Abstract：
:The purpose of this study was to determine the dietary essentiality of lithium (Li) in rats. In three experiments, two types of diets were fed during growth, reproduction, and lactation. In the first experiment, dams were maintained on a corn-based diet containing 2 ng or 500 ng (controls) Li/g through five successive periods of pregnancy and lactation. The offspring of dams fed the low-Li diet had significantly lower weaning weights (p = 0.011), and the percent weaned was lower (p = 0.094) than that of controls. In the second experiment, rats were maintained through three generations on a rice-based diet containing 0.6 ng Li/g, or the control (500 ng/g) diet. There was a significant effect of Li level on litter size (p = 0.017) and litter wt at birth (p = 0.006) in the third generation. The overall effect through three generations on litter wt at birth approaches statistical significance (p = 0.086). In the third experiment, third-generation rats were continued on the respective rice-based diets with three levels of dietary sodium, the normal level, one-half, and four times that level. The litter size and birth wt were significantly lower (p = 0.0030 and 0.0038, respectively) among the low-Li dams that consumed the normal and high-sodium levels compared to those that consumed the low-sodium diets. The interaction of Li and sodium as regards litter wt at birth approached significance (p = 0.083). Various tissues of the rats in the third experiment were analyzed for Li. It seems likely that Li exerts an essential nutrient role for the rat.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Pickett EE,O'Dell BLdoi
10.1007/BF02783685subject
Has Abstractpub_date
1992-09-01 00:00:00pages
299-319issue
3eissn
0163-4984issn
1559-0720journal_volume
34pub_type
杂志文章abstract：:Two experiments were performed to confirm that boron interacts with calcium, and that this interaction can be modified by dietary magnesium and potassium in the rat. Upon manipulating the dietary variables listed above, it was found that under certain conditions, boron and calcium deprivation similarly affected severa...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783768
更新日期：1992-12-01 00:00:00
abstract：:Concentrations of toxic elements (lead, cadmium, mercury, and arsenic) were measured in water, sediment, and four commercial fish species (Cyprinus carpio, Hypophthalmichthys molitrix, Silurus glanis, and Esox lucius) and their tissues (muscle, liver, and kidney) from Saničani Lake, Bosnia and Herzegovina. The concent...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-019-01982-2
更新日期：2020-09-01 00:00:00
abstract：:Being a proven photocatalyst, nano-anatase is capable of undergoing electron transfer reactions under light. In previous studies, we had proven that nano-anatase improved photosynthesis and greatly promoted spinach growth. However, the molecular mechanisms of carbon reaction promoted by nano-anatase are still not clea...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-008-8203-y
更新日期：2008-01-01 00:00:00
abstract：:Selenium and mercuric chloride (MC) interactions regarding effects on cell growth and cell death have been studied. Human K-562 cells were pretreated or simultaneously treated with either selenite (5 or 50 microM) or selenomethionine (10 or 50 microM) and with MC (35 or 50 microM). The 35-microM MC treatments resulted...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:92:2:105
更新日期：2003-05-01 00:00:00
abstract：:Multivariate statistical analysis has been applied to time series measurements of aerosol elemental composition from PIXE analysis of filter samples, and principal components have been resolved that represent distinct particle types in an external mixture in the atmosphere. In this study, it is argued that a combinati...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02992673
更新日期：1990-07-01 00:00:00
abstract：:Present study investigates relationships between total and bioaccessibility of trace elements (Cd, Co, Cr, Cu, Mn, NI, Pb, V, and Zn) concentrations in sediment and their bioaccumulation in species in Shadegan wetland in southwest of Iran. Bioavailability factor (BAF) and translocation factor (TF) were calculated in p...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8795-x
更新日期：2011-09-01 00:00:00
abstract：:A dose-response experiment was conducted to find the sensitive and consistent biomarker for the estimation of dietary manganese (Mn) requirement and establish the optimal Mn level for broilers fed a practical corn-soybean meal diet from 1 to 21 days of age post-hatching. A total of 480 1-day-old Arbor Acres male chick...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8931-7
更新日期：2011-11-01 00:00:00
abstract：:The study was undertaken to investigate the influence of alpha-tocopherol on zinc, copper, iron, calcium, magnesium, and potassium concentrations in serum of rats with bleomycin-induced pulmonary fibrosis. Fourteen Wistar albino rats were randomly divided into two groups of seven animals each. The first group was trea...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:114:1:175
更新日期：2006-01-01 00:00:00
abstract：:This experiment was conducted to evaluate the effects of zinc (ZnSO4.H2O) and vitamin A (retinol) supplementation on performance, carcass characteristics, and serum concentrations of glucose, cholesterol, total protein, and malondialdehyde (MDA) as an indicator of lipid peroxidation in broiler chickens (Ross) reared a...
