes the development of an electrical impedance tomography (EIT) system for gynecologic research. The GIT (gynecological impedance tomography) system has 48 electrodes and is embedded on a small space (30 mm diameter and 20 mm height) inside of the vaginal probe. The system provides real-time (one shot ...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: V A C,Y V G,A V K,S A S,T S T

    更新日期:2012-05-01 00:00:00

  • Are ejection fractions from gated SPECT perfusion studies clinically useful? A comparison with radionuclide ventriculography.

    abstract::Gated SPECT (GSPECT) was evaluated for the measurement of left ventricular ejection fraction (LVEF) by comparing with equilibrium gated radionuclide ventriculography (RNVG). A total of 99 subjects underwent GSPECT and RNVG imaging. All studies were acquired in list mode with GSPECT studies processed to give 16- and 8-...

    journal_title:Physiological measurement

    pub_type: 临床试验,杂志文章


    authors: Wright GA,McDade M,Keeble W,Martin W,Hutton I

    更新日期:2001-05-01 00:00:00

  • Differences in the microcirculatory effects of local skin surface contact pressure stimulation between acupoints and nonacupoints: possible relevance to acupressure.

    abstract::In the present study, laser Doppler measurement was used to quantitatively investigate the microcirculatory effects of contact pressure stimulation (PS) underneath the Hoku acupoint and its nearby nonacupoint, to improve the understanding of the mechanisms underlying acupressure therapy. A control group (no PS applied...

    journal_title:Physiological measurement

    pub_type: 临床试验,杂志文章


    authors: Hsiu H,Hsu WC,Chen BH,Hsu CL

    更新日期:2010-06-01 00:00:00

  • The effect of ambient air temperature on whole-body bioelectrical impedance.

    abstract::It has previously been shown that extreme changes in ambient air temperature can affect whole-body bioelectrical impedance. The purpose of this study was to determine if more moderate changes in ambient air temperature, such as those experienced in most laboratory settings, would also affect bioelectric impedance anal...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Buono MJ,Burke S,Endemann S,Graham H,Gressard C,Griswold L,Michalewicz B

    更新日期:2004-02-01 00:00:00

  • Energy scavenging sources for biomedical sensors.

    abstract::Energy scavenging has increasingly become an interesting option for powering electronic devices because of the almost infinite lifetime and the non-dependence on fuels for energy generation. Moreover, the rise of wireless technologies promises new applications in medical monitoring systems, but these still face limita...

    journal_title:Physiological measurement

    pub_type: 杂志文章,评审


    authors: Romero E,Warrington RO,Neuman MR

    更新日期:2009-09-01 00:00:00

  • Choice of reconstructed tissue properties affects interpretation of lung EIT images.

    abstract::Electrical impedance tomography (EIT) estimates an image of change in electrical properties within a body from stimulations and measurements at surface electrodes. There is significant interest in EIT as a tool to monitor and guide ventilation therapy in mechanically ventilated patients. In lung EIT, the EIT inverse p...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Grychtol B,Adler A

    更新日期:2014-06-01 00:00:00

  • Neural network analysis of oxygenation signals in infants during sleep.

    abstract::The use of artificial neural networks (ANNs) to interpret sleep monitoring signals is described. Recordings from ten infants with apparent life threatening episodes were assigned into training feedforward R-PROP networks. In order to separate good signal from artefact, 60 second time frames of SaO2 and TcPO2 signals w...

    journal_title:Physiological measurement

    pub_type: 临床试验,杂志文章


    authors: Taktak AF,Simpson S,Patel S,Meyer G

    更新日期:2000-08-01 00:00:00

  • Improved ultrasound transducer positioning by fetal heart location estimation during Doppler based heart rate measurements.

    abstract:OBJECTIVE:Doppler ultrasound (US) is the most commonly applied method to measure the fetal heart rate (fHR). When the fetal heart is not properly located within the ultrasonic beam, fHR measurements often fail. As a consequence, clinical staff need to reposition the US transducer on the maternal abdomen, which can be a...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Hamelmann P,Vullings R,Schmitt L,Kolen AF,Mischi M,van Laar JOEH,Bergmans JWM

    更新日期:2017-09-21 00:00:00

  • A comparison of methods for measurement of spatial resolution in two-dimensional circular EIT images.

    abstract::The literature concerning measurement of spatial resolution in electrical impedance tomography (EIT) is vague. Different groups often use their own method or a modified version of a better known method, thus hindering a generalized resolution measurement which could be useful for gauging the performance of one system ...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Wheeler JL,Wang W,Tang M

    更新日期:2002-02-01 00:00:00

  • Arterial blood pressure measurement and pulse wave analysis--their role in enhancing cardiovascular assessment.

    abstract::The most common method of clinical measurement of arterial blood pressure is by means of the cuff sphygmomanometer. This instrument has provided fundamental quantitative information on arterial pressure in individual subjects and in populations and facilitated estimation of cardiovascular risk related to levels of blo...

    journal_title:Physiological measurement

    pub_type: 历史文章,杂志文章,评审


    authors: Avolio AP,Butlin M,Walsh A

    更新日期:2010-01-01 00:00:00

  • Effects of CO2 on dynamic cerebral autoregulation measurement.

    abstract::Arterial pCO2 is known to influence cerebral autoregulation but its effect on the dynamic relationship between mean arterial blood pressure (ABP) and mean cerebral blood flow velocity (CBFV), obtained from spontaneous fluctuations in ABP, has not been established. In 16 normal subjects, ABP was measured non-invasively...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Panerai RB,Deverson ST,Mahony P,Hayes P,Evans DH

    更新日期:1999-08-01 00:00:00

  • Potential neuroprotective effects of acupuncture stimulation on diabetes mellitus in a global ischemic rat model.

    abstract::Acupuncture (ACU) is known to be effective in ischemia treatment, and glutamate (GLU) excitotoxicity is an important factor in neuronal cell death. We observed the effect of ACU on cerebral blood flow (%CBF) and DeltaGLU (the changes in GLU release) in the ischemic stroke rat model of diabetic mellitus (DM). A global ...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Choi S,Lee GJ,Chae SJ,Kang SW,Yin CS,Lee SH,Choi SK,Park HK

    更新日期:2010-05-01 00:00:00

  • Ballistocardiography and seismocardiography detection of hemodynamic changes during simulated obstructive apnea.

    abstract:OBJECTIVE:To investigate if modern seismocardiography (SCG) and ballistocardiography (BCG) are useful in the detection of hemodynamic changes occurring during simulated obstructive apneic events. METHODS:Forty-seven healthy volunteers performed a voluntary maximum Mueller maneuver (MM) for 10 s, and SCG and BCG signal...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Morra S,Hossein A,Gorlier D,Rabineau J,Chaumont M,Migeotte PF,Van De Borne P

    更新日期:2020-07-09 00:00:00

  • Modelling the cerebral haemodynamic response in the physiological range of PaCO2.

    abstract:OBJECTIVE:Arterial CO2 (PaCO2) has a strong effect on cerebral blood flow (CBF), but its influence on CBF regulatory mechanisms and circulatory systemic variables has not been fully described over the entire physiological range of PaCO2. APPROACH:CBF velocity (CBFV, transcranial Doppler), blood pressure (BP, Finometer...

    journal_title:Physiological measurement

    pub_type: 杂志文章


    authors: Minhas JS,Panerai RB,Robinson TG

    更新日期:2018-06-19 00:00:00