Leucine zipper domain of HIV-1 gp41 interacted specifically with alpha-catenin.

abstract：:Binding of N-formylated chemotactic peptides to specific cell surface receptors on polymorphonuclear leukocytes initiates a wide range of biological responses including migration of inflammatory cells, superoxide release, lysosomal enzyme secretion, calcium mobilization, and cellular activation. We previously establis...

journal_title：Biochemical and biophysical research communications

authors： Shawar SM,Rich RR,Becker EL

更新日期：1995-06-26 00:00:00

abstract：:Various subclasses of messenger ribonucleoprotein particles were prepared from free cytoplasmic and polysome fractions of rat liver on the basis of the homopolymeric content of the constituent RNA's. Two major proteins were evident in the free cytoplasmic preparations: the poly(A)-binding protein was the major constit...

journal_title：Biochemical and biophysical research communications

authors： Ford G,Nichols JL

更新日期：1984-05-16 00:00:00

abstract：:Reactive oxygen species (ROS) are highly reactive and directly attack surrounding biomolecules to deteriorate cellular and tissue functions. Meanwhile, ROS also serve as signaling mediators to upregulate pro-inflammatory cytokine expression via activation of the nuclear factor kappa B signaling pathway, and the increa...

journal_title：Biochemical and biophysical research communications

authors： Hu D,Li D,Shigeta M,Ochi Y,Okauchi T,Neyama H,Kabayama S,Watanabe Y,Cui Y

更新日期：2021-01-08 00:00:00

abstract：:By radiolabeling using NaIO4/[3H]KBH4, a new sialoglycoprotein with Mr of 19,000 was found in the secretion of rat seminal vesicle. It was shown to interact non-covalently with semen coagulum. It existed in three acidic forms with pI values of 4.1, 3.7 and 2.9 and possessed high contents of sialic acids and acidic ami...

journal_title：Biochemical and biophysical research communications

authors： Limpaseni T,Chulavatnatol M

更新日期：1986-04-29 00:00:00

abstract：:Endothelial argininosuccinate synthetase 1 (ASS1) regulates the provision of l-arginine to nitric oxide synthase 3 (NOS3). Previous studies demonstrated that endothelial ASS1 expression was induced by laminar shear stress (LSS) and that this enzyme plays a role in maintaining anti-inflammatory microenvironments throug...

journal_title：Biochemical and biophysical research communications

authors： Mun GI,Boo YC

更新日期：2012-04-06 00:00:00

abstract：:Androstenedione is reduced to form testosterone by 17-beta-hydroxysteroid dehydrogenase (17 beta HSD) and two different reductive isoforms of the enzyme have been identified (types 1 and 3). In this study, levels of mRNA encoding both reductive isoforms have been measured during fetal and post-natal development in the...

journal_title：Biochemical and biophysical research communications

authors： Sha J,Baker P,O'Shaughnessy PJ

更新日期：1996-05-06 00:00:00

abstract：:MicroRNA (miRNA)-mediated gene silencing has recently emerged as a major mechanism of gene expression regulation during development in a variety of species. Little is known, however, about the presence of components of miRNA machinery in mammalian organogenesis. In this study, we report that members of the Argonaute (...

journal_title：Biochemical and biophysical research communications

authors： Lü J,Qian J,Chen F,Tang X,Li C,Cardoso WV

更新日期：2005-08-26 00:00:00

abstract：:The biological function of hnRNP family proteins is widely diverse and involved in pre-mRNA processing, transcriptional regulation, recombination, and telomere maintenance. In the course of our study on the elucidation of biological functions of minisatellite DNA, we isolated several nuclear proteins that bind to the ...

journal_title：Biochemical and biophysical research communications

authors： Tanaka E,Fukuda H,Nakashima K,Tsuchiya N,Seimiya H,Nakagama H

更新日期：2007-06-29 00:00:00

abstract：:The baculovirus expression system has been used to express large quantities of various proteins, including membrane receptors. Here, we reveal a novel property of this expression system to be that certain membrane proteins can be displayed on the budded virus itself. We introduced the genes encoding sterol regulatory ...

journal_title：Biochemical and biophysical research communications

authors： Urano Y,Yamaguchi M,Fukuda R,Masuda K,Takahashi K,Uchiyama Y,Iwanari H,Jiang SY,Naito M,Kodama T,Hamakubo T

更新日期：2003-08-15 00:00:00

abstract：:The mitochondrial respiratory chain (MRC) supplies the majority of the energy requirements of most eucaryotic cells. A null mutation in the Caenorhabditis elegans nuo-1 gene encoding a subunit of complex I (NADH-ubiquinone oxidoreductase) is lethal, leading to a developmental arrest at the third larval stage. To ident...

journal_title：Biochemical and biophysical research communications

authors： Ndegwa S,Lemire BD

更新日期：2004-07-09 00:00:00

abstract：:A phospholipase A2, which is immuno-crossreactive with the anti-rat pancreatic phospholipase A2 antibody, is present in rat gastric mucosa. The content of the enzyme in the gastric mucosa was comparable to that in the pancreas, but the specific activity in the gastric mucosa homogenate (60.7 +/- 19.5 nmol/min/mg) was ...

