Abstract:
:Association between the histidine-rich glycoprotein (HRG) C633T single nucleotide polymorphism (SNP) and recurrent miscarriage was investigated in a case-control study. The cases constituted 187 women with recurrent miscarriage that were compared with 395 controls who had delivered a child and had no history of miscarriage. Blood samples were collected from each woman, genomic DNA was extracted and genotyped for the HRG C633T SNP. In the whole study population, the percentage of miscarriage was the same, regardless of genotype (C/C 31.2%, C/T 32.9% and T/T 32.5%). However, an association between homozygous T/T carriers and recurrent miscarriage was detected in a subgroup of women with primary recurrent miscarriage (odds ratio 2.44, 95% CI 1.01-5.92). Our results indicate an important role for the HRG C633T SNP in the occurrence of recurrent miscarriage.
journal_name
Acta Obstet Gynecol Scandjournal_title
Acta obstetricia et gynecologica Scandinavicaauthors
Lindgren KE,Kårehed K,Karypidis H,Hosseini F,Bremme K,Landgren BM,Skjöldebrand-Sparre L,Stavreus-Evers A,Sundström-Poromaa I,Akerud Hdoi
10.1111/aogs.12155subject
Has Abstractpub_date
2013-08-01 00:00:00pages
974-7issue
8eissn
0001-6349issn
1600-0412journal_volume
92pub_type
杂志文章abstract:OBJECTIVE: To determine the influence of type 1 diabetes mellitus (T1DM) on the first trimester serum markers of fetal aneuploidy; pregnancy-associated plasma protein-A (PAPP-A) and free beta subunit of human chorionic gonadotropin (free β-hCG) and to evaluate the influence of glycemic control on these parameters in th...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0412.2011.01212.x
更新日期:2012-01-01 00:00:00
abstract::Ultrasonography (US) has been compared with urography (IVU) as a preoperative investigation prior to hysterectomy in 62 patients. In 38 patients the urinary tract was deemed normal by both US and IVU. US and IVU coincided in varying degrees of hydronephrosis in 8 patients and disagreed in one. Of 5 double ureters, US ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348909021018
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Treatment of menorrhagia by heat-destruction of the endometrium, intended to be an alternative to hysterectomy, was investigated in an experimental study. METHOD:A specially designed catheter (CavatermTM) with a silicone balloon containing a self-regulating containing heating element is inserted into the ut...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.3109/00016349609033325
更新日期:1996-04-01 00:00:00
abstract:BACKGROUND:Midwives in Sweden are responsible for taking Papanicolaou (Pap) smears as part of the cervical cancer screening program. The aim of this study was to investigate midwives knowledge, experience and management of the cervical cancer screening program, and their apprehension of women's knowledge about Pap-smea...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016340701371272
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To describe uterine involution in the puerperium with three-dimensional ultrasound. DESIGN:Prospective, longitudinal study. SETTING:Fetal medicine unit, department of obstetrics and gynecology, university referral hospital, Uppsala, Sweden. POPULATION:Fifty women with uncomplicated deliveries and puerperiu...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0412.2012.01418.x
更新日期:2012-10-01 00:00:00
abstract::Maternal Hb levels during the third trimester were studied in relation to certain maternal and fetal parameters in 877 apparently normal pregnancies. Low Hb levels at term were closely associated with increased frequency of newborns in the heavy weight-for-date group. Conversely, high maternal Hb levels were closely a...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348409155506
更新日期:1984-01-01 00:00:00
abstract::Eighteen patients, under the age of 60 years, who have been treated with local excision of the vulva, participated in the study in which sexual function and somatopsychic reactions were evaluated by personal interviews. Furthermore both objective and subjective cosmetic results were registered. After this type of oper...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349209007969
更新日期:1992-02-01 00:00:00
abstract:INTRODUCTION:The purpose of this study was to describe the echographic features and perinatal outcomes of fetuses with absence of ductus venosus. MATERIAL AND METHODS:Retrospective review of 10 cases with absence of ductus venosus diagnosed by prenatal ultrasonography between January 2014 and February 2016 at a single...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.13176
更新日期:2017-10-01 00:00:00
abstract::A case of intrauterine fetal death with a hemangioma and pseudocysts in the umbilical cord is presented. The clinical significance of these rare lesions is not entirely clarified, but of the 20 fully documented cases of umbilical cord hemangiomas, including the present case, only nine were found with live and complete...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,评审
doi:10.3109/00016349409006260
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND:The objective of this study was to test the accuracy of transabdominal color Doppler imaging in the prediction of malignancy of adnexal tumors when integrated in combination with CA 125 levels and two-dimensional ultrasound. METHODS:We considered 129 consecutive patients with a suspected adnexal mass at cli...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349509021184
更新日期:1995-10-01 00:00:00
abstract::This study was performed to investigate the efficacy of oral mifepristone and vaginal gemeprost for termination of early pregnancy. Eighty women requesting first trimester abortion and with amenorrhea of less than 56 days were included. Gestational age was confirmed with ultrasonography. Mifepristone was administered ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349309013347
更新日期:1993-01-01 00:00:00
abstract::Researchers in Copenhagen, Denmark conducted a study to determine if an IUD in a normal woman retards endometrial development. 14 Lippes loop users and 14 controls were studied. The device users had had their IUDs inserted at least 1 year previously and menstruated regularly. The basal temperature curve determined ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016347309158323
更新日期:1973-01-01 00:00:00
abstract::Oral prostaglandin in hourly doses of 0.5 mg PGE2 was given to 58 patients with an initial Bishop score of five or less, for two 12-hour periods in order to prime the cervix. After priming, the patients were induced with oral PGE2; 90% of these patients were delivered. In a control group comprising 59 patients induced...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.3109/00016348309156229
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND:To determine the influence of hyaluronan and its receptor CD44 in the angiogenesis and invasiveness of intravenous leiomyomatosis (IVL). METHODS:Paraffin-embedded sections from four IVL cases and 10 uterine leiomyoma cases were immunohistochemically stained for CD34, CD44, basic fibroblast growth factor (bF...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.0001-6349.2005.00707.x
