Histopathologic findings in thickened endometria, as measured by ultrasound in asymptomatic, postmenopausal breast cancer patients on various adjuvant treatment including tamoxifen.

abstract：BACKGROUND:We evaluated the effect of in vivo electrogene therapy (EGT), a newly-developed gene transfer method using electroporation on the induction of anti-cancer immunity. MATERIALS AND METHODS:The in vivo EGT was carried out by direct injection of plasmid DNAs encoding mouse interleukin-2 (IL-2) and granulocyte-m...

journal_title：Anticancer research

authors： Chi CH,Wang YS,Lai YS,Chi KH

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND/AIM:4H-1-Benzopyran-4-ones (chromones) have provided backbone structure for the chemical synthesis of potent anticancer drugs. In this study, the cytotoxicity of fifteen 2-(N-cyclicamino)chromone derivatives was investigated and subjected to quantitative structure-activity relationship (QSAR) analysis. MATE...

journal_title：Anticancer research

authors： Shi H,Nagai J,Sakatsume T,Bandow K,Okudaira N,Sakagami H,Tomomura M,Tomomura A,Uesawa Y,Takao K,Sugita Y

更新日期：2018-07-01 00:00:00

abstract：:The value of metabolic proton NMR spectroscopic imaging to detect and classify tumours increases with the spatial resolution and the information content of the spectra. Several factors influencing these quantities are discussed. ...

journal_title：Anticancer research

authors： Bovée WM,Karlsen OT,Rozijn TH

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:The proportion of geriatric gastric cancer (GC) patients with comorbidities has been increasing in Japan. This study was designed to evaluate the prognostic influence of the extent of lymph node dissection (END) and perioperative morbidities in patients with GC. PATIENTS AND METHODS:Between 2008 and 2013, t...

journal_title：Anticancer research

authors： Kawaguchi T,Komatsu S,Ichikawa D,Kimura YU,Komiyama S,Konishi H,Kin S,Kawakami S,Kosuga T,Okamoto K,Otsuji E

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND/AIM:Several studies have revealed an association between single nucleotide polymorphisms (SNPs) in the VDR gene and prostate cancer (PCa) risk in European and Asian populations. To investigate whether VDR SNPs are associated with PCa risk in African-American (AA) men, nine VDR SNPs were analyzed in a case-co...

journal_title：Anticancer research

authors： Jingwi EY,Abbas M,Ricks-Santi L,Winchester D,Beyene D,Day A,Naab TJ,Kassim OO,Dunston GM,Copeland RL Jr,Kanaan YM

更新日期：2015-03-01 00:00:00

abstract：:Adult lymphoblastic lymphoma (LBL) can be of T-cell or B-cell lineage. However, the clinical significance of immunophenotypes is largely unknown. We conducted a retrospective study to compare T-cell LBL with its B-cell counterpart. Between 1983 and 1995, 50 adult patients were diagnosed as LBL at National Taiwan Unive...

journal_title：Anticancer research

authors： Yeh KH,Cheng AL,Su IJ,Lin MT,Tien HF,Shen MC,Wang CH,Chen YC

更新日期：1997-05-01 00:00:00

abstract：AIM:The aim of the present study was to evaluate the correlation between WT1 expression levels and clinical features, to investigate the prognostic value of WT1 expression and to use lentiviral constructs to examine whether overexpression of WT1 affects cell proliferation and invasion in ovarian cancer patients. MATER...

journal_title：Anticancer research

authors： Liu Z,Yamanouchi K,Ohtao T,Matsumura S,Seino M,Shridhar V,Takahashi T,Takahashi K,Kurachi H

更新日期：2014-05-01 00:00:00

abstract：:Plastins are members of a family of actin-binding proteins which exhibit a tissue-specific expression pattern. L-plastin, which is specifically expressed in hematopoietic cell lineage, has been proposed to be involved in the control of cell adhesion and motility. This protein is also frequently expressed in cell lines...

journal_title：Anticancer research

authors： Lapillonne A,Coué O,Friederich E,Nicolas A,Del Maestro L,Louvard D,Robine S,Sastre-Garau X

更新日期：2000-09-01 00:00:00

abstract：:The significance of time interval for administration of a second drug after a first dose of cyclophosphamide (CTX) was studied for a human ovarian, lung, and colon carcinoma line growing as xenografts in nude mice. The effects of combination of two drugs were found to be dependent on the interval between the administr...

journal_title：Anticancer research

authors： Mattern J,Wauss K,Volm M

更新日期：1985-03-01 00:00:00

abstract：:Considerable progress has recently been achieved in understanding the pathogenesis of human immunodeficiency virus type 1 (HIV-1), and in improving the efficacy of antiretroviral therapies for the treatment of patients with the acquired immunodeficiency syndrome (AIDS). The pharmacological properties of new drugs are ...