journal_title：Biochemical and biophysical research communications

authors： Tojo H,Ono T,Okamoto M

更新日期：1988-03-30 00:00:00

abstract：:The rat hemopexin (Hx) gene was isolated and studies of its transcriptional regulation initiated. For analysis by a transient expression assay, the sequence between -2400 and +21 and sequential 5' truncates were linked to the chloramphenicol acetyltransferase (CAT) gene. HepG2 cells transfected with these CAT construc...

journal_title：Biochemical and biophysical research communications

authors： Nagae Y,Muller-Eberhard U

更新日期：1992-05-29 00:00:00

abstract：:Fibroblast growth factor receptor-1c (FGFR1c)/βKlotho (KLB) complex is a receptor of fibroblast growth factor 21 (FGF21). Pharmacologically, FGF21 shows anti-obesity and anti-diabetic effects upon peripheral administration. Here, we report the development of an artificial peptide agonist to the FGFR1c/KLB heterodimer ...

journal_title：Biochemical and biophysical research communications

authors： Sakamoto K,Kawata Y,Masuda Y,Umemoto T,Ito T,Asami T,Takekawa S,Ohtaki T,Inooka H

更新日期：2016-11-04 00:00:00

abstract：:The effects of thyroid hormone on cholesterol 7 alpha hydroxylase, LDL receptor, HMG-CoA reductase, apo A-I and farnesyl pyrophosphate synthetase hepatic mRNA levels were investigated in hypophysectomized rats. Of these mRNAs cholesterol 7 alpha hydroxylase responded the most rapidly and required the lowest dose of T3...

journal_title：Biochemical and biophysical research communications

authors： Ness GC,Pendleton LC,Li YC,Chiang JY

更新日期：1990-11-15 00:00:00

abstract：:Choroidal neovascularization (CNV) is a type of wet age-related macular degeneration (AMD) which is a major cause of blindness in elder patients. Tumor necrosis factor receptor-associated factor 6 (TRAF6) promotes tumor angiogenesis via upregulating the expression of hypoxia-inducible factor 1α (HIF-1α) and vascular e...

journal_title：Biochemical and biophysical research communications

authors： Ding D,Zhu M,Liu X,Jiang L,Xu J,Chen L,Liang J,Li L,Zhou T,Wang Y,Shi H,Yuan Y,Song E

更新日期：2018-09-18 00:00:00

abstract：AIMS:To investigate dynamic changes in the expression of HCN2, HCN4, as well as KCNE1, and KCNE2 mRNA and protein levels in ventricular cells from acute myocardial infarction (AMI) rat hearts. MAIN METHODS:An AMI model was induced by ligating the left anterior descending coronary artery (LAD) of Sprague-Dawley rats. T...

journal_title：Biochemical and biophysical research communications

authors： Xia S,Wang Y,Zhang Y,Deng SB,Du JL,Wang XC,She Q

更新日期：2010-05-07 00:00:00

abstract：:Apoptosis is a mode of cell death characterized by chromatin condensation and disassembly of the nuclear lamina, processes that are also characteristic of mitosis. The apparent similarity between the two events, together with observations that apoptosis can occur following G2 arrest, has led to the suggestion that apo...

journal_title：Biochemical and biophysical research communications

authors： Norbury C,MacFarlane M,Fearnhead H,Cohen GM

更新日期：1994-08-15 00:00:00

abstract：:Cardiolipin and phosphatidic acid-binding protein (CLPABP) controls the stability of the mRNA harboring an AU-rich element (ARE) in the 3' UTR with the help of the RNA stabilizer, human antigen R (HuR). Although CLPABP is localized on the mitochondrial surface as a large protein-RNA complex, its precise role is not ye...

journal_title：Biochemical and biophysical research communications

authors： Maeda A,Uchida M,Nishikawa S,Nishino T,Konishi H

更新日期：2018-01-01 00:00:00

abstract：:Mutations in protein kinase Cgamma (PKCgamma) cause the neurodegenerative disease spinocerebellar ataxia type 14 (SCA14). In this study, expression of an extensive panel of known SCA14-associated PKCgamma mutations as fusion proteins in cell culture led to the consistent formation of cytoplasmic aggregates in response...

journal_title：Biochemical and biophysical research communications

authors： Doran G,Davies KE,Talbot K

更新日期：2008-08-01 00:00:00

abstract：:Disruption of the androgen receptor (AR) in male mice reduces cortical bone expansion and muscle mass during puberty and results in high bone turnover-related cancellous osteopenia. We hypothesized that voluntary wheel running during growth is able to rescue the effects of AR disruption on bone. To this end, 5-week-ol...

journal_title：Biochemical and biophysical research communications

authors： Ophoff J,Callewaert F,Venken K,De Gendt K,Ohlsson C,Gayan-Ramirez G,Decramer M,Boonen S,Bouillon R,Verhoeven G,Vanderschueren D

