Elevated serum alpha-hydroxybutyrate dehydrogenase in patients with ovarian carcinoma.

Abstract:

:To differentiate between ovarian carcinoma and benign ovarian tumor, we compared alpha-hydroxybutyrate dehydrogenase (HBD), lactate dehydrogenase (LDH) and its isoenzyme activities in serum in 115 patients with ovarian carcinoma and benign ovarian tumor. Both serum HBD activity and total LDH activity in ovarian cancer patients were significantly (p less than 0.001) higher than that in patients with benign ovarian tumor. From analysis of serum LDH isoenzymes, a significant decrease in LDH-1, and significant increases in LDH-4 and LDH-5 in ovarian cancer patients were observed, when compared with those in patients with benign ovarian tumor. When the ovarian cancer mass could be removed surgically, a significant decrease in the HBD was observed, suggesting that the HBD might fairly reflect the tumor burden. Serum HBD activities in a half of ovarian cancer patients were higher than the mean +2 SD of those in benign control subjects.

authors

Kikuchi Y,Momose E,Kizawa I,Kuki E,Kato K

doi

10.3109/00016348509156361

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

553-6

issue

7

eissn

0001-6349

issn

1600-0412

journal_volume

64

pub_type

杂志文章
  • Effects of hormones on uPA, PAI-1 and suPAR from cultured endometrial and ovarian endometriotic stromal cells.

    abstract:PROBLEM:To investigate whether endometriotic stromal cells release the urokinase plasminogen activator, soluble urokinase plasminogen activator receptor and plasminogen activator inhibitor-1. If so, to establish if there are any differences between endometrial stromal cells from women with and without endometriosis, an...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: Guan YM,Carlberg M,Bruse C,Carlström K,Bergqvist A

    更新日期:2002-05-01 00:00:00

  • Trends in the incidence and mortality of ovarian cancer in Denmark 1978-2002. Comparison with other Nordic countries.

    abstract:BACKGROUND:The Nordic countries are well-known high-incidence areas of ovarian cancer, but even within the Nordic countries, differences exist. METHODS:Focus in this descriptive epidemiological study is to assess developments in incidence and mortality of ovarian cancer in Denmark 1978-2002 and to make a comparison wi...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.0001-6349.2005.00878.x

    authors: Kjaerbye-Thygesen A,Huusom LD,Frederiksen K,Kjaer SK

    更新日期:2005-10-01 00:00:00

  • Emergency cesarean delivery in induction of labor: an evaluation of risk factors.

    abstract:BACKGROUND:Induction of labor has been associated with an increased risk of emergency cesarean delivery. Knowledge of factors that influence the risk of cesarean delivery in women with induced labor is limited. METHODS:We performed a case-control study, nested within a population-based cohort of women with induced lab...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.0001-6349.2005.00620.x

    authors: Cnattingius R,Höglund B,Kieler H

    更新日期:2005-05-01 00:00:00

  • Saline infusion sonohysterography in endometrial cancer: assessment of malignant cells dissemination risk.

    abstract:BACKGROUND:To assess the risk of malignant cells dissemination in patients with endometrial cancer undergoing saline infusion sonohysterography (SIS). METHODS:Fourteen consecutive patients (mean age: 58.1 years, range: 41-74 years) diagnosed as having a clinical stage I endometrial carcinoma and scheduled for surgical...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: Alcázar JL,Errasti T,Zornoza A

    更新日期:2000-04-01 00:00:00

  • Isolated single umbilical artery and the risk of adverse perinatal outcome and third stage of labor complications: A population-based study.

    abstract:INTRODUCTION:Isolated single umbilical artery (iSUA) refers to single umbilical artery cords with no other fetal malformations. The association of iSUA to adverse outcome of pregnancy has not been consistently reported, and whether iSUA carries increased risk of third stage of labor complications has not been studied. ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.13747

    authors: Ebbing C,Kessler J,Moster D,Rasmussen S

    更新日期:2020-03-01 00:00:00

  • Transvaginal ultrasound, endometrial cytology sampled by Gynoscann and histology obtained by Uterine Explora Curette compared to the histology of the uterine specimen. A prospective study in pre- and postmenopausal women undergoing elective hysterectomy.

    abstract:BACKGROUND:The purpose of this study was to evaluate the diagnostic value of transvaginal ultrasound measurement of endometrial thickness, cytology obtained by Gynoscann, and histology of the endometrium sampled by Uterine Explora Curette compared with histology of the uterine specimen as the gold standard. METHODS:Co...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349709024349

    authors: Kufahl J,Pedersen I,Sindberg Eriksen P,Helkjaer PE,Larsen LG,Jensen KL,de Nully P,Philipsen T,Wåhlin A