更新日期:2005-04-01 00:00:00
abstract::Sciatic pain in a young woman was not relieved by orthopedic treatment. The gynecologist found a large hard tumor-like mass in the uterosacral ligament extending to the pelvic wall. Cytologic examination of fine needle aspirate indicated an endometriotic lesion. The large tumor-like mass was extirpated by an extraperi...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348709092967
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Few studies have examined smoking prior to pregnancy and the occurrence of spontaneous abortion, as most studies have addressed the risk of spontaneous abortion in relation to smoking during pregnancy. However, results are not entirely consistent. The aim of the present study was to assess the risk of sponta...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016340600589560
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:The treatment of pain from episiotomy or from tearing of perineal tissues during childbirth is often unapplied, although discomfort may be severe. We performed a randomized double-blind controlled trial to compare the effectiveness and side-effects of two analgesics in the management of postpartum perineal p...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.0001-6349.2005.00758.x
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:Elective cervical cerclage has been purported to prevent spontaneous preterm birth. We present a systematic review to determine the effectiveness of cervical cerclage in preventing spontaneous preterm birth before 34 weeks' gestation. METHODS:Searches were conducted in MEDLINE, EMBASE, Cochrane Library, and...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章,评审
doi:10.1034/j.1600-0412.2003.00081.x
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:To determine whether lipid alterations in hirsute women are due to excessive androgen, low estrogen or to a combination of these abnormalities. DESIGN:Cross sectional study. PATIENTS:Forty-five hirsute women between 15 and 39 years of age. MAIN OUTCOME MEASURES:FSH, LH, 17beta-estradiol, PRL, testosterone,...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016349609047098
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND:The objectives of this paper were to assess the prevalence of different viral infections in relation to late abortions, stillbirths, and congenital malformations in sera from Russian pregnant women and recurrent aborters in order to establish basic knowledge for future pregnancy care. METHODS:Patients were ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1034/j.1600-0412.2001.801110.x
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:Maternal serum anti-D is actively transported across the placenta into the fetal blood where it adheres to D-positive erythrocytes. The anti-D coated red cells attach to Fc-receptors on fetal reticuloendothelial cells and are subsequently phagocytosed and hemolysed. It is not known if anti-D is consumed or r...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:
更新日期:1998-05-01 00:00:00
abstract::Elevated serum lipids in normal pregnancy have been confirmed by the present study. In normal pregnancy the relative fatty acid composition of serum lecithin was characteristically high in palmitic acid (15:0). From the present knowledge of lipid metabolism in pregnancy there is no obvious explanation for this finding...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016347509157774
更新日期:1975-01-01 00:00:00
abstract::In a 30-year-old primigravida with uterus didelphys there occurred, during labor, mutual torsion of the inferior lower uterine segments, the cervix of the pregnant right uterus crossing in front of the lower segment of the non-pregnant left uterus. This blocked the birth canal, and the patient had to be delivered by c...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016348209156606
更新日期:1982-01-01 00:00:00
abstract::The aim of this study is to determine the influence of withdrawal of reimbursement on the uptake of the first-trimester combined test. Until January 2007 the combined test was offered to all pregnant women in a designated geographical area as a pilot study before the introduction of the national screening program in t...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.12518
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVES:Obstetric fistulas are severe sequelae of prolonged obstructed labor, a widespread but incompletely documented problem of low-income countries. Here, we characterize women with obstetric fistula, test the hypothesis that primi- and multipara represent different profiles and that fetal size is an important fa...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016341003801698
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVE:To analyze human papillomavirus (HPV) DNA in umbilical cord blood and in placenta, including its cellular localization. DESIGN:Longitudinal prospective study. SETTING:Maternity Unit of Turku University Hospital, and MediCity, University of Turku. SAMPLES:Placental and cord blood samples obtained at deliver...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016340802468308
更新日期:2008-01-01 00:00:00
abstract:INTRODUCTION:A correct diagnosis of preeclampsia and gestational hypertension is important for treatment and epidemiological studies. Changes in diagnostic criteria and underreporting in certain subsets of patients may hamper validity of the diagnoses. MATERIALS AND METHODS:We validated the discharge diagnoses of pree...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/aogs.13006
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:The advantages of non-closure of the visceral and parietal peritoneum at lower segment cesarean section seems to be evident but in the reports published so far, the number of patients studied has been relatively small and the follow-up periods short. It is obviously of value to reconfirm such important obser...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1034/j.1600-0412.1998.770123.x
更新日期:1998-01-01 00:00:00
abstract:OBJECTIVE:To study to what extent the fetal scalp blood lactate concentration during labor correlates with fetal scalp pH and base deficit, and metabolic acidosis at birth, and to suggest lactate cut-off values to serve as indicators for either reassurance or immediate intervention. DESIGN:A retrospective observationa...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0412.2011.01237.x
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:To show that early discontinuation of oxytocin will not increase the mean duration of the active labor phase in a clinically significant way. DESIGN:Controlled non-inferiority study. SETTING:Department of Obstetrics and Gynecology, University of Caen, Clemenceau Hospital, France. POPULATION:A total of 138 ...
journal_title:Acta obstetricia et gynecologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016340802649816
更新日期:2009-01-01 00:00:00