Abstract:
:Studies were designed to characterize the plasma membrane polypeptide composition of normal rat kidney (NRK) and virus-transformed NRK cells as a function of time following iron deprivation. Using this approach we found that rapid depletion of iron from the cells increases the amounts of two membrane-associated glycoproteins of apparent MW 160,000 (160 K) and 130,000 (130 K) in NRK cells. In contrast, virus-transformed NRK cells subjected to iron deprivation showed an altered induction phenomenon manifested by reduced levels of both 160 K and 130 K and altered time-sequence of the induction. Possible relationship of the 160 K and 130 K membrane-associated glycoproteins described in this study to growth control and viral transformation are discussed.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Fernandez-Pol JAdoi
10.1007/BF02821711subject
Has Abstractpub_date
1979-06-01 00:00:00pages
157-68issue
2eissn
0163-4984issn
1559-0720journal_volume
1pub_type
杂志文章abstract::Studies have evidenced that zinc metabolism is altered in presence of Down syndrome, and zinc seems to have a relationship with the metabolic alterations usually present in this syndrome. In this work, the Zn-related nutritional status of adolescents with Down syndrome was evaluated by means of biochemical parameters ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-007-0061-5
更新日期:2007-01-01 00:00:00
abstract::The causes of night blindness in children are multifactorial, and particular consideration has been given to childhood nutritional deficiency, which is the most common problem found in underdeveloped countries. Such deficiency can result in physiological and pathological processes that in turn influence hair compositi...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8789-8
更新日期:2011-09-01 00:00:00
abstract::Fluoride (F) concentration in blood serum of healthy dromedary camel population was measured, and its relationship with age and sex was determined. In male animals, the level varied from 0.017 to 0.296 ppm, with mean (± S.E.) value of 0.163 ± 0.013 ppm. In females, the level varied from 0.036 to 0.372 ppm with mean va...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02534-9
更新日期:2021-01-06 00:00:00
abstract::The present study was conducted to investigate whether the combined treatment with Se and Zn offers more beneficial effects than that provided by either of them alone in reversing Cd-induced oxidative stress in the kidney of rat. For this purpose, 30 adult male Wistar albino rats, equally divided into control and four...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8324-y
更新日期:2009-08-01 00:00:00
abstract::This study was designed to investigate the effects of chromium methionine (Cr-Met) on glucose metabolism, blood metabolites, meat lipid peroxidation, and tissue chromium (Cr) in Mahabadi goat kids. Thirty-two male kids (16.5 ± 2.8 kg BW, 4-5 months of age) were fed for 90 days in a completely randomized design with fo...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0190-6
更新日期:2015-03-01 00:00:00
abstract::The present investigation was carried out to determine the molybdenum (Mo) status of blood plasma and milk of lactating cows at the Livestock Experimental Station, Khizer abad, Sargodha, Pakistan. Blood and milk from the lactating cows were sampled periodically after every month during winter so as to examine the effe...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8874-z
更新日期:2011-10-01 00:00:00
abstract::It has become evident over the last two decades that there is an intimate relationship between the trace elements and cancer. Some trace elements have been shown to be carcinogens, others appear to provide protection against cancer. Profound changes in trace element concentrations and distribution occur in patients wi...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783817
更新日期:1979-08-01 00:00:00
abstract::This study was undertaken to evaluate a systematic analysis of mineral and trace elements of individual functionally determined parts of adult temporal bone. Marked differences were observed in basic structural elements (Ca, P, Mg, and Zn) among different bone regions. The more so, molar Ca/P ratio was significantly d...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF03032672
更新日期:1991-04-01 00:00:00
abstract::The new range of sealed-tube neutron generators developed by SODERN appears to be appropriate for the industrial environment. The main characteristics are the high emission stability during the very long lifetime of the tube, flexible pulsed mode capability, safety in operation with no radiation in "off" state, and th...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917309
更新日期:1994-10-01 00:00:00
abstract::Hyperlipidemia is one of the major risk factors for atherosclerosis and ischemic heart disease. Chromium (Cr) mineral is playing a crucial role in glucose and lipid homeostasis. The aim of this study was to evaluate the protective effects of combined chromium picolinate (CrPic) and atorvastatin treatment against hyper...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1010-6
更新日期:2017-12-01 00:00:00
abstract::This study was performed to determine the effects of selenium supplementation on clinical symptoms and gene expression related to inflammatory markers in infertile women with polycystic ovary syndrome (PCOS) who were candidate for in vitro fertilization (IVF). Thirty-six women candidate for IVF were recruited in this ...
