[Acute myocardial infarction in elderly patients: medical and social problems].

Abstract:

:The number of elderly patients with acute myocardial infarction has been increasing. However, the choice of treatment remains controversial. Medical records of 310 consecutive patients with acute myocardial infarction were reviewed. Two retrospective analyses were performed. 1) Patients were divided into the elderly group(70 years or more) and the younger group(under 70 years). In-hospital course and outcome were compared. 2) Pre-hospital performance status and living status were reviewed in the elderly group. Acute phase reperfusion therapy was performed in fewer patients in the elderly group(60.8% vs 71.9%, p < 0.01). The difference was most pronounced in cases of direct coronary angioplasty(28.6% vs 54.7%, p < 0.05). As a result, the rate of reperfusion success(74.8% vs 86.8%, p < 0.01) was lower in the elderly group. Moreover, the rates of in-hospital death(23.6% vs 6.8%, p < 0.005), pulmonary edema(20.3% vs 10.8%, p < 0.05), cardiogenic shock(11.9% vs 6.0%, p < 0.005), pneumonia(17.3% vs 3.0%, p < 0.005), and delirium(29.4% vs 12.0%, p < 0.001) were higher in the elderly group. Five patients in the elderly group and 3 patients in the younger group required rehabilitation because of worsened performance status. Six of them were non-reperfused patients. Elderly patients considered likely to become bed-ridden because of pre-existing physical disability at admission accounted for 28.9% of the total. Moreover, many elderly patients had poor support systems (8.4% were living alone, 21.0% were living only with their spouse or a child, 30.1% were widows or widowers). These results show that a lower acute phase reperfusion rate(especially angioplasty) resulted in a poor prognosis and worse performance status in elderly patients. Also 30% of patients were not good candidates for conventional treatment because of delirium, and that self-help in daily life is a fundamental goal for most elderly patients. Rapid and simple acute phase reperfusion, subsequent immediate mobilization, and early discharge are recommended for elderly patients with acute myocardial infarction.

journal_name

J Cardiol

journal_title

Journal of cardiology

authors

Kagoshima M,Miyashita Y,Takei K,Kawakami T,Ichikawa Y,Katai S,Abe K,Ito K,Sakurai S,Owa M

subject

Has Abstract

pub_date

2000-04-01 00:00:00

pages

267-75

issue

4

eissn

0914-5087

issn

1876-4738

journal_volume

35

pub_type

杂志文章
  • [The influence of the right or left ventricular pressure overload on right and left ventricular diastolic behaviors as examined by pulsed Doppler echocardiography].

    abstract::The influence of morphological and dynamic changes in the interventricular septum (IVS) on right ventricular (RV) and left ventricular (LV) fillings in cases of LV or RV pressure overload was evaluated. Using pulsed Doppler echocardiography, LV and RV inflow signals were recorded in 20 healthy subjects, in 36 cases of...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Mizushige K,Morita H,Wada S,Nakajima S,Hirabayashi K,Senda S,Matsuo H

    更新日期:1987-12-01 00:00:00

  • [Abdominal aortic aneurysm with chronic contained rupture in a ninety-year-old woman: a case report].

    abstract::A 90-year-old woman was admitted to a local clinic with fever, anorexia, and right lower abdominal pain on March 25, 2004. She was referred to our hospital for detailed examination of an abdominal aortic aneurysm on May 18. Computed tomography revealed an abdominal aortic aneurysm measuring 78mm in maximal diameter an...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Saito N,Nishiya Y,Sotokawa M,Yusa H,Murata A,Hoshino S

    更新日期:2006-02-01 00:00:00

  • [Hypertrophic obstructive cardiomyopathy with ruptured mitral chordae tendineae: a case report].

    abstract::A 61-year-old man was treated medically under a diagnosis of hypertrophic obstructive cardiomyopathy 7 years previously. He was transferred to our hospital because of sudden onset of dyspnea. Chest radiography showed marked pulmonary congestion. Echocardiography revealed hypertrophic obstructive cardiomyopathy, with a...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Wakeyama T,Ogawa H,Takaki A,Iwami T,Kimura M,Tanaka T,Uchinoumi H

    更新日期:2004-08-01 00:00:00

  • Impedance cardiography and quantitative tissue Doppler echocardiography for evaluating the effect of cardiac resynchronization therapy: a case report.

