Abstract：
:The objective of this study was to investigate paraoxonase-1 (PON1) activity, cortisol levels, and the lipid profile in the sera of alcoholic and non-alcoholic Strongyloides stercoralis-infected and uninfected individuals in a sample of 276 individuals attended at the National Health System in Salvador, Bahia, Brazil. The activity of PON1 was measured by the Beltowski method, serum lipids, and cortisol levels using commercial kits. PON1 activity was low in both alcoholic and non-alcoholic individuals infected with S. stercoralis. A positive correlation was observed between PON1 activity and cortisol concentration in alcoholic individuals who were not infected with S. stercoralis; whereas a negative correlation occurred in S. stercoralis-infected nonalcoholic individuals. The levels of triglycerides, LDL-C, and VLDL-C in S. stercoralis-infected alcoholic individuals were significantly lower than in uninfected alcoholic individuals. The high level of HDL-C and the low level of LDL-C, VLDL, triglycerides and PON1 activity in alcoholic patients infected with S. stercoralis evidenced an anti-atherogenic pattern.
journal_name
Acta Tropjournal_title
Acta tropicaauthors
de Jesus Inês E,Sampaio Silva ML,de Souza JN,Galvão AA,Aquino Teixeira MC,Soares NMdoi
10.1016/j.actatropica.2016.10.013subject
Has Abstractpub_date
2017-02-01 00:00:00pages
1-6eissn
0001-706Xissn
1873-6254pii
S0001-706X(16)30463-6journal_volume
166pub_type
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