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Analysis of T wave changes by activation recovery interval in patients with atrial septal defect.

Abstract：

:We examined the distributions of the activation recovery interval (ARI), which is correlated with the local action potential duration (APD), to clarify the origin of the repolarization changes in ASD. The ECGs, QRST isointegral maps and ARI isochronal maps of 21 children with ASD from 3 to 5 years old in age were studied in comparison with 21 age-matched normal children. A conventional and 87 unipolar body surface ECG were simultaneously recorded. The ARIs were determined from the first derivatives of the ECG waveforms. Abnormal ST-T patterns were observed in 11 of 21 ASD, but only in two normal children. The QRST maps of a split positive area pattern were seen in 15 of ASD but none of the normal. In the ARI maps, all the normal children exhibited a short-ARI area on the left and a long-ARI area on the right side of the chest. In 19 of ASD, the ARI distribution revealed a leftward extension of the long-ARI area on the anterior chest, a relative shortening on the right anterior chest, and a localized prolonged ARI on the left anterior chest. The results suggest that right ventricular (RV) volume overload in ASD produces a localized prolongation of the APD on the RV epicardium.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Izumida N,Asano Y,Wakimoto H,Nishiyama M,Doi S,Tsuchiya S,Hosaki J,Kawano S,Sawanobori T,Hiraoka M

doi

10.1016/s0167-5273(00)00248-5

subject

Has Abstract

pub_date

2000-07-31 00:00:00

pages

115-24

issue

2-3

eissn

0167-5273

issn

1874-1754

pii

S0167527300002485

journal_volume

74

pub_type

临床试验,杂志文章

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