    更新日期:1997-09-01 00:00:00

  • Serum anti-Müllerian hormone in subfertile women.

    abstract:INTRODUCTION:The correlation between ovarian reserve and infertility remains unclear. Albeit poorly predictive of pregnancy success in in vitro fertilization cycles, serum anti-Müllerian hormone (AMH) has been acknowledged as a surrogate measure of ovarian reserve and is commonly evaluated in women seeking pregnancy. D...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.12761

    authors: Somigliana E,Lattuada D,Colciaghi B,Filippi F,La Vecchia I,Tirelli A,Baffero GM,Paffoni A,Persico N,Bolis G,Fedele L

    更新日期:2015-12-01 00:00:00

  • Best criterion for the assessment of efficacy of tocolysis and choice of most suitable betasympathomimetic.

    abstract::Over a period of 10 years, 645 patients were treated with six different betasympathomimetics because of threatening premature labor during the 24-36 weeks of gestation. Some 603 comparable patients were analysed with various parameters to find the most suitable criterion for assessing the efficacy of tocolysis and the...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.3109/00016348509156363

    authors: Gummerus M

    更新日期:1985-01-01 00:00:00

  • Relation of estriol in saliva to serum estriol during normal pregnancy.

    abstract::As saliva is an easily accessible biological material, compared with 24-hour urine and blood, the salivary concentration of estriol was studied from the 30th to the 41st week of gestation in 268 samples from 124 normal pregnancies. At the same time, venous blood samples were drawn and analyzed for total and unconjugat...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348109154137

    authors: Fischer-Rasmussen W,Gabrielsen MV,Wisborg T

    更新日期:1981-01-01 00:00:00

  • Economics of childbirth.

    abstract:BACKGROUND:Increasing birth rates have raised questions for policy makers and hospital management about the economic costs of childbirth. OBJECTIVE:The purpose of this article is to identify and review all existing scientific studies in relation to the economic costs of alternative modes of childbirth delivery and to ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/aogs.12117

    authors: Fahy M,Doyle O,Denny K,McAuliffe FM,Robson M

    更新日期:2013-05-01 00:00:00

  • Morbidity associated with failed vaginal birth after cesarean section.

    abstract::We investigated morbidity and factors associated with failed vaginal birth after cesarean delivery (VBAC). In a retrospective cohort study maternal and neonatal outcomes of women who underwent VBAC in three Nigerian University Teaching Hospitals were reviewed. Univariate, followed by multivariate analyses, were conduc...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,多中心研究

    doi:10.3109/00016349.2010.499448

    authors: Oboro V,Adewunmi A,Ande A,Olagbuji B,Ezeanochie M,Oyeniran A

    更新日期:2010-09-01 00:00:00

  • Do foreign-born women in Sweden have an increased risk of non-normal childbirth?

    abstract:BACKGROUND:In this cross-sectional study, we analyze whether foreign-born women in Sweden had more non-normal childbirths than Swedish-born women during 1996-1998, adjusting for age, parity, level of education, number of antenatal care visits, and complications in pregnancy. METHODS:The study includes 215 497 singleto...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/j.0001-6349.2005.00686.x

    authors: Robertson E,Malmström M,Johansson SE

    更新日期:2005-09-01 00:00:00

  • Oral administration of the prostaglandin enisoprost induces uterine activity and softens the cervix during first trimester pregnancy.

    abstract::48 patients in the first trimester of pregnancy received a single oral dose of placebo or enisoprost (prostaglandin E1 analogue): 10, 25, 50, 100, 200 or 400 micrograms. Uterine activity was recorded for 1 h before and for 4 h after administration of the study drug with a Millar microtransducer. There was a dose-relat...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.3109/00016348909009903

    authors: Pulkkinen MO,Cohen H,Vuento M

    更新日期:1989-01-01 00:00:00

  • The relationship between carbohydrate intake and glucose tolerance in pregnant women.

    abstract:OBJECTIVE:We verified whether a misdiagnosis of gestational diabetes mellitus can result in pregnant women when glucose tolerance has deteriorated after a low-carbohydrate meal, and tried to elucidate the mechanism behind the different outcome of the test. STUDY DESIGN:Twenty-seven pregnant women were given directions...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1046/j.1600-0412.2003.00187.x

    authors: Takizawa M,Kaneko T,Kohno K,Fukada Y,Hoshi K

    更新日期:2003-12-01 00:00:00

  • Maternal hemoglobin concentration is closely related to birth weight in normal pregnancies.