journal_title：Biological trace element research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1385/BTER:94:3:225
更新日期：2003-09-01 00:00:00
abstract：:In order to understand the normal and pathological physiologies of the epidermal cells, the simultaneous determination of several elements in the different cellular strata is of crucial importance. In recent years the electron microprobe (EMP) has become an established technique in this field. Its high spatial resolut...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02796687
更新日期：1987-04-01 00:00:00
abstract：:Zinc concentrations in the dorsal horn of spinal cord are important for wound healing, neurological function, and reproduction. However, the response of the spinal cord to alterations in dietary zinc is unknown in rats after spinal cord injury (SCI). The current study explored cellular zinc levels and zinc transporter...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-012-9414-9
更新日期：2012-11-01 00:00:00
abstract：:This study was designed to investigate the effects of chromium methionine (Cr-Met) on glucose metabolism, blood metabolites, meat lipid peroxidation, and tissue chromium (Cr) in Mahabadi goat kids. Thirty-two male kids (16.5 ± 2.8 kg BW, 4-5 months of age) were fed for 90 days in a completely randomized design with fo...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-0190-6
更新日期：2015-03-01 00:00:00
abstract：:The effects of zinc chloride (ZnCl2), disodium zinc ethylenediamine tetraacetate (Zn-EDTA), and zinc gluconate (Zn-GLU) on the antioxidant enzyme activities and levels of interleukins (ILs) in psoriasis-induced mice were studied. One hundred twenty female mice were randomly divided into six groups with 20 mice in each...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-013-9799-0
更新日期：2013-12-01 00:00:00
abstract：:Cadmium concentrations were determined in the hair of 226 school children in an industrial and in a rural area of Tarragona Province (NE Spain). The influence of sex, age, hair color, smoking habits of the household members, and parents' occupation on the children's hair cadmium levels was also evaluated. Children liv...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02863080
更新日期：1991-02-01 00:00:00
abstract：:The objective of this study was to assess the contamination levels of arsenic (As), lead (Pb), chromium (Cr), and cadmium (Cd) in raw milk and the subsequent potential health risk to local consumers close to leather-processing plants in China. The As and Pb concentrations in milk from contaminated areas were 0.43 ± 0....
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02470-8
更新日期：2020-11-12 00:00:00
abstract：:The developmental alterations in metallothionein (MT) proteins and zinc (Zn) were investigated in brains of two transgenic strains of mice. MT protein was measured by a cadmium binding assay and Zn by atomic absorption spectrophotometry. MT proteins were expressed at birth (day 1) both in MT-I overexpressing transgeni...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02784039
更新日期：1998-01-01 00:00:00
abstract：:Because nickel may have a biological function in a pathway in which vitamin B12 is important, an experiment was performed to determine the effects of nitrous oxide exposure in rats deprived of nickel. Exposure to nitrous oxide (N2O) causes inactivation of cobalamin and a subsequent decrease in the vitamin B12-dependen...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783980
更新日期：1993-07-01 00:00:00
abstract：:Comparison of the clastogenic effects of antimony and bismuth used as trioxides, when administered orally by gavaging to laboratory bred male mice, showed that the former was more strongly clastogenic than the latter. Three doses of each chemical (400, 666.67, and 1000 mg/kg body wt), corresponding to 1/50, 1/30, and ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783802
更新日期：1993-05-01 00:00:00
abstract：:This study was conducted to investigate the effect of zinc chitosan chelate (CS-Zn) on zinc transporter expression and content of tissue zinc in weaned piglets. A total of 90 weaned pigs (Duroc × Landrace × Yorkshire) were randomly allocated to treatment groups with supplementation of 100 mg/kg zinc as ZnSO4, 100 mg/k...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-016-0732-1
更新日期：2016-12-01 00:00:00
