Abstract：
:Synchronous appearance of 2 different malignancies in one patient is a rare phenomenon. We describe our experience of 2 patients with synchronous malignancies of the testis and thyroid gland, and of a third patient who developed a thyroid neoplasm unrelated to recent treatment for a germ cell tumor. The medical records of 3 male patients treated for both a germ cell tumor and a thyroid cancer between 1989 and 1994 were reviewed. Two patients with nonseminomatous germ cell tumor received postoperative chemotherapy after orchiectomy and developed a papillary carcinoma of the thyroid during treatment. A third patient, who received radiation therapy for a clinical stage 1 seminoma, recurred with biopsy proven seminoma in the neck in association with a thyroid nodule 2 years later. All 3 patients had their thyroid cancer treated by surgical resection, and one received adjuvant radioactive iodine. Two of the patients are currently alive and disease-free. One patient died of pulmonary complications that stemmed from bleomycin toxicity. Synchronous appearance of germ cell tumor and papillary carcinoma of the thyroid has not been previously described. Genetic predisposition may play a role in the development of such simultaneous neoplasms.
journal_name
Am J Otolaryngoljournal_title
American journal of otolaryngologyauthors
Ayoub JP,Amato RJ,Chiu A,Sellin RV,Weber RSdoi
10.1053/ajot.2000.18887subject
Has Abstractpub_date
2000-11-01 00:00:00pages
416-20issue
6eissn
0196-0709issn
1532-818Xpii
S0196-0709(00)47597-6journal_volume
21pub_type
杂志文章abstract：:Sarcoidosis is a systemic chronic granulomatous disease of unknown etiology. Although it most commonly affects African-Americans, Scandinavians, and the Irish, individuals of all races and ethnicities are susceptible. The otolaryngologist will most frequently encounter sarcoidosis involving the sinonasal region; howev...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1053/ajot.2002.28783
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND:Cluster schedule of allergen-specific immunotherapy (AIT) is a cost-effective choice for allergic rhinitis (AR) patients, but its safety has been questioned due to the greater dosages required at each treatment compared with conventional immunotherapy. It remains a question that whether cluster schedule lead...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,meta分析
doi：10.1016/j.amjoto.2019.07.013
更新日期：2019-01-01 00:00:00
abstract：:Melanotic neuroectodermal tumor of infancy is a rare condition that is most commonly found within the head and neck regions. We present a 4-month-old boy with a melanotic neuroectodermal tumor of infancy of his maxilla. Because of the fairly high recurrence rate, the operating microscope was used after surgical excisi...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1053/ajot.2001.20696
更新日期：2001-01-01 00:00:00
abstract：:Rupture of the carotid artery has been one of the most feared postoperative complications in head and neck cancer patients. Traditional management of carotid artery rupture has been disappointing, and morbidity and mortality have been high. Experience with carotid artery rupture at the authors' institution over the pa...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(86)80009-6
更新日期：1986-05-01 00:00:00
abstract：:Two cases of inner ear injury caused by suppressed sneezing are described. One patient experienced vestibular symptoms in the form of reflexogenic vertigo that was relieved by surgical section of the tensor tympani tendon. The other patient had a sudden severe permanent sensorineural hearing loss. It is proposed that ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(85)80027-2
更新日期：1985-11-01 00:00:00
abstract：:An immunohistologic study was performed on temporal bones from 30 LP/J mice and 17 CBA/J mice to assess the role of immunologic injury in the pathogenesis of dysplastic bony lesions in LP/J mice. Temporal bones were harvested from animals aged 2 to 31 months to evaluate the progression of the disease. As early as 2 mo...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(87)80053-4
更新日期：1987-09-01 00:00:00
abstract：PURPOSE:The aim of this study is to evaluate the evolution of supracricoid partial laryngectomy (SCPL) in indications, surgical techniques and outcomes through last decades. MATERIALS AND METHODS:A retrospective analysis of 146 patients affected by laryngeal cancer treated with SCPL was carried on. We defined: (1) gro...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2014.07.010
更新日期：2014-11-01 00:00:00
abstract：BACKGROUND:The pedicled nasoseptal mucoperiosteal flap is currently widely used for the reconstruction of a skull base defect following transsphenoidal surgery. The flap is generally secured in position by a Foley catheter balloon. We describe an alternative technique using cylinders of Gelfoam™ (Pfizer Incorporated) t...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102417
更新日期：2020-01-01 00:00:00
abstract：PURPOSE:Bone-cement (BC) ossiculoplasty is one of the options to solve ossicular chain problems. Many authors reported successful results in the early or mid-follow-up period; however, there is no long-term result in the literature. We aim to evaluate long term results of BC ossiculoplasty. MATERIALS AND METHODS:Forty...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102620
