Poststenotic dilatation: arterial wall mechanics in response to vibration.

abstract：:Myometrial tissues from guinea pigs were quantitatively examined for gap junctions in electron micrographs. Small numbers of gap junctions were present between smooth muscle cells in myometria of pregnant guinea pigs at days 50 and 65 of gestation. The junctions increased in number and size at parturition on day 69 an...

journal_title：Canadian journal of physiology and pharmacology

authors： Garfield RE,Daniel EE,Dukes M,Fitzgerald JD

更新日期：1982-03-01 00:00:00

abstract：:Depletion of divalent cations before fractionation of the longitudinal muscle of the guinea pig ileum yielded a sarcolemma-enriched microsomal fraction free of mitochondria. A major portion of the ATPase activity in the presence of Mg, Na, and K was due to stimulation by Na alone. A further small stimulation by K was ...

journal_title：Canadian journal of physiology and pharmacology

authors： James MR,Roufogalis BD

更新日期：1977-10-01 00:00:00

abstract：:Effects of 6-hydroxydopamine (6-OHDA) on rat brain and blood adrenaline (A), noradrenaline (NA), ammonia (NH3), gamma-aminobutyric acid (GABA), and amino acid metabolism prior to and after high pressure oxygen (OHP) induced convulsions have been studied. 6-OHDA reduces GABA and glutamate (Glu) rior to OHP exposure in ...

journal_title：Canadian journal of physiology and pharmacology

authors： Singh AK,Banister EW

更新日期：1978-04-01 00:00:00

abstract：:In Sprague-Dawley rats, we attempted to develop an experimental model to stimulate the cardiac sympathetic nerve. After transverse thoracotomy under anesthesia, a miniature, bipolar electrode was placed on the right ansa subclavia and it was stimulated electrically. The nerve stimulation at 2, 4, and 8.3 Hz (2 ms in d...

journal_title：Canadian journal of physiology and pharmacology

authors： Masuda Y,Matsuoka H

更新日期：1997-02-01 00:00:00

abstract：:Ethanol was administered to rats by oral intubation 3 h after intraperitoneal administration of calcium carbimide. Increased blood acetaldehyde concentration and the presence of acetaldehyde in brain were found for the calcium carbimide--ethanol interaction. There was no detectable brain acetaldehyde for ethanol admin...

journal_title：Canadian journal of physiology and pharmacology

authors： Hoover DJ,Brien JF

更新日期：1981-01-01 00:00:00

abstract：:The present research was to assess the relationship between ABCB1 (G2677T/A, C3435T) polymorphisms and lipid homeostasis as well as risk of liver injury induced by atorvastatin in in-patients from China. The lipid levels (total cholesterol, high-density lipoprotein, triglycerides) as well as metabolic enzymes of hepar...

journal_title：Canadian journal of physiology and pharmacology

authors： Qu KK,Zhang CN,Dong LX,Wang SS,Zhang ZD,Zhang L

更新日期：2020-01-01 00:00:00

abstract：:Glycogen stores (liver and carcass) have been studied in lean and obese Zucker rats. The animals were submitted to one of three feeding conditions: ad libitum, a 48-h fast, or a 48-h fast and food ad libitum for 24 h, and to two environmental conditions, either thermoneutrality or an acute cold exposure (2 days at 4-7...

journal_title：Canadian journal of physiology and pharmacology

authors： Koubi H,Duchamp C,Géloën A,Fréminet A,Minaire Y

更新日期：1991-06-01 00:00:00

abstract：:Methimazole was previously shown to protect rats, mice, and (or) dogs against cisplatin-, cephaloridine-, 2-bromohydro-quinone-, and S-(1,2-dichlorovinyl)-L-cysteine-induced nephrotoxicity. In this study, methimazole effects on gentamicin (GM) induced nephrotoxicity were examined. Rats given GM (40 mg/kg) twice daily ...

journal_title：Canadian journal of physiology and pharmacology

authors： Elfarra AA,Duescher RJ,Sausen PJ,O'Hara TM,Cooley AJ

更新日期：1994-10-01 00:00:00

abstract：:The utilization of triacylglycerol in slow oxidative, fast oxidative-glycolytic, and fast glycolytic skeletal muscle fiber types was examined in rats subjected to a prolonged exhaustive swim. Significant reductions of intramuscular triacylglycerol occurred following 2 h and 40 min of swimming in all muscles containing...

journal_title：Canadian journal of physiology and pharmacology

authors： Spriet LL,Peters SJ,Heigenhauser GJ,Jones NL

更新日期：1985-06-01 00:00:00

abstract：:The effects of the dopamine type-2 receptor (D-2) antagonist domperidone on pituitary and brain amine concentrations and serum gonadotropin levels in the goldfish were investigated. Domperidone caused a long-lasting, dose-dependent depletion of dopamine in the goldfish pituitary. Pituitary concentrations of 5-hydroxyt...

