Inverse correlation of plasma leptin and soluble transferrin receptor levels in beta-thalassemia patients.

abstract：:Primary mediastinal large B cell lymphomas (MLCL) differ from other diffuse large cell lymphomas, leading to a description as a separate entity in the current World Health Organization classification. Dose intensification improves long-term results, but no standard therapy has been established so far. We investigated ...

journal_title：Annals of hematology

authors： Fietz T,Knauf WU,Hänel M,Franke A,Freund M,Thiel E,East German Study Group on Hematology and Oncology-OSHO.

更新日期：2009-05-01 00:00:00

abstract：:Relapse remains one of the major obstacles in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) even after allogeneic hematopoietic stem cell transplantation. The persistence of leukemia-propagating cells (LPCs) may lead to the recurrence of Ph+ALL. Using a xenograft assay, LPCs enrichment in the ...

journal_title：Annals of hematology

authors： Zhao HY,Song Y,Cao XN,Qin YZ,Lai YY,Jiang H,Jiang Q,Huang XJ,Kong Y

更新日期：2018-05-01 00:00:00

abstract：:In the context of discussions on the reproducibility of clinical studies, we reanalyzed a prospective randomized study on the role of splenic irradiation as adjunct to the conditioning for hematopoietic stem cell transplantation (HSCT) for chronic myeloid leukemia (CML). Between 1986 and 1989, a total of 229 patients ...

journal_title：Annals of hematology

authors： Gratwohl A,Iacobelli S,Bootsman N,van Biezen A,Baldomero H,Arcese W,Arnold R,Bron D,Cordonnier C,Ernst P,Ferrant A,Frassoni F,Gahrton G,Richard C,Kolb HJ,Link H,Niederwieser D,Ruutu T,Schattenberg A,Schmitz N,Torr

更新日期：2016-05-01 00:00:00

abstract：:Aberrant promoter methylation of RASSF6 and RASSF10 occurs at a high frequency in acute lymphoblastic leukemia (ALL). Because of the complexity of the current minimal residual disease (MRD) detecting-methods, the DNA methylation status of the RASSF6 and RASSF10 genes could potentially become biomarkers for the assessm...

journal_title：Annals of hematology

authors： Younesian S,Shahkarami S,Ghaffari P,Alizadeh S,Mehrasa R,Ghaffari SH

更新日期：2019-12-01 00:00:00

abstract：:Nodal peripheral T cell lymphomas (nPTCL) present aggressive clinical course, and its heterogeneous nature and poor prognosis with current therapeutic strategies make it a target for the development of new prognostic markers. Thus, we investigated tumor-associated macrophages (TAM) according to the number of cells exp...

journal_title：Annals of hematology

authors： de Pádua Covas Lage LA,Hamasaki DT,Moreira FR,Rocha V,Zerbini MCN,Pereira J

更新日期：2019-09-01 00:00:00

abstract：:In spite of their recognized risk of thrombosis, patients with myeloproliferative neoplasms (MPN) show little or no abnormalities of traditional coagulation tests, perhaps because these are unable to represent the balance between pro- and anticoagulants nor the effect of platelets and blood cells. We investigated whet...

journal_title：Annals of hematology

authors： Tripodi A,Chantarangkul V,Gianniello F,Clerici M,Lemma L,Padovan L,Gatti L,Mannucci PM,Peyvandi F

更新日期：2013-12-01 00:00:00

abstract：:Cytokines and adhesion molecules play an important role in the pathophysiology of vaso-occlusion in sickle cell disease (SCD), and their in vivo profiles are potential tools for assessing SCD severity. We compared steady-state soluble vascular cell adhesion molecule-1 (sVCAM-1) serum levels to clinical (painful crisis...

journal_title：Annals of hematology

authors： Schnog JB,Rojer RA,Mac Gillavry MR,Ten Cate H,Brandjes DPM,Duits AJ

更新日期：2003-02-01 00:00:00

abstract：:Genes involved in the hemostatic mechanism are logical candidate genes for association studies in prothrombotic conditions such as stroke. Since the underlying etiology in pediatric strokes is different than adults, looking for genetic causes would be the logical thing to do in the pediatric stroke population. Fifty-e...