更新日期：2020-01-01 00:00:00
abstract：:Intense sounds were delivered to 11 subjects with normal hearing both before and during administration of standard doses of four nonsteroidal anti-inflammatory drugs. After four days of aspirin treatment (3.9 g daily), the subjects' resting hearing levels raised by about 10 dB. Administration of intense sounds that ha...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(84)80033-2
更新日期：1984-07-01 00:00:00
abstract：:Olfactory neuroblastoma is a rare malignant tumor of the nasal cavity arising from the olfactory neuroepithelium. It usually presents as a polypoid mass high in the nasal vault including the cribriform plate, superior turbinate, and superior portion of nasal septum. An 89-year-old man visited our office with symptoms ...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2006.07.013
更新日期：2007-05-01 00:00:00
abstract：:Volumetric changes of the middle ear and mastoid were measured monthly by the direct volumetric method in 28 ears from 21 patients (12 children and nine adults) with otitis media with effusion. The mean volumetric increase immediately after the insertion of the tubes was 1.56 ml and was attributed to the volume of eff...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(86)80053-9
更新日期：1986-07-01 00:00:00
abstract：:Inverted papillomas (IPs) in the nose or the paranasal sinuses exhibit a tendency for rapid growth with bone destruction, a high recurrence rate, and an association with malignancy, requiring early diagnosis and aggressive surgical therapy. A number of operative approaches have been reported in the literature, with gr...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/0196-0709(89)90008-2
更新日期：1989-07-01 00:00:00
abstract：INTRODUCTION:Hypopharyngeal squamous cell carcinoma (SCC) is rare, but highly aggressive. Due to the advanced stage of this cancer at the time of diagnosis, radical surgery with reconstruction of pharynx is the standard care with high morbidity and mortality rate. A safer partial pharyngectomy could also be used for in...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102505
更新日期：2020-01-01 00:00:00
abstract：:Previous studies have shown that propylene glycol causes inflammatory changes and cholesteatoma when applied to chinchilla middle ears. Vitamin A and synthetic analogues are essential for the normal differentiation of epithelial tissues. The purpose of this study was to determine whether the administration of isotreti...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/0196-0709(90)90163-p
更新日期：1990-01-01 00:00:00
abstract：PURPOSE:Bone conduction hearing devices are a well-established treatment option for conductive or mixed hearing losses as well as single-sided deafness. The Osia® 2 System is an active osseointegrated device where a surgically implanted titanium fixture supports a newly developed piezoelectric actuator that is placed u...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102818
更新日期：2021-01-01 00:00:00
abstract：BACKGROUND:Because of the potential role of orexin neuronal circuitry in the regulation of sleep and wakefulness and arousal and breathing, it seems reasonable to speculate that abnormalities in the prepro-orexin gene could be relevant to studies of obstructive sleep apnea/hypopnea syndrome (OSAHS); and it might be a c...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2010.12.005
更新日期：2012-01-01 00:00:00
abstract：PURPOSE:Middle ear disease is increasingly being managed via transcanal endoscopic ear surgery (TEES). A limitation of TEES is that it restricts the surgeon to single-handed dissection. One solution to this would be an endoscope holder to facilitate two-handed dissection. Current endoscope holders are stationary, and c...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102875
更新日期：2020-12-29 00:00:00
abstract：PURPOSE:The aim of our study was to determine whether the combination of intratympanic (IT) corticosteroid with melatonin could be associated with decreased tinnitus in patients with unilateral acute idiopathic tinnitus developed within 3months. MATERIALS AND METHODS:We evaluated this hypothesis through a prospective,...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.amjoto.2014.06.009
更新日期：2014-09-01 00:00:00
abstract：:Recent studies by other investigators have shown that interleukin-1 (IL-1) promotes bone resorption by stimulating various cells. Interleukin-1 not only stimulates collagenase production by fibroblasts and macrophages, but also acts as an osteoclast-activating factor. In this study, IL-1 was localized in human cholest...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/0196-0709(90)90001-c
更新日期：1990-03-01 00:00:00
abstract：:Meniere's disease is a peripheral audiovestibular disorder characterized by vertigo, hearing loss, tinnitus, and aural fullness. Management of these symptoms includes medical and surgical treatment. Many patients with Meniere's disease can be managed using nonablative therapy, such as intratympanic steroids and endoly...