    abstract::An 83-year-old woman presented with dilated cardiomyopathy. Cardiac resynchronization therapy was performed. Two weeks later, cardiac output and ventricular wall motion were estimated using impedance cardiography and tissue Doppler echocardiography with and without pacing. Cardiac output increased from 3.5 to 4.5 l/mi...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Adachi H,Hiratsuji T,Sakurai S,Tada H,Toyama T,Naito S,Hoshizaki H,Oshima S,Taniguchi K

    更新日期:2003-07-01 00:00:00

  • Comparative study of hemorrhagic and ischemic complications among anticoagulants in patients undergoing cryoballoon ablation for atrial fibrillation.

    abstract:OBJECTIVE:Few data exist to evaluate the safety and efficacy of direct oral anticoagulants (DOACs) in patients with atrial fibrillation (AF) undergoing cryoballoon ablation (CB-A). This study is aimed to clarify the usefulness of DOACs in patients undergoing CB-A. METHODS:The patients (average age; 65.8±11.9 years old...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2016.04.009

    authors: Okishige K,Nakamura T,Aoyagi H,Kawaguchi N,Yamashita M,Kurabayashi M,Suzuki H,Asano M,Shimura T,Yamauchi Y,Sasano T,Hirao K

    更新日期:2017-01-01 00:00:00

  • A novel method for the quantitative evaluation of diurnal respiratory instability in patients with heart failure: A pilot study.

    abstract:BACKGROUND:There is no established method to quantitatively measure the presence and the severity of respiratory instability (RI). The purpose of this pilot study was to propose a novel index of diurnal RI as a surrogate measure of clinical severity of heart failure (HF). METHODS AND RESULTS:We prospectively enrolled ...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2017.08.002

    authors: Kumagai N,Dohi K,Fujimoto N,Tanimura M,Sato Y,Miyahara S,Nakamori S,Fujii E,Yamada N,Ito M

    更新日期:2018-02-01 00:00:00

  • Efficacy and safety of bivalirudin in coronary artery disease patients with mild to moderate chronic kidney disease: Meta-analysis.

    abstract:BACKGROUND:Patients with chronic kidney disease (CKD) have elevated bleeding and ischemic outcomes. We aim to assess the short- and long-term efficacy and safety of bivalirudin compared to heparin plus glycoprotein IIb/IIIa inhibitors (GPIs) in coronary artery disease (CAD) patients with CKD. METHODS:Randomized trials...

    journal_title:Journal of cardiology

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.jjcc.2017.10.018

    authors: Zeng X,Lincoff AM,Schulz-Schüpke S,Steg PG,Elbez Y,Mehran R,Stone GW,McAndrew T,Lin J,Zhang X,Shi W,Lei H,Jing Z,Huang W

    更新日期:2018-05-01 00:00:00

  • Impact of preprocedural high-sensitive C-reactive protein levels on long-term clinical outcomes of patients with stable coronary artery disease and chronic kidney disease who were treated with drug-eluting stents.

    abstract:BACKGROUND:To evaluate the prognostic impact of preprocedural high-sensitivity C-reactive protein (hsCRP) levels on the long-term clinical outcomes after first-generation drug-eluting stent (DES) implantation in chronic kidney disease (CKD) patients with stable coronary artery disease (CAD). METHODS AND RESULTS:We fou...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2014.10.010

    authors: Ogita M,Miyauchi K,Kasai T,Doi S,Wada H,Naito R,Konishi H,Tsuboi S,Dohi T,Tamura H,Okazaki S,Daida H

    更新日期:2015-07-01 00:00:00

  • Time to and risk of cardiac events after myocardial perfusion scintigraphy.

    abstract:BACKGROUND:The burden of cardiovascular disease is increasing, yet it remains difficult to focus preventive strategies on populations at highest absolute and relative risks. We compared absolute and relative cardiovascular event counts, plus time to first event, among patients undergoing myocardial perfusion scintigrap...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2014.11.007

    authors: Nudi F,Neri G,Schillaci O,Pinto A,Procaccini E,Vetere M,Tomai F,Frati G,Biondi-Zoccai G

    更新日期:2015-08-01 00:00:00

  • Impact of CYP2C19 polymorphism on residual platelet reactivity in patients with coronary heart disease during antiplatelet therapy.

    abstract:BACKGROUND AND PURPOSE:CYP2C19*2 loss-of-function allele in Caucasians may be associated with wide interindividual variability in platelet response to clopidogrel, and the incidence of gene mutation varies with racial differences, especially between Asians and Caucasians. The aim was to examine the impact of CYP2C19 ge...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2010.10.007

    authors: Yamamoto K,Hokimoto S,Chitose T,Morita K,Ono T,Kaikita K,Tsujita K,Abe T,Deguchi M,Miyagawa H,Saruwatari J,Sumida H,Sugiyama S,Nakagawa K,Ogawa H

