Abstract:
BACKGROUND:The prognostic factors of adult granulosa cell tumor (AGCT) have not been well defined. METHODS:In 27 AGCT patients, we examined clinical stage, microscopic patterns, mitotic index (MI), and lymph-vascular space invasion (LVSI) to determine whether these factors were related to disease-free survival (DFS) of patients with AGCT. We also performed immunohistochemical examination for p53. RESULTS:Seventeen cases represented stage I tumors, four stage II, five stage III, and one stage IV. Patients with stage I disease had more favorable prognosis than those with stage II to IV disease (p=0.034). There was no relation between the microscopic patterns and the DFS. The MI, which was categorized into < or =3/10 high power field (HPF) and > or =4/10 HPF, was significantly related to patients DFS (p<0.0005). The DFS time for patients with moderate or prominent LVSI was significantly shorter than that for patients with no or minimal LVSI (p<0.0001). By multivariate analysis, MI and LVSI were shown to be independent prognostic factors. Five of seven patients with recurrent tumor had extrapelvic spread; two in the abdominal cavity and three in the liver. CONCLUSION:The results of this study suggest that prognosis for patients with AGCT depends on the MI and LVSI. During the follow-up period of patients, they need to be examined for distant metastasis including liver.
journal_name
Acta Obstet Gynecol Scandjournal_title
Acta obstetricia et gynecologica Scandinavicaauthors
Fujimoto T,Sakuragi N,Okuyama K,Fujino T,Yamashita K,Yamashiro S,Shimizu M,Fujimoto Sdoi
10.1034/j.1600-0412.2001.801120.xsubject
Has Abstractpub_date
2001-11-01 00:00:00pages
1069-74issue
11eissn
0001-6349issn
1600-0412pii
801120journal_volume
80pub_type
杂志文章abstract:BACKGROUND:In this study of women who had undergone an emergency caesarean section (EmCS), the aim was to examine the associations between, on the one hand, the new mother's sense of coherence (SOC) and obstetric and demographic variables a few days postpartum, and on the other hand, post-traumatic stress symptoms 3 mo...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016340701507693
更新日期:2007-01-01 00:00:00
abstract::From January 1984 to October 1986, a total of 185 prenatal diagnostic procedures were performed, viz. 120 chorionic villus samplings, 42 fetal blood samplings, 12 skin biopsies and 11 tumor biopsies. All procedures were performed under continuous ultrasound guidance. The methods are described, and indications for each...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348709015728
更新日期:1987-01-01 00:00:00
abstract::To differentiate between ovarian carcinoma and benign ovarian tumor, we compared alpha-hydroxybutyrate dehydrogenase (HBD), lactate dehydrogenase (LDH) and its isoenzyme activities in serum in 115 patients with ovarian carcinoma and benign ovarian tumor. Both serum HBD activity and total LDH activity in ovarian cancer...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348509156361
更新日期:1985-01-01 00:00:00
abstract::The effect of single intramuscular injection of 15(S)15 methyl PGF2α . (Prostin 15M, Upjohn) on cervical dilatation was tried in women during first trimester pregnancy. Prostin 15M was given at a dose of 250 µg. Three hours later the cervical dilatation and uterine consistency were assessed and recorded, prior to vacu...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.1988.67.s145.55
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:To determine the significance of an inappropriately mature placenta on ultrasound examination (Grannum classification), in a low-risk obstetric population. Scans were performed at 36 weeks' gestation. The study group comprised patients demonstrating a grade III placenta, and the control group comprised patie...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.0001-6349.2005.00563.x
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:In vitro fertilization (IVF) surrogacy makes it possible for women who do not have a functional uterus to have their own genetic offspring. We describe here our experience of IVF surrogacy in Finland over a 10-year period. METHODS:This retrospective study included 17 women who underwent ovarian stimulation ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,多中心研究
doi:
更新日期:2002-08-01 00:00:00
abstract:BACKGROUND:To investigate the levels of maternal serum secretory acetylcholinesterase from a sample of pregnancies involving fetal neural tube defects and compare those results with alphafetoprotein levels. METHODS:Secretory acetylcholinesterase levels were measured using a new Enzyme Capture Immunoassay, in a small b...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::Association between the histidine-rich glycoprotein (HRG) C633T single nucleotide polymorphism (SNP) and recurrent miscarriage was investigated in a case-control study. The cases constituted 187 women with recurrent miscarriage that were compared with 395 controls who had delivered a child and had no history of miscar...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.12155
