Dissecting the energy needs of the body.

abstract：PURPOSE OF REVIEW:To summarize recent findings that docosahexaenoate (DHA) is the precursor of stereospecific derivatives with anti-inflammatory and cytoprotective properties. RECENT FINDINGS:The docosahexaenoate-derived mediator neuroprotectin D1 is formed in retinal pigment epithelial cells when confronted with oxid...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Bazan NG

更新日期：2007-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Dietary fiber and prebiotics have been the focus of research and discussion for decades, but there are still pending concepts and definitions, in particular when addressing their use in the prevention and treatment of diarrhea. The purpose of this review is to present the latest advances in the unders...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Generoso SV,Lages PC,Correia MITD

更新日期：2016-09-01 00:00:00

abstract：:Lipids play an extraordinary range of roles in normal and deranged metabolism. In diabetes and obesity, lipids have often been seen just as impacting on the energy balance equation. New data are extending our understanding of how lipid subclasses influence carbohydrate and lipid metabolism at multiple control points: ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Storlien LH,Hulbert AJ,Else PL

更新日期：1998-11-01 00:00:00

abstract：:Despite a large number of published randomized prospective controlled clinical trials the indications for perioperative parenteral and enteral nutrition support remain controversial. This article reviews the reports of several recently published consensus conference reports and prospective randomized controlled trials...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Satyanarayana R,Klein S

更新日期：1998-01-01 00:00:00

abstract：:The K vitamins, a group of napthoquinones, are required for the carboxylation of a limited number of proteins including the bone matrix protein osteocalcin. Vitamin K1 (phylloquinone) and vitamin K2 (menaquinones), differ regarding food source (green vegetables and fermented products, respectively), bioavailability an...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Zittermann A

更新日期：2001-11-01 00:00:00

abstract：:The impairment of transsulphuration during methionine degradation in hepatic failure can be counteracted by treatment with S-adenosylmethionine. Regarding the pathogenesis of hepatic encephalopathy, no convincing evidence exists for tryptophan, glutamine or glutamate being involved. Portal-systemic shunting-induced hy...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Holm E,Sedlaczek O,Grips E

更新日期：1999-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Lipidomic profiling of biological samples is increasing in nutritional research applications. 'Lipidomic analyses' however can be quite variable in specific methods and the type of information about the specific lipids that is revealed. The lack of defined and simple terminology to describe aspects of...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Aristizabal Henao JJ,Bradley RM,Duncan RE,Stark KD

更新日期：2018-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Obesity continues to increase around the globe, and creates a major health problem because of its comorbidities such as diabetes and cardiovascular disease. Considering that the major cause of most human obesities is the modern lifestyle in a rapidly changing environment, this suggests that the battle...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Berthoud HR

更新日期：2003-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to provide a concise overview of the polyphenol curcumin for improving arterial health, specifically endothelial function and arterial stiffness, to reduce cardiovascular disease (CVD) risk and to highlight potential mechanisms of action by which curcumin may improve arte...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Fleenor BS,Carlini NA,Campbell MS

更新日期：2019-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Size at birth is critical in determining life expectancy with both small and large neonates at risk of shortened life spans. This review examines the hormonal and nutritional drivers of intrauterine growth with emphasis on the role of foetal hormones as nutritional signals in utero. RECENT FINDINGS:N...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Sferruzzi-Perri AN,Vaughan OR,Forhead AJ,Fowden AL

更新日期：2013-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The major components of ERAS attenuate the inflammatory response and modulate metabolism in direction of sparing body protein and preserving function. However, these perioperative interventions might have limited effectiveness on postoperative outcomes if preoperative risk factors are not addressed an...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Chabot K,Gillis C,Carli F

更新日期：2020-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Skeletal muscle and lean body mass may be vital to prognosis and functional recovery in chronic and acute illness, particularly in conditions in which muscle atrophy is prevalent. Ultrasound provides a precise and expedient method to measure muscle mass and changes in skeletal muscle at the bedside. ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Mourtzakis M,Wischmeyer P

更新日期：2014-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Malnutrition is prevalent in critically ill patients and is linked to worse outcomes such as prolonged mechanical ventilation, length of intensive care unit (ICU) stay, and increased mortality. Therefore, nutritional therapy is important. However, it is often difficult to accurately identify those at ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Dong V,Karvellas CJ

更新日期：2020-12-05 00:00:00

abstract：:Food products have variously been reported as causing, perpetuating or treating irritable bowel syndrome. The evidence for this is reviewed with regard to recent studies investigating symptom reporting, mono- and disaccharide malabsorption and probiotics. The development of objective measures remains an urgent priorit...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Dunlop SP,Spiller RC

更新日期：2001-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The objective of this review has been to analyse and compare the causes, incidence, severity and treatment of gastrointestinal complications in critically ill children and adults. RECENT FINDINGS:The incidence of gastrointestinal complications in critically ill patients published in the literature is...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： López-Herce J

更新日期：2009-03-01 00:00:00

abstract：:Drug-nutrient interactions have been recognized for decades. It is known that improper management of some of these interactions may lead to therapeutic failure or cause serious adverse effects to the patients. While most of the known drug-nutrient interactions involve changes in oral bioavailabilities and absorption o...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Chan LN

更新日期：2002-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Folic acid is now considered an important functional food component: it lowers potentially toxic homocysteine, prevents birth defects and modulates the risk of several cancers. The complexity of interactions involved, however, means we still have much to learn about the role of folate and homocysteine...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Lucock MD

更新日期：2006-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Epigenetics has emerged in recent years as one of the most important biological mechanisms linking exposures across the life course to long-term health. This article reviews recent developments in our understanding of the metabolic and genetic determinants of epigenetic variation in human populations....

