Human herpesviruses HHV-4 (EBV) and HHV-6 in Hodgkin's and Kikuchi's diseases and their relation to proliferation and apoptosis.

abstract：BACKGROUND/AIM:Anthracyclines have been proven able to reduce the activity of vinca alkaloids by induction of cell-cycle arrest. The present study aims at identifying the critical initiation steps of signal transduction which transduce the inhibitory effects on the cytotoxicity of vinca alkaloids. MATERIALS AND METHOD...

journal_title：Anticancer research

authors： Ehrhardt H,Pfeiffer S,Schrembs D,Wachter F,Grunert M,Jeremias I

更新日期：2013-12-01 00:00:00

abstract：UNLABELLED:The present study evaluated the frequency of the polymorphism of Interleukin-6 (IL6) in women positive for E6/E7 Human Papillomavirus (HPV) (n=152) and women negative for HPV (n=238), 390 women in total. Material for analysis was obtained at the Federal University of São Paulo. Interleukin-6 polymorphism was...

journal_title：Anticancer research

authors： Porto CR,De Oliveira Kleine JP,Longatto Filho A,Da Silva ID

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:The safety and efficacy of second-line chemotherapy for treating patients with small cell lung cancer (SCLC) and interstitial lung disease (ILD) have not been elucidated to date. PATIENTS AND METHODS:Between January 2005 and September 2013, we analyzed 23 patients with SCLC and ILD who received second-line ...

journal_title：Anticancer research

authors： Fujimoto D,Shimizu R,Kato R,Sato Y,Kogo M,Ito J,Teraoka S,Otoshi T,Nagata K,Nakagawa A,Otsuka K,Katakami N,Tomii K

更新日期：2015-11-01 00:00:00

abstract：AIM:The aim of the present study was to evaluate the correlation between WT1 expression levels and clinical features, to investigate the prognostic value of WT1 expression and to use lentiviral constructs to examine whether overexpression of WT1 affects cell proliferation and invasion in ovarian cancer patients. MATER...

journal_title：Anticancer research

authors： Liu Z,Yamanouchi K,Ohtao T,Matsumura S,Seino M,Shridhar V,Takahashi T,Takahashi K,Kurachi H

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:The recent prevalence of ultrasonography and fine-needle aspiration biopsy (FNAB) has facilitated the detection and diagnosis of papillary thyroid carcinoma. However, there are still cases that are preoperatively misdiagnosed and treated as benign nodules because ultrasonographic and FNAB findings do not pro...

journal_title：Anticancer research

authors： Ito Y,Higashiyama T,Takamura Y,Miya A,Kobayashi K,Matsuzuka F,Kuma K,Miyauchi A

更新日期：2007-03-01 00:00:00

abstract：:In addition to fibronectin-derived peptides, several immunologically distinct peptides have been found to co-purify with fibronectin on gelatin-sepharose affinity chromatography of bovine plasma. We have isolated a 25kdal peptide ("25K") which co-purifies with fibronectin and which is mitogenic for cultured fibroblast...

journal_title：Anticancer research

authors： Channon KM,Ayad SR

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Intradermal or oral administration of lipopolysaccharide derived from Pantoea agglomerans (IP-PA1) has shown prophylactic and antitumor effects without serious side-effects. While it is known that tumor necrosis factor (TNF)-alpha produced by activated macrophages plays an important role in the expression me...

journal_title：Anticancer research

authors： Kadowaki T,Yasui Y,Takahashi Y,Kohchi C,Soma G,Inagawa H

更新日期：2009-11-01 00:00:00

abstract：:Recurrent breast cancer (BC) tends to show an aggressive behavior and the number of cases of long-term survival is limited. Two rare cases of recurrent breast cancer were treated with a multidisciplinary approach. The outcome of the two cases indicated an excellent survival period of more than 13 years after recurrenc...

journal_title：Anticancer research

authors： Uramoto H,Hanagiri T

更新日期：2011-01-01 00:00:00

abstract：:We report the synthesis of a series of merocyanines and the structure-effect relationship as cytotoxic agents for human adenocarcinoma cells in vitro. The cytotoxicity of these compounds in vitro makes them potential anticancer agents. One of these compounds was found active on human and mouse tumor models. ...

journal_title：Anticancer research

authors： Gruda I,Pagé M,Bolduc F,Laliberté S,Noel C

更新日期：1987-11-01 00:00:00

abstract：:The active vitamin D3, 1alpha,25-dihydroxyvitamin D3 (1,25(OH)2D3), is now well recognized as a potent regulator of cell proliferation and differentiation in addition to possessing a regulatory effect on calcium and phosphorus metabolism. From research on the synthesis of 1,25(OH)2D3 analogs with the goal of separatin...

