Abstract：
PURPOSE:The purpose of this investigation was to examine the effects of differing amounts of beta-hydroxy-beta-methylbutyrate (HMB), 0, 36, and 76 mg x kg(-1) x d(-1), on hematology, hepatic and renal function during 8 wk of resistance training. METHODS:Thirty-seven, untrained collegiate males and were randomly assigned to one of the three groups, 0, 38, or 76 mg x kg(-1) x d(-1). Resistance training consisted of 10 exercises, performed 3 d x wk(-1) for 8 wk at 80% of their 1-repetition maximum. Blood and urine was obtained before training, 48 h after the initial session, 1 wk, 2 wk, 4 wk, and at 8 wk of resistance training. Blood was analyzed for glucose, blood urea nitrogen, hemoglobin, hepatic enzymes, lipid profile, total leukocytes, and individual leukocytes. Urine was analyzed for pH, glucose, and protein excretion. RESULTS:The 38 mg x kg(-1) x d(-1) group had a greater increase in basophils compared with 0 or 76 mg x kg(-1) x d(-1) groups (P < 0.05). No difference occurred in any other blood and urine measurements. CONCLUSION:These data indicate that 8 wk of HMB supplementation (< or = 76 mg x kg(-1) x d(-1)) during resistance training had no adverse affects on hepatic enzyme function, lipid profile, renal function, or the immune system.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Gallagher PM,Carrithers JA,Godard MP,Schulze KE,Trappe SWdoi
10.1097/00005768-200012000-00023subject
Has Abstractpub_date
2000-12-01 00:00:00pages
2116-9issue
12eissn
0195-9131issn
1530-0315journal_volume
32pub_type
临床试验,杂志文章,随机对照试验abstract：PURPOSE:Previous studies have suggested that extreme endurance exercise may induce cardiac microdamage that could lead to subsequent myocardial fibrosis. Soluble suppression of tumorigenicity 2 (sST2) is a cardiac biomarker for assessment of myocardial fibrosis, inflammation, and strain. We evaluated baseline and exerc...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001806
更新日期：2019-03-01 00:00:00
abstract：PURPOSE:Objective measurement with body worn instrumentation is a preferred and increasingly common way to gather information about young people's physical activity. Measured samples have been typically small and recruited through schools. The purpose of this article was to present the descriptive epidemiology of child...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181d58a92
更新日期：2010-09-01 00:00:00
abstract：INTRODUCTION/PURPOSE:Critical power (CP) is a fundamental parameter defining high-intensity exercise tolerance; however, its physiological determinants are incompletely understood. The present study determined the impact of hyperoxia on CP, the time constant of phase II pulmonary oxygen uptake kinetics (τV˙O2), and mus...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002234
更新日期：2020-05-01 00:00:00
abstract：BACKGROUND:Because physical activity researchers are increasingly using objective portable devices, this review describes the current state of the technology to assess physical activity, with a focus on specific sensors and sensor properties currently used in monitors and their strengths and weaknesses. Additional sens...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：10.1249/MSS.0b013e3182399bc8
更新日期：2012-01-01 00:00:00
abstract：:Conflicting data on the alterations in the maximal exercise response to beta blockade (BB) may be the result of differences in the length of time the subject has been on medication, i.e., hours vs days. The purpose of this study was to examine maximal exercise responses during acute and chronic administration of BB. T...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1988-12-01 00:00:00
abstract：:Stress fractures (SF) are one of the most common and potentially serious overuse injuries. PURPOSE:This study aimed to develop a computational biomechanical model of strain in human tibial bone that will facilitate better understanding of the pathophysiology of SF. METHODS:The MRI of a healthy, young male was used f...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001628
更新日期：2018-09-01 00:00:00
abstract：:In this study the gross efficiency of swimming was determined in a group of male (N = 6) and female (N = 4) competitive swimmers. The gross efficiency is defined as the ratio of the power output (W) to the power input (W). In a range of swimming velocities (0.95-1.6 m.s-1), the power input (rate of energy expenditure,...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：PURPOSE:Carnosine is a dipeptide composed of β-alanine and L-histidine and is present in skeletal muscle. Chronic oral β-alanine supplementation can induce muscle carnosine loading and is therefore seen as the rate-limiting factor for carnosine synthesis. However, the effect of L-histidine supplementation on carnosine ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001213
