The efficacy of thymosin in the treatment of chronic hepatitis B virus infection: a meta-analysis.

abstract：BACKGROUND:[corrected] A predictable consequence of cholestasis is malabsorption of fat-soluble factors, (vitamins A, D, E, K) and other free radical scavengers, such as carotenoids. It has been suggested that oxygen-derived free radicals may be involved in the pathogenesis of chronic liver damage. AIMS:(i) To evaluat...

journal_title：Alimentary pharmacology & therapeutics

authors： Floreani A,Baragiotta A,Martines D,Naccarato R,D'odorico A

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Drug toxicity is a well-known cause of acute pancreatitis (AP). Although many drugs have been associated with AP, the magnitude of the risk of most of them remains largely unknown. AIM:To determine the pancreatotoxic risk of a wide range of drugs. METHODS:The hospital-based Berlin case-control surveillance...

journal_title：Alimentary pharmacology & therapeutics

authors： Douros A,Bronder E,Andersohn F,Klimpel A,Thomae M,Ockenga J,Kreutz R,Garbe E

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Hepatitis vaccination is recommended in patients with chronic liver disease. AIM:To validate Current Procedural Terminology (CPT) codes and drug codes for hepatitis vaccination in administrative databases and determine vaccination rates in hepatitis C virus (HCV)-infected patients in a single large Veterans...

journal_title：Alimentary pharmacology & therapeutics

authors： Hachem CY,Kramer JR,Kanwal F,El-Serag HB

更新日期：2008-11-01 00:00:00

abstract：:The study investigated the oral absorption of two antifungal agents, fluconazole and itraconazole, under conditions of low intragastric acidity. Twelve healthy male volunteers received each of 4 dosing regimens: 200 mg itraconazole alone, 200 mg itraconazole and famotidine, 100 mg fluconazole alone, and 100 mg flucona...

journal_title：Alimentary pharmacology & therapeutics

authors： Lim SG,Sawyerr AM,Hudson M,Sercombe J,Pounder RE

更新日期：1993-06-01 00:00:00

abstract：:In a double-blind, placebo-controlled study of SK&F 94482 (BMY-25368) (400-mg, post-evening meal, for 7 days in 11 healthy subjects), there was a significant 75% decrease in median integrated 24-h intragastric acidity during dosing with the drug (218 mmol h/L) compared with placebo (883 mmol h/L; P = 0.003). The singl...

journal_title：Alimentary pharmacology & therapeutics

authors： Gavey CJ,Smith JT,Nwokolo CU,Pounder RE

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:There is a need for a simple, therapeutic test that is of diagnostic value and can also provide rapid symptom relief in patients who present with classic, mild symptoms suggestive of gastro-oesophageal reflux disease (GERD), when the diagnosis is based on symptom assessment alone. AIM:To assess the diagnost...

journal_title：Alimentary pharmacology & therapeutics

authors： Bate CM,Riley SA,Chapman RW,Durnin AT,Taylor MD

更新日期：1999-01-01 00:00:00

abstract：:Visceral hypersensitivity is highly prevalent in all functional bowel disorders. Most also demonstrate wider patterns of somatic referral of intestinal pain or discomfort. This hypersensitivity may explain the symptoms as the sensitive gut can be more easily provoked by normal or abnormal motor events in the gut. Visc...

journal_title：Alimentary pharmacology & therapeutics

authors： Mertz H

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Dramatic changes in the prevalence and pattern of gastrointestinal disease has taken place in Asia in recent years. AIM:To compare the prevalence of duodenal (DU) and gastric ulcers (GU), erosive oesophagitis (EO), gastric cancer (GCA) and oesophageal cancer (OCA) and Helicobacter pylori infection over a 10...

journal_title：Alimentary pharmacology & therapeutics

authors： Goh KL,Wong HT,Lim CH,Rosaida MS

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Hepatic disturbances in the context of intestinal failure and parenteral nutrition (PN) are frequently encountered and carry a significant burden of morbidity and sometimes mortality. The term intestinal failure-associated liver disease (IFALD) refers to liver injury due to intestinal failure and associated ...

journal_title：Alimentary pharmacology & therapeutics

authors： Bond A,Huijbers A,Pironi L,Schneider SM,Wanten G,Lal S

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Recent genome-wide association studies based on adult and paediatric populations have implicated >30 genes/loci as susceptibility loci for Crohn's disease (CD). AIMS:To investigate whether reported genes/loci were also associated with CD in Canadian children. DESIGN AND METHODS:A case-control design was im...

journal_title：Alimentary pharmacology & therapeutics

authors： Amre DK,Mack DR,Morgan K,Israel D,Deslandres C,Seidman EG,Lambrette P,Costea I,Krupoves A,Fegury H,Dong J,Grimard G,Levy E