journal_title：American journal of otolaryngology
pub_type： 杂志文章,评审
doi：10.1016/j.amjoto.2020.102817
更新日期：2021-01-01 00:00:00
abstract：:Substantial support for the concept that the posterior semicircular canal is responsible for benign paroxysmal positional vertigo comes from four sources: clinical observations, temporal bone histopathology, experimental observations, and results of selective denervation of the posterior canal crista (singular neurect...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(85)80042-9
更新日期：1985-03-01 00:00:00
abstract：:This case report describes a patient who was found to have a cerebrospinal fluid (CSF) leak originating from the petrous apex. The patient initially presented with multiple bouts of meningitis. The patient was treated surgically via a middle cranial fossa approach but presented five years later with recurrent meningit...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2014.02.013
更新日期：2014-05-01 00:00:00
abstract：:Two cases of trisomy 18 in which temporal bone defects were limited to the inner ears are described. Several abnormalities were present that have not been described previously in this syndrome. The first case involved a 1-month-old female infant who died of congenital heart defects. Cochlear nerve fibers were absent o...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(85)80018-1
更新日期：1985-09-01 00:00:00
abstract：:A newly devised pupillograph that can record the pupillary responses of both eyes simultaneously in a supine subject is described. Three patients with Meniere's disease in the attack and quasiattack stages showed a similar abnormality of pupillary light contraction on the affected side, compared with the unaffected si...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/s0196-0709(85)80090-9
更新日期：1985-05-01 00:00:00
abstract：PURPOSE:Betel nut consumption contributes to higher rates of oral cavity cancer throughout Micronesia. The purpose of this study is to review local surveys and cancer data to further characterize these issues in the Northern Mariana Islands (CNMI). METHODS:Two commonwealth-wide health inquiries were reviewed: The Non-...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2019.07.011
更新日期：2019-01-01 00:00:00
abstract：PURPOSE:The aim of this study was to evaluate the vestibular functions and dual-task performances of individuals with noise induced hearing loss. MATERIALS AND METHODS:Fifty individuals with noise induced hearing loss and 25 healthy individuals were included in the study. Individuals with noise induced hearing loss we...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2020.102665
更新日期：2020-01-01 00:00:00
abstract：PURPOSE:To determine differences in size of cochlear nerves among subjects with deafness due to connexin 26 (Cx26) mutations, subjects with deafness of unknown origin, and normal hearing subjects by sagittal high-resolution magnetic resonance (HRMR) imaging of the temporal bone. MATERIALS AND METHODS:Cross-sectional a...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2005.09.007
更新日期：2006-05-01 00:00:00
abstract：IMPORTANCE:Sympathetic ophthalmia (SO), a rare bilateral panuveitis following penetrating ocular trauma or ocular surgery to one eye, shares a strikingly similar ocular pathology to that of Vogt-Koyanagi-Harada disease (VKH). Audiovestibular dysfunction is a major extraocular manifestation of VKH; however, to date, onl...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2015.02.007
更新日期：2015-07-01 00:00:00
abstract：:A bilobed free radial forearm flap was designed to reconstruct a defect in the epiglottis and tongue base in 2 patients who underwent supraglottic laryngectomy. The flap was initially sutured in the shape of the epiglottis to prevent aspiration during deglutition. Six months after surgery, after a full course of radia...
journal_title：American journal of otolaryngology
pub_type： 杂志文章
doi：10.1016/j.amjoto.2008.11.004
更新日期：2010-03-01 00:00:00