journal_title：Annals of hematology

authors： Biswas A,Tiwari AK,Ranjan R,Meena A,Akhter MS,Yadav BK,Behari M,Saxena R

更新日期：2009-05-01 00:00:00

abstract：:Follicular lymphoma (FL) is generally considered an indolent disorder. With modern day treatments, long remissions are often achieved both in the front-line and relapsed setting. However, a subset of patients has a more aggressive course and a worse outcome. Their identification is the main purpose of modern day progn...

journal_title：Annals of hematology

authors： Sorigue M,Sancho JM

更新日期：2018-02-01 00:00:00

abstract：:Gastrointestinal graft-versus-host disease (GVHD) is one of the main causes of therapy-related death after allogeneic hemopoietic stem cell transplantation. Early diagnosis and immediate treatment are probably essential for improving clinical outcome. High-resolution sonography allows the evaluation of single bowel wa...

journal_title：Annals of hematology

authors： Görg C,Wollenberg B,Beyer J,Stolte MS,Neubauer A

更新日期：2005-01-01 00:00:00

abstract：:Secondary central nervous system (CNS) involvement in diffuse large B-cell lymphoma (DLBCL) includes an isolated CNS relapse or CNS involvement with systemic disease progression. This rare but fatal clinical problem still remains a therapeutic dilemma in the management of DLBCL. However, there are limited data about i...

journal_title：Annals of hematology

authors： Kim SJ,Oh SY,Kim JS,Kim H,Lee GW,Won JH,Shin HJ,Yang DH,Choi CW,Park J,Kim WS,Suh C

更新日期：2011-05-01 00:00:00

abstract：:Arsenic trioxide (As2O3) is a highly effective agent in the treatment of acute promyelocytic leukemia (APL), whereas other hematopoietic tumors are less responsive to this agent and mechanisms underlying As2O3,-resistance are poorly understood. To better understand the complex network of GSH-related pathways in As2O3 ...

journal_title：Annals of hematology

authors： Bernardini S,Nuccetelli M,Noguera NI,Bellincampi L,Lunghi P,Bonati A,Mann K,Miller WH Jr,Federici G,Lo Coco F

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Low folate intake and changes in folate metabolism due to polymorphisms in the methylentetrahydrofolate reductase (MTHFR) gene have been associated with myelomagenesis. However, controversial data have been published regarding a protective role of variant alleles of MTHFR on MM. PATIENTS AND METHODS:To inve...

journal_title：Annals of hematology

authors： Chiusolo P,Farina G,Putzulu R,Reddiconto G,Fiorini A,De Stefano V,Rossi E,Palladino M,Leone G,Sica S

更新日期：2006-07-01 00:00:00

abstract：:Circulating homocysteine is a risk factor of cardiovascular and cerebrovascular events. Hyperhomocysteinemia may be an early indicator for vitamin B12 disorders because cobalamin is a cofactor in the remethylation process of homocysteine. Serum holotranscobalamin (holoTC II) becomes decreased before the development of...

journal_title：Annals of hematology

authors： Serefhanoglu S,Aydogdu I,Kekilli E,Ilhan A,Kuku I

更新日期：2008-05-01 00:00:00

abstract：:We have performed a retrospective analysis of all patients with extragastric mucosa-associated lymphoid tissue (MALT) lymphoma treated at our institution to compare the efficacy of first-line therapeutic modalities including surgery, radiation, systemic therapy, and antibiotics. One hundred eighty-five patients with e...

journal_title：Annals of hematology

authors： Wöhrer S,Kiesewetter B,Fischbach J,Müllauer L,Troch M,Lukas J,Mayerhoefer ME,Raderer M

更新日期：2014-08-01 00:00:00

abstract：:The clinical impact of KIT mutations in core binding factor acute myeloid leukemia (CBF-AML) is still unclear. In the present study, we analyzed the prognostic significance of each KIT mutation (D816, N822K, and other mutations) in Japanese patients with CBF-AML. We retrospectively analyzed 136 cases of CBF-AML that h...

