Abstract：
:Gut lectins of the insect vectors play important roles in the transmission of pathogens. Galactosamine, a sandfly midgut lectin inhibitor, was previously demonstrated to increase the intensity of Leishmania infection in sandflies; it was suggested that this was due to the inhibition of sandfly midgut lectin. However, galactosamine might also enhance Leishmania growth in the sandfly. Therefore, the aim of this work was to study the effect of galactosamine and other carbohydrates on Leishmania in vitro. At 50 mM concentration, galactosamine inhibits growth of promastigotes, at 10 mM it induces morphological changes similar to that seen in infected sandflies. Glucosamine effect is less pronounced, galactose has no effect. This suggests that the effect of galactosamine on Leishmania differs in vivo and in vitro. Thus, galactosamine does not enhance Leishmania development in sandflies directly, but rather interferes with some aspect of sandfly physiology (e.g. proteinase and/or lectin activity).
journal_name
Acta Tropjournal_title
Acta tropicaauthors
Svobodová Mdoi
10.1016/s0001-706x(00)00105-4subject
Has Abstractpub_date
2000-10-02 00:00:00pages
285-8issue
3eissn
0001-706Xissn
1873-6254pii
S0001706X00001054journal_volume
76pub_type
杂志文章相关文献
ACTA TROPICA文献大全abstract：:Field experiments were conducted in central Kenya, to study the effect of ammonium sulphate fertiliser ((NH(4))(2)SO(4)) on mosquito larval populations in rice fields. The experiments used a complete randomised block design having four blocks with two experimental ponds per block, and the fertiliser and control treatm...
journal_title：Acta tropica
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.actatropica.2003.08.006
更新日期：2004-01-01 00:00:00
abstract：:Chagas disease is a major unsolved health issue in Latin America and an emerging threat worldwide. New drugs are urgently needed for chemotherapy as those available (benznidazole and nifurtimox) have variable efficacy and elevated toxicity. Efforts are actually oriented to improve tools and technologies (e.g. transgen...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2015.08.004
更新日期：2015-12-01 00:00:00
abstract：:The effect of concomitant infection with schistosomes, Plasmodium falciparum and soil transmitted helminths (STHs) on anaemia was determined in 609 Zimbabwean primary school children. P. falciparum, haemoglobin levels and serum ferritin were determined from venous blood. Kato Katz, formal ether concentration and urine...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2010.02.010
更新日期：2010-07-01 00:00:00
abstract：:Disease control programmes are an intrinsic part of health systems. Neglected tropical disease (NTD) control is a clear case in point. While there is a growing consensus that NTD control and health services are linked, with important mutual impacts, little is known of what actually happens at the interface between the...
journal_title：Acta tropica
pub_type： 杂志文章,评审
doi：10.1016/j.actatropica.2011.02.017
更新日期：2011-09-01 00:00:00
abstract：:The London School of Tropical Medicine, and indeed the 'new' discipline of tropical medicine, originated in 1899 at the Albert Dock Hospital - situated in London's east-end. The founder of the discipline was Patrick Manson - with a great deal of political assistance from the British Secretary of State for the Colonies...
journal_title：Acta tropica
pub_type： 历史文章,杂志文章
doi：10.1016/s0001-706x(01)00127-9
更新日期：2001-06-22 00:00:00
abstract：:Anopheles annularis is one of the major vectors of malaria in Odisha, India. The present study was undertaken to determine the vectorial capacity and assess the genetic diversity of An. annularis collected from different endemic regions of Odisha. Mosquitoes were collected from thirteen endemic districts using standar...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2014.05.002
更新日期：2014-09-01 00:00:00
abstract：:Antibodies to the variable antigen type (VAT) designated LiTat 1.3 are common in sera from parasitologically confirmed patients with gambian sleeping sickness. For this reason, LiTat 1.3 has been considered a suitable antigen for detecting Trypanosoma brucei gambiense in the Card Agglutination Test for Trypanosomiasis...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/0001-706x(92)90054-2
更新日期：1992-06-01 00:00:00
abstract：:The geographical distribution of snail (i.e., the intermediate host of schistosomiasis) is consistent with that of endemic areas. The suitable snail habitus requires necessary environmental conditions for snail population. The high-resolution remote sensing provides an important tool for the spatio-temporal analysis o...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2019.105077
更新日期：2019-10-01 00:00:00
abstract：:While Burkholderia pseudomallei, the causative agent of melioidosis, is becoming increasingly recognized as a significant cause of morbidity and mortality in regions to which it is endemic, no licensed vaccine preparation currently exists for immunization against the disease. Therefore, one of the primary goals of our...