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Several clinical trials evaluating the prophylactic effect of allopurinol on postendoscopic retrograde cholangiopancreatography (ERCP) pancreatitis have been published; however, there is no consensus on whether prophylactic allopurinol can reduce the incidence of post-ERCP pancreatitis. AIM:To compare proph...

journal_title：Alimentary pharmacology & therapeutics

authors： Bai Y,Gao J,Zhang W,Zou D,Li Z

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Approximately 20% of primary sclerosing cholangitis (PSC) patients with concomitant inflammatory bowel disease (IBD) have Crohn's disease (CD). AIM:To compare PSC/CD with other PSC patients. METHODS:Retrospective study of 240 PSC patients diagnosed between 1975 and 2012 (median follow-up 12 years). Activit...

journal_title：Alimentary pharmacology & therapeutics

authors： Fevery J,Van Steenbergen W,Van Pelt J,Laleman W,Hoffman I,Geboes K,Vermeire S,Nevens F

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The sequential organ failure assessment (SOFA) score is an effective triage marker following single time point paracetamol (acetaminophen) overdose, but has not been evaluated following staggered (multiple supratherapeutic doses over >8 h, resulting in cumulative dose of >4 g/day) overdoses. AIM:To evaluate...

journal_title：Alimentary pharmacology & therapeutics

authors： Craig DG,Zafar S,Reid TW,Martin KG,Davidson JS,Hayes PC,Simpson KJ

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:There is a lack of evidence for the efficacy of preventive medications for peptic ulcers (PUs) among long-term users of non-steroidal anti-inflammatory drugs (NSAIDs) in Japan. AIM:To estimate the preventive effect by normal dose, not high-dose histamine-H2 receptor antagonists (H2RA) for NSAID-induced ulce...

journal_title：Alimentary pharmacology & therapeutics

authors： Miyake K,Ueki N,Suzuki K,Shinji Y,Kusunoki M,Hiratsuka T,Nishigaki H,Tatsuguchi A,Futagami S,Wada K,Tsukui T,Nakajima A,Yoshino S,Sakamoto C

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:Dexlansoprazole MR is a Dual Delayed Release formulation of dexlansoprazole, an enantiomer of lansoprazole, designed to extend the duration of acid suppression. AIM:To assess the 12-month safety of dexlansoprazole MR in patients with symptomatic gastro-oesophageal reflux disease (GERD). METHODS:In this ran...

journal_title：Alimentary pharmacology & therapeutics

authors： Dabholkar AH,Han C,Paris MM,Perez MC,Atkinson SN,Peura DA

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Subtotal or total colectomy or proctocolectomy with permanent ileostomy (TC-PI) may be a treatment option for medically refractory colonic Crohn's disease (CD). AIM:To perform a systematic review and meta-analysis to evaluate the rate, risk factors and outcomes of CD recurrence after TC-PI. METHODS:In a sy...

journal_title：Alimentary pharmacology & therapeutics

authors： Fumery M,Dulai PS,Meirick P,Farrell AM,Ramamoorthy S,Sandborn WJ,Singh S

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:The efficacy of interferon-alpha plus ribavirin treatment for patients not responding to interferon monotherapy is not well established. AIM:To assess the efficacy and safety of combination therapy with interferon-alpha 2a/2b plus ribavirin by performing a meta-analysis of randomized clinical trials. METHO...

journal_title：Alimentary pharmacology & therapeutics

authors： San Miguel R,Guillén F,Cabasés JM,Buti M

更新日期：2002-09-01 00:00:00

abstract：:Long-term studies have confirmed unequivocally the clinical efficacy of continuous therapy with H2-receptor antagonists in reducing the incidence of ulcer recurrence. However, studies have also reported varying relapse rates as a result of differences in study design, particularly the frequency of endoscopy and hence ...

journal_title：Alimentary pharmacology & therapeutics

authors： Dammann HG,Walter TA

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Recurrent hepatitis C represents a major challenge for the liver transplant community. Given the potentially significant impact that hepatitis C recurrence has on graft and patient survival, several treatment strategies have been utilized to prevent/slow the progression to hepatitis C-related graft failure. ...

journal_title：Alimentary pharmacology & therapeutics

authors： Arjal RR,Burton JR Jr,Villamil F,Rosen HR

更新日期：2007-07-15 00:00:00

abstract：AIM:To evaluate (i) the diagnostic usefulness of a delayed test in initially negative patients; and (ii) the reliability of the rapid urease test, histology or a combination of the two to diagnose Helicobacter pylori during emergency endoscopy in a large clinical practice series. PATIENTS AND METHODS:Records of patien...

journal_title：Alimentary pharmacology & therapeutics

authors： Güell M,Artigau E,Esteve V,Sánchez-Delgado J,Junquera F,Calvet X

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Different authors have postulated both toxic and protective effects for nitric oxide (NO) in the pathophysiology of active inflammation. AIM:To examine the role of NO, especially that produced by the inducible form of nitric oxide synthase (iNOS), by investigating the effects of NOS inhibitors and NO donors...