更新日期:2013-08-01 00:00:00
abstract::A case of benign Müllerian tumor of the ovary in a 53-year old woman is reported. The stromal element consisted of rhabdomyoblasts which clearly indicate that this tumor belongs to the Müllerian family. She remains free of disease 12 months following an abdominal hysterectomy and bilateral salpingo-oophorectomy. ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349209021101
更新日期:1992-08-01 00:00:00
abstract:BACKGROUND:The aim was to evaluate the psychological and physical impact on women submitting to early amniocentesis or chorionic villus sampling and their preferences concerning fetal invasive procedures in a forthcoming pregnancy. METHOD:Fifty-one women undergoing early amniocentesis or chorionic villus sampling at 1...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2001-06-01 00:00:00
abstract:OBJECTIVE:To provide an epidemiological description of the use of ultrasound in obstetrics in Denmark and to analyse whether screening per se reduces the mean number of obstetric ultrasound examinations for all pregnant women. DESIGN:Questionnaire study based on hospital records and patient interviews. SETTING:All Da...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349209041442
更新日期:1992-10-01 00:00:00
abstract:BACKGROUND:The aim of this study was to examine the extent of wishes for and realised choices of alternative and conventional birth care in Finland based on survey and registry data. METHODS:A population-based national survey to 3000 women of reproductive age and 400 men aged 18-24 and 40-44 in Finland and a cross-sec...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:
更新日期:1998-08-01 00:00:00
abstract::The biological effects of tumor necrosis factor (TNF) are mediated through its interaction with high affinity receptors on target cells. Secretion of soluble cytokine receptors has been suggested as a mechanism of regulating cytokine activity in vivo. In a previous study we detected soluble TNF receptors (TNFRs) in am...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349209021090
更新日期:1992-08-01 00:00:00
abstract:BACKGROUND:During the war in former Yugoslavia people endured great suffering. Although many had sought refuge in other countries, the majority remained within Bosnia-Herzegovina. Special service for women within the war zone was urgently needed. A Women's Therapy Center was established in Zenica, Bosnia-Herzegovina of...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0412.1997.tb07991.x
更新日期:1997-04-01 00:00:00
abstract::Ovarian cancer patients in whom complete tumor removal is impossible with primary debulking surgery (PDS) may benefit from neoadjuvant chemotherapy and interval debulking surgery. However, the task of performing a pre-operative evaluation of the feasibility of PDS is difficult. We aimed to investigate whether the risk...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.12127
更新日期:2013-06-01 00:00:00
abstract::The long-term consequences and complications of tubal sterilization were studied. Six years after surgery, information was obtained from 208 of 216 women. Five had been pregnant. Eight had been bothered by their scars for 2 years or more. The majority reported improved conjugal relations and a positive impact on marri...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348409156708
更新日期:1984-01-01 00:00:00
abstract:INTRODUCTION:Approximately 85% of vaginal deliveries are accompanied by perineal trauma. The objective of this trial was to compare the incidence of perineal trauma after primary delivery of either the anterior or posterior shoulder during vaginal delivery. MATERIAL AND METHODS:This was a randomized single-blinded tri...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.1111/aogs.12914
更新日期:2016-09-01 00:00:00
abstract::The concentrations of FSH, LH, 17-beta-estradiol (E2), estrone (E1) and progesterone (P) were measured in peripheral and ovarian vein sera obtained at preoperative pelvic angiography from 5 postmenopausal women with malignant ovarian tumors. In 5 others the concentrations of E2, P and testosterone (T) were also measur...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348609155172
更新日期:1986-01-01 00:00:00
abstract:INTRODUCTION:Previous studies have shown conflicting results as to whether unsuccessful medically assisted reproduction is a risk factor for depression among women. This study therefore investigated if women with no live birth after assisted reproductive technology (ART) treatment had a higher risk of unipolar depressi...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.12705
