Analysis of EBV latency by EBER in situ hybridization in nasopharyngeal carcinoma Spanish patients.

abstract：:Eighteen patients with advanced melanoma of the limbs underwent a single isolation perfusion with melphalan under normothermic conditions, i.e. tissue temperatures between 37.0 and 38.0 degrees C. There were no major complications. In 7 patients complete remission was achieved and in 8 the remission was partial, i.e. ...

journal_title：Anticancer research

authors： Kroon BB,Van Geel AN,Benckhuijsen C,Wieberdink J

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND/AIM:The significance of microvascular invasion (MVI) of hepatocellular carcinoma (HCC) after radiofrequency ablation (RFA) is unknown. PATIENTS AND METHODS:We studied 149 patients with solitary small-sized HCC (≤3 cm) who underwent hepatectomy, and developed a predictive model of MVI using independent facto...

journal_title：Anticancer research

authors： Imai K,Yamashita YI,Yusa T,Nakao Y,Itoyama R,Nakagawa S,Okabe H,Chikamoto A,Ishiko T,Baba H

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Embryonic stem cell expressed Ras (ERas) oncogene is associated with the tumorigenicity of embryonic stem cells. The aim of this study was to clarify the significance of ERas expression in clinical samples of gastric carcinomas. MATERIALS AND METHODS:Three hundred and few tissues from gastric cancer patient...

journal_title：Anticancer research

authors： Kaizaki R,Yashiro M,Shinto O,Yasuda K,Matsuzaki T,Sawada T,Hirakawa K

更新日期：2009-06-01 00:00:00

abstract：:In a prospective study comprising 447 women with endometrial carcinoma stages I-II, the prognostic significance of clinical and flow cytometric variables was evaluated in univariate and multivariate analyses. The parameters studied included age, uterine cavity depth, clinical stage, histopathologic grade, myometrial i...

journal_title：Anticancer research

authors： Wagenius G,Bergström R,Strang P,Gerdes U,Rogo K,Tribukait B,Stendahl U

更新日期：1992-05-01 00:00:00

abstract：AIM:The aim of this study was to investigate the effects of medium-chain triglycerides (MCTs) on chemically-induced hepatic carcinogenesis (HCC) in mice. MATERIALS AND METHODS:In a first set of experiments, mice were treated with diethylnitrosoamine intraperitoneally at two weeks of age. They were fed chow containing ...

journal_title：Anticancer research

authors： Wakana H,Kono H,Fukushima H,Nakata Y,Akazawa Y,Maruyama S,Hagio K,Fujii H,Ichikawa D

更新日期：2019-12-01 00:00:00

abstract：:Bombesin (BN) is a peptide exhibiting a high affinity for the gastrin-releasing peptide (GRP) receptor, which is overexpressed by a variety of tumors, including breast or prostate cancer. The aim of the present study was the investigation of the complexes formed between a series of BN-like peptides and the nuclides (1...

journal_title：Anticancer research

authors： Gourni E,Paravatou M,Bouziotis P,Zikos C,Fani M,Xanthopoulos S,Archimandritis SC,Livaniou E,Varvarigou AD

更新日期：2006-01-01 00:00:00

abstract：:The role of combination chemotherapy regimens in the management of ovarian cancer patients with tumors resistant to platinum compounds has not yet been defined. This multicenter prospective phase II study evaluated the activity and toxicity of the docetaxel-plus-irinotecan combination in ovarian cancer patients whose ...

journal_title：Anticancer research

authors： Polyzos A,Kosmas C,Toufexi H,Malamos N,Lagadas A,Kosmidis C,Ginopoulos P,Ziras N,Kandilis K,Georgoulias V

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:The presence of cytokeratin (CK)-positive cells in the bone marrow (BM) of breast cancer patients is an independent prognostic marker for long-term survival. While the exact nature of these cells remains under investigation, their persistence after chemotherapy is linked to decreased survival, making them a ...

journal_title：Anticancer research

authors： Becker S,Becker-Pergola G,Fehm T,Wallwiener D,Solomayer EF

更新日期：2005-05-01 00:00:00

abstract：:Elevated levels of hypoxia inducible factor-1 (HIF1) are linked to tumor metastasis, angiogenesis, poor patient prognosis and response to chemotherapy. HIF1α is a master regulator of the hypoxic response, including in cancer cells, through transcriptional activation of several target genes. Previously, we identified c...

journal_title：Anticancer research

authors： Masoud GN,Wang J,Chen J,Miller D,Li W

更新日期：2015-07-01 00:00:00

abstract：:A consecutive series of 128 breast cancer patients detected by breast screening were enrolled in this study to analyze their age-dependent characteristics. They were classified into three groups; 40 years or less (young): 26 patients, 41-55 years (middle-aged): 67 patients and 56 years or over (old): 35 patients. The ...

journal_title：Anticancer research

authors： Takei H,Iino Y,Horiguchi J,Maemura M,Koibuchi Y,Horii Y,Nagaoka H,Matsumoto H,Ishikita T,Yokoe T,Morishita Y

