Immunocompetence may be important in the effectiveness of Mectizan (ivermectin) in the treatment of human onchocerciasis.

Abstract:

:Mectizan (Ivermectin) has been proved to be central to the control of onchoceriasis through self-sustainable community-based treatment. The possibility of parasitological unresponsiveness to this treatment or selection for drug resistance has emerged recently in many occasions. The reason for the reduced ability of Mectizan to maintain low levels of dermal microfilariae and early recurrent pruritus can only be speculated upon. Here, we report our own findings to address this particular issue.

journal_name

Acta Trop

journal_title

Acta tropica

authors

Ali MM,Mukhtar MM,Baraka OZ,Homeida MM,Kheir MM,Mackenzie CD

doi

10.1016/s0001-706x(02)00117-1

subject

Has Abstract

pub_date

2002-10-01 00:00:00

pages

49-53

issue

1

eissn

0001-706X

issn

1873-6254

pii

S0001706X02001171

journal_volume

84

pub_type

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