Impact of sperm cell source on the results of intracytoplasmic sperm injection.

Abstract:

PURPOSE:There is an ongoing debate whether the source of sperm cells, the etiology or the extent of male factor infertility has influence on the outcome of ICSI cycles. METHODS:The results of intracytoplasmic sperm injection (ICSI) according to the source of spermatozoa in patients with severe male factor infertility were compared in a retrospective study: 249 couples underwent a total of 337 fresh ICSI cycles with the use of fresh motile testicular or fresh motile ejaculated spermatozoa. RESULTS:For all variables, there were no statistically significant differences in the ICSI results between both groups. Fertilization rates were 46.8% for testicular and 47.6% for ejaculated spermatozoa. Live birth rates per embryo transfer were 20.4% using testicular spermatozoa and 22.8% using ejaculated spermatozoa. CONCLUSIONS:Neither the source of spermatozoa nor the etiology of severe male infertility has relevant impact on the results of ICSI cycles as long as fresh motile, morphologically normal spermatozoa are used. Therefore, in case of cryptozoospermia, we recommend to preferentially use ejaculated spermatozoa to prevent those men from an unnecessary testicular biopsy avoiding risks and costs implied.

journal_name

Arch Gynecol Obstet

authors

Gnoth C,Markhinin V,Maxrath B,Skonieczny T,Friol K,Roos J,Rahimi G,Godehardt E

doi

10.1007/s00404-014-3448-5

subject

Has Abstract

pub_date

2015-03-01 00:00:00

pages

663-9

issue

3

eissn

0932-0067

issn

1432-0711

journal_volume

291

pub_type

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