    更新日期:2011-03-01 00:00:00

  • [Pulmonary vein orifice cryoablation for atrial fibrillation with mitral valve disease using a specially designed cryo-probe].

    abstract:OBJECTIVES:To evaluate the effectiveness of pulmonary vein orifice cryoablation (PVOC) for atrial fibrillation during mitral valve surgery. METHODS:Twenty-two patients (12 men and 10 women) with mitral valve disease complicated with atrial fibrillation have been treated by PVOC since March 2000. During the mitral valv...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Furukawa H,Konishi T,Fukata M,Okura K

    更新日期:2006-05-01 00:00:00

  • [Effect of verapamil on myocardial ischemia in patients with hypertrophic cardiomyopathy: evaluation by exercise thallium-201 SPECT].

    abstract::The effect of verapamil on myocardial ischemia in patients with hypertrophic cardiomyopathy (HCM) was evaluated by exercise myocardial 201Tl SPECT (EX-Tl). EX-Tl was performed before and after 8.1 +/- 6.1 weeks of oral administration of verapamil (240 mg/day) on 20 patients with HCM who showed transient 201Tl perfusio...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Taniguchi Y,Sugihara H,Ohtsuki K,Umamoto I,Nakagawa T,Shiga K,Nakamura T,Azuma A,Kohno Y,Nakagawa M

    更新日期:1994-01-01 00:00:00

  • [Evaluation of echocardiographic left ventricular wall motion analysis supported by internet picture viewing system].

    abstract:BACKGROUND:Assessment of deterioration of regional wall motion by echocardiography is not only subjective but also features difficulties with interobserver agreement. Progress in digital communication technology has made it possible to send video images from a distant location via the Internet. OBJECTIVES:The possibil...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Hirano Y,Ikuta S,Nakano M,Akiyama S,Nakamura H,Nasu M,Saito F,Nakagawa J,Matsuzaki M,Miyazaki S

    更新日期:2007-02-01 00:00:00

  • Effects of eicosapentaenoic acid on peri-procedural (type IVa) myocardial infarction following elective coronary stenting.

    abstract:OBJECTIVES:The aim of this study was to assess the effect of eicosapentaenoic acid (EPA) on peri-procedural (type IVa) myocardial infarction (MI) following elective percutaneous coronary intervention (PCI). METHODS AND RESULTS:We analyzed data from 165 of 178 consecutive patients with stable angina pectoris who underw...

    journal_title:Journal of cardiology

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.jjcc.2014.09.004

    authors: Kurita A,Takashima H,Ando H,Kumagai S,Waseda K,Gosho M,Amano T

    更新日期:2015-08-01 00:00:00

  • Long-term adherence to nasal continuous positive airway pressure therapy by hypertensive patients with preexisting sleep apnea.

    abstract:BACKGROUND AND OBJECTIVE:Although positive screening for and treatment of obstructive sleep apnea (OSA) have been recommended for patients with cardiovascular problems, patient adherence to nasal continuous positive airway pressure (CPAP) therapy primarily for a cardiovascular concern is unknown. Therefore, this study ...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2013.08.013

    authors: Furukawa T,Suzuki M,Ochiai M,Kawashima H,Yokoyama N,Isshiki T

    更新日期:2014-04-01 00:00:00

  • [Percutaneous transvenous mitral commissurotomy in managing rheumatic mitral stenosis].

    abstract::From April 1987 to October 1989, 32 patients with mitral stenosis (MS) were treated, of whom percutaneous transvenous mitral commissurotomy (PTMC) was performed in 14. PTMC was indicated by the surgeons in 5 patients including 1) 2 patients who refused reoperation, 2) one with early gastric cancer, 3) one with severe ...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Ishihara H,Hamanaka Y,Sueda T,Kanehiro K,Shikata H,Matsuura Y,Matsuura H,Okamoto M,Tsuchioka Y,Nakagawa H

    更新日期:1991-01-01 00:00:00

  • Design of therapeutic vaccines as a novel antibody therapy for cardiovascular diseases.

    abstract::Vaccines are primarily used worldwide as a preventive medicine for infectious diseases and have recently been applied to cancer. We and others have developed therapeutic vaccines designed for cardiovascular diseases that are notably different from previous vaccines. In the case of cancer vaccines, a specific protein i...

