Abstract：
:In the present study for the first time an alternative definitive host model has been established for the complete development of Echinococcus granulosus in Meriones unguiculatus (Mongolian gerbils) up to shelled eggs production, as happened in the natural host. Animals treated with methylprednisolone acetate were orally inoculated with approximately 3000 protoscoleces and the development of parasites in the small intestine observed up to 46 days post-infection (p.i.). The cestodes survive, strobilate, mature sexually and complete their development in the intestine up to production of shelled embryonated eggs containing fully formed six-hooked oncospheres, similarly to the natural canid host (stage 7 by Smyth). Shelled eggs are first observed in the rodent/E. granulosus model at 44 days p.i. Somatic growth in gerbils appears to follow a similar trend to dogs, length increasing to over 3mm at 44 days p.i., while, compared to the natural host, organogenesis is observed only to progress at a slower rate in the early developmental stages. Parasite burden was found to vary among non-inbred animals and developmental stages of worms recovered from the same animal differed widely. Worm localisation follows the pattern observed in the natural host, the parasites appearing for the most part distributed in the proximal third of the small intestine. The development of alternative definitive hosts may facilitate research in this field, overcoming legislative impediments that restrict the use of dogs for experimental purposes.
journal_name
Acta Tropjournal_title
Acta tropicaauthors
Conchedda M,Gabriele F,Bortoletti Gdoi
10.1016/j.actatropica.2005.08.009subject
Has Abstractpub_date
2006-02-01 00:00:00pages
119-25issue
2eissn
0001-706Xissn
1873-6254pii
S0001-706X(05)00328-1journal_volume
97pub_type
杂志文章相关文献
ACTA TROPICA文献大全abstract：:A study of host preference in tsetse flies using a modified heteroduplex PCR-based method is described. Domestic and wild animal blood samples were collected to extract the corresponding reference DNAs. In Campo (south Cameroon), tsetse flies (mainly Glossina palpalis palpalis) were trapped and 41 bloodmeals were coll...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2004.03.006
更新日期：2004-07-01 00:00:00
abstract：:Malaria is one of the major causes of morbidity and mortality worldwide. The major factor which has aggravated the situation is the emergence of multidrug resistant Plasmodium falciparum malaria. To successfully deal with the problem, thorough understanding of the molecular bases for reduced parasite sensitivity to ex...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2009.10.016
更新日期：2010-02-01 00:00:00
abstract：:Homogenates of different developmental stages of the filarial parasites, L. carinii, emulsified in Freund's complete adjuvant have been examined for their efficacy in conferring immunity to the infection in the albino rats. The results revealed that sonicated preparations of microfilariae and infective larvae induce h...
journal_title：Acta tropica
pub_type： 杂志文章
doi：
更新日期：1981-09-01 00:00:00
abstract：:The Fast Agglutination Screening Test (FAST) was employed on sera obtained from an endemic area of visceral leishmaniasis in southwestern Ethiopia, in February 2000. The study involved (i) active case detection among 1575 residents of two villages; and (ii) passive case detection in an outpatient clinic. Sera of 1587 ...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/s0001-706x(02)00063-3
更新日期：2002-08-01 00:00:00
abstract：:The increasing spread of multi-drug resistant malaria in African highlands has highlighted the importance of malaria suppression through vector control. Its historical success has meant that larval control has been proposed as part of an integrated malaria vector control program. Due to high operation costs, larval co...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2011.04.003
更新日期：2011-07-01 00:00:00
abstract：:The trypanocidal activity of two commercially available isometamidium-based products, Samorin (Merial, USA) and Veridium (Sanofi Santé Nutrition Animale, France), used at a dose rate of 0.5 mg kg(-1) bodyweight, was compared in a field trial involving groups of approximately 30 zebu cattle in a trypanosomosis endemic ...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/s0001-706x(00)00132-7
更新日期：2000-11-02 00:00:00
abstract：:We focused on the epidemiology of alveolar echinococcosis especially in Japan and discussed control measures to prevent an epidemic. No effective control measures against alveolar echinococcosis have been identified thus far because it is difficult to fully understand the ecology of the parasite and its hosts, i.e. th...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2003.09.001
更新日期：2003-12-01 00:00:00
abstract：:In this study, Aphanius chantrei's behaviour of feeding on mosquito larvae has been determined under experimental conditions. In groups that have different sizes (first group 27 mm; second group 40 mm; third group 47 mm), larvae consumption has increased with length and weight. During daytime, average larvae consumpti...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2007.04.016
更新日期：2007-06-01 00:00:00
abstract：:In this study, 27 CDC traps were modified with various attractive features and compared with a CDC trap with no light source or baits to evaluate the effects on attraction to Phlebotomus papatasi (Scopoli) north of the Dead Sea near Jericho. Attractive features included CO2, lights, colored trap bodies, heat, moisture...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2014.06.007
更新日期：2015-01-01 00:00:00
abstract：:Brucellosis is caused by the genus Brucella. Brucella is widely distributed in cattle, swine, sheep, goat and other mammals including human. Animal brucellosis causes severe economic losses and affects related international transportation and trade. Human brucellosis causes both acute and chronic symptoms of multi-org...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2019.05.017
更新日期：2019-09-01 00:00:00
abstract：:The effect of vaccines against the pre-erythrocytic, the erythrocytic and the sexual stages of malaria on the transmission of malaria was examined using a simulation model of seasonal or epidemic transmission. The primary outcome of the model was the number of cases of malaria present at the end of the transmission se...