更新日期：1998-07-01 00:00:00

abstract：OBJECTIVE:To analyze the prognostic value of DNA multiploidy in a prospective study on frozen surgical tissue samples from primary colorectal cancer. SUMMARY BACKGROUND DATA:Survival data from eleven prospective studies collectively comprising about thirteen hundred patients showed that aneuploidy correlated with a 5-...

journal_title：Anticancer research

authors： Cosimelli M,D'Agnano I,Tedesco M,D'Angelo C,Botti C,Giannarelli D,Vasselli S,Cavaliere F,Zupi G,Cavaliere R

更新日期：1998-05-01 00:00:00

abstract：:Some non-differentiation-induction benzo[a]phenothiazines and mutagenic benz[c]acridines more potently inhibited the mitogen-induced blast transformation of human-peripheral blood lymphocytes than differentiation-induction and non-mutagenic counterparts and phenothiazines. Differential absorption spectrophotometry rev...

journal_title：Anticancer research

authors： Molnar J,Mandi Y,Petri I,Petofi S,Sakagami H,Kurihara T,Motohashi N

更新日期：1993-03-01 00:00:00

abstract：:We investigated the in vitro effects of heparin on the growth and interaction of SW480 colon adenocarcinoma cells with the extracellular matrix proteins laminin, fibronectin and collagen IV. Cell adhesion assays were performed in wells precoated with the proteins mentioned. Tumor cell migration and invasiveness were a...

journal_title：Anticancer research

authors： Antachopoulos CT,Iliopoulos DC,Gagos S,Agapitos MV,Karayannacos PE,Roboli SK,Skalkeas GD

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Neurofibromatosis type 1 (NF1) is an autosomal dominant hereditary disease with complete penetrance and a very variable phenotype. Recent research has shown that postzygotic NF1 gene mutations occur to a far greater extent than previously thought. The phenotype of affected individuals reflects the time of so...

journal_title：Anticancer research

authors： Friedrich RE,Hagel C,Kohlrusch FK,Schanze I,Wieland I,Zenker M

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND/AIM:It is unknown whether hypoxia regulates aurora kinase A (AURKA), a serine/threonine kinase, in neuroblastoma to stimulate cell growth or migration. We sought to determine whether AURKA mediates hypoxia-induced regulation of neuroblastoma tumorigenicity. MATERIALS AND METHODS:Human neuroblastoma BE(2)-C ...

journal_title：Anticancer research

authors： Romain CV,Paul P,Lee S,Qiao J,Chung DH

更新日期：2014-05-01 00:00:00

abstract：:Rauscher erythroleukemia virus of the mouse was originally isolated from an animal bearing a lymphocytic neoplasm. In order to control extraneous influences on leukemia development, we modulated thymus-dependent and bursa-dependent lymphatic tissues and the granulopoietic and erythropoietic components of hemoreticular...

journal_title：Anticancer research

authors： Henkel B,Krueger GR

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND/AIM:Previous studies have revealed that zinc finger and BTB domain-containing 7A (ZBTB7A), an important proto-oncogene, plays multiple roles in carcinogenesis and is up-regulated in several human malignancies. However, the expression of ZBTB7A in colorectal carcinoma (CRC) has seldom been documented. In this...

journal_title：Anticancer research

authors： Joo JW,Kim HS,Do SI,Sung JY

更新日期：2018-05-01 00:00:00

abstract：:The effect of 4,6-benzylidene-D-glucose (BG) on chemically induced primary hepatocellular carcinomas in rats was tested after daily single injections of 85 mg per kg body weight into the aorta through a canula implanted through the right carotid artery. Treatment started immediately following a biopsy confirming the d...

journal_title：Anticancer research

authors： Pettersen EO,Schwarze PE,Dornish JM,Nesland JM

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Human mesenchymal stem cells (MSCs) are thought to be multipotent cells which primarily reside in the bone marrow. Besides their well-known ability to replicate as undifferentiated cells and to differentiate into diverse lineages of mesenchymal tissues, they were recently suggested to also give rise to haema...

journal_title：Anticancer research

authors： Wöhrer S,Rabitsch W,Shehata M,Kondo R,Esterbauer H,Streubel B,Sillaber C,Raderer M,Jaeger U,Zielinski C,Valent P

更新日期：2007-11-01 00:00:00

abstract：AIM:To retrospectively compare the efficacy of two irinotecan-based chemotherapy regimens combined with bevacizumab in first-line therapy of metastatic colorectal cancer (mCRC). PATIENTS AND METHODS:The data of 558 patients with mCRC treated with first-line bevacizumab plus irinotecan-containing regimen were obtained ...

journal_title：Anticancer research

authors： Kocakova I,Melichar B,Kocak I,Bortlicek Z,Büchler T,Dusek L,Petruzelka L,Kohoutek M,Prausová J,Finek J,Mohelnikova-Duchonova B,Vyzula R