更新日期：2017-03-01 00:00:00
abstract：PURPOSE:Hyperventilation increases the clearance of carbon monoxide (CO) from blood; thus, we hypothesized that CO elimination would be enhanced with exercise. Accordingly, this study examined the effect of exercise on the half-life of carboxyhemolobin elimination. METHODS:Six healthy subjects (three males and three f...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0b013e3182602a00
更新日期：2012-11-01 00:00:00
abstract：:Inappropriate cushioning and/or tractional characteristics of sports surfaces are assumed to increase surface-related injuries in various sports activities. Various tests assessing cushioning and frictional properties are currently in use to evaluate sports surfaces with respect to their potential to reduce the number...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：
更新日期：1990-02-01 00:00:00
abstract：PURPOSE:To examine serum creatine kinase (CK) activity after resistance exercise bouts with different rest intervals between sets and exercises in high responding (HR) and normal responding (NR) subjects. METHODS:During each resistance exercise bout, three sets with 10-repetition maximum (10RM) loads were completed fo...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181ca7e16
更新日期：2010-07-01 00:00:00
abstract：PURPOSE:Circulating angiogenic cells (CAC) comprise multiple subpopulations of exercise-inducible peripheral blood mononuclear cells (PBMC) that promote angiogenesis and maintain endothelial integrity. We examined the effect of acute maximal exercise on CD31, CD62E, CD14/CD31, CD34/VEGFR2, CD3/CD31, and CD3 PBMC in you...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001029
更新日期：2016-12-01 00:00:00
abstract：PURPOSE:The frequency of interruptions in sedentary time (sedentary breaks) is an aspect of sedentary behaviors that may be associated with metabolic health outcomes. The aim of this study was to describe the change in the frequency of sedentary breaks during a 10-yr period from ages 5 to 15 yr. METHODS:The longitudin...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318245ca20
更新日期：2012-06-01 00:00:00
abstract：:Hypertension is present in epidemic proportions in adults of industrialized societies and is associated with a markedly increased risk of developing numerous cardiovascular pathologies. There is a continuing debate as to the efficacy of aggressive pharmacological therapy in individuals with mild to moderate elevations...
journal_title：Medicine and science in sports and exercise
pub_type： 指南,杂志文章,实务指引,评审
doi：
更新日期：1993-10-01 00:00:00
abstract：PURPOSE:To examine the effect of pelvic stabilization and two lower-limb configurations on the EMG activity of back and hip extensor muscles during a dynamic back extension exercise on a machine and to compare them between sexes. METHODS:Twenty-two healthy volunteers (11 men and 11 women) performed five trunk flexion-...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318188446a
更新日期：2009-02-01 00:00:00
abstract：OBJECTIVE:The present study evaluated the effects of an acute bout of moderate-intensity treadmill walking on aspects of cognitive control underlying successful academic achievement. METHODS:The study used a within-subjects counterbalanced design with a sample of 36 preadolescent children. Cognitive performance was as...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0b013e318258bcd5
更新日期：2012-10-01 00:00:00
abstract：:Existing cross-sectional studies on plasma catecholamine activity provide no support for the concept that a markedly high level of aerobic fitness modifies sympathoadrenal response to an acute psychological challenge in humans. In contrast, compromised sympathetic nervous system activity has been observed in individua...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：
更新日期：1991-07-01 00:00:00
abstract：:This study investigates the utility of two equations for predicting minimum wrestling weight and three equations for predicting body density for the population of high school wrestlers. A sample of 54 wrestlers was assessed for body density by underwater weighing, residual volume by helium dilution, and selected anthr...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1986-04-01 00:00:00
abstract：PURPOSE:We investigated the development and recovery of peripheral and central fatigue during repeated cycling sprints and its influence on power output. METHODS:On six separate days, 12 healthy males performed the following tests: 1, 4, 6, 8, and 10 × 10 s sprints with 30 s of passive recovery between sprints, as wel...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000800
