Abstract:
PURPOSE:To evaluate the effectiveness of intraoperative mitomycin C in preventing the recurrence of primary pterygium. METHODS:In this prospective, randomized study, 38 eyes of 35 patients with primary pterygium were evaluated. In 19 eyes, the "bare sclera technique" combined with intraoperative application of 0.2 mg/mL (0.02%) mitomycin C for five minutes was performed (mitomycin C treated group). The other 19 eyes--taken as control group--underwent surgical excision alone. Statistics were analyzed using the Mann-Whitney U test and the Fischer's exact test. RESULTS:Patients were 20-38 years of age. The mean age was 25.29 +/- 5.08 in the mitomycin C treated group and 25.00 +/- 5.19 in the control group. During the mean follow-up of 17.04 months (range, 12-36 months; SD = 5.89), 4 recurrences (21%) were observed in the mitomycin C treated group and 11 (57.8%) in the control group. The difference between the two groups was significant (p = 0.045). No postoperative complication was encountered in both groups except for recurrences. CONCLUSION:Intraoperative mitomycin C was found to be effective in preventing the recurrence of primary pterygium.
journal_name
Corneajournal_title
Corneaauthors
Yanyali AC,Talu H,Alp BN,Karabas L,Ay GM,Caglar Ydoi
10.1097/00003226-200007000-00013subject
Has Abstractpub_date
2000-07-01 00:00:00pages
471-3issue
4eissn
0277-3740issn
1536-4798journal_volume
19pub_type
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