journal_title：Acta tropica
pub_type： 杂志文章,评审
doi：10.1016/0001-706x(93)90013-2
更新日期：1993-01-01 00:00:00
abstract：:Rodents are well-known hosts of Trypanosoma cruzi but little is known on the role of some caviomorph rodents. We assessed the occurrence and prevalence of T. cruzi infection in Microcavia australis ("southern mountain, desert or small cavy") and its infectiousness to the vector Triatoma infestans in four rural communi...
journal_title：Acta tropica
pub_type： 杂志文章,多中心研究
doi：10.1016/j.actatropica.2014.10.019
更新日期：2015-02-01 00:00:00
abstract：:The Clean India Mission is a national campaign that aims for complete elimination of open defecation from the country. In India, 564 million people do not have access to toilets and defecate in the open environment. The 'Millennium development goals' have given increased weightage to elimination of open defecation for...
journal_title：Acta tropica
pub_type： 杂志文章,评审
doi：10.1016/j.actatropica.2018.06.024
更新日期：2018-10-01 00:00:00
abstract：:Schistosomiasis of the lower female reproductive tract manifests itself in a broad spectrum of clinical features. However, clinical and histopathological findings have never been studied in a synoptic manner. Based on the assumption that any type of pathology present in the female reproductive tract is the expression ...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/s0001-706x(96)00027-7
更新日期：1996-12-30 00:00:00
abstract：:The aim of the study was to evaluate the temporal patterns of dengue incidence from 2001 to 2014 and forecast for 2015 in two Brazilian cities. We analysed dengue surveillance data (SINAN) from Recife, 1.6 million population, and Goiania, 1.4 million population. We used Auto-Regressive Integrated Moving Average (ARIMA...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2018.03.006
更新日期：2018-06-01 00:00:00
abstract：:Human cytochrome P450 2C8 is a highly polymorphic gene and shows variation according to ethnicity. The CYP2C8*2 is a slow drug metabolism allele and shows 10-24% frequency in Black populations. The objective of this study was to assess the prevalence of CYP2C8*2 allele in Botswana among the San (or Bushmen) and the Ba...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2016.01.028
更新日期：2016-05-01 00:00:00
abstract：:Chagas disease, caused by Trypanosoma cruzi affects about 6-8 million people worldwide. Although transmission by triatomine insects has been controlled, other means of transmission maintain the infection. These forms of transmission are responsible for introducing Chagas disease in other non-endemic countries of the w...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2017.08.025
更新日期：2017-12-01 00:00:00
abstract：:Microorganisms harbored by Chilean autochthonous ticks have been scarcely studied and current knowledge is restricted to three species of hard ticks only. The current study aimed to assess the presence of Anaplasmataceae, Borrelia and Hepatozoon agents in ticks collected directly from the environment, on reptiles, bir...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2019.02.002
更新日期：2019-04-01 00:00:00
abstract：:The several steps in the pathway for the biosynthesis of fibrillar collagen are reviewed to illustrate potential sites for the chemotherapeutic control of fibrosis. Particular emphasis is placed upon the properties and inhibition of lysyl oxidase, the enzyme which initiates the covalent crosslinking of extracellular c...
