Cytoprotective effect of bismuth subsalicylate in indomethacin-treated rats is associated with enhanced mucus bismuth concentration.

abstract：BACKGROUND:The presence of antibodies towards infliximab (ATI) is associated with lower infliximab (IFX) trough concentrations and loss of response. IFX treatment intensification is effective for restoring response in most, but not all patients with Crohn's disease (CD). AIM:To compare outcome, pharmacokinetics and im...

journal_title：Alimentary pharmacology & therapeutics

authors： Dreesen E,Van Stappen T,Ballet V,Peeters M,Compernolle G,Tops S,Van Steen K,Van Assche G,Ferrante M,Vermeire S,Gils A

更新日期：2018-02-01 00:00:00

abstract：AIM:To compare endoscopic banding ligation vs. no treatment in cirrhotics with intolerance or contraindications to beta-blockers for prevention of first bleeding in portal hypertension. METHODS:A sample size of 214 was planned with all sizes of varices. However, the trial was stopped due to increased bleeding in 52 pa...

journal_title：Alimentary pharmacology & therapeutics

authors： Triantos C,Vlachogiannakos J,Armonis A,Saveriadis A,Kougioumtzian A,Leandro G,Manolakopoulos S,Tzourmakliotis D,Raptis SA,Burroughs AK,Avgerinos A

更新日期：2005-06-15 00:00:00

abstract：INTRODUCTION:Inflammatory bowel disease (IBD) comprising ulcerative colitis (UC) and Crohn's disease (CD) is multigenic disorder. Tremendous progress has been achieved in unravelling the genetic background of IBD. It has led to the discovery of mutations in NOD2 associated with ileal CD and numerous other genes have be...

journal_title：Alimentary pharmacology & therapeutics

authors： Weersma RK,van Dullemen HM,van der Steege G,Nolte IM,Kleibeuker JH,Dijkstra G

更新日期：2007-12-01 00:00:00

abstract：:More than 15 years after the launch of omeprazole in 1988, proton-pump inhibitors remain central to the management of acid-suppression disorders and are unchallenged with regard to their efficacy and popularity among doctors and patients. They are considered safe despite early concerns about the possibility of an asso...

journal_title：Alimentary pharmacology & therapeutics

authors： Raghunath AS,O'Morain C,McLoughlin RC

更新日期：2005-08-01 00:00:00

abstract：:The Consensus Conference on Hepatorenal Syndrome (HRS) organized by the International Ascites Club in 1994 redefined HRS, introduced new diagnostic criteria that are now widely accepted, and proposed the distinction between two types of HRS: type 1 and type 2. Before the introduction of the new therapeutic options, th...

journal_title：Alimentary pharmacology & therapeutics

authors： Angeli P

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Programmed cell death protein-1-targeted immunotherapy has shown promising results in phase II studies of hepatocellular carcinoma. AIM:To evaluate safety and efficacy of nivolumab and pembrolizumab in an international, multicentre, real-world cohort of patients with advanced hepatocellular carcinoma. METH...

journal_title：Alimentary pharmacology & therapeutics

authors： Scheiner B,Kirstein MM,Hucke F,Finkelmeier F,Schulze K,von Felden J,Koch S,Schwabl P,Hinrichs JB,Waneck F,Waidmann O,Reiberger T,Müller C,Sieghart W,Trauner M,Weinmann A,Wege H,Trojan J,Peck-Radosavljevic M,Vogel A

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:The detrimental effect of smoking on development and progression of Crohn's disease (CD) is generally accepted. AIM:To evaluate the awareness of smoking risks in a Belgian inflammatory bowel disease (IBD) population. METHODS:In the out-patient clinic of a tertiary referral centre, 625 consecutive patients ...

journal_title：Alimentary pharmacology & therapeutics

authors： De Bie C,Ballet V,Hendriks N,Coenen S,Weyts E,Van Assche G,Vermeire S,Ferrante M

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Globally, the incidence rates of inflammatory bowel disease (IBD) are increasing; however, data from high-incidence areas are conflicting. Previous studies in Denmark have assessed incidence rates of Crohn's disease (CD) and ulcerative colitis (UC) using short observation periods. AIM:To investigate trends ...

journal_title：Alimentary pharmacology & therapeutics

authors： Lophaven SN,Lynge E,Burisch J

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Differentiating symptoms of irritable bowel syndrome from those of organic intestinal disease is a common clinical problem. Several neutrophil-derived proteins have been proposed as a marker of inflammatory bowel disease. AIM:To compare the diagnostic value of faecal calprotectin, lactoferrin and polymorpho...

journal_title：Alimentary pharmacology & therapeutics

authors： Schröder O,Naumann M,Shastri Y,Povse N,Stein J

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Eosinophilic oesophagitis (EoE) has evolved from a supposedly rare entity to one whose incidence rates are approaching that of inflammatory bowel disease. The factors responsible for this apparent increase in the incidence remain obscure. AIM:To assess various endoscopist and pathologist factors that might ...