    journal_title:Journal of cardiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jjcc.2017.01.010

    authors: Nakagami H

    更新日期:2017-09-01 00:00:00

  • Independent and cumulative association of clinical and morphological heart failure with long-term outcome after percutaneous coronary intervention.

    abstract:BACKGROUND:Heart failure (HF) is a risk factor for adverse post-procedural outcome after revascularization; however, it is unclear how left ventricular systolic dysfunction (LVSD) and clinical HF symptoms affect percutaneous coronary intervention (PCI) outcomes. We investigated the characteristics and long-term outcome...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2020.06.014

    authors: Kimura M,Kohno T,Sawano M,Heidenreich PA,Ueda I,Takahashi T,Matsubara T,Ueno K,Hayashida K,Yuasa S,Ohki T,Fukuda K,Kohsaka S

    更新日期:2021-01-01 00:00:00

  • [Tricuspid regurgitation induced by transvenous right ventricular pacing: echocardiographic and pathological observations].

    abstract::To assess tricuspid regurgitation (TR) in patients with permanent transvenous right ventricular (RV) pacing, we performed phonocardiographic, contrast and pulsed Doppler echocardiographic studies in 18 patients with transvenous leads for RV pacing. In addition, a pathological study was performed on 26 autopsy cases wi...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Sakai M,Ohkawa S,Ueda K,Kin H,Watanabe C,Matsushita S,Kuramoto K,Sugiura M,Takahashi T,Takenaka K

    更新日期:1987-06-01 00:00:00

  • Reproducibility of intravascular ultrasound radiofrequency data analysis (virtual histology) with a 45-MHz rotational imaging catheter in ex vivo human coronary arteries.

    abstract:BACKGROUND:Despite the frequent use of spectral analysis of intravascular ultrasound radiofrequency data (VH(®) IVUS) in clinical studies, the assessment for reproducibility using this with high frequency IVUS remains unexplored. PURPOSE:The aim of this study was to examine the reproducibility of VH IVUS using 45-MHz ...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2014.05.004

    authors: Muramatsu T,García-García HM,Brugaletta S,Heo JH,Onuma Y,Fedewa RJ,Nair A,Ozaki Y,Serruys PW

    更新日期:2015-02-01 00:00:00

  • Effects of carvedilol vs bisoprolol on inflammation and oxidative stress in patients with chronic heart failure.

    abstract:BACKGROUND:Inflammation and oxidative stress play a role in the pathophysiology of chronic heart failure (CHF). Our previous clinical trial, the Bisoprolol Improvement Group for Chronic Heart Failure Treatment Study in Dokkyo Medical University (BRIGHT-D), reported that bisoprolol is superior to carvedilol for myocardi...

    journal_title:Journal of cardiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jjcc.2019.07.011

    authors: Toyoda S,Haruyama A,Inami S,Arikawa T,Saito F,Watanabe R,Sakuma M,Abe S,Nakajima T,Tanaka A,Node K,Inoue T

    更新日期:2020-02-01 00:00:00

  • [Long-term follow-up of patients treated with intracoronary thrombolysis or percutaneous transluminal coronary angioplasty for acute myocardial infarction].

    abstract::Long-term follow-up data concerning coronary patients treated for acute myocardial infarction with intracoronary thrombolysis (ICT) or percutaneous transluminal coronary angioplasty (PTCA) are sparse. In this study, the early and long-term outcomes in 95 patients undergoing only ICT (group I) and 190 patients undergoi...

    journal_title:Journal of cardiology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Mori T,Nosaka H,Kimura T,Nobuyoshi M

    更新日期:1991-01-01 00:00:00

  • [Clinical significance of early percutaneous coronary intervention in patients with Braunwald III-B type unstable angina pectoris].

    abstract:OBJECTIVES:To assess the efficacy of early invasive strategy for the treatment of Braunwald III-B type unstable angina pectoris. METHODS:This study included 573 consecutive patients of whom 267 underwent percutaneous coronary intervention (PCI) (312 lesions). The patients were divided into two groups, 95 treated with ...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Nozaki K,Nakao K,Horiuchi K,Kasanuki H,Honda T

    更新日期:2003-06-01 00:00:00

  • Low diastolic blood pressure was one of the independent predictors of ischemia-like findings of electrocardiogram in patients who underwent coronary angiography.

