Successful single donor islet allotransplantation in the streptozotocin diabetes rat model.

abstract：:Neural progenitor cells (NPCs) overexpressing fibroblast growth factor 2 (FGF-2) have the distinct tendency to associate with the vasculature and establish multiple proliferative clusters in the perivascular environment after transplantation into the cerebral cortex. Strikingly, the vascular clusters of progenitor cel...

journal_title：Cell transplantation

authors： Tsupykov O,Kanemitsu M,Smozhanik E,Skibo G,Dayer AG,Kiss JZ

更新日期：2016-01-01 00:00:00

abstract：:Regenerative medicine aims to repair and regenerate damaged cells, tissues, and organs in order to restore function. Regeneration can be obtained either by cell replacement or by stimulating the body's own repair mechanisms. Importantly, a favorable environment is required before any regenerative signal can stimulate ...

journal_title：Cell transplantation

authors： Silini AR,Magatti M,Cargnoni A,Parolini O

更新日期：2017-04-13 00:00:00

abstract：:We previously demonstrated that mesenchymal cells from human amniotic membrane (hAMTCs) inhibit the generation and maturation of monocyte-derived dendritic cells (DCs) in vitro. Considering the crucial role of DCs in the immune response and that epithelial cells of the human amniotic membrane (hAECs) share some of the...

journal_title：Cell transplantation

authors： Magatti M,Caruso M,De Munari S,Vertua E,De D,Manuelpillai U,Parolini O

更新日期：2015-01-01 00:00:00

abstract：:Cell therapy has been shown to be a promising alternative therapy for neurorestoration, and more than 30 different types of cells have been shown to possess some capability to restore lost or damaged neurological functions. Chinese physicians have successfully applied cell therapy to many neurological diseases and dam...

journal_title：Cell transplantation

authors： Chinese Branch of International Association of Neurorestoratology (IANR).,Preparatory Committee of Chinese Association of Neurorestoratology.

更新日期：2013-01-01 00:00:00

abstract：:We have recently reported that small-sized bone marrow cells (BMCs) isolated by counterflow centrifugal elutriation and depleted of lineage markers (Fr25lin(-)) have the capacity to differentiate and contribute to regeneration of injured islets. In this study, we assess some of the characteristics of these cells compa...

journal_title：Cell transplantation

authors： Iskovich S,Goldenberg-Cohen N,Sadikov T,Yaniv I,Stein J,Askenasy N

更新日期：2015-01-01 00:00:00

abstract：:Hepatocyte-based biological therapies are increasingly envisioned for temporary support in acute liver failure and provision of specific-liver functions in liver-based metabolic deficiency. One of the hurdles to develop such therapies is severe shortage of human livers for hepatocyte isolation. To address the issue, w...

journal_title：Cell transplantation

authors： Kobayashi N,Tanaka N

更新日期：2002-07-01 00:00:00

abstract：:Parkinson's disease (PD), while primarily associated with degeneration of nigrostriatal dopamine neurons, is now increasingly recognized to have more widespread cell loss and so the most effective cell replacement therapy should target all these neuronal losses. Neural precursor cells might be ideal in this regard as ...

journal_title：Cell transplantation

authors： Jain M,Armstrong RJ,Elneil S,Barker RA

更新日期：2006-01-01 00:00:00

abstract：:Recently, we described a diffusion chamber for a bioartificial endocrine pancreas (Bio-AEP). Pancreatic islet cells in the Bio-AEP device were isolated from the immune system of the host by an artificial barrier, while nutrients, electrolytes, oxygen, and bioactive secretory products were exchanged across this barrier...

journal_title：Cell transplantation

authors： Hirotani S,Eda R,Kawabata T,Fuchinoue S,Teraoka S,Agishi T,Ohgawara H

更新日期：1999-07-01 00:00:00

abstract：:The technologies for adipose tissue harvesting, processing, and transplantation have substantially evolved in the past two decades. Clinically driven advancements have paralleled a significant improvement in the understanding of cellular, molecular, and immunobiological events surrounding cell and tissue transplantati...

journal_title：Cell transplantation

authors： Tremolada C,Palmieri G,Ricordi C

更新日期：2010-01-01 00:00:00

abstract：:Osteoarthritis (OA) is degenerative disease, leading to pain and functional disability. It is reported that polydeoxyribonucleotide (PDRN) is a suitable therapy for OA. However, the therapeutic mechanisms of PDRN in OA are not fully understood. To investigate the effect of PDRN in an in vitro model of OA, interleukin ...

journal_title：Cell transplantation

authors： Baek A,Kim Y,Lee JW,Lee SC,Cho SR

更新日期：2018-11-01 00:00:00

abstract：:Wharton's jelly-derived mesenchymal stromal cells (WJ-MSCs) have distinct immunomodulatory and protective effects against kidney, liver, or heart injury. Limited studies have shown that WJ-MSCs attenuates oxygen-glucose deprivation-mediated inflammation in hippocampal slices. The neuroprotective effect of intracerebra...