    abstract::Maternal Hb levels during the third trimester were studied in relation to certain maternal and fetal parameters in 877 apparently normal pregnancies. Low Hb levels at term were closely associated with increased frequency of newborns in the heavy weight-for-date group. Conversely, high maternal Hb levels were closely a...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348409155506

    authors: Sagen N,Nilsen ST,Kim HC,Bergsjø P,Koller O

    更新日期:1984-01-01 00:00:00

  • Treatment of ectopic pregnancy by local injection of hypertonic glucose: a randomized trial comparing administration guided by transvaginal ultrasound or laparoscopy.

    abstract:OBJECTIVE:To study local treatment of ectopic pregnancy by injection of hyperosmolar (50%) glucose, guided either by transvaginal ultrasound or by laparoscopy. METHODS:Eighty women were randomized, 39 into the sonography and 41 into the laparoscopy group. Criteria for inclusion were 1) ectopic pregnancy < or = 4 cm se...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00016349509013476

    authors: Gjelland K,Hordnes K,Tjugum J,Augensen K,Bergsjø P

    更新日期:1995-09-01 00:00:00

  • DNA ploidy and proliferative characteristics of human trophoblasts.

    abstract::By using DNA cytofluorometry, DNA ploidy and the distribution pattern of human trophoblasts at different sites were studied throughout pregnancy, and the proliferative activity during cell differentiation of trophoblasts was discussed. In the first and second trimesters, cytofluorometric nuclear DNA analysis demonstra...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349209007940

    authors: Wakuda K,Yoshida Y

    更新日期:1992-01-01 00:00:00

  • Clinical care of diabetic pregnancies in Northern Finland 1967-1987.

    abstract::Diabetic pregnancies are risk pregnancies with increased perinatal mortality and perinatal morbidity. The purpose of this study was to evaluate retrospcctively the outcome of 567 diabetic pregnancies in the area of Oulu University Hospital periodically from 1967 to 1987. ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349409029416

    authors: Anttila M

    更新日期:1994-10-01 00:00:00

  • Preoperative serum SCC, CA125, and CA19-9 levels and lymph node status in squamous cell carcinoma of the uterine cervix.

    abstract:BACKGROUND:We wanted to investigate the clinical usefulness of determining the pretreatment levels of multiple serum tumor markers in predicting lymph node status and the prognosis for patients with cervical carcinoma. METHODS:The preoperative serum levels of squamous cell carcinoma antigen (SCC), cancer antigens CA12...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1034/j.1600-0412.2002.810513.x

    authors: Takeda M,Sakuragi N,Okamoto K,Todo Y,Minobe S,Nomura E,Negishi H,Oikawa M,Yamamoto R,Fujimoto S

    更新日期:2002-05-01 00:00:00

  • Aromatase inhibitors: possible future applications.

    abstract::In premenopausal women ovaries are the major sites of estrogen production, while in postmenopausal women estrogen is produced by aromatization of ovarian and adrenal androgens in extragonadal sites, mostly in adipose tissue. Aromatase is a cytochrome P450 hemoprotein-containing enzyme complex that catalyzes the rate-l...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.1111/j.0001-6349.2004.00562.x

    authors: Karaer O,Oruç S,Koyuncu FM

    更新日期:2004-08-01 00:00:00

  • Difficulties in the antenatal assessment of neonatal alloimmune thrombocytopenia.

    abstract::In this paper we present a patient with an initially questionable history of neonatal alloimmune thrombocytopenia (NAT) due to materno-fetal HPA-1a (PLA1) incompatibility. No circulating antibodies were detectable in untreated maternal serum, but an adsorption/elution technique enabled the demonstration of the platele...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349309058169

    authors: Marzusch K,Fischer J,Dietl J,Wiest E,Völklein K,Schnaidt M

    更新日期:1993-10-01 00:00:00

  • Verrucous carcinoma of the vulval region.

    abstract::Verrucous carcinoma is a variant of epidermoid carcinoma with distinctive clinical and pathological features. The diagnosis is often difficult. To date, 20 verrucous carcinomas involving the vulva have been reported in the literature. Metastases to the inguino-femoral lymph nodes have not been described. The treatment...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348309155788

    authors: Andreasson B,Bock JE,Strøm KV,Visfeldt J

    更新日期:1983-01-01 00:00:00

  • Prenatal diagnosis of autosomal recessive polycystic kidney disease by ultrasonography and magnetic resonance imaging.

