Maternal plasma noradrenaline levels at 29 weeks and gestational age at birth.

Abstract:

OBJECTIVE:To investigate the relationship between maternal plasma noradrenaline levels at a mean gestational age of 29 weeks and gestational age and weight at birth. DESIGN:Original research. SAMPLE:Seventy-four pregnant women with a mean gestational age of 29 weeks. METHODS:Psychological anxiety levels (Spielberger State and Trait questionnaire) and plasma stress hormone levels (noradrenaline and adrenaline) were measured in pregnant women at a mean gestational age of 29 weeks. Statistical analysis was applied to investigate links between these variables and gestational age and weight at birth. OUTCOME MEASURES:Self-rating anxiety, State and Trait Spielberger questionnaire, maternal noradrenaline and adrenaline levels, gestational age and weight at birth. RESULTS:There was a significant inverse relationship between maternal noradrenaline levels and the infant gestational age at birth (r = 0.09, p = 0.05). There was no relationship between maternal noradrenaline levels and weight at birth. CONCLUSIONS:There was a significant inverse relationship between maternal noradrenaline levels and gestational age at birth, suggesting the possibility of underlying mechanisms linking maternal noradrenaline and timing of delivery.

journal_name

Arch Gynecol Obstet

authors

Teixeira JM,da Cunha Branco J,Alfituri M,Mohinuddin SM,Prendiville O,Steer P

doi

10.1007/s00404-011-1869-y

subject

Has Abstract

pub_date

2011-12-01 00:00:00

pages

1399-402

issue

6

eissn

0932-0067

issn

1432-0711

journal_volume

284

pub_type

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