journal_title：Canadian journal of physiology and pharmacology

authors： Sloley BD,Trudeau VL,Dulka JG,Peter RE

更新日期：1991-06-01 00:00:00

abstract：:Childhood cancer survivors can develop significant cardiac dysfunction in adulthood as a consequence of their cancer treatment. Studies have linked heart failure during pregnancy to childhood doxorubicin (DOX) exposure. We hypothesized that DOX injection would reduce cardiac function peripartum and that DOX-treated da...

journal_title：Canadian journal of physiology and pharmacology

authors： Calvé A,Noiles W,Sebag IA,Chalifour LE

更新日期：2012-11-01 00:00:00

abstract：:Single-channel recordings from central neurons of the helix snail, Cepaea nemoralis, revealed two types of channels that could be activated by stretch (i.e., by the membrane deformation produced when suction is applied to the patch pipette). One, a K+ channel (58 pS in physiological solution), was evident in excised a...

journal_title：Canadian journal of physiology and pharmacology

authors： Bédard E,Morris CE

更新日期：1992-02-01 00:00:00

abstract：:The area postrema (AP) is one of the circumventricular organs of the brain and as such it is highly vascular and lacks the normal blood-brain barrier. Anatomical tracing studies have demonstrated afferent projections to AP originating from the paraventricular nucleus, lateral parabrachial nucleus (l-PBN), nucleus trac...

journal_title：Canadian journal of physiology and pharmacology

authors： Ferguson AV

更新日期：1991-07-01 00:00:00

abstract：:Normal penile erectile function is dependent on arterial adequacy, appropriate venous occlusion, neurohumoral factors, and finally the relaxation of penile cavernous trabecular smooth muscle. The present experiments were designed to test whether compounds related to endothelium-derived relaxing factor have a role in p...

journal_title：Canadian journal of physiology and pharmacology

authors： Heaton JP

更新日期：1989-01-01 00:00:00

abstract：:The ability of dystrophic hamsters to maintain their body temperature despite abnormal muscle and brown adipose tissue, two organs involved in thermoregulation, was evaluated. Dystrophic hamsters (CHF 146) between the ages of 30 and 160 days kept at 21 degrees C had core (rectal) temperatures (TR) that were 0.5-1.5 de...

journal_title：Canadian journal of physiology and pharmacology

authors： Desautels M,Dulos RA,Thornhill JA

更新日期：1985-09-01 00:00:00

abstract：:The isometric potentiation associated with myosin phosphorylation is force dependent. The purpose of this study was to assess the influence of a pre-existing period of isometric force on the concentric force potentiation displayed by mouse muscles with and without the ability to phosphorylate myosin. We tested isometr...

journal_title：Canadian journal of physiology and pharmacology

authors： Gittings W,Aggarwal H,Stull JT,Vandenboom R

更新日期：2015-01-01 00:00:00

abstract：:We previously reported that calpain, the Ca2+-sensitive cysteine protease, gets involved in atherogenesis. This study aimed to investigate the effects of calpain inhibitor I (CAI, 5 mg/kg per day) with or without NG-nitro-l-arginine-methyl ester (l-NAME) (100 mg/kg per day), the inhibitor of nitric oxide synthase (NOS...

journal_title：Canadian journal of physiology and pharmacology

authors： Yu L,Yin M,Yang X,Lu M,Tang F,Wang H

更新日期：2018-01-01 00:00:00

abstract：:The ability of human skeletal muscle to provide anaerobically derived ATP during short-term, intense activity is examined. The paper emphasizes the information obtained from direct measurements of substrates, intermediates, and products of the pathways in muscle that provide anaerobically derived ATP. The capacity of ...

journal_title：Canadian journal of physiology and pharmacology

authors： Spriet LL

更新日期：1992-01-01 00:00:00

abstract：:The mesenteric vascular bed preparation of control and pinealectomized (PX) male Wistar rats was used to examine vascular reactivity to two concentrations each of norepinephrine, serotonin, angiotensin, and potassium. Vasoconstrictor responses to 50- and 100-ng injections of norepinephrine and 0.5- and 1.0-microgram i...

journal_title：Canadian journal of physiology and pharmacology

authors： Cunnane SC,Manku MS,Oka M,Horrobin DF

更新日期：1980-03-01 00:00:00

abstract：:It is commonly thought that central nervous system depressant drugs exert their actions through enhancement of gamma-aminobutyrate (GABA)-mediated mechanisms. Recently, the cellular electrophysiological evidence from this laboratory and others suggests that both sedative hypnotics and general anaesthetics inhibit cent...