    abstract::Autosomal recessive polycystic kidney disease is a relatively rare congenital disease affecting the kidneys and liver. We noticed the kidney abnormality at 22 weeks gestation and observed the patient till the delivery at 36 weeks of gestation. The ultrasonographic features consisted of bilaterally enlarged hyperechoge...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349109007927

    authors: Nishi T,Iwasaki M,Yamoto M,Nakano R

    更新日期:1991-01-01 00:00:00

  • Pregnancy after cardiac surgery in patients with secondary pulmonary hypertension due to a ventricular septal defect.

    abstract::Pulmonary hypertension is defined as pulmonary artery pressure greater than 30/15 mmHg. The etiologies of pulmonary hypertension can be divided into primary and secondary ones. The causes of the latter include long-lasting left-to-right shunts (congenital cardiac defects e.g. ventricular septal defect), pulmonary thro...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016349409072516

    authors: Alahuhta S,Jouppila P

    更新日期:1994-11-01 00:00:00

  • Hemangioma of the umbilical cord.

    abstract::A case of intrauterine fetal death with a hemangioma and pseudocysts in the umbilical cord is presented. The clinical significance of these rare lesions is not entirely clarified, but of the 20 fully documented cases of umbilical cord hemangiomas, including the present case, only nine were found with live and complete...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.3109/00016349409006260

    authors: Søndergaard G

    更新日期:1994-05-01 00:00:00

  • Fertility preservation in women with borderline ovarian tumors - how does it impact disease outcome? A cohort study.

    abstract:INTRODUCTION:Borderline ovarian tumors are typically indolent neoplasms. Since many are diagnosed in younger women, fertility conservation is an important consideration and has been advocated based on retrospective data. The objective of this study was to identify features impacting on recurrence and survival in a seri...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.13203

    authors: Helpman L,Yaniv A,Beiner ME,Aviel-Ronen S,Perri T,Ben-Baruch G,Hogen Ben-David L,Jakobson-Setton A,Korach J

    更新日期:2017-11-01 00:00:00

  • Spontaneous abortion: a prospective cohort study of younger women from the general population in Denmark. Validation, occurrence and risk determinants.

    abstract:OBJECTIVE:To assess the occurrence of spontaneous abortion, comparing two different data sources. To estimate the rate of spontaneous abortion over a 2-year period, and examine potential predictors of the risk for incident spontaneous abortion. METHODS:We used interview data from a population-based prospective cohort ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016340500494887

    authors: Buss L,Tolstrup J,Munk C,Bergholt T,Ottesen B,Grønbaek M,Kjaer SK

    更新日期:2006-01-01 00:00:00

  • Preterm breech delivery. Early and late complications.

    abstract::One hundred and ten singleton breech infants with a birth-weight less than 2 500 g have been delivered at Huddinge University Hospital during the years 1972-78. The cesarean section rate was 30.1 per cent. Vaginal and abdominal deliveries were compared with regard to perinatal mortality and asphyxial morbidity at birt...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016348109154124

    authors: Nisell H,Bistoletti P,Palme C

    更新日期:1981-01-01 00:00:00

  • A prospective study of female genital chronic graft-versus-host disease symptoms, signs, diagnosis and treatment.

    abstract:INTRODUCTION:Female genital chronic graft-versus-host disease (cGvHD) is a complication of allogeneic hematopoietic cell transplantation (alloHCT) for blood malignancies. Unattended inflammation and fibrosis in the vulva and vagina may lead to total vaginal stenosis. The course and treatment of genital cGvHD was observ...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:10.1111/aogs.13366

    authors: Smith Knutsson E,Björk Y,Broman AK,Helström L,Nicklasson M,Brune M,Sundfeldt K

    更新日期:2018-09-01 00:00:00

  • A case-referent study on fetal bacteremia and late fetal death of unknown etiology in Lithuania.

    abstract:BACKGROUND:The objectives were to test the hypothesis that certain strains of microorganisms are present in fetal blood in a significant proportion of parturient women suffering unexplained third trimester fetal death, and to examine the correlation between fetal bacteremia and histologic chorioamnionitis and vasculiti...

    journal_title:Acta obstetricia et gynecologica Scandinavica

    pub_type: 杂志文章

    doi:

    authors: Maleckiene L,Nadisauskiene R,Stankeviciene I,Cizauskas A,Bergstrom S

    更新日期:2000-12-01 00:00:00