Abstract:
:As the only specialized institution for research and control of parasitic diseases at the national level in China for almost 70 years, the National Institute of Parasitic Diseases (NIPD) at the Chinese Center for Disease Control and Prevention (China CDC) has been instrumental in supporting the remarkable progress from high prevalence to transmission interruption or low endemicity of several diseases, lymphatic filariasis, malaria and schistosomiasis in particular. This has taken place through technical guidance, emergency response and scientific research as well as providing technical service, education, training, health promotion and international cooperation. With China's increasing involvement in international cooperation and the increased risk for (re)emerging tropical diseases in mind, the Chinese Government designated in 2017 a new Chinese Center for Tropical Disease Research to NIPD. Responding to the expanded responsibilities, the institute is scaling up its activities in several ways: from parasitic diseases to the wider area of tropical diseases; from disease control to disease elimination; from biological research to policy evidences accumulation; and from public health to global health. Based on this new vision and China's previous accomplishments in the areas mentioned, the institute is in a position to move forward with respect to global health and equitable development according to the central principles of the United Nations' Sustainable Development Goals.
journal_name
Acta Tropjournal_title
Acta tropicaauthors
Chen J,Ding W,Li Z,Zhou DD,Yang P,Wang RB,Zheng B,Sheng HF,Guan YY,Xiao N,Li SZ,Zhou XNdoi
10.1016/j.actatropica.2019.105219subject
Has Abstractpub_date
2020-01-01 00:00:00pages
105219eissn
0001-706Xissn
1873-6254pii
S0001-706X(19)30743-0journal_volume
201pub_type
杂志文章,评审相关文献
ACTA TROPICA文献大全abstract::This study evaluated plant-based immune-adjuvants from crude extracts of Phoenix dactylifera and Mentha piperita as promising adjuvants for vaccines because of the limited side effects associated with plant extracts. In addition, Montanide™ ISA 201 previously used in vaccines in cattle. Eight different infectious cory...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2019.105281
更新日期:2020-02-01 00:00:00
abstract::We report a new endemic zone of cutaneous leishmaniasis (CL) in the central area of the State of Paraná (Municipality of Prudentópolis), in southern Brazil. This region was not previously considered endemic for CL, and this work constitutes the first report of CL endemicity there. Leishmaniasis was confirmed by smear,...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2009.05.013
更新日期:2009-09-01 00:00:00
abstract::Evidence for the phenomenon of multiple drug resistance (MDR) in the well studied pathogenic protozoa has been examined. This has been placed in the more familiar context of the MDR efflux transporters and the cloned mdr genes of mammalian cells. Homologues of the mdr gene family in protozoa and their possible role in...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/0001-706x(94)90063-9
更新日期:1994-03-01 00:00:00
abstract::Millions of people worldwide have a chronic infection with the liver fluke Opisthorchis felineus, which causes opisthorchiasis in humans and animals. The only known effective drug for this disease is praziquantel (PrzQ); however, its efficacy is below 100%, and it has some adverse effects. In this study, a water-solub...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2019.03.017
更新日期:2019-06-01 00:00:00
abstract::This review outlines the metabolism of polyamines in African trypanosomes and summarizes evidence to indicate that trypanosome polyamine metabolism differs in several important aspects from that of the mammalian host. These differences relate to the halflife, turnover, substrate specificity and regulation of enzymes w...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/0001-706x(93)90095-s
更新日期:1993-09-01 00:00:00
abstract::The effect of vaccines against the pre-erythrocytic, the erythrocytic and the sexual stages of malaria on the transmission of malaria was examined using a simulation model of seasonal or epidemic transmission. The primary outcome of the model was the number of cases of malaria present at the end of the transmission se...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/0001-706x(93)90013-2
更新日期:1993-01-01 00:00:00
abstract::Over the last 20 years a great advance has been observed in many aspects of medicine, and the advent of novel imaging techniques is certainly amongst the most important. In schistosomiasis these new methods caused a revolution in the definition of the clinical forms of the disease and in the evaluation of its complica...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/j.actatropica.2008.07.009
更新日期:2008-11-01 00:00:00