journal_title：Anticancer research

authors： Romano G,Massi D,Giordano A

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Prostate cancer metastases to bone are associated with significant morbidity and mortality. Presently, there is little known about the biological interaction between prostate cancer cells and bone. Development of an animal model using adult human bone will enhance our ability to study the biology of prostate...

journal_title：Anticancer research

authors： Tsingotjidou AS,Zotalis G,Jackson KR,Sawyers C,Puzas JE,Hicks DG,Reiter R,Lieberman JR

更新日期：2001-03-01 00:00:00

abstract：:The relationship between antioxidant-enzyme defence responses and cellular growth suppression in human MCF-7 (breast) and SW480 (colon) cancer cells, exposed to CLA in culture was studied. MCF-7 and SW480 cells (1 x 10(6)/flask) were cultured in appropriate medium for 4, 8 and 12 days with varying levels of CLA (0-30 ...

journal_title：Anticancer research

authors： O'Shea M,Stanton C,Devery R

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Despite many years of clinical research and development, nausea and vomiting remain challenging toxicities related to chemotherapy. The aim of our study was to clarify the significance of non-pharmacological, patient-related risk factors for chemotherapy-induced nausea and vomiting. Furthermore, we aimed to ...

journal_title：Anticancer research

authors： Rittmeister H,Oskay-Özcelik G,Richter R,Sehouli J,Grabowski JP

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND/AIM:Cabazitaxel is an approved second-line treatment for docetaxel-refractory metastatic castration-resistant prostate cancer. However, the median time to progression on cabazitaxel is 2.8 months. We aimed to determine whether DNA methylation plays a role in cabazitaxel resistance. MATERIALS AND METHODS:DU1...

journal_title：Anticancer research

authors： Ramachandran K,Speer C,Nathanson L,Claros M,Singal R

更新日期：2016-01-01 00:00:00

abstract：:The effects induced by a low dose cyclophosphamide treatment (CPA) along with an attempt of estradiol-17-beta (E2) cell recruitment, on the bioenergetics and the phosphomonoesters/phosphodiesters (PME/PDE) ratio in the transplantable MXT mouse mammary tumor have been studied by 31P-NMR spectroscopy in vivo. Our result...

journal_title：Anticancer research

authors： Scheiber C,Kiss R,De Launoit Y,Frühling J

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND/AIM:Medullary thyroid cancer (MTC) is highly malignant, metastatic and recurrent, remaining generally incurable, and responsible for approximately 14% of all thyroid carcinoma-related deaths. MTC can metastasize to lymph nodes, trachea and distant organs, such as brain, lungs, liver and bones. MTC cells are ...

journal_title：Anticancer research

authors： Damaskos C,Garmpis N,Valsami S,Spartalis E,Antoniou EA,Tomos P,Karamaroudis S,Zoumpou T,Pergialiotis V,Stergios K,Michaelides C,Kontzoglou K,Perrea D,Nikiteas N,Dimitroulis D

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND/AIM:Exposure of organs at risk with prostate radiotherapy (RT) is lower in the prone position. This study is a prospective evaluation of setup accuracy, side-effects, and quality of life (QOL) during and after prone positioned RT. PATIENTS AND METHODS:Image-guided (IG) intensity-modulated (IM) RT was admini...

journal_title：Anticancer research

authors： Varga L,Kószó RL,Fodor E,Cserháti A,Varga Z,Darázs B,Kahán Z,Hideghéty K,Borzási E,Szabó D,Müllner K,Maráz A

更新日期：2018-06-01 00:00:00

abstract：:The immune system is part of the homeostasis system. Our research is focused on ways to maintain health, with an emphasis on the role of macrophages. We have hypothesized that tissue macrophages form a systemic network which we believe contributes to the homeostasis system, and have named it the 'macrophage network.' ...

journal_title：Anticancer research

authors： Taniguchi Y,Yoshioka N,Nishizawa T,Inagawa H,Kohchi C,Soma G

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Positron emission tomography-computed tomography (PET-CT) is currently not established in the management of recurrent ovarian cancer. Here, its value in diagnosis and therapy planning was evaluated. PATIENTS AND METHODS:Seventy patients received PET-CT for suspicion of recurrent ovarian cancer. PET-CT and s...

journal_title：Anticancer research

authors： Lenhard MS,Burges A,Johnson TR,Stieber P,Kümper C,Ditsch N,Linke R,Friese K

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the role of radiation therapy alone, employing standard fractionation, in stage III-IV hypopharyngeal carcinoma. MATERIALS AND METHODS:Fourteen (38.9%) stage III and 22 (61.1%) stage IV patients with hypopharyngeal carcinoma were submitted, with curative intent, to excl...

journal_title：Anticancer research

authors： Tombolini V,Santarelli M,Raffetto N,Donato V,Valeriani M,Ferretti A,Enrici RM

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Pathological examination of sentinel lymph nodes (SLNs) and non-SLNs in colon cancer is frequently not performed to the same extent. We examined whether non-SLNs were truly negative in tumors with tumor-negative SLNs using reverse transcriptase-polymerase chain reaction (RT-PCR). PATIENTS AND METHODS:RT-PCR...