journal_title：Alimentary pharmacology & therapeutics

authors： Syed AA,Andrews CN,Shaffer E,Urbanski SJ,Beck P,Storr M

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Furazolidone-based regimens for the eradication of Helicobacter pylori are low cost and effective. Unfortunately, the usual dose of furazolidone is not tolerable in many patients. Lower doses of furazolidone are expected to cause fewer adverse effects. AIM:To investigate the efficacy of low-dose furazolidon...

journal_title：Alimentary pharmacology & therapeutics

authors： Fakheri H,Merat S,Hosseini V,Malekzadeh R

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:(13)CO(2) is produced on metabolism of (13)C-labelled-pantoprazole ([(13)C]-pantoprazole) by CYP2C19. AIM:To investigate whether the [(13)C]-pantoprazole breath test can predict CYP2C19 status and efficacy of proton pump inhibitors (PPIs) in Japanese. METHODS:We classified 110 healthy volunteers as rapid m...

journal_title：Alimentary pharmacology & therapeutics

authors： Furuta T,Kodaira C,Nishino M,Yamade M,Sugimoto M,Ikuma M,Hishida A,Watanabe H,Umemura K

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Randomized, placebo controlled trials are used to assess the efficacy of therapies for Crohn's disease. The placebo response and remission rates vary among studies. AIM:To analyse how the placebo response and remission rates in Crohn's trials have changed over time in the era of parenteral biologic therapie...

journal_title：Alimentary pharmacology & therapeutics

authors： Gallahan WC,Case D,Bloomfeld RS

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori is one of the most prevalent global pathogens and can lead to gastrointestinal disease including peptic ulcers, gastric marginal zone lymphoma and gastric carcinoma. AIM:To review recent trends in H. pylori antibiotic resistance rates, and to discuss diagnostics and treatment paradigms. ...

journal_title：Alimentary pharmacology & therapeutics

authors： Thung I,Aramin H,Vavinskaya V,Gupta S,Park JY,Crowe SE,Valasek MA

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Despite similar clinical symptoms, collagenous colitis (CC) and lymphocytic colitis (LC) are considered two distinct disease entities. AIM:To compare pathoanatomical findings, clinical presentations, risk factors, course of diseases and response to treatment in CC and LC to establish whether they could be s...

journal_title：Alimentary pharmacology & therapeutics

authors： Rasmussen MA,Munck LK

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Coeliac disease is associated with an increased risk of lymphoma and small bowel malignancy, but most studies have found no increased risk of colorectal cancer. AIM:To compare the prevalence of colorectal adenomas in coeliac disease patients with that in non-coeliac disease controls. METHODS:We identified ...

journal_title：Alimentary pharmacology & therapeutics

authors： Lebwohl B,Stavsky E,Neugut AI,Green PH

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Hepatic disturbances in the context of intestinal failure and parenteral nutrition (PN) are frequently encountered and carry a significant burden of morbidity and sometimes mortality. The term intestinal failure-associated liver disease (IFALD) refers to liver injury due to intestinal failure and associated ...

journal_title：Alimentary pharmacology & therapeutics

authors： Bond A,Huijbers A,Pironi L,Schneider SM,Wanten G,Lal S

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:In patients with chronic hepatitis C virus infection and persistently normal alanine aminotransferase levels, liver fibrosis has been reported in 0-22% of cases and advanced liver disease in 5-10% of cases. AIM:To determine whether patients with persistently normal alanine aminotransferase levels clear infe...

journal_title：Alimentary pharmacology & therapeutics

authors： Mangia A,Spinzi G,Vuturo O,Pazienza V,Iacobellis A,Piattelli M,Giacobbe A,Leandro G,Piermanni V,Minoli G,Montalto G,Andriulli A

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Strong acid inhibition using esomeprazole increases cure rates with triple therapy and 10-day treatments are more effective than 7-day ones. The combination of amoxicillin plus metronidazole at full doses, and using a physiologically-correct schedule three times a day, and has been shown to overcome metronid...

journal_title：Alimentary pharmacology & therapeutics

authors： Sánchez-Delgado J,García-Iglesias P,Castro-Fernández M,Bory F,Barenys M,Bujanda L,Lisozain J,Calvo MM,Torra S,Gisbert JP,Calvet X

更新日期：2012-07-01 00:00:00

abstract：AIM:To determine factors affecting compliance of a follow-up colonoscopy in patients with previously diagnosed adenomatous colon polyps. METHODS:A retrospective review was performed on patients with adenomatous polyps excised between January and December 1998. Twenty-nine clinical factors were assessed in patients gro...

journal_title：Alimentary pharmacology & therapeutics

authors： Siddiqui AA,Patel A,Huerta S

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:The combination of omeprazole and amoxycillin has demonstrated effectiveness with very few side-effects in the treatment of H. pylori infection, however cure rates have varied widely. The present study addresses the question as to the extent to which the cure rate of H. pylori infection depends on the size o...