journal_title：Cell transplantation

authors： Wu KJ,Yu SJ,Chiang CW,Lee YW,Yen BL,Tseng PC,Hsu CS,Kuo LW,Wang Y

更新日期：2018-11-01 00:00:00

abstract：:Cellular transplantation strategies utilizing intraspinal or intrathecal olfactory ensheathing cells (OECs) have been reported as beneficial for spinal cord injury (SCI). However, there are many disadvantages of these methods, including additional trauma to the spinal cord parenchyma and technical challenges. Therefor...

journal_title：Cell transplantation

authors： Zhang L,Zhuang X,Chen Y,Xia H

更新日期：2019-12-01 00:00:00

abstract：:Prairie voles show strong pair bonding with their mating partners, and they demonstrate parental behavior toward their infants, indicating that the prairie vole is a unique animal model for analysis of molecular mechanisms of social behavior. Until a recent study, the signaling pathway of oxytocin was thought to be cr...

journal_title：Cell transplantation

authors： Katayama M,Hirayama T,Horie K,Kiyono T,Donai K,Takeda S,Nishimori K,Fukuda T

更新日期：2016-01-01 00:00:00

abstract：:Possible strategies for treating stroke include: 1) thrombolytic therapy with tissue plasminogen activator (tPA): restoring cerebral blood flow in the acute phase of ischemic stroke but sometimes causing hemorrhagic transformation (HT); 2) stem cell therapy: the repair of disrupted neuronal networks with newly born ne...

journal_title：Cell transplantation

authors： Yamashita T,Deguchi K,Nagotani S,Abe K

更新日期：2011-01-01 00:00:00

abstract：:The periodontal ligament displays a reservoir of mesenchymal stem cells which can account for periodontal regeneration. Despite the numerous studies directed at the definition of optimal culture conditions for long-term expansion of periodontal ligament stem cells (PDLSCs), no consensus has been reached as to what is ...

journal_title：Cell transplantation

authors： Di Vito A,Giudice A,Chiarella E,Malara N,Bennardo F,Fortunato L

更新日期：2019-01-01 00:00:00

abstract：:Previous observations in heat-shocked pig islets revealed the ambivalent character of the stress response simultaneously inducing processes of protection and apoptosis. To clarify whether the proapoptotic character of the stress response is reduced in heat-exposed islets still embedded in their native environment, hyp...

journal_title：Cell transplantation

authors： Brandhorst H,Olbrich M,Neumann A,Jahr H,Brandhorst D

更新日期：2007-01-01 00:00:00

abstract：:Pancreatic beta cell lines may offer an abundant source of cells for beta-cell replacement in type I diabetes. Using regulatory elements of the bacterial tetracycline (tet) operon for conditional expression of SV40 T antigen oncoprotein in transgenic mouse beta cells, we have shown that reversible immortalization is a...

journal_title：Cell transplantation

authors： Milo-Landesman D,Surana M,Berkovich I,Compagni A,Christofori G,Fleischer N,Efrat S

更新日期：2001-01-01 00:00:00

abstract：:Persistent corneal wounds result from numerous eye disorders, and to date, available treatments often fail to accelerate reepithelialization, the key initial step in wound healing. To speed reepithelialization, we explored a cell-transfer transplant method utilizing polydimethylsiloxane (PDMS) contact lenses to delive...

journal_title：Cell transplantation

authors： Pino CJ,Haselton FR,Chang MS

更新日期：2005-01-01 00:00:00

abstract：:Cell therapy is a promising treatment modality to improve heart function in acute myocardial infarction. However, the mechanisms of action and the most suitable cell type have not been finally determined. We performed a study to compare the effects of mesenchymal stem cells (MSCs) harvested from different tissues on ...

journal_title：Cell transplantation

authors： Otto Beitnes J,Oie E,Shahdadfar A,Karlsen T,Müller RM,Aakhus S,Reinholt FP,Brinchmann JE

更新日期：2012-01-01 00:00:00

abstract：:In this study the time course of homing and the body distribution of systemically delivered bone marrow mesenchymal stem cells (BM-MSCs) after myocardial infarction (MI) were evaluated. BM-MSCs were isolated from Wistar rats, expanded in vitro, and their phenotypical characterization was performed by flow cytometer. R...

journal_title：Cell transplantation

authors： Assis AC,Carvalho JL,Jacoby BA,Ferreira RL,Castanheira P,Diniz SO,Cardoso VN,Goes AM,Ferreira AJ

更新日期：2010-01-01 00:00:00

abstract：:A newly developed immunosuppressant, FTY720, has a unique mechanism that is quite different from those of conventional immunosuppressants, and is presumed to be mediated through decreases in the number of peripheral lymphocytes, especially helper T cells. This study was performed to ascertain whether this innovative d...