journal_title：Anticancer research

authors： Kelder W,Braat A,van den Berg A,Platteel I,Hollema H,Groen H,Plukker J

更新日期：2007-07-01 00:00:00

abstract：AIM:To assess the correlation between advanced non-small cell lung cancer (NSCLC) with or without pulmonary lymphangitic carcinomatosis (PLC) and fluorodeoxyglucose (FDG) uptake and its effect on survival outcomes. PATIENTS AND METHODS:We retrospectively reviewed 157 patients with NSCLC. The mean and maximum standardi...

journal_title：Anticancer research

authors： Ooi H,Chen CY,Hsiao YC,Huang WS,Hsieh BT

更新日期：2016-08-01 00:00:00

abstract：:Bone-seeking radionuclides have been used to treat bone pain due to metastatic bone disease for over 40 years. More than 10 clinical studies using radiostrontium (Sr-89) have shown benefit in about 70-80% of patients having refractory bone pain from prostate, breast and other metastatic bone cancers, with minimal hema...

journal_title：Anticancer research

authors： Kim SI,Chen DC,Muggia FM

更新日期：1988-07-01 00:00:00

abstract：:Methyl-tertiary-butyl ether (MTBE) is a ubiquitous oxygen-bearing additive used to reduce engine knocking and obtain cleaner gasoline combustion. Conflicting data have been reported about a possible carcinogenic role of MTBE in humans. In this study we evaluated the effects of MTBE on cell growth and transformation in...

journal_title：Anticancer research

authors： Iavicoli I,Carelli G,Ardito R,Cittadini A,Sgambato A

更新日期：2002-07-01 00:00:00

abstract：:Evidence from our laboratory suggests that conventional chromosome banding analysis alone is not sufficient for detecting interspecies contamination of cell lines. To differentiate noncycling interphase cells of murine or other species origin that may be contaminating a human cell line, molecular cytogenetic technique...

journal_title：Anticancer research

authors： Multani AS,Pathak S

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Lung cancer tissues are often infiltrated by B lymphocytes, but it is not clear whether these infiltrations represent tumor-specific immune response or a nonspecific reaction. MATERIALS AND METHODS:The serological analysis of recombinant cDNA expression libraries (SEREX) were previously modified using a sev...

journal_title：Anticancer research

authors： Yasuda M,Mizukami M,Hanagiri T,Shigematsu Y,Fukuyama T,Nagata Y,So T,Ichiki Y,Sugaya M,Takenoyama M,Sugio K,Yasumoto K

更新日期：2006-09-01 00:00:00

abstract：:Telomeres, the tandem-repeated hexamers at the termini of mammalian chromosomes, form protective complexes in association with specific proteins that together with telomerase, a specialised telomere-synthesizing enzyme, regulate telomere length. Telomere shortening is associated with cellular senescence and is implica...

journal_title：Anticancer research

authors： Bekaert S,De Meyer T,Van Oostveldt P

更新日期：2005-07-01 00:00:00

abstract：:Chk1 (checkpoint kinase 1) is a serine-threonine kinase that is critical for G2/M arrest in response to DNA damage. Chk1 phosphorylates Cdc25C at serine-216, a major regulatory site, in response to DNA damage. Furthermore, Chk1 also phosphorylates Cdc25A on serine 123 which accelerates its degradation through the ubiq...

journal_title：Anticancer research

authors： Han EK,Butler C,Zhang H,Severin JM,Qin W,Holzman TF,Gubbins EJ,Simmer RL,Rosenberg S,Giranda VL,Ng SC,Luo Y

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND/AIM:Curcumin is a promising nutraceutical for chemoprevention of head and neck squamous cell carcinoma (HNSCC). Capsular formulations of curcumin demonstrate low systemic bioavailability. We aimed to determine if curcumin levels were higher in healthy volunteers and cancer patients with microgranular curcumi...

journal_title：Anticancer research

authors： Latimer B,Ekshyyan O,Nathan N,Moore-Medlin T,Rong X,Ma X,Khandelwal A,Christy HT,Abreo F,McClure G,Vanchiere JA,Caldito G,Dugas T,McMartin K,Lian T,Mehta V,Nathan CA

更新日期：2015-12-01 00:00:00

abstract：:1-(phenylmethyl)-4,7,10-tris-[(4'methylphenyl)-sulfonyl]-1,4,7, 10-tetraazacyclododecane proved to possess potent in vivo antineoplastic and in vitro cytotoxicity in murine and human tissue cultured cells. In Tmolt3 leukemic cells 1-(phenylmethyl)-4,7,10-tris-[(4'methylphenyl)sulfonyl]-1,4,7, 10-tetraazacyclododecane ...

journal_title：Anticancer research

authors： Hall IH,Elkins AL,Karthikeyan S,Spielvogel BF

更新日期：1997-03-01 00:00:00