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Haggarty P

更新日期：2015-07-01 00:00:00

abstract：PURPOSE OF REVIEW:There has been growing evidence that lifestyle factors may affect the health and lifespan of an individual by affecting telomere length. The purpose of this review was to highlight the importance of telomeres in human health and aging and to summarize possible lifestyle factors that may affect health ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Shammas MA

更新日期：2011-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Ketone body metabolism is a dynamic and integrated metabolic node in human physiology, whose roles include but extend beyond alternative fuel provision during carbohydrate restriction. Here we discuss the most recent observations suggesting that ketosis coordinates cellular function via epigenomic reg...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ruan HB,Crawford PA

更新日期：2018-07-01 00:00:00

abstract：:Arginine is a non-essential amino acid in mammals as judged from nitrogen balance study. Citrulline is synthesized from glutamate in the small intestine, whilst kidneys and some other tissues convert citrulline to arginine. Ornithine transcarbamylase and carbamylphosphate synthetase are expressed in liver and small in...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Wakabayashi Y

更新日期：1998-07-01 00:00:00

abstract：PURPOSE OF REVIEW:L-Arginine is the precursor for nitric oxide synthesis. In the brain, nitric oxide acts as a neurotransmitter; in the immune system, nitric oxide acts as a mediator of host defense; in the cardiovascular system, nitric oxide mediates the protective effects of the intact endothelium, acting as an endog...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Böger RH

更新日期：2008-01-01 00:00:00

abstract：PURPOSE OF REVIEW:This article aims at reviewing the recent findings that have been made concerning the crosstalk of carbohydrate metabolism with the generation of small, dense low-density lipoprotein (LDL) particles, which are known to be associated with an adverse cardiovascular risk profile. RECENT FINDINGS:Studies...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Gerber PA,Berneis K

更新日期：2012-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Here, we discuss recent work focused on the role of activating transcription factor 4 (ATF4) in skeletal muscle atrophy. RECENT FINDINGS:Muscle atrophy involves and requires widespread changes in skeletal muscle gene expression; however, the transcriptional regulatory proteins responsible for those c...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Adams CM,Ebert SM,Dyle MC

更新日期：2017-05-01 00:00:00

abstract：:Catabolism of fat-free mass affects both the quality of life and survival of patients. Because of variations in fluid status during acute illness, changes in body weight are difficult to evaluate and interpret during treatment. Nutritional assessment should therefore evaluate fat-free and fat mass changes during metab...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Kyle UG,Pichard C

更新日期：2000-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The loss of skeletal muscle with injury or critical illness can be dramatic. This review emphasizes the importance of skeletal muscle as a metabolic reserve. Changes in protein metabolism with bed rest alone and during physiological stress are discussed. Nutritional and hormonal interventions that ame...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ferrando AA,Paddon-Jones D,Wolfe RR

更新日期：2006-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Ergonomics in total parenteral nutrition include the work performed in the (hospital) pharmacy and on the medical ward. This article reviews the developments in total parenteral nutrition ergonomics and the related cost-savings. RECENT FINDINGS:Research focuses on the ergonomic advantages of multi-co...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Genton L,Mühlebach S,Dupertuis YM,Pichard C

更新日期：2006-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize recent advances in our understanding of mammalian erythritol metabolism and its use as a predictive biomarker of cardiometabolic disease risk. RECENT FINDINGS:Elevated serum erythritol predicts future central adiposity gain and type 2 diabetes mellitus in healthy adults. Erythritol is a ...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Ortiz SR,Field MS

更新日期：2020-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Skeletal muscle metabolic energy, needed to maintain contractile activity, is mainly obtained from glucose and long-chain fatty acids. Recent studies have revealed a remarkable parallel between the regulation of uptake of glucose and fatty acids by muscle, in that each is mediated by sarcolemmal trans...

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Glatz JF,Bonen A,Luiken JJ

更新日期：2002-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Malnutrition is highly prevalent in hospitalized patients. Despite this, it is not routinely assessed in most hospitals worldwide. One of the reasons that might explain this fact is that there is no gold-standard nutritional assessment tool, and much has been written advocating this or that technique....

journal_title：Current opinion in clinical nutrition and metabolic care

authors： Waitzberg DL,Correia MI

更新日期：2003-09-01 00:00:00