journal_title：Cell transplantation

authors： Yamasaki T,Inoue K,Hayashi H,Gu Y,Setoyama H,Ida J,Cui W,Kawakami Y,Kogire M,Imamura M

更新日期：1998-07-01 00:00:00

abstract：:The clinical consequences of acute liver failure are associated with high mortality. Intensive medical intervention is required to treat the symptoms of liver failure, including coagulopathy, metabolic instability, and encephalopathy. Providing temporary liver support with an extracorporeal liver assist device could s...

journal_title：Cell transplantation

authors： Gregory PG,Connolly CK,Toner M,Sullivan SJ

更新日期：2000-01-01 00:00:00

abstract：:New treatment paradigms that slow or reverse progression of chronic kidney disease (CKD) are needed to relieve significant patient and healthcare burdens. We have shown that a population of selected renal cells (SRCs) stabilized disease progression in a mass reduction model of CKD. Here, we further define the cellular...

journal_title：Cell transplantation

authors： Kelley R,Bruce A,Spencer T,Werdin E,Ilagan R,Choudhury S,Rivera E,Wallace S,Guthrie K,Jayo M,Xu F,Rao AN,Humphreys BD,Presnell S,Bertram T

更新日期：2013-01-01 00:00:00

abstract：:Procurement of multipotential neuroglial stem cells is possible with the addition of epidermal growth factor (EGF). Stem cells will differentiate into neurons and glia upon the removal of EGF from the culture medium. We have previously characterized the neuronal differentiation of stem cells derived from long-term cul...

journal_title：Cell transplantation

authors： Chiang YH,Silani V,Zhou FC

更新日期：1996-03-01 00:00:00

abstract：:Recent advances in tissue engineering technologies have highlighted the ability to create functional liver systems using isolated hepatocytes in vivo. Considering the serious shortage of donor livers that can be used for hepatocyte isolation, it has remained imperative to establish a hepatocyte propagation protocol t...

journal_title：Cell transplantation

authors： Ohashi K,Tatsumi K,Tateno C,Kataoka M,Utoh R,Yoshizato K,Okano T

更新日期：2012-01-01 00:00:00

abstract：:Rare cells are present in human umbilical cord blood that do not express the hematopoietic marker CD45 and in culture do not produce cells of hematopoietic lineage. These umbilical cord multipotent stem cells (UC-MC) behave as multilineage progenitor cells (stem cells) and can be expanded in tissue culture. Exposure t...

journal_title：Cell transplantation

authors： Bicknese AR,Goodwin HS,Quinn CO,Henderson VCD,Chien SN,Wall DA

更新日期：2002-04-01 00:00:00

abstract：:Human skin contains keratinocytes in the epidermis. Such cells share their ectodermal origin with the central nervous system (CNS). Recent studies have demonstrated that terminally differentiated somatic cells can adopt a pluripotent state, or can directly convert its phenotype to neurons, after ectopic expression of ...

journal_title：Cell transplantation

authors： Tenorio-Mina A,Cortés D,Esquivel-Estudillo J,López-Ornelas A,Cabrera-Wrooman A,Lara-Rodarte R,Escobedo-Avila I,Vargas-Romero F,Toledo-Hernández D,Estudillo E,Acevedo-Fernández JJ,Tapia JS,Velasco I

更新日期：2021-01-01 00:00:00

abstract：:To examine the effects of autologous sural nerve and adrenal medullary tissue intrastriatal cografts upon voluntary motor performance in parkinsonism, a non-human primate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) model was employed to quantitatively assess skilled hand movements. Motor performance was studie...

journal_title：Cell transplantation

authors： Watts RL,Mandir AS,Bakay RA

更新日期：1995-01-01 00:00:00

abstract：:Facioscapulohumeral muscular dystrophy (FSHD) is the third most frequent inherited myopathy. We previously demonstrated that mesoangioblasts can be efficiently isolated from FSHD muscles, although their differentiation ability into skeletal muscle was variably impaired. This correlates with overall disease severity a...

journal_title：Cell transplantation

authors： Morosetti R,Gidaro T,Broccolini A,Gliubizzi C,Sancricca C,Tonali PA,Ricci E,Mirabella M

更新日期：2011-01-01 00:00:00

abstract：:Early graft loss in islet transplantation means that a large amount of donor islets is required. Endothelial cells and endothelial colony-forming cells (ECFCs) have been reported to improve instant blood-mediated inflammatory reaction (IBMIR) in vitro. In this study, we examined if ECFC-coated porcine islets would pre...

journal_title：Cell transplantation

authors： Jung HS,Kim MJ,Hong SH,Lee YJ,Kang S,Lee H,Chung SS,Park JS,Park KS

更新日期：2014-03-01 00:00:00