journal_title：Annals of hematology

authors： Yui S,Kurosawa S,Yamaguchi H,Kanamori H,Ueki T,Uoshima N,Mizuno I,Shono K,Usuki K,Chiba S,Nakamura Y,Yanada M,Kanda J,Tajika K,Gomi S,Fukunaga K,Wakita S,Ryotokuji T,Fukuda T,Inokuchi K

更新日期：2017-10-01 00:00:00

abstract：:Despite recent advances made in its treatment, multiple myeloma (MM) remains an incurable B cell malignancy. Thus, the objective for treating these patients is to prolong overall survival (OS) and preserve patients' quality of life. We have analyzed data from 264 consecutive MM patients who had their initial visit bet...

journal_title：Annals of hematology

authors： Berenson A,Vardanyan S,David M,Wang J,Harutyunyan NM,Gottlieb J,Halleluyan R,Spektor TM,Udd KA,Eshaghian S,Nassir Y,Eades B,Swift R,Berenson JR

更新日期：2017-03-01 00:00:00

abstract：:Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is an uncommon type of cutaneous lymphoma with an aggressive natural history. It generally carries a poor prognosis despite standard anthracycline-based chemotherapy. The optimum therapy is unknown. We report the case of a 66-year-old man with CD4/CD8 double negat...

journal_title：Annals of hematology

authors： Go RS,Gazelka H,Hogan JD,Wester SM

更新日期：2003-04-01 00:00:00

abstract：:This retrospective study evaluated the benefit of alemtuzumab monotherapy in unselected patients with advanced B-cell chronic lymphocytic leukemia (CLL) and prolymphocytic leukemia (B-PLL) to definitely describe the impact of this antibody in clinical routine use. Data were collected from 208 consecutive, mainly pretr...

journal_title：Annals of hematology

authors： Fiegl M,Stauder R,Steurer M,Mian M,Hopfinger G,Brychtova Y,Skrabs C,Zabernigg A,Schmid F,Haslbaur F,Winder G,Walder A,Lang A,Voskova D,Greil R,Mayer J,Gastl G,Austrian Collaborative Study Group on Alemtuzumab in Chronic

更新日期：2014-02-01 00:00:00

abstract：:A case of an 82-year-old man who suffered an acute ST-elevation myocardial infarction while receiving treatment with intravenous immunoglobulin (IVIg) for thrombocytopenia is discussed. A total of 29 other cases of thromboembolism related to IVIg therapy have been reported, and the incidence seems to be especially hig...

journal_title：Annals of hematology

authors： Hefer D,Jaloudi M

更新日期：2004-10-01 00:00:00

abstract：:The relationship between Epstein-Barr virus (EBV) and the host is profoundly disturbed by allogeneic bone marrow transplantation (BMT) because EBV resides in the recipient's hematopoietic system, which has to be destroyed in the majority of cases, and in the donor's hematopoietic system, i.e., the marrow graft. We hav...

journal_title：Annals of hematology

authors： Gratama JW,Oosterveer MA,Lepoutre J,Fibbe WE,Ringdén O,Vossen JM,Willemze R,Bolhuis RL,van Rood JJ,Ernberg I

更新日期：1992-06-01 00:00:00

abstract：:Venous thromboembolism (VTE), including deep venous thrombosis (DVT) and pulmonary embolism (PE), occurs secondary to a number of hereditary and acquired disorders of hemostasis. A recently recognized polymorphism in Factor V (FV) gene H1299R (also named HR2) has been reported to be a possible risk factor for the deve...

journal_title：Annals of hematology

authors： Otrock ZK,Taher AT,Shamseddeen WA,Zaatari G,Bazarbachi A,Mahfouz RA

更新日期：2008-12-01 00:00:00

abstract：:Previous studies exploring associations between statin use and risk of multiple myeloma (MM) showed inconsistent results. We searched for articles published in English in databases (PubMed, Web of Science, EMBASE, Medline, and Google Scholar) before October 2019. The multivariate odds ratio (OR)/relative risk (RR) and...