journal_title：Acta tropica
pub_type： 杂志文章,评审
doi：10.1016/s0001-706x(00)00128-5
更新日期：2000-10-23 00:00:00
abstract：:The drawback of existing techniques for obtaining intact granulomas and granuloma cells have been, (1) lack of clean intact granulomas without adhering liver tissues, (2) isolating inadequate numbers of clean intact granulomas, and (3) obtaining low numbers of viable granuloma cells from the granulomas. This work aims...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/s0001-706x(98)00034-5
更新日期：1998-06-30 00:00:00
abstract：:The geographical distribution of snail (i.e., the intermediate host of schistosomiasis) is consistent with that of endemic areas. The suitable snail habitus requires necessary environmental conditions for snail population. The high-resolution remote sensing provides an important tool for the spatio-temporal analysis o...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2019.105077
更新日期：2019-10-01 00:00:00
abstract：:This study aimed to investigate the prevalence of cercarial infections in freshwater snails collected from the Chai Nat province of Central Thailand. Moreover, we aimed to develop a duplex PCR technique, using the ITS2 and candidate MT-ND1 gene, to determine the dissemination of H. taichui and H. pumilio, respectively...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2020.105795
更新日期：2020-12-10 00:00:00
abstract：:Cattle were exposed to natural trypanosome challenge in an area of high Glossina density (Samandéni, Burkina Faso) for various periods of time during 1982, 1983, 1984 and 1985. All of 30 Zebu proved to be sensitive to trypanosomiasis i.e. they died or were treated in extremis in 10 +/- 4 weeks. Twenty-one (31%) Baoulé...
journal_title：Acta tropica
pub_type： 杂志文章
doi：
更新日期：1987-03-01 00:00:00
abstract：:Visceral leishmaniasis (VL) is a serious and widespread parasitic disease caused by Leishmania donovani complex. The threat of this fatal disease continues due to the lack of ideal drugs or vaccines. In this study, we selected Amastin, CaNA2, Kmp-11 and PDI proteins of Leishmania donovani for study, which are VL vacci...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2018.12.035
更新日期：2019-03-01 00:00:00
abstract：:The antidiarrhoeal effects of the methanol extract of Zizyphus spina-christi stem bark were evaluated in laboratory rodents. Studies on castor oil induced diarrhoea, intraluminal fluid accumulation, and gastrointestinal transit time were carried out. Results obtained revealed that the extract caused a dose dependent p...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/s0001-706x(03)00114-1
更新日期：2003-07-01 00:00:00
abstract：:Litomosoides carinii microfilariae were exsheathed by freezing and thawing, and the sheaths were separated by filtration. Samples of pure sheaths thus obtained were hydrolyzed, methanolyzed or oxidized with nitric acid under pressure at 300 degrees C, respectively, and were analyzed for amino acids, sugars, fatty acid...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/0001-706x(92)90080-h
更新日期：1992-02-01 00:00:00
abstract：:In accordance with international targets, the Uganda National Malaria Control Strategic Plan established specific targets to be achieved by 2010. For children under five, this included increasing the number of children sleeping under mosquito nets and those receiving a first-line antimalarial to 85%, and decreasing ca...
journal_title：Acta tropica
pub_type： 杂志文章,评审
doi：10.1016/j.actatropica.2015.07.028
更新日期：2015-12-01 00:00:00
abstract：:The surface coat of the protozoan parasite Leishmania affords remarkable protection in the harsh environments encountered within the insect vectors and vertebrate hosts. It also provides specificity for the interaction of these parasites with the cells in the sandfly gut and with the human macrophage. Surprisingly few...
journal_title：Acta tropica
pub_type： 杂志文章,评审
doi：10.1016/0001-706x(93)90029-b
更新日期：1993-05-01 00:00:00
abstract：:Bait-trapping is a useful approach for monitoring fly population dynamics, and it is an effective tool for physical control of pest species. The aim of this study was to test a newly developed semi-automatic funnel fly trap with some modifications of the former prototype fly trap to study medically important fly popul...
journal_title：Acta tropica
pub_type： 杂志文章
doi：10.1016/j.actatropica.2017.07.018
更新日期：2017-12-01 00:00:00
abstract：PURPOSE:Direct transmission of mutated tuberculosis (TB) strains is among major contributors to the worldwide epidemic of Drug-Resistant Tuberculosis. Expanding access to TB-services and decreasing diagnostic delays are acknowledged as potential solutions. We aimed to summarize evidence about links between health care ...
journal_title：Acta tropica
pub_type： 杂志文章,评审
doi：10.1016/j.actatropica.2016.06.014
更新日期：2016-09-01 00:00:00