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:To study the cytogenetics, ultrasound findings, biochemical screening, perinatal outcome, and associated abnormalities in cases of omphaloceles associated with umbilical cord cysts. METHODS:From 1988 to 1994, three cases of omphaloceles with umbilical cord cysts were identified at Mackay Memorial Hospital. ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349509021207
更新日期:1995-11-01 00:00:00
abstract::We treated five patients with stenosing lichen planus [LP] of the vulvovaginal region with methotrexate supplemented with ultrapotent corticosteroid cream and tacrolimus, in combination with surgical dilatation. All patients experienced long-term symptom relief, and there was only minimal or moderate re-stenosing of t...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016340601110721
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:we examined the influence of the androgen receptor gene (AR) CAG microsatellite (AR-CAG) repeat polymorphism and X-chromosome inactivation (XCI) pattern on ovarian reserve markers (follicle stimulating hormone (FSH) and antral follicle count on menstrual cycle day 3-5) and disease etiology in patients with po...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349.2010.526182
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:The objective of the study was to assess the relationship between maternal smoking habits and biomarkers of tobacco smoke measured in cord serum. METHODS:The study population comprised 202 mothers, 42 daily smokers, 24 occasional smokers and 136 nonsmokers. Information on maternal smoking habits was collect...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349609055025
更新日期:1996-11-01 00:00:00
abstract:BACKGROUND:The rate of cesarean section (CS) is increasing in Sweden as well as in most of the industrialized world. One of the most common indications for emergency CS is protracted labor. To what extent fetal pelvic disproportion is a cause of protracted labor is unclear. The value of pelvimetry has been questioned. ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016340600593521
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Our objective was to investigate the role of hydrogen peroxide in the vasocontraction induced in the human umbilical artery by serotonin. METHODS:Umbilical arteries collected from healthy women at term were cut helically and suspended in an organ bath to record isometric mechanical activity. In Study I, we ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349609054704
更新日期:1996-10-01 00:00:00
abstract::Researchers in Copenhagen, Denmark conducted a study to determine if an IUD in a normal woman retards endometrial development. 14 Lippes loop users and 14 controls were studied. The device users had had their IUDs inserted at least 1 year previously and menstruated regularly. The basal temperature curve determined ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016347309158323
更新日期:1973-01-01 00:00:00
abstract:OBJECTIVE:To compare the neonatal outcome after a trial of labor (TOL) with that after an elective cesarean section (CS) following one previous cesarean delivery, considering the indication for the first CS. DESIGN:Population-based cohort study. SETTING:Sweden. POPULATION:Women with their first two deliveries betwee...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.12202
更新日期:2013-10-01 00:00:00
abstract:INTRODUCTION:visual inspection of the cervix with acetic acid is used to control the burden of cervical cancer in low and middle-income countries. This method has some limitations and HPV DNA testing may be an alternative, but it is expensive and requires a laboratory setup. A cheaper and faster HPV tests have been dev...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.14101
更新日期:2021-01-26 00:00:00
abstract::Congenital granular cell myoblastoma of the newborn is a rare tumor. The combination of polyhydramnios caused by obstruction of the infant's mouth by this tumor is extremely rare, and this is the first published report of such a condition. ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348609157400
更新日期:1986-01-01 00:00:00
abstract:INTRODUCTION:An increased risk of preterm birth in women with joint hypermobility syndrome or Ehlers-Danlos syndrome is suspected. MATERIAL AND METHODS:In this nationwide cohort study from 1997 through 2011, women with either joint hypermobility syndrome or Ehlers-Danlos syndrome or both disorders were identified thro...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.13043
更新日期:2017-01-01 00:00:00