更新日期：2009-01-02 00:00:00

abstract：:Peroxisome proliferator-activated receptor gamma (PPAR gamma) belongs to a nuclear receptor super family that functions as a master regulator of adipocyte differentiation. PPAR gamma binds its DNA response element together with a partner, retinoid X receptor (RXR), in fat cells. Five RXR ligands (HX600, HX630, DA022, ...

journal_title：Biochemical and biophysical research communications

authors： Sato M,Yajima Y,Kawashima S,Tanaka K,Kagechika H

更新日期：2001-01-26 00:00:00

abstract：:Transport of alpha-ketoisocaproate (KIC), a ketoacid originating from leucine and proposed to be involved in the buffering of glutamate in neurones, was studied in neuroblastoma NB-2a cells. The accumulated KIC was mostly transaminated to leucine, while free keto-acid was detectable either only after prolonged times o...

journal_title：Biochemical and biophysical research communications

authors： Bachowska-Mac M,Nehlig A,Nałecz MJ,Nałecz KA

更新日期：1997-08-08 00:00:00

abstract：:Antigen-specific regulatory CD4(+) T cells have been described but there are few reports on regulatory CD8(+) T cells. We generated islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP)-specific regulatory CD8(+) T cells from 8.3-NOD transgenic mice. CD8(+) T cells from 8.3-NOD splenocytes were...

journal_title：Biochemical and biophysical research communications

authors： Kishi M,Yasuda H,Abe Y,Sasaki H,Shimizu M,Arai T,Okumachi Y,Moriyama H,Hara K,Yokono K,Nagata M

更新日期：2010-03-26 00:00:00

abstract：:Although N-acetyl-L-aspartate (NAA) has been shown to be important to myelin synthesis and osmotic regulation, the biological rationale for the high levels of NAA found in the brain remains unknown. Here, a human astroglial cell line (STTG) was treated with NAA and stimulated with ionomycin, ionomycin/PMA, or IL-1beta...

journal_title：Biochemical and biophysical research communications

authors： Rael LT,Thomas GW,Bar-Or R,Craun ML,Bar-Or D

更新日期：2004-07-02 00:00:00

abstract：:The majority of studies on possible roles for collagen hydrolysates in human health have focused on their effects on bone and skin. Hydroxyprolyl-glycine (Hyp-Gly) was recently identified as a novel collagen hydrolysate-derived dipeptide in human blood. However, any possible health benefits of Hyp-Gly remain unclear. ...

journal_title：Biochemical and biophysical research communications

authors： Kitakaze T,Sakamoto T,Kitano T,Inoue N,Sugihara F,Harada N,Yamaji R

更新日期：2016-09-23 00:00:00

abstract：:Fractionation of rat uterine cells incubated at 22 degrees C with 0.2 nM [3H]-estradiol-17 beta (E2 beta) was performed to analyze the subcellular distribution of internalized hormone. The postnuclear supernatant of homogenates was resolved in Percoll density gradients into six major fractions defined by enzyme marker...

journal_title：Biochemical and biophysical research communications

authors： Pietras RJ,Szego CM

更新日期：1984-08-30 00:00:00

abstract：:Some of the effects of several oncogenes, integrins, growth factors, and neuropeptides are mediated by tyrosine phosphorylation of the non-receptor tyrosine kinase p125(FAK) and the cytoskeletal protein paxillin. We have demonstrated that different stimuli cause tyrosine phosphorylation of p125(FAK) and paxillin in ra...

journal_title：Biochemical and biophysical research communications

authors： García-Benito M,San Román JI,López MA,García-Marín LJ,Calvo JJ

更新日期：2000-08-11 00:00:00

abstract：:Streptokinase (SK), an extracellular protein of several haemolytic strains of Streptococcus, is utilized as a potent thrombolytic agent for the treatment of various myocardial disorders. Functional properties of SK remain unchanged when the first 13 N-terminal amino acid (aa) residues are removed. At present, role of ...

journal_title：Biochemical and biophysical research communications

authors： Pratap J,Kaur J,RajaMohan G,Singh D,Dikshit KL

更新日期：1996-10-03 00:00:00

abstract：:Brush border membrane vesicles (BBMVs) prepared from midguts of Choristoneura fumiferana larvae were pretreated separately with the three CryIA delta-endotoxins from Bacillus thuringiensis subsp. kurstaki HD-1. Crossed affinity immunoelectrophoresis of the solubilized toxin-BBMV complexes, using antibodies raised agai...

journal_title：Biochemical and biophysical research communications

authors： Pang AS

更新日期：1994-03-30 00:00:00

abstract：:Engineering of secreted protease variants exhibiting altered substrate specificity is a challenging task because effective screening methods for the desired property are not available yet. In this study, we sought to obtain variants of Kex2, a yeast Golgi protease, which exhibit altered P2 specificity. We first random...

journal_title：Biochemical and biophysical research communications

authors： Han HE,Rho SH,Lee YJ,Park WJ

更新日期：2005-12-02 00:00:00