Genetic detection of lymph node micrometastases in patients with gastric carcinoma by multiple-marker reverse transcriptase-polymerase chain reaction assay.

abstract：BACKGROUND:Estimates of the fecal occult blood test (FOBT) (Hemoccult II) sensitivity differed widely between screening trials and led to divergent conclusions on the effects of FOBT screening. We used microsimulation modeling to estimate a preclinical colorectal cancer (CRC) duration and sensitivity for unrehydrated F...

journal_title：Cancer

authors： Lansdorp-Vogelaar I,van Ballegooijen M,Boer R,Zauber A,Habbema JD

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:The bone destruction in myeloma patients is largely responsible for the clinical features of the disease. However, only recently has attention focused on identifying and developing drugs targeted specifically at the osteolysis. Receptor activator of NF-kappaB ligand (RANKL), macrophage inflammatory protein (...

journal_title：Cancer

authors： Oyajobi BO,Mundy GR

更新日期：2003-02-01 00:00:00

abstract：:A humoral microcytotoxicity assay has been used to study the immune response to human malignant astrocytic tumors. Two series are described. When the assay was performed under uniform, ideal conditions, the sera from 36 of 45 patients with these tumors (80%) produced significant cytotoxicity against allogeneic astrocy...

journal_title：Cancer

authors： Wood WC,Kornblith PL,Quindlen EA,Pollock LA

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:During a population-based local cancer registry, a peculiar type of T-cell lymphoma restricted to the gastrointestinal tract was found in patients living in southwestern Japan. METHODS:Five cases of gastrointestinal (GI) tract T-cell lymphoma were analyzed with immunohistologic examination, ultrastructural ...

journal_title：Cancer

authors： Tokunaga O,Watanabe T,Shimamoto Y,Tokudome S

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:The current analysis of outcomes in a large series of adult patients with intracranial ependymal tumors contributes to the characterization of the primary prognostic factors and to the therapeutic management of this rare disease, for which limited information is available in the literature. METHODS:The auth...

journal_title：Cancer

authors： Reni M,Brandes AA,Vavassori V,Cavallo G,Casagrande F,Vastola F,Magli A,Franzin A,Basso U,Villa E

更新日期：2004-03-15 00:00:00

abstract：:Clinicopathologic correlations were made in 50 patients with follicular large cell (FLC) lymphoma to better define the influence of a variety of clinical and pathologic features on survival and the potential for continuous freedom from disease. The 5- and 10-year actuarial survivals for the entire group of patients ar...

journal_title：Cancer

authors： Horning SJ,Weiss LM,Nevitt JB,Warnke RA

更新日期：1987-04-15 00:00:00

abstract：BACKGROUND:Consumers increasingly consult the Internet for breast cancer information. Concerned about accuracy, multiple organizations developed quality criteria for online content. However, the effectiveness of these tools is unknown. The authors determined whether existing quality criteria can identify inaccurate bre...

journal_title：Cancer

authors： Bernstam EV,Walji MF,Sagaram S,Sagaram D,Johnson CW,Meric-Bernstam F

更新日期：2008-03-15 00:00:00

abstract：BACKGROUND:The objective of this study was to determine the potential economic implications resulting from using exemestane (EXE), a new steroidal, irreversible aromatase inactivator, compared with megestrol acetate (MA) in patients with advanced breast carcinoma. METHODS:The model used the clinical results from the m...

journal_title：Cancer

authors： Hillner BE,Radice D

更新日期：2001-02-01 00:00:00

abstract：:The predisposition of preexisting cirrhotic metabolic liver disease to the development of hepatocellular carcinoma is well established. However, the association between glycogenoses (a form of noncirrhotic metabolic liver disease) and the formation of benign and malignant liver tumors is less well known. The sixth cas...

journal_title：Cancer

authors： Conti JA,Kemeny N

更新日期：1992-03-15 00:00:00

abstract：BACKGROUND:Tumor endothelium represents a valuable target for cancer therapy. The vasculature plays a critical role in the survival and continued growth of solid tumor masses; in addition, the inherent differences between tumor blood vessels and blood vessels associated with normal tissue make the tumor vasculature a u...

