Abstract:
:Distinct structural features of DNA, such as the curvature of dA tracts, are important in the recognition, packaging, and regulation of DNA. Physiologically relevant concentrations of magnesium have been found to enhance the curvature of dA tract DNAs, as monitored by solution-state NMR, indicating that the structure of DNA depends on the cations present in solution. A model is presented which accounts for the sequence-dependent effects of magnesium on DNA curvature as well as for the previously known sequence-independent effect on DNA flexibility.
journal_name
Biochemistryjournal_title
Biochemistryauthors
Jerkovic B,Bolton PHdoi
10.1021/bi010853jsubject
Has Abstractpub_date
2001-08-07 00:00:00pages
9406-11issue
31eissn
0006-2960issn
1520-4995pii
bi010853jjournal_volume
40pub_type
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