Maternal levels of vitamin E in normal and preeclamptic pregnancy.

Abstract:

:Vitamin E, a potent antioxidant, may play a role in preventing preeclampsia. Maternal blood samples were collected between 28 and 40 weeks' gestation from women with mild preeclampsia (n=17), women with severe preeclampsia (n=16) and the control group (n=15). This control group was consisted of 15 pregnant women without hypertension episode during their pregnancy. Vitamin E levels were significantly higher in normotensive pregnant women (1.00+/-0.20 mg/dL) than in those with mild (0.56+/-0.15 mg/dL) or severe (0.37+/-0.75 mg/dL) preeclampsia (P<0.001). In preeclamptic women, when systolic blood pressure increases, maternal levels of vitamin E significantly decrease (P<0.05), also when diastolic blood pressure increases, maternal levels of vitamin E significantly decrease (P<0.05). Measurement of vitamin E concentration in plasma may be useful as a prognostic marker of the likely development of preeclampsia.

journal_name

Arch Gynecol Obstet

authors

Akyol D,Mungan T,Görkemli H,Nuhoglu G

doi

10.1007/s004040050271

subject

Has Abstract

pub_date

2000-04-01 00:00:00

pages

151-5

issue

4

eissn

0932-0067

issn

1432-0711

journal_volume

263

pub_type

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