journal_title：Cancer

authors： Siemann DW,Chaplin DJ,Horsman MR

更新日期：2004-06-15 00:00:00

abstract：:Twenty-four children aged 3 months to 18 years (median, 12 years) were treated for neurogenic sarcoma at the Children's Hospital of Philadelphia Cancer Research Center from 1958 through 1984. Sixteen patients had neurofibromatosis (NF). The tumors arose in an extremity or in the trunk (15 patients), the retroperitoneu...

journal_title：Cancer

authors： Raney B,Schnaufer L,Ziegler M,Chatten J,Littman P,Jarrett P

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Intracranial meningiomas are common and comprise 20% of all primary brain tumors. Meningiomas infrequently metastasize; however, to the authors' knowledge there are limited data regarding the spread of disease through cerebrospinal fluid (CSF). METHODS:Eight of 200 consecutive patients (4%) with meningiomas...

journal_title：Cancer

authors： Chamberlain MC,Glantz MJ

更新日期：2005-04-01 00:00:00

abstract：:Retinoblastoma should not be considered as the exceptional childhood cancer that shows dominant inheritance, but rather as the typical childhood cancer that embraces a prezygotic and postzygotic subgroup. Postzygotic cases are conceived as involving mutation as a first step too, but with the mutation in somatic rather...

journal_title：Cancer

authors： Knudson AG Jr

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:Racial disparity in the incidence of multiple myeloma is well established; however, to the authors' knowledge, little is known regarding the impact of racial differences on disease characteristics, response to therapy, and clinical outcome. METHODS:The authors studied 453 patients (174 of whom were black an...

journal_title：Cancer

authors： Bhatnagar V,Wu Y,Goloubeva OG,Ruehle KT,Milliron TE,Harris CG,Rapoport AP,Yanovich S,Sausville EA,Baer MR,Badros AZ

更新日期：2015-04-01 00:00:00

abstract：:Fourteen patients with advanced salivary gland malignancies were treated with combination chemotherapy. Five of 13 patients responded to cyclophosphamide and adriamycin and two patients in the responding groups underwent further potentially curable treatment, rendering them disease-free. Three patients with mucoepider...

journal_title：Cancer

authors： Posner MR,Ervin TJ,Weichselbaum RR,Fabian RL,Miller D

更新日期：1982-12-01 00:00:00

abstract：:The authors have shown previously that bone marrow transplant (BMT) patients who self-administered bolus doses of morphine gained equal oral mucositis pain relief while using less drug compared with similar patients receiving morphine by staff-controlled continuous infusion. In a follow-up study they compared the effi...

journal_title：Cancer

authors： Hill HF,Mackie AM,Coda BA,Iverson K,Chapman CR

更新日期：1991-02-15 00:00:00

abstract：BACKGROUND:Elderly people constitute a heterogeneous group and are at an increased risk for the development of cancer. It is not clear whether comorbid conditions and functional status influence clinical decisions and the pattern of referral in elderly cancer patients. The current study investigated functional status m...

journal_title：Cancer

authors： Repetto L,Venturino A,Vercelli M,Gianni W,Biancardi V,Casella C,Granetto C,Parodi S,Rosso R,Marigliano V

更新日期：1998-02-15 00:00:00

abstract：BACKGROUND:Thyroid carcinomas historically have been divided into two groups according to their presumedly separate embryonic origins: those of neuroectodermal derivation (parafollicular or medullary carcinoma [MCT]) and those of foregut endodermal origin (follicular and papillary carcinomas). The validity of this conc...

journal_title：Cancer

authors： Kovacs CS,Masé RM,Kovacs K,Nguyen GK,Chik CL

更新日期：1994-08-01 00:00:00

abstract：:Peripheral blood changes preceding therapy-related leukemia were studied in 105 patients who had received cytotoxic therapy, 53 for Hodgkin's disease and 52 for other cancers. Preleukemic anomalies were observed in 74.3% of the cases, appearing after a mean interval of 68.7 months after diagnosis of the initial cancer...

journal_title：Cancer

authors： De Gramont A,Louvet C,Krulik M,Smadja N,Donadio D,Laporte JP,Brissaud P,Smith M,Delâge JM,Drolet Y

更新日期：1986-08-01 00:00:00

abstract：:The case of a man who developed a leiomyosarcoma in association with a surgically created arteriovenous fistula is reported. This unusual complication of a dialysis fistula is the first reported case of a leiomyosarcoma occurring in a surgically created fistula. ...