    abstract:BACKGROUND:The underlying cause of a high cardiovascular event rate in the population with low diastolic blood pressure (DBP) has not been fully elucidated. METHODS AND RESULTS:The relationship between DBP and ischemia-like findings on electrocardiography (ECG) was investigated in 187 patients who underwent coronary a...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2013.05.005

    authors: Fujishima S,Murakami N,Haga Y,Nyuta E,Nakate Y,Ishihara S,Kaseda S,Koga T,Ishitsuka T

    更新日期:2013-10-01 00:00:00

  • [Ampulla cardiomyopathy with delayed recovery of microvascular stunning: a case report].

    abstract::A 71-year old woman with schizophrenia was admitted to our hospital on November 26, 2002 under a diagnosis of acute myocardial infarction because of ST segment elevation in leads V2-V5 and positive serum cardiac troponin T level. Emergent coronary angiography showed no significant stenosis, but left ventriculography d...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Amaya K,Shirai T,Kodama T,Kasao M,Tsuchida K,Asano K,Inoue K

    更新日期:2003-10-01 00:00:00

  • Mobilization of sca1/flk-1 positive endothelial progenitor cells declines in apolipoprotein E-deficient mice with a high-fat diet.

    abstract:BACKGROUND:Atherosclerosis features a deterioration of the endothelial layer in all stages. Restoration of the endothelium is associated with circulating stem cell antigen 1 (sca1) and vascular endothelial growth factor receptor type 2 (flk-1) positive endothelial progenitor cells (EPCs). We investigated whether EPC pr...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2015.02.008

    authors: Steinmetz M,Lucanus E,Zimmer S,Nickenig G,Werner N

    更新日期:2015-12-01 00:00:00

  • CELSR2-PSRC1-SORT1 gene expression and association with coronary artery disease and plasma lipid levels in an Asian Indian cohort.

    abstract:BACKGROUND:Genetic regulation of plasma lipids has been shown to influence the risk of coronary artery disease (CAD). We analyzed the relationship between rs599839 and rs646776 single nucleotide polymorphisms (SNPs) present in the CELSR2-PSRC1-SORT1 gene cluster, candidate gene expression, and their association with CA...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:10.1016/j.jjcc.2014.02.012

    authors: Arvind P,Nair J,Jambunathan S,Kakkar VV,Shanker J

    更新日期:2014-11-01 00:00:00

  • [Clinical significance and mechanism of ST-segment changes during the post-exercise recovery period in male patients with coronary artery disease].

    abstract::The treadmill exercise test (TET) is evaluated by exercise-induced ST-segment depression (delta ST). However, the depression sometimes only appears during the post-exercise period. Depression appearing only during the post-exercise period may be as useful as depression during exercise to predict coronary artery diseas...

    journal_title:Journal of cardiology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Shinmura K,Suganuma Y,Hasegawa H,Tani M,Nakamura Y,Akaishi M,Ogawa S

    更新日期:1996-05-01 00:00:00

  • Rationale and design of J-ACCESS 4: prognostic impact of reducing myocardial ischemia identified using ECG-gated myocardial perfusion SPECT in Japanese patients with coronary artery disease.

    abstract:BACKGROUND:The findings of our recent study entitled, "Japanese Assessment of Cardiac Events and Survival Study by Quantitative Gated SPECT (J-ACCESS)" showed that myocardial perfusion single photon emission computed tomography (MPS) can detect coronary artery disease (CAD) and help to predict future cardiac events in ...

    journal_title:Journal of cardiology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jjcc.2013.07.006

    authors: Nanasato M,Nakajima K,Fujita H,Zen K,Kohsaka S,Hashimoto A,Moroi M,Fukuzawa S,Chikamori T,Nishimura S,Yamashina A,Kusuoka H,Hirayama A,Nishimura T

    更新日期:2014-02-01 00:00:00

  • [Aortic flow patterns in normal neonates with patent ductus arteriosus: evaluation by Doppler color flow imaging].

    abstract::Serial Doppler echocardiography was performed in 12 normal neonates (0.5-4.0 hrs after birth) to evaluate flow patterns through the ductus arteriosus, and in the aorta and brachiocephalic artery. At the initial examination, flow through the ductus arteriosus was bidirectional in eight of the 12 neonates and continuous...

    journal_title:Journal of cardiology

    pub_type: 杂志文章

    doi:

    authors: Shiraishi H,Endo H,Ichihashi K,Kuramatsu T,Yanagisawa M

    更新日期:1989-06-01 00:00:00