abstract::Giardiasis is a major problem in León, Nicaragua, yet despite this no data are available regarding the prevalence of different Giardia genotypes in this area. To address this question, a molecular analysis of Giardia isolates from humans and dogs living in the same area in León, Nicaragua was performed. Giardia isolat...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2008.01.004
更新日期:2008-04-01 00:00:00
abstract::The identification and characterization of Leishmania are relevant to diagnosis, treatment, eco-epidemiology studies, prophylactic measures and control of the disease. Two strains of Leishmania (MHOM/BR/1971/BH49 and MHOM/BR/1971/BH121), isolated from human cutaneous leishmaniasis, were studied using biological and mo...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2009.07.026
更新日期:2009-12-01 00:00:00
abstract::Studies on in vitro skin permeation and in vivo anti-leishmanial activity in mice experimentally infected with Leishmania (Leishmania) major pointed out to the potential of a new paromomycin (PA) formulation (hydrophilic gel) for treatment of cutaneous leishmaniasis (CL). In this study, the activity of this formulatio...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2004.10.007
更新日期:2005-02-01 00:00:00
abstract::We present data showing that structures serving as drains and catch basins for stormwater are important sources for production of the mosquito arbovirus vectors Aedes aegypti and Culex quinquefasciatus in Mérida City, México. We examined 1761 stormwater drains - located in 45 different neighborhoods spread across the ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2014.01.011
更新日期:2014-06-01 00:00:00
abstract::Chagas disease, caused by Trypanosoma cruzi affects about 6-8 million people worldwide. Although transmission by triatomine insects has been controlled, other means of transmission maintain the infection. These forms of transmission are responsible for introducing Chagas disease in other non-endemic countries of the w...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2017.08.025
更新日期:2017-12-01 00:00:00
abstract::Antibodies to the variable antigen type (VAT) designated LiTat 1.3 are common in sera from parasitologically confirmed patients with gambian sleeping sickness. For this reason, LiTat 1.3 has been considered a suitable antigen for detecting Trypanosoma brucei gambiense in the Card Agglutination Test for Trypanosomiasis...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/0001-706x(92)90054-2
更新日期:1992-06-01 00:00:00
abstract::Antigen-detection enzyme immunoassays (ELISA) were used for the diagnosis of Trypanosoma vivax, T. congolense and T. brucei in N'Dama cattle in Gabon, Central Africa. The assays are based on monoclonal antibodies which recognise trypanosome antigens specific for each of the three species and animals were termed 'antig...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/0001-706x(91)90068-u
更新日期:1991-11-01 00:00:00
abstract::A comparative study of egg morphology of Schistosoma mansoni carried out between 9 parasite populations from Guadeloupean foci demonstrates the existence of an intraspecific polymorphism. Three types of lateral spined eggs have been described and their relative proportions observed between populations are related to t...
journal_title:Acta tropica
pub_type: 杂志文章
doi:
更新日期:1986-12-01 00:00:00
abstract::Leishmania infantum is a protozoan that causes visceral leishmaniasis, a potentially deadly neglected tropical disease. The gold standard for diagnosis has traditionally been detection of amastigotes in bone marrow or spleen aspirates, but this is an invasive procedure that carries the risk of serious complications. N...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2017.12.011
更新日期:2018-02-01 00:00:00
abstract::Cryptosporidium is one of the most widespread protozoan parasites that infects domestic and wild animals and is considered the second major cause of diarrhea and death in children after rotavirus. So far, around 20 distinct species are known to cause severe to moderate infections in humans, of which Cryptosporidium ho...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/j.actatropica.2017.10.023
更新日期:2018-08-01 00:00:00
abstract::By standardized interviews of people in 23 rural villages, in the Oio region of Guinea Bissau, we collected data on which plant species and plant derived products or methods people use to reduce mosquito biting activity. The following plants were used to reduce numbers of mosquitoes indoors at night: fresh or smoulder...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(98)00083-7
更新日期:1999-01-15 00:00:00
