Abstract:
PURPOSE:The goal of this study was to explore the effect of lifelong aerobic exercise (i.e., chronic training) on skeletal muscle substrate stores (intramyocellular triglyceride [IMTG] and glycogen), skeletal muscle phenotypes, and oxidative capacity (ox), in older endurance-trained master athletes (OA) compared with noncompetitive recreational younger (YA) athletes matched by frequency and mode of training. METHODS:Thirteen OA (64.8 ± 4.9 yr) exercising 5 times per week or more were compared with 14 YA (27.8 ± 4.9 yr) males and females. IMTG, glycogen, fiber types, succinate dehydrogenase, and capillarization were measured by immunohistochemistry in vastus lateralis biopsies. Fat-ox and carbohydrate (CHO)-ox were measured by indirect calorimetry before and after an insulin clamp and during a cycle ergometer graded maximal test. RESULTS:V˙O2peak was lower in OA than YA. The OA had greater IMTG in all fiber types and lower glycogen stores than YA. This was reflected in greater proportion of type I and less type II fibers in OA. Type I fibers were similar in size, whereas type II fibers were smaller in OA compared with YA. Both groups had similar succinate dehydrogenase content. Numbers of capillaries per fiber were reduced in OA but with a higher number of capillaries per area. Metabolic flexibility and insulin sensitivity were similar in both groups. Exercise metabolic efficiency was higher in OA. At moderate exercise intensities, carbohydrate-ox was lower in OA but with similar Fat-ox. CONCLUSIONS:Lifelong exercise is associated with higher IMTG content in all muscle fibers and higher metabolic efficiency during exercise that are not explained by differences in muscle fibers types and other muscle characteristics when comparing older with younger athletes matched by exercise mode and frequency.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Dubé JJ,Broskey NT,Despines AA,Stefanovic-Racic M,Toledo FG,Goodpaster BH,Amati Fdoi
10.1249/MSS.0000000000000789subject
Has Abstractpub_date
2016-03-01 00:00:00pages
472-80issue
3eissn
0195-9131issn
1530-0315journal_volume
48pub_type
杂志文章abstract:PURPOSE:Resting cardiac vagal modulation (RCVM) and postexercise vagal reactivation (PEVR) are markers of parasympathetic activity. We investigated whether adaptations in these markers to aerobic training are influenced by baseline autonomic control. METHODS:Forty healthy men (19.2 ± 0.8 yr) of similar cardiorespirato...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000000532
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:Tendinopathies are painful overuse injuries observed in athletes participating in jumping sports. These injuries are heavily dependent on the resulting strain from the applied mechanical load. Therefore, mechanisms to reduce tendon strain may represent a primary prevention strategy to reduce the incidence of...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000002004
更新日期:2019-09-01 00:00:00
abstract::A 23-yr-old female body builder injured her right wrist while training. A correct diagnosis of pure distal radio-ulnar dislocation, ulnar volar, was made, and reduction was successfully carried out. After removal of plaster, the patient complained of wrist pain and clicking. Surgical exploration revealed a ruptured tr...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1990-04-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-199910000-00006
更新日期:1999-10-01 00:00:00
abstract:PURPOSE:Stroke volume response to exercise depends on changes in cardiac filling, intrinsic myocardial contractility, and left ventricular afterload. The purpose of this study was to compare these responses during an upright cycle test performed until exhaustion in children and adults. METHODS:Stroke volume, cardiac o...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200203000-00012
更新日期:2002-03-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001303
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0b013e3182a03b8b
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/MSS.0000000000001000
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/mss.0b013e318074ccd9
更新日期:2007-09-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
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journal_title:Medicine and science in sports and exercise
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doi:
更新日期:1983-01-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1097/00005768-200202000-00008
更新日期:2002-02-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1992-08-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
doi:10.1249/MSS.0000000000001052
更新日期:2016-11-01 00:00:00
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journal_title:Medicine and science in sports and exercise
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doi:10.1249/01.mss.0000210197.02576.da
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000121951.10417.b5
更新日期:2004-04-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.MSS.0000078937.22939.7E
更新日期:2003-08-01 00:00:00
abstract:INTRODUCTION:Androgen deprivation therapy (ADT) is associated with significant bone loss and an increase in fracture risk among prostate cancer survivors (PCS). We investigated whether impact + resistance training could stop ADT-related declines in bone mineral density (BMD) among PCS on ADT. METHODS:We randomized 51 ...
journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000000265
更新日期:2014-08-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1993-12-01 00:00:00
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journal_title:Medicine and science in sports and exercise
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pub_type: 杂志文章
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1995-03-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005768-200106000-00004
更新日期:2001-06-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0000000000000373
更新日期:2015-01-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.MSS.0000099107.03704.AE
更新日期:2003-12-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
doi:10.1249/MSS.0b013e3181adb9fb
更新日期:2010-01-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000152731.33450.95
更新日期:2005-02-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:
更新日期:1980-04-01 00:00:00
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/01.mss.0000170096.96662.05
更新日期:2005-07-01 00:00:00