journal_title:Biological trace element research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12011-019-01715-5
更新日期:2020-02-01 00:00:00
abstract::Selenium and methylmercuric chloride (MMC) interactions regarding cellular uptake and selenium protection on MMC toxicity have been studied. Human K-562 cells were pretreated or simultaneously treated with either selenite (5 or 50 microM) or selenomethionine (10 or 50 microM) together with (3.5 or 5 microM) MMC. Cells...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:80:3:251
更新日期:2001-06-01 00:00:00
abstract::Endemic waterborne fluorosis is a public health problem in Isparta, a city located in southern Turkey. Fluoride is a cumulative element that increases metabolic turnover of the bone and also affects the homeostasis of bone mineral metabolism. There are number of similarities between the effects of excess parathyroid h...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8847-2
更新日期:2011-10-01 00:00:00
abstract::Methylmercury (MeHg) is highly toxic, and its principal target tissue in human is the nervous system, which has made MeHg intoxication a public health concern for many decades. Portulaca oleraceae (purslane), a member of the Portulacaceae family, is widespread as a weed and has been ranked the eighth most common plant...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0546-6
更新日期:2016-07-01 00:00:00
abstract::This study concerns application of flame atomic absorption spectrometry (FAAS) in assessment of macro- and microelement and toxic metal levels (Mg, Ca, K, Na, Mn, Cu, Fe, Zn, Cr, Ni, Co, Cd and Pb) in dark (Pu-erh) and fruit tea leaves and their infusions. Phosphorus was also determined in the form of phosphomolybdate...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0669-4
更新日期:2016-11-01 00:00:00
abstract::The authors present a simple and rapid method for assaying ultrafilterable copper (Cu UF) and albumin-bound copper (Cu ALB). It is based on the ultrafiltration of serum in the presence of ethylenediaminetetraacetic acid (EDTA), used to prevent adsorption on the membranes. EDTA at 0.4 g/L has no effect on the equilibri...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917499
更新日期:1988-12-01 00:00:00
abstract::Nickel is an important kind of metal and a necessary trace element in people's production and livelihood; it is also a well-confirmed human carcinogen. In the past few years, researchers did a large number of studies about the molecular mechanisms of nickel carcinogenesis, and they focused on activation of proto-oncog...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9619-6
更新日期:2013-05-01 00:00:00
abstract::The phosphorus NMR profile of normal and vanadium-treated chick muscle was obtained in vivo. The data show that the differentiation of breast and thigh muscles in terms of pH, lipid related metabolites, and bioenergetic parameters can be readily followed. Although the vanadium-treated chicks showed substantial retarda...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990427
更新日期:1991-11-01 00:00:00
abstract::Measurement and monitoring of magnesium (Mg) are important to prevent the development of serious and potentially fatal complications in critically ill patients. Although ion-selective electrodes are available and earlier reports suggest that free ionized magnesium (iMg2+) is the most useful test to estimate Mg status,...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:115:1:13
更新日期:2007-01-01 00:00:00
abstract::Body stores of lead, cadmium, and mercury are determined by the levels in the circulation, and their levels in blood may be related to hemoglobin levels and their absorption by soft tissue and bone. We investigated the association of body fat percentage, hemoglobin levels, and nutrient intakes with the blood concentra...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9566-7
更新日期:2013-03-01 00:00:00
abstract::Oxidative stress plays a crucial role in the pathogenesis of multiple sclerosis (MS). Previous studies have shown that oxidative stress is one of the main underlying mechanisms of arsenic-induced cellular damage. The aim of this study was to assess the serum levels of arsenic and its relationship with lipid peroxidati...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-9956-0
更新日期:2014-06-01 00:00:00
abstract::The effects of zinc chloride (ZnCl2), disodium zinc ethylenediamine tetraacetate (Zn-EDTA), and zinc gluconate (Zn-GLU) on the antioxidant enzyme activities and levels of interleukins (ILs) in psoriasis-induced mice were studied. One hundred twenty female mice were randomly divided into six groups with 20 mice in each...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9799-0
更新日期:2013-12-01 00:00:00
abstract::Lead poisoning is a worldwide health problem, and its treatment is under investigation. The aim of this study was to access the efficacy of Coriandrum sativum (coriander) in reducing lead-induced changes in mice testis. Animal exposed to lead nitrate showed significant decrease in testicular SOD, CAT, GSH, total prote...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8553-0
更新日期:2010-09-01 00:00:00
abstract::The solubility of both free and low molecular weight ligand complexed calcium, magnesium, and zinc in skimmed human and bovine milks over intestinal luminal pH ranges (approximately 3-7) was measured using ultrafiltration techniques. Some of the experimental difficulties associated with the separation of labile metal ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02925450
更新日期:1989-01-01 00:00:00
abstract::This study was conducted to investigate the effects of zinc sources on gene expression of zinc-related transporters in intestinal porcine epithelial cells (IPEC-1). IPEC-1 cells were treated with zinc glycine chelate (Zn-Gly), zinc methionine (Zn-Met), and zinc sulfate (ZnSO4), respectively, for measurement of cell vi...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0655-x
更新日期:2016-10-01 00:00:00
abstract::To examine longitudinal and gestational effects of mineral content in human milk, we analyzed human milk from lactating mothers of premature (PRT, n = 24, < 2000 g birth weight, < 37 wk gestation) and full-term (FT, n = 19, > 2500 g, 39-41 wk gestation), living in Newfoundland, Canada. Samples were collected once a we...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784423
更新日期:1999-03-01 00:00:00
abstract::Two trials were conducted in a 2 × 2 + 1 factorial arrangement based on a completely randomized design to evaluate the effects of different sources of selenium (Se) on performance, blood metabolites, and nutrient digestibility in male lambs on a barley-based diet. The first trial lasted for 70 days and consisted of 30...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9698-4
更新日期:2013-07-01 00:00:00
abstract::For this study, we investigate more deeply the effect calcium (Ca) develops on the mechanism underlying fluoride-triggered osteocyte apoptosis. We detected the morphology of osteocytes by HE staining, mitochondrial microstructure by using the transmission electron microscope, and the biochemical indexes related to bon...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02305-6
更新日期:2020-07-25 00:00:00
abstract::The aim of the current study was to assess relationships between multiple metals burden in human seminal plasma and semen quality parameters. Levels of five metals (lead, manganese, copper, arsenic, and selenium) in human seminal plasma were determined by inductively coupled plasma mass spectrometry (ICP-MS), and the ...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1007/s12011-012-9335-7
更新日期:2012-07-01 00:00:00
abstract::Polaprezinc (zinc L-carnosine complex) is a tablet commonly prescribed for gastric ulcers in Japan. Recently, we reported the effects of polaprezinc on pressure ulcer healing at 4-week follow-up. We aimed to further evaluate the efficacy and safety of polaprezinc in 8-week treatment for chronic pressure ulcers. Patien...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1007/s12011-014-9943-5
更新日期:2014-06-01 00:00:00