abstract::Immune sera obtained from either BALB/c mice (susceptible) at 7 weeks, or C57BL/6 mice (resistant), at 7 weeks after infection with L. m. amazonensis, were effective in increasing internalization of homologous promastigotes into starch-induced peritoneal macrophages (from both mouse strains). Both the internalization ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:
更新日期:1987-09-01 00:00:00
abstract::Coxiellosis is a zoonotic disease caused by the ubiquitous bacteria Coxiella burnetii, which can be spread either through ticks or through body fluids. In humans the infection is characterized by a febrile disease; ruminants may abort and reduce their milk yield, causing serious production losses for the farmer. In In...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2019.03.022
更新日期:2019-06-01 00:00:00
abstract::In this study we standardized a new technical approach in which the target mitochondrial DNA sequence (mtDNA) is amplified using a simple but sensitive PCR method as a tool to detect Plasmodium falciparum and Plasmodium vivax. Specific primers were designed to hybridize with cytochrome c oxidase genes of P. falciparum...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2009.02.003
更新日期:2009-07-01 00:00:00
abstract::Several methods based on the detection of the parasite-specific pigment haemozoin (Hz) in blood are currently being investigated as alternative diagnostic methods for malaria. Although this approach may appear attractive, the fact that in Plasmodium falciparum (P. f.) malaria, the severity of which should give it the ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2012.03.005
更新日期:2012-07-01 00:00:00
abstract::In the present investigation, it has been demonstrated that cattle become resistant to ticks after several heavy infestations, particularly with B. microplus. During development of the infestations, antibodies against salivary glands of B. microplus were detected using 2 techniques: indirect immunofluorescence and imm...
journal_title:Acta tropica
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::Malaria in pregnancy is associated with increased risks of maternal anemia, spontaneous abortion, low birth weight, premature delivery and other adverse effects on health. In Brazil, disease transmission is highly concentrated in the multi-state region that constitutes the Brazilian Amazon (more than 99% of all cases)...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2012.11.004
更新日期:2013-02-01 00:00:00
abstract::Three Entamoeba spp. including E. suis, zoonotic E. polecki, and E. histolytica, have been described in pigs to date. However, little is known about the molecular epidemiology of these neglected parasites in pigs globally. In this study we surveyed the occurrence and molecular epidemiology of porcine Entamoeba spp. in...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2018.06.020
更新日期:2018-09-01 00:00:00
abstract::The formation of metacyclic trypomastigotes of Trypanosoma cruzi in cultures initiated by freshly isolated bloodstream trypomastigotes was studied using three strains of parasites (Peru, CL, and Y) and two different media (L-15 and Grace's medium). Serum (10% newborn calf serum) and various sugars were required for in...
journal_title:Acta tropica
pub_type: 杂志文章
doi:
更新日期:1983-06-01 00:00:00
abstract::The Japanese Encephalitis (JE) virus circulation in Indonesia was first documented in Lombok in 1960, and the virus was first isolated in 1972 from Culex tritaeniorhynchus in Bekasi, West Java and Kapuk, West Jakarta. Since then, Indonesia has been recognized as an endemic country for JE transmission. Up to now, JE ca...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/j.actatropica.2018.08.017
更新日期:2018-11-01 00:00:00
abstract::The levels of immunoglobulin classes (IgG, IgM and IgA) along with B lymphocyte population size were estimated in 24 kala-azar (KA) patients and results were compared with those obtained from 30 controls. A marked increase in the level of IgG and to a lesser extent in that of IgM was noted in the sera of KA patients. ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:
更新日期:1986-09-01 00:00:00
abstract::The polyamines, spermine and spermidine--organic polycations that are absolutely required for eukaryotic cell growth--are shown here to function in Trypanosoma cruzi epimastigotes, as protectors of membrane lipoperoxidation by reactive oxygen species generated either by H2O2/Fe2+ or nifurtimox. In vitro, spermine and ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/j.actatropica.2006.02.005
更新日期:2006-04-01 00:00:00
abstract::In July 1989, blood samples were collected from parasitaemic cattle in the Ghibe valley, Ethiopia, frozen in liquid nitrogen and transported to Nairobi, Kenya. Twelve of the stabilates were inoculated into individual Boran (Bos indicus) calves and characterised for their sensitivity, in turn, to diminazene aceturate (...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/0001-706x(93)90026-8
更新日期:1993-04-01 00:00:00