journal_title：Cancer

authors： Weinreb W,Steinfeld A,Rodil J,Esparza A,Trebbin W

更新日期：1983-07-15 00:00:00

abstract：:A number of problems inherent to quality of care evaluation have been described above. Although issues such as limited resources and clinical staff resistance may not be specific to cancer care, they certainly impact on the evaluation of the quality of care offered to cancer patients. Other issues such as complexity o...

journal_title：Cancer

authors： Miransky LJ

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Whether fatherhood status affects prostate cancer risk remains controversial. Recently, it was proposed that childless men are at lower prostate cancer risk than men with children and that men with sons may be at lower risk than men with daughters only. METHODS:National population-based register data were u...

journal_title：Cancer

authors： Jørgensen KT,Pedersen BV,Johansen C,Frisch M

更新日期：2008-02-15 00:00:00

abstract：BACKGROUND:The primary objective of this study was to clarify the significance of p21WAF1/CIP1(p21) gene expression in the tumorgenicity of hepatitis B virus (HBV) and hepatitis C virus (HCV) infected human hepatocelluar carcinoma (HCC). METHODS:The authors performed Northern blot hybridization to compare the p21 mess...

journal_title：Cancer

authors： Kobayashi S,Matsushita K,Saigo K,Urashima T,Asano T,Hayashi H,Ochiai T

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Expression of neuroectodermal markers is a key feature of small cell lung carcinoma (SCLC). Although immune responses against a number of these proteins have been associated with paraneoplastic neuronal disease (PND), most patients with SCLC have anti-neuroectodermal antibodies in the absence of PND. Whether...

journal_title：Cancer

authors： Vural B,Chen LC,Saip P,Chen YT,Ustuner Z,Gonen M,Simpson AJ,Old LJ,Ozbek U,Gure AO

更新日期：2005-06-15 00:00:00

abstract：:Some of the issues being addressed in mammography quality assurance are 1) that image quality is the most important technical aspect of mammography; 2) that image quality has improved steadily over the past two decades and will continue to improve at most mammography sites in the United States; 3) that the American Co...

journal_title：Cancer

authors： Hendrick RE

更新日期：1993-08-15 00:00:00

abstract：:The woman treated for gynecologic cancer must contend with a challenging group of issues in her efforts to recover psychologically in the months and years after treatment: chance of dying, changed self-perception, treatment-related menopause, impaired or lost fertility, sexual dysfunction, and relationship problems mu...

journal_title：Cancer

authors： Auchincloss SS

更新日期：1995-11-15 00:00:00

abstract：:This study compared the resting energy expenditure (REE) modifications observed during successive intensive identical chemotherapy courses in non-Hodgkin's lymphoma patients to assess indirectly the metabolic changes induced by the cytotoxic effect of drugs on the tumor. With this therapeutic regimen, reduction of tum...

journal_title：Cancer

authors： Delarue J,Lerebours E,Tilly H,Rimbert A,Hochain P,Guedon C,Piguet H,Colin R

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Strong correlations have been reported between expression of urokinase-type plasminogen activator (uPA) and poor prognosis in several human carcinomas. The clinical significance of secreted levels of uPA, its receptor (uPAR), and its inhibitors (PAI-1 and PAI-2) in the ascites of patients with epithelial ova...

journal_title：Cancer

authors： Chambers SK,Gertz RE Jr,Ivins CM,Kacinski BM

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:Transplantation of donor-derived malignancies during organ transplantation fortunately is very rare. Discontinuation of immunosuppressive medications under these circumstances has previously resulted in complete tumor rejection. Ectopic adrenocorticotropic hormone (ACTH) production may result in Cushing synd...

journal_title：Cancer

authors： Bodvarsson S,Burlingham W,Kusaka S,Hafez GR,Becker BN,Pintar T,Sollinger HW,Albertini MR

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:The presence of tumor cells in peritoneal washing cytology specimens taken during surgery affects the staging of many gynecologic malignancies. Peritoneal washings are often collected routinely, even in cases of presumed benign disease. This study was designed to address whether evaluation of these specimens...

journal_title：Cancer

authors： Sharifi S,Ducatman BS,Wang HH,Fraser JL

更新日期：1999-10-25 00:00:00