journal_title：Alimentary pharmacology & therapeutics

authors： Miehlke S,Mannes GA,Lehn N,Hele C,Stolte M,Bayerdörffer E

更新日期：1997-04-01 00:00:00

abstract：:Oral ulceration is a common complaint of patients attending out-patient clinics. The aim of this review is to provide the gastroenterologist with a differential diagnosis of oral ulceration, and a practical guide for the management of recurrent aphthous stomatitis, including topical and systemic therapy. The associati...

journal_title：Alimentary pharmacology & therapeutics

authors： Field EA,Allan RB

更新日期：2003-11-15 00:00:00

abstract：AIM:To develop a scale to assess the severity of hepatic encephalopathy using simple dichotomic items. METHODS:A list of 48 items was created by selecting items that are simple to recognize and categorize; it was applied to thirty-six cirrhotic in-patients with episodic encephalopathy, in addition to the adapted-West-...

journal_title：Alimentary pharmacology & therapeutics

authors： Ortiz M,Córdoba J,Doval E,Jacas C,Pujadas F,Esteban R,Guardia J

更新日期：2007-09-15 00:00:00

abstract：BACKGROUND:Hispanic-Americans are a rapidly growing population in the United States, yet gastro-oesophageal reflux disease (GERD) is not well studied in this population. AIM:To compare the efficacy of esomeprazole, lansoprazole and pantoprazole in suppressing gastric acid, including the area of the 'acid pocket,' in H...

journal_title：Alimentary pharmacology & therapeutics

authors： Morgan D,Pandolfino J,Katz PO,Goldstein JL,Barker PN,Illueca M

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:The effects of proton pump inhibitors and Helicobacter pylori infection on the distribution of drugs used for the eradication of the bacteria are poorly understood. AIM:The aim of this study was to investigate the effects of a 7-day administration of 20 mg of omeprazole on the pharmacokinetics of amoxicilli...

journal_title：Alimentary pharmacology & therapeutics

authors： Ortiz RA,Calafatti SA,Corazzi A,Souza JM,Deguer M,De Souza CA,Marchioretto MA,Bernasconi G,Ferraz JG,Pedrazzoli J Jr

更新日期：2002-06-01 00:00:00

abstract：:Coeliac disease is a chronic inflammatory condition associated with small intestinal injury that results in the malabsorption of different nutrients. The damaging factor is gluten present in wheat, barley and rye. The diagnosis relies on the clinical picture of the patient, serological markers for coeliac disease, cha...

journal_title：Alimentary pharmacology & therapeutics

authors： Abdulkarim AS,Murray JA

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Cirrhotic patients with spontaneous bacterial peritonitis (SBP) have elevated rates of renal impairment and mortality. It has been shown that cefotaxime plus albumin infusion decrease renal impairment compared with antibiotic treatment alone, in patients with serum bilirubin >4 mg/dL or creatinine >1 mg/dL. ...

journal_title：Alimentary pharmacology & therapeutics

authors： Cartier M,Terg R,Lucero R,Muñoz A,Romero G,Levi D,Miguez C,Abecasis R

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Tacrolimus is a calcineurin inhibitor commonly used for prophylaxis of rejection in renal and liver transplantation. There are limited but favourable data regarding its possible use in patients with inflammatory bowel disease (IBD). AIMS:To evaluate the efficacy and safety of tacrolimus in patients with IBD...

journal_title：Alimentary pharmacology & therapeutics

authors： Rodríguez-Lago I,Castro-Poceiro J,Fernández-Clotet A,Mesonero F,López-Sanromán A,López-García A,Márquez L,Clos-Parals A,Cañete F,Vicuña M,Nantes Ó,Merino O,Matallana V,Gordillo J,Elorza A,Vicente R,Casanova MJ,Ferreiro-

更新日期：2020-05-01 00:00:00

abstract：:In a randomly allocated, double-blind, endoscopically controlled study, 98 patients with gastric ulcers were treated with either (a synthetic prostaglandin of E2-like structure) enprostil 70 micrograms b.d. or 150 mg ranitidine b.d. The healing rates at 4, 8 and 12 weeks were enprostil 57, 91 and 94% and for ranitidin...

journal_title：Alimentary pharmacology & therapeutics

authors： Morgan AG,Pacsoo C,Taylor P,McAdam WA

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Comparative long-term efficacy of entecavir (ETV) and tenofovir disoproxil fumarate (TDF) for prevention of disease progression to hepatocellular carcinoma (HCC) among high-risk patients with chronic hepatitis B (CHB)-related compensated cirrhosis is controversial. AIMS:To compare the long-term efficacy of ...

journal_title：Alimentary pharmacology & therapeutics

authors： Hu TH,Yueh-Hsia Chiu S,Tseng PL,Chen CH,Lu SN,Wang JH,Hung CH,Kee KM,Lin MT,Chang KC,Lin MC,Chien RN

更新日期：2020-12-01 00:00:00