journal_title：Canadian journal of physiology and pharmacology

authors： Carlen PL,Gurevich N,Davies MF,Blaxter TJ,O'Beirne M

更新日期：1985-07-01 00:00:00

abstract：:The cannabinoid system has been suspected to play a role in the mechanisms of action of dipyrone and paracetamol. Our purpose was to measure the local endocannabinoid and N-acylethanolamide levels in the brain and spinal cord of rats following dipyrone and paracetamol administration. Nociception was assessed 1, 5, and...

journal_title：Canadian journal of physiology and pharmacology

authors： Topuz RD,Gunduz O,Karadag CH,Dokmeci D,Ulugol A

更新日期：2019-11-01 00:00:00

abstract：:Barbiturate actions on excitatory synaptic responses in CA 1 and dentate regions of hippocampal slices were studied to determine whether different effects occur on anatomically distinct synaptic pathways. Pentobarbital facilitated transmission between stratum radiatum inputs and CA 1 neurons at low concentrations (0.0...

journal_title：Canadian journal of physiology and pharmacology

authors： MacIver MB,Roth SH

更新日期：1987-03-01 00:00:00

abstract：:The adenylate cyclase activity induced by norepinephrine (10(-8)-10(-9) M) was studied in hypothalamic particulate fractions from female rats. The effect of estradiol on this activity was studied in rats that were ovariectomized in diestrus 1, injected with estradiol benzoate (50 micrograms/kg body weight), and killed...

journal_title：Canadian journal of physiology and pharmacology

authors： Zubin P,Defagot C

更新日期：1994-11-01 00:00:00

abstract：:Sarcoplasmic reticulum (SR) calcium handling in diaphragm was compared between mdx mice (7-8 weeks old) and age-matched controls. The total SR Ca2+ load was released from the SR by rapidly cooling muscle bundles from 22 to -1 degree C. The plateau amplitude of the rapid cooling contracture (RCC) was considered as an i...

journal_title：Canadian journal of physiology and pharmacology

authors： Khammari A,Péréon Y,Baudet S,Noireaud J

更新日期：1998-12-01 00:00:00

abstract：:The aim of this study was to explore the possibility of identifying clusters of children's games based on estimated energy expenditures and (or) intensity when performed in a guided active play format. The study also investigated whether the identified active play game clusters were repeatable when the games were perf...

journal_title：Canadian journal of physiology and pharmacology

authors： Belcastro AN,Morrison KS,Hicks E,Matta H

更新日期：2012-09-01 00:00:00

abstract：:The present study focused on the interactive pain regulation of endokinin A/B (EKA/B, the common C-terminal decapeptide in EKA and EKB) or endokinin C/D (EKC/D, the common C-terminal duodecapeptide in EKC and EKD) on chimeric peptide MCRT (YPFPFRTic-NH2, based on YPFP-NH2 and PFRTic-NH2) at the supraspinal level in mi...

journal_title：Canadian journal of physiology and pharmacology

authors： He C,Gong J,Yang L,Zhang H,Dong S,Zhou L

更新日期：2016-09-01 00:00:00

abstract：:Rhus tripartitum D.C., Anacardiaceae, has traditionally been used in Tunisia against many illnesses. The present study investigates, for the first time, the protective effects of the methanol extract of Rhus tripartitum fruit (MERT) against CCl4-induced hepatotoxicity and cisplatin-induced nephrotoxicty in Wistar rats...

journal_title：Canadian journal of physiology and pharmacology

authors： Tlili N,Feriani A,Allagui MS,Saadoui E,Khaldi A,Nasri N

更新日期：2016-08-01 00:00:00

abstract：:Salvianolic acid B (Sal B) exerts strong antioxidant activity and eliminates the free radical effect. However, how it affects the antioxidant pathway is not very clear. The objective of this study was to investigate the underlying mechanism of Sal B in CCl4-induced acute liver injury, especially its effect on the Nrf2...

journal_title：Canadian journal of physiology and pharmacology

authors： Jin YM,Tao XM,Shi YN,Lu Y,Mei JY

更新日期：2020-03-01 00:00:00

abstract：:In anesthetized dogs, 60-min occlusions of either the proximal (n = 14), distal (n = 8) left circumflex (LCX), or left anterior descending (LAD, n = 10) arteries were followed by reperfusion. Coronary sinus and aortic norepinephrine and epinephrine plasma concentrations were measured. The ventricular arrhythmias were ...

journal_title：Canadian journal of physiology and pharmacology

authors： Godin D,Campeau N,Nadeau R,Cardinal R,de Champlain J

更新日期：1985-09-01 00:00:00

abstract：:This study investigated the gastroprotective effects of N-acetylcysteine (NAC) against indomethacin-induced gastric ulcer in rats. Ulceration was induced by a single oral administration of indomethacin (30 mg/kg). 50 male albino rats were allocated into 5 equal groups: control group received normal saline orally, indo...

journal_title：Canadian journal of physiology and pharmacology

authors： Soliman NA,Zineldeen DH,Katary MA,Ali DA

更新日期：2017-04-01 00:00:00