Abstract：
:We examined the malaria situation among 489 children under 5 years of age in the rural villages of Aboh Mbaise, Nigeria, using a combination of a standard questionnaire technique and laboratory diagnosis to confirm clinical observations. The results show a high prevalence rate of 52.8% for Plasmodium falciparum in this area. The geometric mean parasite density (GMPD) was 19,361.4/mm3. The proportion of children with fever and/or parasitaemia was not related to age, although the numbers in the febrile group appeared to increase with age. Using 37.5 degrees C as the threshold for fever, 48.7% of the heavily infected group (more than 1000/mm3) were afebrile while 51.3% were febrile. High grade temperatures above 38 degrees C were associated with high parasitaemia above 10,000 parasites/mm3. Of the 911 children who died in the area within the last five years, 22.4% died of fever of unknown origin, 39.7% from malaria, 22.5% from convulsion, 10.5% from diarrhoea and 4.6% from cough. Chloroquine is the drug of choice for the treatment of malaria and there were many cases of drug abuse, and use of sub-curative doses prescribed by non-medically qualified staff.
journal_name
Acta Tropjournal_title
Acta tropicaauthors
Ejezie GC,Ezedinachi EN,Usanga EA,Gemade EI,Ikpatt NW,Alaribe AAdoi
10.1016/0001-706x(90)90061-4subject
Has Abstractpub_date
1990-10-01 00:00:00pages
17-24issue
1eissn
0001-706Xissn
1873-6254pii
0001-706X(90)90061-4journal_volume
48pub_type
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