更新日期：2016-03-01 00:00:00
abstract：:Data obtained from 16-mm film of world caliber Olympic weight lifters performing at major competitions were analyzed to study energy changes during body segment and barbell movements, energy transfer to the barbell, and energy transfer between segments during the lifting movements contested. Determination of barbell a...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：PURPOSE AND METHODS:It is commonly recognized that there is familial aggregation for physical activity level. However, the genes and sequence variants responsible for the familial clustering have not been investigated. We performed a genome-wide linkage scan based on 432 markers typed in 767 subjects from 207 families ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.MSS.0000078937.22939.7E
更新日期：2003-08-01 00:00:00
abstract：:Ingestion of fluids providing carbohydrate and electrolytes extends endurance times during prolonged exercise. To understand the contribution of these factors, we examined hormonal, physiologic, and metabolic responses to ingesting water (W) or a 7% glucose polymer/fructose/electrolyte solution (GPFE) in 10 men (age: ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：UNLABELLED:High-speed auto racing has been demonstrated to produce accelerated heart rate (HR) during competition. However, it has not been determined whether the increase in HR was due to physical work efforts or a result of emotional stress. PURPOSE:The purpose of this investigation was to examine the physiological ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200212000-00033
更新日期：2002-12-01 00:00:00
abstract：:The purpose of this investigation was to determine the influence of post-exercise carbohydrate (CHO) intake on the rate of muscle glycogen resynthesis after high intensity weight resistance exercise in subjects not currently weight training. In a cross-over design, eight male subjects performed sets (mean = 8.8) of si...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1993-03-01 00:00:00
abstract：PURPOSE:Obesity is epidemic in Western societies, with rapid rates of increase in the young. Various methods exist for the assessment of body composition, but these have not been compared in obese children and adolescents. This study compared methods of body composition assessment in obese young people to determine whe...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.mss.0000191160.07893.2d
更新日期：2006-03-01 00:00:00
abstract：PURPOSE:The goal of this study was to explore the effect of lifelong aerobic exercise (i.e., chronic training) on skeletal muscle substrate stores (intramyocellular triglyceride [IMTG] and glycogen), skeletal muscle phenotypes, and oxidative capacity (ox), in older endurance-trained master athletes (OA) compared with n...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000789
更新日期：2016-03-01 00:00:00
abstract：INTRODUCTION/PURPOSE:Regular aerobic exercise reduces aortic stiffness. However, the mechanisms by which chronic exercise lowers arterial stiffness are not known. To determine the molecular mechanisms of these changes, the alteration of gene expression in the aorta by aerobic exercise training was measured with the mic...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.mss.0000175052.37087.f8
更新日期：2005-10-01 00:00:00
abstract：:The purpose of this study was to determine whether physical activity behavior tracks during early childhood. Forty-seven children (22 males, 25 females) aged 3-4 yr at the beginning of the study were followed over a 3-yr period. Heart rates were measured at least 2 and up to 4 d.yr-1 with a Quantum XL Telemetry heart ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199601000-00019
更新日期：1996-01-01 00:00:00
abstract：PURPOSE:Investigate hemodynamic responses of resistance exercise (RE) with moderate load (i.e., international guidelines for RE of patients) versus RE with high load in patients with coronary artery disease (CAD). METHODS:Medically stable male (n = 11) and female patients (n = 4) treated with PCI or percutaneous coron...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0000000000000811
更新日期：2016-04-01 00:00:00
abstract：PURPOSE:This is a case study of an aerobically trained, multisport, female athlete (age = 39) diagnosed with stage IIIc human epidermal growth factor receptor 2 positive breast cancer. The focus of the study is on measures of cardiorespiratory fitness (V˙O2peak) through the course of cancer therapy. METHODS:A symptom-...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000987
更新日期：2016-10-01 00:00:00
