Abstract:
OBJECTIVES:To assess the efficacy of early invasive strategy for the treatment of Braunwald III-B type unstable angina pectoris. METHODS:This study included 573 consecutive patients of whom 267 underwent percutaneous coronary intervention (PCI) (312 lesions). The patients were divided into two groups, 95 treated with the early invasive strategy of coronary angiography within 24 hr of admission (Group PCI-I) and the remaining 172 treated with the early conservative strategy of coronary angiography 24 hr after admission (Group PCI-C). RESULTS:No significant differences were noted in the baseline characteristics of the two groups except for ST segment elevation on electrocardiography at presentation, which occurred significantly less frequently in Group PCI-C (36.8% vs 8.1%, p < 0.0001). The initial success rate of percutaneous coronary intervention was sufficiently high in both groups (Group PCI-I: 96.9% vs Group PCI-C: 97.7%, NS). Acute myocardial infarction occurred in six patients of Group PCI-C (3.5%) because of the side branch occlusion. There was no in-hospital death or emergent coronary artery bypass grafting. During the 6-month follow-up, there were no significant differences in the death rates (2.1% vs 1.7%), the death or myocardial infarction rates (5.3% vs 5.8%) and the target lesion revascularization ratio (26.0% vs 25.7%) between Group PCI-I and Group PCI-C. CONCLUSIONS:The clinical outcomes of the early invasive strategy for unstable angina pectoris were almost equivalent to those of the early conservative strategy, despite more frequent ST segmental elevation at admission in Group PCI-I. These findings suggest that the early invasive strategy for unstable angina pectoris may be acceptable even in the current Japanese clinical setting without the use of GP IIb/IIIa receptor antagonist, low molecular weight heparin or clopidogrel.
journal_name
J Cardioljournal_title
Journal of cardiologyauthors
Nozaki K,Nakao K,Horiuchi K,Kasanuki H,Honda Tsubject
Has Abstractpub_date
2003-06-01 00:00:00pages
263-70issue
6eissn
0914-5087issn
1876-4738journal_volume
41pub_type
杂志文章abstract::This study verified the usefulness of two-dimensional (2-D) and pulsed Doppler echocardiography (PDE) in the diagnosis of tricuspid stenosis (TS), and estimated the diastolic pressure gradient (PG) across the tricuspid valve (TV). Fifty-two patients with rheumatic mitral stenosis showing a decreased EF slope of the TV...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1987-03-01 00:00:00
abstract:BACKGROUND:While physical rehabilitation has been shown to be beneficial and safe for patients suffering from heart failure, data on rehabilitation for hypertrophic cardiomyopathy (HCM) patients are limited. METHODS:Forty-five HCM patients participated in an exercise rehabilitation program. Exercise capacity was measu...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2019.04.013
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:To study the involvement of vasospasm as the trigger of acute myocardial infarction without significant stenosis, the circadian variation of the time of onset of acute myocardial infarction was compared with that of vasospastic angina without significant stenosis. METHODS:The subjects consisted of 3 groups,...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2000-07-01 00:00:00
abstract::Coronary flow velocity recordings were obtained in three patients with ampulla (Takotsubo) cardiomyopathy using Doppler guide wire. Immediately after admission, coronary angiography demonstrated no significant stenosis and normal coronary flow in the epicardial coronary artery. Left ventriculography showed abnormal wa...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2002-06-01 00:00:00
abstract:BACKGROUND:It is said that the chronic outcomes of the two-stent technique for bifurcation lesions are inferior to that of cross-over single stenting. However, there are many cases where true bifurcations are difficult to treat by single stenting and, in particular, strategies for bifurcation lesions that are not left ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2009.10.005
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:Assessment of deterioration of regional wall motion by echocardiography is not only subjective but also features difficulties with interobserver agreement. Progress in digital communication technology has made it possible to send video images from a distant location via the Internet. OBJECTIVES:The possibil...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2007-02-01 00:00:00
abstract::From April 1987 to October 1989, 32 patients with mitral stenosis (MS) were treated, of whom percutaneous transvenous mitral commissurotomy (PTMC) was performed in 14. PTMC was indicated by the surgeons in 5 patients including 1) 2 patients who refused reoperation, 2) one with early gastric cancer, 3) one with severe ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:The relationship between ongoing myocardial damage and heart failure with preserved left ventricular systolic function (HF-PEF) is still unclear. To investigate this relationship, we measured the cardiac-specific cytosolic marker, heart-type fatty acid binding protein (H-FABP), and a myofibrillar component (...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2012.06.006
更新日期:2012-12-01 00:00:00
abstract::The usefulness of 80 degrees head-up tilt testing with and without low dose isoproterenol provocation was evaluated for the diagnosis of neurally mediated syncope (NMS) in Japanese. Head-up tilt testing was performed in 114 consecutive patients with clinical diagnoses of NMS (68 men, 46 women, mean age 46 +/- 21 years...
journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
doi:
更新日期:2000-05-01 00:00:00
abstract::The correlation between the time-course changes in the serum concentration of myosin light chain 1 (ML-1) and left ventricular (LV) function was investigated in 37 patients with initial anterior acute myocardial infarction (AMI) after successful reperfusion. All patients were confirmed to have coronary arteries recana...
journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
doi:
更新日期:1995-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Many clinical trials have shown that 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) can significantly reduce coronary artery disease in both primary and secondary prevention. A recent study showed that aggressive lipid-lowering therapy with strong statins could ach...
journal_title:Journal of cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.jjcc.2013.12.008
更新日期:2014-09-01 00:00:00
abstract::This is a report of a 65-year-old man with end-stage dilated cardiomyopathy, and first-degree atrioventricular (AV) block, which had been resistant to intensive medical therapy and was eventually treated using a DDD pacemaker. The optimal AV interval setting was determined using invasive right heart catheterization an...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::The clinical significance of long-standing (greater than or equal to 24 hours) coronary T waves without abnormal Q waves was evaluated in 24 patients with angina. They were categorized in two groups; 11 with ST elevation followed by coronary T waves (Group A), and 13 with coronary T waves alone (Group B). 1. The patie...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1988-09-01 00:00:00
abstract::Chronic total occlusion (CTO) is a challenging subset of coronary artery disease that is commonly encountered in real-world practice; it is associated with worse long-term prognosis. Observational studies suggest that percutaneous coronary intervention (PCI) for CTO is associated with reduction in myocardial ischemia ...
journal_title:Journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jjcc.2016.12.006
更新日期:2017-06-01 00:00:00
abstract::A 42-year-old male was hospitalized in the surgical ward for abdominal pain due to stenosis of the splenic flexure of the colon and abscess around the stenosis. After segmental colectomy, the patient received intravenous continuous infusion of trimetaphan (Arfonad) to control his blood pressure. Twenty hours later, he...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract::The exercise stress test with a bicycle ergometer was performed for 31 patients with mitral stenosis and for 10 normal subjects. The patients were categorized in two groups. Group 1 consisted of 16 patients having indication for surgical intervention and Group 2 consisted of 15 patients without such surgical indicatio...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1989-09-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to assess the effect of eicosapentaenoic acid (EPA) on peri-procedural (type IVa) myocardial infarction (MI) following elective percutaneous coronary intervention (PCI). METHODS AND RESULTS:We analyzed data from 165 of 178 consecutive patients with stable angina pectoris who underw...