journal_title：Acta tropica
pub_type： 杂志文章,评审
doi：10.1016/s0001-706x(99)00071-6
更新日期：2000-02-05 00:00:00
abstract：:Entomopathogenic fungi, especially Metarhizium anisopliae, have potential for integrated control of peridomestic triatomine bugs. However, the high susceptibility of these vectors to fungal infection at elevated ambient humidities decreases in the comparatively dry conditions that often prevail in their microhabitats....
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2011.11.014
更新日期：2012-04-01 00:00:00
abstract：:In this work the effect of a novel compound, 5-epi-icetexone (ICTX) obtained from Salvia gilliessi Benth. (Labiatae), is studied on cultured epimastigotes of Trypanosoma cruzi (Tulahuen). It was found that the compound exerts an antiproliferative effect on the parasites at concentrations between 2.8 and 4.2 microM, an...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2005.12.007
更新日期：2006-05-01 00:00:00
abstract：:In Mizoram, the origin and molecular nature of Anopheles species is poorly understood, despite the region having high malarial incidence and rich biodiversity. A diagnostic PCR assay for distinguishing the Cellia subgenera members of Anopheles species was developed based on the interspecific ITS2 variation. No intrasp...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2012.12.001
更新日期：2013-03-01 00:00:00
abstract：:Although long considered a non-pathogenic protozoan, Giardia lamblia is now a well recognized cause of abdominal discomfort, diarrhoea and failure-to-thrive in children. The overall prevalence of this infection in Cuban population is about 7.2%; however, higher prevalences have been found among young children attendin...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2011.04.014
更新日期：2011-08-01 00:00:00
abstract：:The aim of the study was to evaluate the temporal patterns of dengue incidence from 2001 to 2014 and forecast for 2015 in two Brazilian cities. We analysed dengue surveillance data (SINAN) from Recife, 1.6 million population, and Goiania, 1.4 million population. We used Auto-Regressive Integrated Moving Average (ARIMA...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2018.03.006
更新日期：2018-06-01 00:00:00
abstract：:The study aimed to establish if there was any relationship between the blood group of the human host and schistosomiasis prevalence, intensity, incidence and related organ pathology. Urine and stool specimens were collected from the 735 school children attending a rural school in Zimbabwe to determine the Schistosoma ...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/s0001-706x(97)00671-2
更新日期：1997-05-30 00:00:00
abstract：:The information in this protocol covers from the basic steps and material necessary to start a sand fly colony up to the specific details which are important to the success of a Nyssomyia neivai colony. The greatest problems in our colony of Ny. neivai were solved with specific care, for instance, using vermiculite an...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2017.07.010
更新日期：2017-10-01 00:00:00
abstract：:The objective of this study was to investigate paraoxonase-1 (PON1) activity, cortisol levels, and the lipid profile in the sera of alcoholic and non-alcoholic Strongyloides stercoralis-infected and uninfected individuals in a sample of 276 individuals attended at the National Health System in Salvador, Bahia, Brazil....