journal_title：Alimentary pharmacology & therapeutics

authors： Yoshida Y,Iwai A,Itoh K,Tanaka M,Kato S,Hokari R,Miyahara T,Koyama H,Miura S,Kobayashi M

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:A-gliadin residues 31-49 (peptide A) binds to HLA-DQ2 and is toxic to coeliac small bowel. Analogues of this peptide, which bind to DQ2 molecules but are non-toxic, may be a potential route to inducing tolerance to gliadin in patients with coeliac disease. METHODS:Toxicity was investigated with small bowel ...

journal_title：Alimentary pharmacology & therapeutics

authors： Biagi F,Ellis HJ,Parnell ND,Shidrawi RG,Thomas PD,O'Reilly N,Corazza GR,Ciclitira PJ

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Bismuth compounds prevent gastric injury from the short-term administration of nonsteroidal anti-inflammatory drugs. We studied the mechanisms underlying the gastroprotective actions of bismuth subsalicylate against indomethacin-induced injury in rats. METHODS:An in vivo microscopic technique was used in wh...

journal_title：Alimentary pharmacology & therapeutics

authors： Tanaka S,Guth PH,Carryl OR,Kaunitz JD

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:The diagnosis of covert hepatic encephalopathy (CHE) by means of portosystemic encephalopathy syndrome (PSE) test is costly and therefore infrequently performed. AIM:To determine the ability of critical flicker frequency (CFF) alone or in combination with laboratory findings, as an initial test to pre-selec...

journal_title：Alimentary pharmacology & therapeutics

authors： Greinert R,Ripoll C,Hollenbach M,Zipprich A

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The relationship between Helicobacter pylori infection and non-ulcer dyspepsia is not established. AIM:To determine whether eradication of H. pylori might be of benefit in non-ulcer dyspepsia patients. METHODS:We randomly assigned 129 H. pylori infected patients with severe epigastric pain, without gastro-...

journal_title：Alimentary pharmacology & therapeutics

authors： Bruley Des Varannes S,Fléjou JF,Colin R,Zaïm M,Meunier A,Bidaut-Mazel C

更新日期：2001-08-01 00:00:00

abstract：:Forty patients with gastro-oesophageal reflux disease and oesophagitis, documented by endoscopy (grades I to III by the Savary-Miller classification) were randomized to participate in a comparative double-blind trial to receive cisapride (10 mg q.d.s.) or ranitidine (150 mg b.d.) for an 8-week period. Upper gastrointe...

journal_title：Alimentary pharmacology & therapeutics

authors： Arvanitakis C,Nikopoułos A,Theoharidis A,Giannoulis E,Vagios I,Anthopoulou H,Michailidis D,Tourkantonis A

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Drug development in hepatocellular carcinoma (HCC) is limited by disease heterogeneity, with hepatic reserve being a major source of variation in survival outcomes. The albumin-bilirubin (ALBI) grade is a validated index of liver function in patients with HCC. AIM:To test the accuracy of the ALBI grade in p...

journal_title：Alimentary pharmacology & therapeutics

authors： Pinato DJ,Yen C,Bettinger D,Ramaswami R,Arizumi T,Ward C,Pirisi M,Burlone ME,Thimme R,Kudo M,Sharma R

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Few studies have evaluated interferon and ribavirin therapy in hepatitis C virus-infected patients with persistently normal alanine aminotransferase (ALT) levels. AIM:To determine the efficacy and safety of combination therapy in this population, and to evaluate the impact of treatment on health-related qua...

journal_title：Alimentary pharmacology & therapeutics

authors： Bini EJ,Mehandru S

更新日期：2006-03-15 00:00:00

abstract：BACKGROUND:Budd-Chiari syndrome (BCS) is a rare but fatal disease caused by obstruction in the hepatic venous outflow tract. AIM:To provide an update of the pathophysiology, aetiology, diagnosis, management and follow-up of BCS. METHODS:Analysis of recent literature by using Medline, PubMed and EMBASE databases. RES...

journal_title：Alimentary pharmacology & therapeutics

authors： Khan F,Armstrong MJ,Mehrzad H,Chen F,Neil D,Brown R,Cain O,Tripathi D

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Delta virus (HDV)-related chronic hepatitis is difficult to treat. AIMS:To evaluate the efficacy of lamivudine 100 mg daily on serum HDV-RNA, hepatitis D virus antibodies and alanine aminotransferase levels, liver histology, and on hepatitis B surface antigen seroconversion. METHODS:Thirty-one hepatitis B ...

journal_title：Alimentary pharmacology & therapeutics

authors： Niro GA,Ciancio A,Tillman HL,Lagget M,Olivero A,Perri F,Fontana R,Little N,Campbell F,Smedile A,Manns MP,Andriulli A,Rizzetto M

更新日期：2005-08-01 00:00:00