journal_title:Journal of cardiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.jjcc.2014.09.004
更新日期:2015-08-01 00:00:00
abstract::The effects of elective percutaneous transluminal coronary angioplasty (PTCA) performed one month after coronary reperfusion therapy in patients with acute myocardial infarction (AMI) were observed using exercise Tl-201 myocardial scintigraphy performed before and after PTCA. Myocardial perfusion in Tl-201 scintigraph...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::A 56-year-old man visited a doctor because of arrhythmia and a diagnosis of hypertrophic cardiomyopathy was made in 1990. On January 9th, 1997, when aged 63 years old, he visited another doctor because of paroxysmal atrial fibrillation tachycardia. Since his clinical symptoms did not ameliorate, he visited our hospita...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1998-05-01 00:00:00
abstract:BACKGROUND:Although combination therapy for various cardiac conditions with dual antiplatelet therapy (aspirin and thienopyridine derivatives) and warfarin sodium has become increasingly popular, the safety and effectiveness of this aggressive treatment regimen remain unknown. METHODS AND RESULTS:We retrospectively en...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2009.12.014
更新日期:2010-05-01 00:00:00
abstract::Intimal hyperplasia due to fibrocellular proliferation, mainly of smooth muscle cells, leads to restenosis after successful percutaneous transluminal coronary angioplasty (PTCA). The mechanism of intimal proliferation of smooth muscle cells was investigated by histological and immunohistochemical studies of necropsied...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
abstract::To evaluate noninvasively the patency of aortocoronary bypass grafts using the left internal mammary artery (LIMAG), color flow mapping Doppler echocardiography was performed in 23 consecutive patients. There were 22 males and one female. The average number of involved coronary arteries per patient was 2.5 +/- 0.6. Th...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
abstract::Left ventricular function was evaluated using parameters derived from the flow velocity waveforms at the ascending aorta as obtained at the suprasternal notch by continuous-wave Doppler echocardiography in 39 patients; 12 with chest pain but without coronary stenosis, eight with angina pectoris; and 19 with myocardial...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Myocardial fibrosis is associated with poor prognosis in nonischemic dilated cardiomyopathy (NIDCM) patients. The Selvester QRS score on 12-lead electrocardiogram is associated with both the amount of myocardial scar and poor prognosis in myocardial infarction patients. However, its use in NIDCM patients is ...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2017.09.002
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Although the occurrence of no-reflow during percutaneous coronary intervention (PCI) has been shown to be associated with worse short- and long-term clinical outcomes, the clinical relevance of preventing flow deterioration by using the filter-based distal protection devices (DPDs) is controversial. We inves...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2015.06.015
更新日期:2016-05-01 00:00:00
abstract::Although the mechanism for the occurrence of acute myocardial infarction (MI) has been investigated by many pathological and clinical studies, it has not been adequately clarified yet. Although the disruption of vulnerable plaque is a well-known cause of acute MI, there are many silent plaque disruptions detected in t...
journal_title:Journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jjcc.2020.08.007
更新日期:2020-09-10 00:00:00
abstract::No heart transplants have been performed in Japan due to various obstacles since the only operation performed in 1968. Since 1981, a number of patients requiring heart transplants have been accepted by foreign transplantation centers in England, the U.S.A., and Germany. This report describes an investigation of the po...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Serum levels of lipoprotein (a) [Lp(a)] have been reported as a residual risk marker for adverse events in patients with coronary artery disease (CAD). However, the prognostic impact of Lp(a) on long-term clinical outcomes among diabetic patients on statin therapy after percutaneous coronary intervention (PC...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.jjcc.2020.01.013
更新日期:2020-07-01 00:00:00
abstract::An 83-year-old woman presented with dilated cardiomyopathy. Cardiac resynchronization therapy was performed. Two weeks later, cardiac output and ventricular wall motion were estimated using impedance cardiography and tissue Doppler echocardiography with and without pacing. Cardiac output increased from 3.5 to 4.5 l/mi...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:2003-07-01 00:00:00
abstract::This study investigated the mechanism of aortic regurgitation caused by dilatation of the sinotubular junction. The canine model of dilatation of the sinotubular junction was used to observe coaptation of the aortic valve using direct imaging by endoscopy. Five adult mongrel dogs (body weight: 20-25 kg) were anestheti...
journal_title:Journal of cardiology
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00