abstract：:In the present study, the conditions of analysis by inductively coupled plasma-atomic emission spectrometry (ICP-AES) were investigated. Twenty-six elements (Mg: 25 ppm; Sc: 10 ppm; Ti: 50 ppm; others: 100 ppm) were used as the elements interfering with selected 24 wavelengths. Consequently, the background values in 1...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:87:1-3:211
更新日期：2002-07-01 00:00:00
abstract：:This study evaluated the plasma levels of trace elements in children with chronic hepatitis B virus (HBV) infection and assessed whether they can be a factor that affects the response to interferon alpha (IFN-alpha) treatment. The study included 35 cases (ten girls, 25 boys) aged 3-13 years with chronic HBV infection ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-009-8507-6
更新日期：2010-06-01 00:00:00
abstract：:Experiments were conducted to determine whether the increased glutathione S-transferase (GSH-T) activity associated with selenium (Se) deficiency is necessarily related to losses in the activity of Se-dependent glutathione peroxidase (SeGSHpx) in chicks. Nutritional Se status was altered in two ways: by treatment with...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783792
更新日期：1993-05-01 00:00:00
abstract：:The intervention effect of fucoxanthin, which is reportedly a powerful antioxidant, on cadmium-induced thyroid damage in mice was evaluated. Animals (N = 120) were divided into control group (given pure water, N = 20) and CdCl2-exposed group (given CdCl2 orally at a dose of 30 mg/kg body weight (bw)/day for 30 days, N...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02291-9
更新日期：2020-07-21 00:00:00
abstract：:Two 42-d experiments were conducted with weanling male rats to study interactions between nickel and copper. In Experiment 1, a low-copper basal diet was supplemented with copper at 0 or 30 ppm and nickel at 0 or 30 ppm. Copper was added in Experiment 2 to a basal copper-deficient diet at a level of 0 or 15 ppm and ni...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02916540
更新日期：1985-04-01 00:00:00
abstract：:In a controlled animal experiment the effects of dietary subacute Zn deficiency on growth, Zn concentration, and tissue 42-K distribution were studied. Growth retardation caused lower body weight because both skeletal and heart muscle showed a reduction in cell mass. Zn concentrations were reduced in most tissues, how...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02789301
更新日期：1994-12-01 00:00:00
abstract：:Scleroderma, sclerosis of the skin, is a severe autoimmune disease refractant to all kind of treatments. To study the in vivo effects of a combination of three oligoelements selenium (Se), zinc (Zn), and manganese (Mn) plus Lachesis muta venom (O-LM) on the bleomycin (BLM)-induced scleroderma mouse experimental model....
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-013-9876-4
更新日期：2014-02-01 00:00:00
abstract：:Ferritin levels have been associated with metabolic syndrome and insulin resistance. The aim of the present study was to evaluate the prediction of ferritin levels by variables related to cardiometabolic disease risk in a multivariate analysis. For this aim, 123 healthy women (72 premenopausal and 51 posmenopausal) we...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-012-9351-7
更新日期：2012-08-01 00:00:00
abstract：:We investigated the effect of magnesium supplementation on zinc distribution in rats given excess calcium as carbonate. Rats were given a control diet (5 g/kg calcium and 0.5 g/kg magnesium), a high calcium diet (HC, 25 g/kg calcium and 0.5 g/kg magnesium) or the high calcium diet supplied with magnesium (HCM, 25 g/kg...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-008-8166-z
更新日期：2008-11-01 00:00:00
abstract：:The effect of zinc deficiency on calmodulin function was investigated by assessing the in vivo activity of two calmodulin regulated enzymes, adenosine 3',5'-monophosphate (c-AMP) and guanosine 3',5'-monophosphate (c-GMP) phosphodiesterase (PDE) in several rat tissues. Enzymatic activities in brain, heart, and testis o...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02797137
更新日期：1988-08-01 00:00:00
abstract：:The molecular localization of maternal and fetal zinc and copper metalloproteins in diabetic and control rats was studied. Compared to controls, liver and kidneys of diabetic dams showed an increased concentration of zinc and copper that was associated with metallothionein. In contrast, fetuses of diabetic dams had lo...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02917490
更新日期：1988-12-01 00:00:00