journal_title：Anticancer research

authors： Kubodera N,Hatakeyama S

更新日期：2009-09-01 00:00:00

abstract：:Variants of the Bomirski family of hamster melanomas whose proliferative rates differ inversely with the genetically determined degree of melanogenesis were probed for two proteins critical in melanogenesis: tyrosinase and catalase-B (gp 75). The parental black tumor Ma contained both proteins in abundance. The amelan...

journal_title：Anticancer research

authors： Slominski A,Costantino R,Howe J,Moellmann G

更新日期：1991-01-01 00:00:00

abstract：:Urine and serum samples from a group of 359 individuals were studied in order to evaluate the usefulness of TPA in patients with urological cancers. Serum was taken from 110 people at 12 noon (S1), 5 pm (S2), and 8 am the following day (S3), while urine samples were collected from 73 individuals over three time interv...

journal_title：Anticancer research

authors： Costello CB,Kumar S

更新日期：1986-07-01 00:00:00

abstract：:Pallents with breast cancer exhibit an increased risk of developing cancer from other organs, a risk that might increase due to tamoxifen treatment. This drug has been found to cause activation of oestrogen receptors, leading to oestrogenic effects on the postmenopausal endometrium. We report follow-up of 94 patients ...

journal_title：Anticancer research

authors： Willén R,Lindahl B,Andolf E,Ingvar C,Liedman R,Ranstam J

更新日期：1998-01-01 00:00:00

abstract：:The identification of new prognostic parameters in Superficial Transitional Cell Carcinoma of the Bladder (STCCB) is important since conventional methods are often insufficient for prognostic purposes. We studied the proliferation activity and the DNA ploidy status of 60 pTa and pT1 Superficial Transitional Cell Carci...

journal_title：Anticancer research

authors： Pantazopoulos D,Ioakim-Liossi A,Karakitsos P,Aroni K,Kakoliris S,Kanavaros P,Kyrkou KA

更新日期：1997-01-01 00:00:00

abstract：AIM:The current study reports the type of salvage chemotherapy following osimertinib and its treatment efficacy in patients with non-small-cell lung carcinoma (NSCLC) who acquire resistance to osimertinib. PATIENTS AND METHODS:In this retrospective cohort study, data from the medical charts of 40 patients with NSCLC t...

journal_title：Anticancer research

authors： Tone M,Inomata M,Awano N,Kuse N,Jo T,Yoshimura H,Minami J,Takada K,Miyamoto S,Izumo T

更新日期：2020-04-01 00:00:00

abstract：:In the present study the effects of the anticancer drug Doxorubicin (Dox) on necrosis development and cell lethality of multicellular DU-145 spheroids (MCS) were examined. Multicellular spheroids consist of a peripheral rim of proliferating cells, a inner shell of nonproliferating, quiescent cells and a central core o...

journal_title：Anticancer research

authors： Wartenberg M,Acker H

更新日期：1996-03-01 00:00:00

abstract：UNLABELLED:The aim of the present study was to investigate hypoxia-inducible factor 1α (HIF-1α) and glucose transporter-1 (GLUT-1) expressions as predictors of response and survival after chemoradiotherapy in pretreatment biopsy specimens from patients with rectal cancer. MATERIALS AND METHODS:The immunohistological e...

journal_title：Anticancer research

authors： Havelund BM,Sørensen FB,Lindebjerg J,Spindler KL,Jakobsen A

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND/AIM:In breast cancer (BC) care, radiation therapy (RT) is an efficient treatment to control localized tumor. Radiobiological research is needed to understand molecular differences that affect radiosensitivity of different tumor subtypes and the response variability. The aim of this study was to analyze gene ...

journal_title：Anticancer research

authors： Minafra L,Bravatà V,Cammarata FP,Russo G,Gilardi MC,Forte GI

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND/AIM:Bevacizumab (BV) has been used for the treatment of recurrent glioblastoma. However, it also induces epithelial-mesenchymal transition (EMT) in glioblastoma cells, which compromises its efficacy. BATF2 (basic leucine zipper ATF-like transcription factor 2), a multi-target transcriptional repressor, has b...

journal_title：Anticancer research

authors： Huang W,Zhang C,Cui M,Niu J,Ding W

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND/AIM:Signaling regulation of myeloid zinc finger 1 (MZF1) has been implicated in the progression of many human malignancies; however, the mechanistic action of MZF1 in triple-negative breast cancer (TNBC) progression remains elusive. In this study, the aim was to investigate the molecular mechanisms of MZF1 a...

journal_title：Anticancer research

authors： Yue CH,Liu JY,Chi CS,Hu CW,Tan KT,Huang FM,Pan YR,Lin KI,Lee CJ

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND/AIM:Muscle relaxants, also known as neuromuscular blocking agents, can block nerve impulses to the muscles and are always used in surgery for general anesthesia. However, the effect of muscle-relaxant anesthetics on cell activity in gastric cancer is currently unknown. The present study aimed to examine and ...