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2016.10.013
更新日期：2017-02-01 00:00:00
abstract：:In the present study for the first time an alternative definitive host model has been established for the complete development of Echinococcus granulosus in Meriones unguiculatus (Mongolian gerbils) up to shelled eggs production, as happened in the natural host. Animals treated with methylprednisolone acetate were ora...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2005.08.009
更新日期：2006-02-01 00:00:00
abstract：:This study evaluated plant-based immune-adjuvants from crude extracts of Phoenix dactylifera and Mentha piperita as promising adjuvants for vaccines because of the limited side effects associated with plant extracts. In addition, Montanide™ ISA 201 previously used in vaccines in cattle. Eight different infectious cory...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2019.105281
更新日期：2020-02-01 00:00:00
abstract：:Microtus fortis is a naturally resistant vertebrate host of Schistosoma japonicum by preventing completion of parasite's life cycle. Sera of M. fortis were found to have anti-schistosome effect in vitro and in vivo. In order to identify genes associated with the anti-schistosome effect of M. fortis, we screened a M. f...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2010.03.007
更新日期：2010-09-01 00:00:00
abstract：:Studies on in vitro skin permeation and in vivo anti-leishmanial activity in mice experimentally infected with Leishmania (Leishmania) major pointed out to the potential of a new paromomycin (PA) formulation (hydrophilic gel) for treatment of cutaneous leishmaniasis (CL). In this study, the activity of this formulatio...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2004.10.007
更新日期：2005-02-01 00:00:00
abstract：:Human visceral (VL, also known as Kala-azar) and cutaneous (CL) leishmaniasis are important infectious diseases affecting countries in East Africa that remain endemic in several regions of Ethiopia. The transmission and epidemiology of the disease is complicated due to the complex life cycle of the parasites and the i...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2015.02.006
更新日期：2015-05-01 00:00:00
abstract：:African horse sickness- and bluetongue virus are orbiviruses transmitted by Culicoides biting midges (Diptera: Ceratopogonidae) to horses and to ruminants, respectively. Since the last epizootic outbreak of African horse sickness in 2007 in Senegal, extensive investigations have been undertaken to improve our knowledg...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2015.06.012
更新日期：2015-09-01 00:00:00
abstract：:The prevalence and associated risk factors for Giardia duodenalis in canine and human populations in Temple communities of Bangkok, Thailand were determined by evaluating three common diagnostic methods utilised to detect Giardia, namely zinc sulphate flotation and microscopy, an immunofluoresence antibody test and ne...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2009.03.006
更新日期：2009-08-01 00:00:00
abstract：:We compared age-related seroprevalence of Trypanosoma cruzi infection with history of vector control interventions and social and ecological changes in three historically endemic departments of Cordoba province, Argentina, covering an area of 42,600 km(2) of the Gran Chaco region. Using a cross sectional design, blood...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2009.11.007
更新日期：2010-03-01 00:00:00
abstract：:We aimed to systematically review evidence pertaining to the safety and efficacy of nitazoxanide in treating infectious diarrhea. On September 21, 2017, we identified relevant studies using 12 databases. The estimates of the included studies were pooled as a risk ratio (RR). We conducted a network and pairwise random-...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2020.105603
更新日期：2020-10-01 00:00:00
abstract：:Erythrocyte survival was studied in 17 Thai patients (10 males, 7 females; aged 13-57 years) with severe falciparum malaria. To ensure radioisotopic labelling of cells before bone marrow recovery and survival analysis under near-steady state conditions, 51Cr labelling of autologous erythrocytes was performed at the ti...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/0001-706x(91)90014-b
更新日期：1991-02-01 00:00:00
abstract：:Mosquito-borne diseases affect millions of individuals worldwide; the area of endemic transmission has been increasing due to several factors linked to globalization, urban sprawl, and climate change. The Aedes aegypti mosquito plays a central role in the dissemination of dengue, Zika, chikungunya, and urban yellow fe...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2020.105398
更新日期：2020-05-01 00:00:00
abstract：:By standardized interviews of people in 23 rural villages, in the Oio region of Guinea Bissau, we collected data on which plant species and plant derived products or methods people use to reduce mosquito biting activity. The following plants were used to reduce numbers of mosquitoes indoors at night: fresh or smoulder...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/s0001-706x(98)00083-7
更新日期：1999-01-15 00:00:00
abstract：:The effect of vaccines against the pre-erythrocytic, the erythrocytic and the sexual stages of malaria on the transmission of malaria was examined using a simulation model of seasonal or epidemic transmission. The primary outcome of the model was the number of cases of malaria present at the end of the transmission se...
journal_title：Acta tropica
pub_type： 杂志文章,评审
doi：10.1016/0001-706x(93)90013-2
更新日期：1993-01-01 00:00:00
