Abstract:
:Thmidine (TdR) incorporation into DNA increased in the livers and spleens of rats bearing Yoshida sarcoma (solid type) or AH130 (solid type). TdR kinase and DNA polymerase activities increased in the serum, liver, and spleen of these rats, while thymidine monophosphate kinase activity increased appreciably only in the liver and spleen. On diethylaminoethyl cellulose column chromatography, 2 peaks of TdR dinase activity were separated from the serum and tumor tissues of rats bearing Yoshida sarcoma (solid type) while only 1 peak was obtained from the liver. TdR kinase activity in the serum decreased abruptly 7 hr after removal of the Yoshida sarcoma, while that in the liver decreased more slowly.
journal_name
Cancer Resjournal_title
Cancer researchauthors
Shirasaka T,Fujii Ssubject
Has Abstractpub_date
1975-03-01 00:00:00pages
517-20issue
3eissn
0008-5472issn
1538-7445journal_volume
35pub_type
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