Genome-wide linkage scan for physical activity levels in the Quebec Family study.

Abstract:

PURPOSE AND METHODS:It is commonly recognized that there is familial aggregation for physical activity level. However, the genes and sequence variants responsible for the familial clustering have not been investigated. We performed a genome-wide linkage scan based on 432 markers typed in 767 subjects from 207 families of the Quebec Family study with the aim of identifying loci affecting physical activity levels. Four physical activity level phenotypes were used. RESULTS:Promising evidence of linkage (P < 0.0023) was found for physical inactivity on chromosome 2p22-p16. Suggestive linkages (0.0023

journal_name

Med Sci Sports Exerc

authors

Simonen RL,Rankinen T,Perusse L,Rice T,Rao DC,Chagnon Y,Bouchard C,Quebec Family Study.

doi

10.1249/01.MSS.0000078937.22939.7E

subject

Has Abstract

pub_date

2003-08-01 00:00:00

pages

1355-9

issue

8

eissn

0195-9131

issn

1530-0315

journal_volume

35

pub_type

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