journal_title：Anticancer research

authors： Jiang A,Zhao H,Liu X,Yu M,Chen J,Jiang WG

更新日期：2017-08-01 00:00:00

abstract：:Smoking is the primary factor responsible for the epidemic of squamous cell lung cancer (SqLC) and small cell lung cancer (SCLC), however, there have been few studies which reported the relationship between smoking and SCLC in female patients. To examine the relationship between smoking and SCLC and SqLC in female pat...

journal_title：Anticancer research

authors： Satoh H,Yamashita YT,Ishikawa H,Kamma H,Ohtsuka M,Sekizawa K

更新日期：1999-11-01 00:00:00

abstract：:Local control was compared between patients who had undergone breast-conserving therapy with and without nipple resection. We explored whether there was any difference in local control between the two treatment methods for patients with early breast cancer. A total of 333 women with breast cancer, who had undergone br...

journal_title：Anticancer research

authors： Horiguchi J,Koibuchi Y,Iijima K,Yoshida T,Takata D,Rokutanda N,Nagaoka R,Oyama T,Iino Y,Sakurai H,Morishita Y

更新日期：2005-07-01 00:00:00

abstract：:Thirty-five (34 evaluable) consecutive postmenopausal women with estrogen receptor positive (greater than or equal to 10 fmol/mg) or unknown advanced breast cancer were treated with high dose toremifene in a phase II study. All patients had progressed during prior adjuvant or palliativ antiestrogen treatment. The dose...

journal_title：Anticancer research

authors： Jönsson PE,Malmberg M,Bergljung L,Ingvar C,Ericsson M,Ryden S,Nilsson I,Terje IJ

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:Although oncological results for resection of colon cancer with inferior mesenteric artery (IMA) ligation at its origin (high tie) or immediately below the left colic artery (low tie) are similar, injury of the superior hypogastric plexus may be caused when the IMA is tied at its origin, thus impairing defec...

journal_title：Anticancer research

authors： Fiori E,Crocetti D,Lamazza A,DE Felice F,Scotti GB,Sterpetti AV,Mingoli A,Sapienza P,DE Toma G

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Epidemiological data suggest a more favorable outcome of breast carcinoma in women taking cardiac glycosides. This study investigated whether digoxin could inhibit tumor growth in mice. MATERIALS AND METHODS:Tumor growth experiments were done in mice grafted with the neuroblastoma cell lines SH-SY5Y, Neuro-...

journal_title：Anticancer research

authors： Svensson A,Azarbayjani F,Bäckman U,Matsumoto T,Christofferson R

更新日期：2005-01-01 00:00:00

abstract：:Recently hormone - dependent mammary carcinoma cell lines were shown to exhibit in vitro significantly lower protein kinase C (PKC) activities and epidermal growth factor receptor (EGF-R) as compared to hormone - independent cell lines. Measurements of EGF-R levels in primary human breast cancer biopsies were determin...

journal_title：Anticancer research

authors： Wyss R,Fabbro D,Regazzi R,Borner C,Takahashi A,Eppenberger U

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:Cyclooxygenase-2 (COX-2) has been reported to play an important role in the pathogenesis of a variety of cancers. Little is known about the relationship between bile duct cancer associated with pancreaticobiliary maljunction (PBM) and COX-2. MATERIALS AND METHODS:We compared the expression of COX-2 in bile ...

journal_title：Anticancer research

authors： Watanabe O,Yoshimatsu K,Shiozawa S,Tsuchiya A,Oshibe N,Aiba M,Ogawa K

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND/AIM:Even though prostate cancer (PCa) has good prognosis, there is a discrepancy in the risk among ethnic groups, with high morbidity in African American men. Single nucleotide polymorphisms (SNPs) in interleukin 10 (IL-10) have been associated with inflammation and cancer risk. We investigated the associati...

journal_title：Anticancer research

authors： Abbas M,Mason T,Ibad A,Khraiwesh M,Apprey V,Kanaan Y,Wilson B,Dunston G,Ricks-Santi L,Brim H

更新日期：2020-01-01 00:00:00

abstract：:Analysis of the overall patterns of gene expression at the polypeptide synthesis level has revealed two S-phase specific, proliferation sensitive nuclear proteins [cyclin (PCNA) and dividin (phosphoprotein)] whose rate of synthesis increases at the G1/S transition border of the cell cycle. All available evidence sugge...

journal_title：Anticancer research

authors： Celis JE,Madsen P,Nielsen S,Rasmussen HH

更新日期：1987-07-01 00:00:00