journal_title：Annals of hematology

authors： Zhang P,Liu B

更新日期：2020-08-01 00:00:00

abstract：:The matricellular protein SPARC (secreted protein acidic and rich in cysteine)/osteonectin was determined in patients with multiple myeloma and related disease to assess the hypothesized role of SPARC as a possible marker of tumor burden and disease progression. Soluble SPARC was measured by competitive enzyme-linked ...

journal_title：Annals of hematology

authors： Turk N,Kusec R,Jaksic B,Turk Z

更新日期：2005-05-01 00:00:00

abstract：:Single-agent bortezomib, a potent, selective, and reversible inhibitor of the 26S proteasome, has demonstrated clinical efficacy in relapsed and refractory mantle cell lymphoma (MCL). Objective response is achieved in up to 45% of the MCL patients; however, complete remission rates are low and duration of response pro...

journal_title：Annals of hematology

authors： Hutter G,Rieken M,Pastore A,Weigert O,Zimmermann Y,Weinkauf M,Hiddemann W,Dreyling M

更新日期：2012-06-01 00:00:00

abstract：:Lymphoma-associated hemophagocytic lymphohistiocytosis (HLH) is a rare but fatal disease. Differences between B cell and T cell lymphoma-associated HLH remain unclear, specifically clinical characteristics and survival. We retrospectively analyzed 30 lymphoma-associated HLH patients from July 2004 to October 2012. Pat...

journal_title：Annals of hematology

authors： Yu JT,Wang CY,Yang Y,Wang RC,Chang KH,Hwang WL,Teng CL

更新日期：2013-11-01 00:00:00

abstract：:The incidence of multiple myeloma (MM) has increased in the last 20 years, particularly in middle and low-middle income countries. Access to diagnostic and prognostic tests and the availability of effective care is highly variable globally. Latin America represents 10% of the world population, distributed in countries...

journal_title：Annals of hematology

authors： Riva E,Schütz N,Peña C,Ruiz-Argüelles G,Hopkins CR,Bove V,Villano F,Andino L,Suárez L,Martínez H,Navarro J,López-Vidal H,Da Costa O,Pineda MR,Rubio Y,Ramirez J,Choque J,Fantl D

更新日期：2020-05-01 00:00:00

abstract：:To gain insight into the natural history of cytomegalovirus (CMV) infection following unrelated cord blood transplantation (UCBT) in seropositive patients, we analyzed the data of 349 seropositive patients who received UCBT in Korea between 2000 and 2011. CMV reactivation occurred in 49 % (171/349) of the CMV-seroposi...

journal_title：Annals of hematology

authors： Park M,Lee YH,Lee SH,Yoo KH,Sung KW,Koo HH,Lee JW,Kang HJ,Park KD,Shin HY,Ahn HS,Lee JW,Chung NG,Cho B,Kim HK,Koh KN,Im HJ,Seo JJ,Baek HJ,Kook H,Hwang TJ,Lee JM,Hah JO,Lim YJ,Park JE,Lyu CJ,Lim YT,Ch

更新日期：2015-03-01 00:00:00

abstract：:Sickle cell anaemia (SCA; HbSS) is characterised by its clinical variability, which is only partly explained by known genetic factors. Environmental factors are known to contribute to acute problems but their importance in chronic complications has not been analysed. We have studied 93 children with SCA in a single in...

journal_title：Annals of hematology

authors： Mittal H,Roberts L,Fuller GW,O'Driscoll S,Dick MC,Height SE,Thein SL,Rees DC

更新日期：2009-06-01 00:00:00

abstract：:Expression of long non-coding RNA KIAA0125 has been incorporated in various gene expression signatures for prognostic prediction in acute myeloid leukemia (AML) patients, yet its functions and clinical significance remain unclear. This study aimed to investigate the clinical and biological characteristics of AML beari...

journal_title：Annals of hematology

authors： Wang YH,Lin CC,Hsu CL,Hung SY,Yao CY,Lee SH,Tsai CH,Hou HA,Chou WC,Tien HF

更新日期：2021-02-01 00:00:00