更新日期：2015-06-01 00:00:00

abstract：:We report a case with unexpected toxicity after low-dose docetaxel chemotherapy. The patient had a history of clinically latent HCV-positive hepatic cirrhosis when she presented with inoperable pulmonary adenocarcinoma. She was recruited in a protocol combining standard radiotherapy (RT) with docetaxel (30 mg/m2 week)...

journal_title：Anticancer research

authors： Koukourakis MI,Kapsoritakis A,Maltezos E,Potamiano S,Mouzas I,Kouroumalis H

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND/AIM:Diffusion-weighted imaging (DWI) allows for differentiation of benign from malignant tumors, histological tumor types and their grade. The aim of the study was to evaluate the capabilities of DWI using 3 Tesla Magnetic resonance imaging (3T MRI) in the preoperative assessment of renal tumors. PATIENTS A...

journal_title：Anticancer research

authors： Mirka H,Korcakova E,Kastner J,Hora M,Hes O,Hosek P,Ferda J

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Pomegranate extract (PE) is a standardized whole-fruit extract of pomegranate, a fruit with known anticancer properties. MATERIALS AND METHODS:PANC-1 and AsPC-1 human pancreatic cancer cells were used as in vitro models to test the effects of PE. RESULTS:PE treatment induced cell cycle arrest and inhibited...

journal_title：Anticancer research

authors： Nair V,Dai Z,Khan M,Ciolino HP

更新日期：2011-09-01 00:00:00

abstract：:The effect of doxorubicin and Congo Red on prion protein (PrP) infectivity in experimental scrapie was studied to better understand the effect of these compounds in prion diseases and to establish whether a dose-response correlation exists for Congo Red. This was performed in order to test the effectiveness of compoun...

journal_title：Anticancer research

authors： Corato M,Ogliari P,Ceciliani F,Cova E,Bellotti V,Cereda C,Merlini G,Ceroni M

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Patients with type 2 diabetes mellitus (T2DM) as well as patients with obesity have increased cancer mortality. In a previous paper we suggested that there was a trend for decreased mortality in obese individuals with T2DM. The aim of the new analyses was to investigate the same relationship after increasing...

journal_title：Anticancer research

authors： Landman GW,Van Hateren KJ,Kleefstra N,Bilo HJ

更新日期：2010-02-01 00:00:00

abstract：AIM:To assess outcomes in patients treated with first-line bevacizumab-containing therapy for human epidermal growth factor receptor (HER)2-negative metastatic breast cancer (mBC) at a single centre with a homogenous standard-of-care. PATIENTS AND METHODS:Information on patient and disease characteristics, efficacy, a...

journal_title：Anticancer research

authors： Dieras V,Pop S,Berger F,Dujaric ME,Beuzeboc P,Escalup L,Bidard FC,Cottu PH,LE Tourneau C,Piperno-Neumann S,Laurence V,Robain M,Asselain B,Pierga JY

更新日期：2017-03-01 00:00:00

abstract：:Glioblastomas are the most frequent and most malignant astrocytic gliomas. The epidermal growth factor receptor (EGFR) gene is the most frequently amplified and overexpressed in glioblastomas. The expression of bcl-2 and Bax in EGFR-antisense transfected and un-transfected glioblastoma cell line, U87E and U87V was stu...

journal_title：Anticancer research

authors： Wang ZH,Ding MX,Yuan JP,Jin ML,Hao CF,Chew-Cheng SB,Ng HK,Chew EC

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Tenascin-C (TNC) is an extracellular matrix glycoprotein, usually derived from myofibroblasts in the cancer microenvironment. Recently, however, the significance of tumor-derived TNC in initiation of cancer metastasis was disclosed. We investigated the clinical significance of cancer-derived TNC in colorecta...

journal_title：Anticancer research

authors： Takahashi Y,Sawada G,Kurashige J,Matsumura T,Uchi R,Ueo H,Ishibashi M,Takano Y,Akiyoshi S,Iwaya T,Eguchi H,Sudo T,Sugimachi K,Yamamoto H,Doki Y,Mori M,Mimori K

更新日期：2013-05-01 00:00:00

abstract：:The aim of this study was to evaluate the usefulness of image-guided robotic stereotactic radiosurgery for the local control of unresectable liver metastases from colorectal and non-colorectal cancer. Twenty-seven consecutive patients (median age 62 years, range 47-80 years) with liver metastases considered unsuitable...

journal_title：Anticancer research

authors： Ambrosino G,Polistina F,Costantin G,Francescon P,Guglielmi R,Zanco P,Casamassima F,Febbraro A,Gerunda G,Lumachi F

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND/AIM:Few studies have examined the genetic role of matrix metalloproteinases (MMPs) to early detection or prediction in gastric cancer development. In this study, the contribution of MMP7 promoter (A-181G and C-153T) polymorphic genotypes to gastric cancer risk in Taiwanese was investigated for the first time...

journal_title：Anticancer research

authors： Fu CK,Chien YC,Chuang HY,Wang YC,Hwang JJ,Yang MD,Yu CC,Chen JC,Chang WS,Bau DT,Tsai CW

更新日期：2020-02-01 00:00:00