Abstract:
:The degree of chromosome damage induced by three compounds of zinc (zinc chloride, zinc sulfate, zinc acetate) was compared in human leucocytes in vitro. Three concentrations of each salt, 3.0 x 10(-5)M, 3.0 x 10(-4)M, and 1.5 x 10(-3)M, were added to leukocyte cultures. The cells were harvested after 48 and 72 h and chromosome spreads were prepared following a colchicine-hypotonic-fixation-air drying-Giemsa staining schedule. The end point screened was chromosome aberrations. All three salts were lethal at the highest concentration. The degree of chromosome damage was directly proportional to the concentrations used for zinc sulfate and zinc acetate but not for zinc chloride.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Santra M,Talukder G,Sharma Adoi
10.1385/BTER:78:1-3:113subject
Has Abstractpub_date
2000-01-01 00:00:00pages
113-9issue
1-3eissn
0163-4984issn
1559-0720pii
BTER:78:1-3:113journal_volume
78pub_type
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